AR015105A1 - Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprende - Google Patents
Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprendeInfo
- Publication number
- AR015105A1 AR015105A1 ARP970105320A ARP970105320A AR015105A1 AR 015105 A1 AR015105 A1 AR 015105A1 AR P970105320 A ARP970105320 A AR P970105320A AR P970105320 A ARP970105320 A AR P970105320A AR 015105 A1 AR015105 A1 AR 015105A1
- Authority
- AR
- Argentina
- Prior art keywords
- growth
- neurites
- stimulate
- understands
- medicine
- Prior art date
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 102000007072 Nerve Growth Factors Human genes 0.000 title abstract 3
- 239000003900 neurotrophic factor Substances 0.000 title abstract 3
- 210000002241 neurite Anatomy 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title 1
- 210000004027 cell Anatomy 0.000 title 1
- 102000015336 Nerve Growth Factor Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940053128 nerve growth factor Drugs 0.000 abstract 2
- 210000002569 neuron Anatomy 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 1
- 230000003961 neuronal insult Effects 0.000 abstract 1
- 230000000508 neurotrophic effect Effects 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/749,114 US5780484A (en) | 1996-11-13 | 1996-11-13 | Methods for stimulating neurite growth with piperidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR015105A1 true AR015105A1 (es) | 2001-04-18 |
Family
ID=25012320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105320A AR015105A1 (es) | 1996-11-13 | 1997-11-13 | Una composicion que comprende derivados de urea o carbonato y factores neurotroficos para estimular el crecimiento de neuritas en celulas nerviosas y unmedicamento que la comprende |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5780484A (show.php) |
| EP (2) | EP1666053A1 (show.php) |
| JP (1) | JP2001503778A (show.php) |
| KR (1) | KR100537866B1 (show.php) |
| CN (1) | CN1168443C (show.php) |
| AR (1) | AR015105A1 (show.php) |
| AU (1) | AU741186B2 (show.php) |
| BR (1) | BR9713037A (show.php) |
| CA (1) | CA2270985A1 (show.php) |
| CO (1) | CO5080733A1 (show.php) |
| EA (1) | EA003530B1 (show.php) |
| IL (1) | IL129557A0 (show.php) |
| IN (1) | IN183409B (show.php) |
| NZ (1) | NZ335396A (show.php) |
| PL (1) | PL191249B1 (show.php) |
| TW (1) | TW509572B (show.php) |
| UA (1) | UA61090C2 (show.php) |
| WO (1) | WO1998020893A1 (show.php) |
| ZA (1) | ZA9710248B (show.php) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150527A (en) * | 1994-08-18 | 2000-11-21 | Ariad Pharmaceuticals, Inc. | Synthetic multimerizing agents |
| US6133456A (en) * | 1994-08-18 | 2000-10-17 | Ariad Gene Therapeutics, Inc. | Synthetic multimerizing agents |
| US20030036654A1 (en) | 1994-08-18 | 2003-02-20 | Holt Dennis A. | Synthetic multimerizing agents |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| ZA98825B (en) * | 1997-02-27 | 1998-10-19 | Guilford Pharm Inc | Method of using neurotrophic carbamates and ureas |
| US6242468B1 (en) * | 1997-02-27 | 2001-06-05 | Jia-He Li | Carbamate and urea compositions and neurotrophic uses |
| US6514686B2 (en) | 1997-04-28 | 2003-02-04 | The University Of British Columbia | Method and composition for modulating amyloidosis |
| US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| US6852496B1 (en) * | 1997-08-12 | 2005-02-08 | Oregon Health And Science University | Methods of screening for agents that promote nerve cell growth |
| US5968921A (en) * | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| BR9815881A (pt) * | 1998-06-03 | 2002-07-23 | Gpi Nil Holding Inc | Uréias e carbamatos de ácido carboxìlicos n-heterocìclicos e isoésteres de ácido carboxìlico |
