AR011090A1 - COMPOSICIONES ANESTÉSICAS DE SEVOFLURANO, METODO PARA SU PREPARACIoN, MÉTODOS PARA INHIBIR SU DEGRADACIoN ANTE LA PRESENCIA DE UN ÁCIDO LEWIS Y UN PROCESO PARA PREPARAR UNA COMPOSICION ANESTÉSICA ESTABLE EN UN CONTENEDOR SELLADO - Google Patents
COMPOSICIONES ANESTÉSICAS DE SEVOFLURANO, METODO PARA SU PREPARACIoN, MÉTODOS PARA INHIBIR SU DEGRADACIoN ANTE LA PRESENCIA DE UN ÁCIDO LEWIS Y UN PROCESO PARA PREPARAR UNA COMPOSICION ANESTÉSICA ESTABLE EN UN CONTENEDOR SELLADOInfo
- Publication number
- AR011090A1 AR011090A1 ARP980100336A ARP980100336A AR011090A1 AR 011090 A1 AR011090 A1 AR 011090A1 AR P980100336 A ARP980100336 A AR P980100336A AR P980100336 A ARP980100336 A AR P980100336A AR 011090 A1 AR011090 A1 AR 011090A1
- Authority
- AR
- Argentina
- Prior art keywords
- lewis acid
- anesthetic
- sevoflurane
- degradation
- inhibit
- Prior art date
Links
- 239000002841 Lewis acid Substances 0.000 title abstract 5
- 150000007517 lewis acids Chemical class 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000003444 anaesthetic effect Effects 0.000 title abstract 4
- 230000015556 catabolic process Effects 0.000 title abstract 2
- 238000006731 degradation reaction Methods 0.000 title abstract 2
- 229960002078 sevoflurane Drugs 0.000 title abstract 2
- DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical group FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229920001774 Perfluoroether Polymers 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 abstract 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 abstract 2
- 239000004322 Butylated hydroxytoluene Substances 0.000 abstract 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 abstract 1
- PIWKPBJCKXDKJR-UHFFFAOYSA-N Isoflurane Chemical compound FC(F)OC(Cl)C(F)(F)F PIWKPBJCKXDKJR-UHFFFAOYSA-N 0.000 abstract 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 abstract 1
- 229940095259 butylated hydroxytoluene Drugs 0.000 abstract 1
- 229960000305 enflurane Drugs 0.000 abstract 1
- JPGQOUSTVILISH-UHFFFAOYSA-N enflurane Chemical compound FC(F)OC(F)(F)C(F)Cl JPGQOUSTVILISH-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229960002725 isoflurane Drugs 0.000 abstract 1
- RFKMCNOHBTXSMU-UHFFFAOYSA-N methoxyflurane Chemical compound COC(F)(F)C(Cl)Cl RFKMCNOHBTXSMU-UHFFFAOYSA-N 0.000 abstract 1
- 229960002455 methoxyflurane Drugs 0.000 abstract 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 abstract 1
- 229960002216 methylparaben Drugs 0.000 abstract 1
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 abstract 1
- 229960004134 propofol Drugs 0.000 abstract 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 abstract 1
- 229960003415 propylparaben Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/789,679 US5990176A (en) | 1997-01-27 | 1997-01-27 | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR011090A1 true AR011090A1 (es) | 2000-08-02 |
Family
ID=25148366
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980100336A AR011090A1 (es) | 1997-01-27 | 1998-01-26 | COMPOSICIONES ANESTÉSICAS DE SEVOFLURANO, METODO PARA SU PREPARACIoN, MÉTODOS PARA INHIBIR SU DEGRADACIoN ANTE LA PRESENCIA DE UN ÁCIDO LEWIS Y UN PROCESO PARA PREPARAR UNA COMPOSICION ANESTÉSICA ESTABLE EN UN CONTENEDOR SELLADO |
| ARP060105042A AR057610A2 (es) | 1997-01-27 | 2006-11-16 | Composiciones anestesicas de sevoflurano, metodo para su preparacion, metodos para inhibir su degradacion ante la presencia de un acido lewis y un proceso para preparar una composicion anestesica estable en un contenedor sellado |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060105042A AR057610A2 (es) | 1997-01-27 | 2006-11-16 | Composiciones anestesicas de sevoflurano, metodo para su preparacion, metodos para inhibir su degradacion ante la presencia de un acido lewis y un proceso para preparar una composicion anestesica estable en un contenedor sellado |
Country Status (27)
| Country | Link |
|---|---|
| US (6) | US5990176A (enExample) |
| EP (2) | EP0967975B1 (enExample) |
| JP (5) | JP3183520B2 (enExample) |
| KR (1) | KR100368672B1 (enExample) |
| CN (3) | CN1152674C (enExample) |
| AR (2) | AR011090A1 (enExample) |
| AT (2) | ATE201987T1 (enExample) |
| AU (1) | AU726733B2 (enExample) |
| BG (2) | BG65414B1 (enExample) |
| BR (1) | BR9806996A (enExample) |
| CA (2) | CA2278133C (enExample) |
| CO (1) | CO4920220A1 (enExample) |
| CZ (1) | CZ297092B6 (enExample) |
| DE (2) | DE69800928T2 (enExample) |
| DK (2) | DK1114641T3 (enExample) |
| ES (2) | ES2256104T3 (enExample) |
| GR (1) | GR3036190T3 (enExample) |
| HU (1) | HUP0002101A3 (enExample) |
| IL (1) | IL130150A (enExample) |
| NO (1) | NO993606L (enExample) |
| NZ (1) | NZ335994A (enExample) |
| PL (1) | PL334477A1 (enExample) |
| PT (2) | PT1114641E (enExample) |
| SK (1) | SK284243B6 (enExample) |
| TR (1) | TR199901579T2 (enExample) |
| WO (1) | WO1998032430A1 (enExample) |
| ZA (1) | ZA98418B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5990176A (en) * | 1997-01-27 | 1999-11-23 | Abbott Laboratories | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid |
| US20030200963A1 (en) * | 1998-01-09 | 2003-10-30 | Flament-Garcia Mary Jane | Container for an inhalation anesthetic |
| US6162443A (en) * | 1998-01-09 | 2000-12-19 | Abbott Laboratories | Container for an inhalation anesthetic |
| US6074668A (en) * | 1998-01-09 | 2000-06-13 | Abbott Laboratories | Container for an inhalation anesthetic |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| ES2211151T3 (es) | 1998-08-19 | 2004-07-01 | Skyepharma Canada Inc. | Dispersiones acuosas inyectables de propofol. |
| EP1439677B9 (en) | 1999-01-08 | 2007-11-07 | Sony Deutschland GmbH | Synchronisation symbol structure for an OFDM system |
| TW523409B (en) | 2000-09-15 | 2003-03-11 | Baxter Int | Container for inhalation anesthetic |
| EP1663186B1 (en) * | 2003-09-10 | 2007-06-20 | Cristália Produtos Químicos Farmacêuticos Ltda. | Stable pharmaceutical composition of fluoroether compound for anesthetic use, method for stabilizing a fluoroether compound, use of stabilizer agent for precluding the degradation of a fluoroether compound |
| BR0303489A (pt) * | 2003-09-10 | 2005-07-05 | Cristalia Prod Quimicos Farm | Composição farmacêutica estabilizada de composto flúor-éter e método para inibir a degradação de composto flúor-éter. uso de agente estabilizante para inibir a degradação de composto flúor éter |
| WO2006113636A2 (en) * | 2005-04-18 | 2006-10-26 | Minrad Inc. | Preparation of sevoflurane with negligible water content |
| WO2009049460A1 (en) * | 2007-10-15 | 2009-04-23 | Jiangsu Hengrui Medicine Co., Ltd. | New packaging material for sevoflurane |
| WO2009094459A1 (en) * | 2008-01-22 | 2009-07-30 | The Board Of Regents Of The University Of Texas System | Volatile anesthetic compositions comprising extractive solvents for regional anesthesia and/or pain relief |
| US20090275785A1 (en) * | 2008-05-01 | 2009-11-05 | Barry Jones | Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process |
| US8563115B2 (en) * | 2008-08-12 | 2013-10-22 | Xerox Corporation | Protective coatings for solid inkjet applications |
| US8092822B2 (en) * | 2008-09-29 | 2012-01-10 | Abbott Cardiovascular Systems Inc. | Coatings including dexamethasone derivatives and analogs and olimus drugs |
| US8283643B2 (en) * | 2008-11-24 | 2012-10-09 | Cymer, Inc. | Systems and methods for drive laser beam delivery in an EUV light source |
| US8191992B2 (en) * | 2008-12-15 | 2012-06-05 | Xerox Corporation | Protective coatings for solid inkjet applications |
| US9278048B2 (en) * | 2009-05-06 | 2016-03-08 | Baxter International, Inc. | Pharmaceutical product and method of use |
| US9102604B1 (en) | 2010-02-15 | 2015-08-11 | Baxter International Inc. | Methods for cleaning distilling columns |
| CN105106182B (zh) * | 2015-09-21 | 2017-12-29 | 山东新时代药业有限公司 | 七氟烷吸入剂 |
| CN105193774B (zh) * | 2015-09-21 | 2018-01-16 | 山东新时代药业有限公司 | 一种七氟烷吸入剂 |
| BE1024432B1 (fr) * | 2016-11-02 | 2018-02-19 | Central Glass Company, Limited | Procédé pour le lavage de récipient de stockage de sévoflurane et procédé pour le stockage de sévoflurane |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2992276A (en) * | 1959-05-20 | 1961-07-11 | Du Pont | Process for preparing polyfluoro alkyl compounds |
| US3527813A (en) * | 1966-10-03 | 1970-09-08 | Air Reduction | 1,1,2 - trifluoro - 2 - chloroethyl difluoromethyl ether and its method of preparation |
| US3689571A (en) * | 1970-07-31 | 1972-09-05 | Baxter Laboratories Inc | Fluorinated ether |
| GB1499818A (en) * | 1974-12-06 | 1978-02-01 | Ici Ltd | Anaesthetic composition |
| US4469898A (en) * | 1979-12-26 | 1984-09-04 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
| US4250334A (en) * | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
| JP2786108B2 (ja) | 1994-03-31 | 1998-08-13 | セントラル硝子株式会社 | フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法 |
| IT1270239B (it) * | 1994-06-17 | 1997-04-29 | Zambon Spa | Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo |
| US5990176A (en) * | 1997-01-27 | 1999-11-23 | Abbott Laboratories | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid |
-
1997
- 1997-01-27 US US08/789,679 patent/US5990176A/en not_active Expired - Lifetime
-
1998
- 1998-01-19 ZA ZA98418A patent/ZA98418B/xx unknown
- 1998-01-23 IL IL13015098A patent/IL130150A/en not_active IP Right Cessation
- 1998-01-23 DE DE69800928T patent/DE69800928T2/de not_active Revoked
- 1998-01-23 AU AU59300/98A patent/AU726733B2/en not_active Expired
- 1998-01-23 PT PT01107733T patent/PT1114641E/pt unknown
- 1998-01-23 CN CNB98802053XA patent/CN1152674C/zh not_active Expired - Lifetime
- 1998-01-23 HU HU0002101A patent/HUP0002101A3/hu unknown
- 1998-01-23 CZ CZ0256199A patent/CZ297092B6/cs not_active IP Right Cessation
- 1998-01-23 DK DK01107733T patent/DK1114641T3/da active
- 1998-01-23 CA CA002278133A patent/CA2278133C/en not_active Expired - Lifetime
- 1998-01-23 DK DK98902707T patent/DK0967975T3/da active
- 1998-01-23 WO PCT/US1998/001376 patent/WO1998032430A1/en not_active Ceased
- 1998-01-23 CO CO98003122A patent/CO4920220A1/es unknown
- 1998-01-23 AT AT98902707T patent/ATE201987T1/de not_active IP Right Cessation
- 1998-01-23 EP EP98902707A patent/EP0967975B1/en not_active Revoked
- 1998-01-23 TR TR1999/01579T patent/TR199901579T2/xx unknown
- 1998-01-23 CN CNB2004100368062A patent/CN1321958C/zh not_active Expired - Lifetime
- 1998-01-23 EP EP01107733A patent/EP1114641B1/en not_active Expired - Lifetime
- 1998-01-23 DE DE69833884T patent/DE69833884T2/de not_active Expired - Lifetime
- 1998-01-23 SK SK861-99A patent/SK284243B6/sk not_active IP Right Cessation
- 1998-01-23 BR BR9806996-9A patent/BR9806996A/pt active IP Right Grant
- 1998-01-23 PL PL98334477A patent/PL334477A1/xx not_active IP Right Cessation
- 1998-01-23 NZ NZ335994A patent/NZ335994A/xx not_active IP Right Cessation
- 1998-01-23 JP JP53216898A patent/JP3183520B2/ja not_active Expired - Lifetime
- 1998-01-23 AT AT01107733T patent/ATE320798T1/de active
- 1998-01-23 PT PT98902707T patent/PT967975E/pt unknown
- 1998-01-23 CN CNA2006101016375A patent/CN1899271A/zh active Pending
- 1998-01-23 ES ES01107733T patent/ES2256104T3/es not_active Expired - Lifetime
- 1998-01-23 ES ES98902707T patent/ES2170474T3/es not_active Expired - Lifetime
- 1998-01-23 KR KR10-1999-7006724A patent/KR100368672B1/ko not_active Ceased
- 1998-01-23 CA CA002626424A patent/CA2626424A1/en not_active Abandoned
- 1998-01-26 AR ARP980100336A patent/AR011090A1/es active IP Right Grant
-
1999
- 1999-07-23 NO NO19993606A patent/NO993606L/no not_active Application Discontinuation
- 1999-08-10 BG BG103656A patent/BG65414B1/bg unknown
- 1999-08-10 BG BG109751A patent/BG109751A/bg unknown
- 1999-11-23 US US09/447,853 patent/US6288127B1/en not_active Expired - Lifetime
-
2000
- 2000-11-16 JP JP2000349024A patent/JP3664648B2/ja not_active Expired - Lifetime
-
2001
- 2001-07-06 GR GR20010401038T patent/GR3036190T3/el not_active IP Right Cessation
- 2001-08-08 US US09/924,573 patent/US6444859B2/en not_active Expired - Lifetime
-
2002
- 2002-07-03 US US10/190,271 patent/US6677492B2/en not_active Expired - Lifetime
-
2003
- 2003-06-26 US US10/606,821 patent/US20040048932A1/en not_active Abandoned
-
2005
- 2005-04-06 JP JP2005109476A patent/JP2005279283A/ja not_active Ceased
- 2005-12-27 JP JP2005374622A patent/JP2006137769A/ja not_active Ceased
- 2005-12-27 JP JP2005374621A patent/JP2006143742A/ja not_active Ceased
-
2006
- 2006-02-27 US US11/362,954 patent/US20060148906A1/en not_active Abandoned
- 2006-11-16 AR ARP060105042A patent/AR057610A2/es unknown
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