| US7459473B2 (en) | 1998-06-03 | 2008-12-02 | Glia Med, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres |
| US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
| DK1098897T3 (da) | 1998-07-17 | 2004-10-18 | Agouron Pharma | Forbindelser, præparater og fremgangsmåder til stimulation af neuronvækst og -forlængelse |
| GB9815880D0 (en) | 1998-07-21 | 1998-09-16 | Pfizer Ltd | Heterocycles |
| US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
| US7338976B1 (en) | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
| US6395758B1 (en) * | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
| US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
| US6228872B1 (en) * | 1998-11-12 | 2001-05-08 | Bristol-Myers Squibb Company | Neurotrophic diamide and carbamate agents |
| EP1196389A1 (en) * | 1999-07-06 | 2002-04-17 | Vertex Pharmaceuticals Incorporated | N-heterocyclic derivatives with neuronal activity |
| US6734211B1 (en) | 1999-07-09 | 2004-05-11 | Oregon Health & Sciences University | Compositions and methods for promoting nerve regeneration |
| CN1382140A (zh) | 1999-07-09 | 2002-11-27 | 奥索-麦克尼尔药品公司 | 具有神经营养活性的吡咯烷和哌啶、以及含有它们的相关组合物 |
| EP1214293A1 (en) * | 1999-09-08 | 2002-06-19 | Guilford Pharmaceuticals Inc. | Non-peptidic cyclophilin binding compounds and their use |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| ES2269206T3 (es) * | 1999-11-12 | 2007-04-01 | Alcon, Inc. | Ligandos de neurofilina para tratar trastornos oculares. |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| US6818643B1 (en) | 1999-12-08 | 2004-11-16 | Bristol-Myers Squibb Company | Neurotrophic bicyclic diamides |
| CA2393466C (en) | 1999-12-21 | 2010-01-19 | Gpi Nil Holdings, Inc. | Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same |
| EP1360173A2 (en) | 2001-01-25 | 2003-11-12 | Guilford Pharmaceuticals Inc. | Trisubstituted carbocyclic cyclophilin binding compounds and their use |
| WO2002096420A2 (en) * | 2001-05-29 | 2002-12-05 | Guilford Pharmaceuticals Inc. | Method for treating nerve injury caused by surgery |
| US20040147433A1 (en) * | 2001-06-14 | 2004-07-29 | Marcus Keep | Neuroimmunophilins for selective neuronal radioprotection |
| WO2003062773A1 (en) * | 2002-01-24 | 2003-07-31 | Pei Electronics, Inc. | Compact integrated infrared scene projector |
| MXPA05003471A (es) * | 2002-10-03 | 2005-07-01 | Vertex Pharma | Derivados de piperazina y piperadina para el tratamiento de enfermedades neurologicas. |
| US20060189551A1 (en) * | 2004-10-04 | 2006-08-24 | Duke University | Combination therapies for fungal pathogens |
| CN101084226A (zh) | 2004-12-20 | 2007-12-05 | 惠氏公司 | 雷帕霉素衍生物及其治疗神经紊乱的用途 |
| UA94034C2 (ru) * | 2004-12-20 | 2011-04-11 | Уайет | Аналоги рапамицина и их применение в лечении неврологических, пролиферативных и воспалительных расстройств |
| SI2607362T1 (sl) * | 2005-02-17 | 2015-03-31 | Astellas Pharma Inc. | Piperidinski in piperazinski karboksilati kot FAAH inhibitorji |
| JP2009525319A (ja) * | 2006-02-02 | 2009-07-09 | ライナット ニューロサイエンス コーポレイション | trkBアンタゴニストを投与することにより肥満を治療する方法 |
| RU2008131939A (ru) * | 2006-02-02 | 2010-02-10 | Ринат Ньюросайенс Корп. (Us) | Способы лечения нежелательной потери веса или нарушений приема пищи агонистами trkb |
| EP3801217A4 (en) | 2018-05-30 | 2022-07-20 | Zap Surgical Systems, Inc. | RADIOSURGICAL NEUROMODLATION CLOSE TO CRITICAL STRUCTURES |
| CN116763768A (zh) * | 2022-03-15 | 2023-09-19 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸衍生物及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
| DE69229782T2 (de) * | 1991-05-09 | 2000-04-27 | Vertex Pharmaceuticals Inc., Cambridge | Neue immunsuppressive verbindungen |
| NZ314207A (en) * | 1992-09-28 | 2000-12-22 | Vertex Pharma | 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers |
| US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
| IL115685A (en) * | 1994-11-16 | 2000-08-31 | Vertex Pharma | Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| US5543423A (en) * | 1994-11-16 | 1996-08-06 | Vertex Pharmaceuticals, Incorporated | Amino acid derivatives with improved multi-drug resistance activity |
| US5726184A (en) * | 1995-05-19 | 1998-03-10 | Vertex Pharmaceuticals Incorporated | Tetralin compounds with improved MDR activity |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
| US5614547A (en) * | 1995-06-07 | 1997-03-25 | Guilford Pharmaceuticals Inc. | Small molecule inhibitors of rotamase enzyme |
| US6037370A (en) * | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5801197A (en) * | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| US5840736A (en) * | 1996-11-13 | 1998-11-24 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| US5811434A (en) * | 1996-11-13 | 1998-09-22 | Vertex Pharmacueticals Incorporated | Methods and compositions for stimulating neurite growth |
| US9604852B2 (en) * | 2012-09-28 | 2017-03-28 | Dic Corporation | α-alumina particles and method for manufacturing the same |
-
1996
- 1996-11-13 US US08/749,114 patent/US5780484A/en not_active Expired - Lifetime
-
1997
- 1997-11-13 IN IN2147CA1997 patent/IN183409B/en unknown
- 1997-11-13 JP JP52286798A patent/JP2001503778A/ja active Pending
- 1997-11-13 EA EA199900463A patent/EA003530B1/ru not_active IP Right Cessation
- 1997-11-13 CA CA002270985A patent/CA2270985A1/en not_active Abandoned
- 1997-11-13 AU AU54397/98A patent/AU741186B2/en not_active Ceased
- 1997-11-13 WO PCT/US1997/020868 patent/WO1998020893A1/en not_active Ceased
- 1997-11-13 EP EP06000328A patent/EP1666053A1/en not_active Ceased
- 1997-11-13 KR KR10-1999-7004194A patent/KR100537866B1/ko not_active Expired - Fee Related
- 1997-11-13 CO CO97066753A patent/CO5080733A1/es unknown
- 1997-11-13 BR BR9713037-0A patent/BR9713037A/pt not_active Application Discontinuation
- 1997-11-13 EP EP97948309A patent/EP0941113A1/en not_active Ceased
- 1997-11-13 AR ARP970105320A patent/AR015105A1/es not_active Application Discontinuation
- 1997-11-13 NZ NZ335396A patent/NZ335396A/xx unknown
- 1997-11-13 IL IL12955797A patent/IL129557A0/xx not_active IP Right Cessation
- 1997-11-13 CN CNB971802483A patent/CN1168443C/zh not_active Expired - Fee Related
- 1997-11-13 TW TW086116912A patent/TW509572B/zh not_active IP Right Cessation
- 1997-11-13 PL PL333286A patent/PL191249B1/pl not_active IP Right Cessation
- 1997-11-13 UA UA99063269A patent/UA61090C2/uk unknown
- 1997-11-13 ZA ZA9710248A patent/ZA9710248B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ335396A (en) | 2000-11-24 |
| EA003530B1 (ru) | 2003-06-26 |
| PL333286A1 (en) | 1999-11-22 |
| CN1168443C (zh) | 2004-09-29 |
| TW509572B (en) | 2002-11-11 |
| IL129557A0 (en) | 2000-02-29 |
| EP0941113A1 (en) | 1999-09-15 |
| KR100537866B1 (ko) | 2005-12-21 |
| JP2001503778A (ja) | 2001-03-21 |
| KR20000068964A (ko) | 2000-11-25 |
| PL191249B1 (pl) | 2006-04-28 |
| EA199900463A1 (ru) | 2000-02-28 |
| CA2270985A1 (en) | 1998-05-22 |
| CN1239434A (zh) | 1999-12-22 |
| BR9713037A (pt) | 2000-04-11 |
| UA61090C2 (uk) | 2003-11-17 |
| AU741186B2 (en) | 2001-11-22 |
| IN183409B (show.php) | 1999-12-25 |
| AU5439798A (en) | 1998-06-03 |
| ZA9710248B (en) | 1998-05-28 |
| CO5080733A1 (es) | 2001-09-25 |
| WO1998020893A1 (en) | 1998-05-22 |
| US5780484A (en) | 1998-07-14 |
| EP1666053A1 (en) | 2006-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |