AR010341A1 - Constructo de acido nucleico farmacologicamente controlable auto- intensificante, proceso para preparar dicho constructo, vector y celula que locomprenden y uso del mismo y una composicion farmaceutica que comprende el constructo de acido nucleico y un metodo para preparar la composicion - Google Patents
Constructo de acido nucleico farmacologicamente controlable auto- intensificante, proceso para preparar dicho constructo, vector y celula que locomprenden y uso del mismo y una composicion farmaceutica que comprende el constructo de acido nucleico y un metodo para preparar la composicionInfo
- Publication number
- AR010341A1 AR010341A1 ARP970105775A ARP970105775A AR010341A1 AR 010341 A1 AR010341 A1 AR 010341A1 AR P970105775 A ARP970105775 A AR P970105775A AR P970105775 A ARP970105775 A AR P970105775A AR 010341 A1 AR010341 A1 AR 010341A1
- Authority
- AR
- Argentina
- Prior art keywords
- nucleic acid
- construction
- preparing
- pharmaceutical composition
- vector
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
Abstract
Constructo de ácido nucleico que comprende los componentes siguientes: al menos un primer gen estructural que codifica un compuesto activo; al menos unsegundo gen estructural que codifica una proteína de factor de transcripcion; y al menos unasec uencia que se fija a la proteína de factor de transcripcions yal menos una secuencia promotora; en el cual cada secuencia de activacion activa la expresion de un gen estructural y la expresion de la proteína defactor de transcripcion;proceso para preparar dicho constructo, vector y célula que lo comprenden y uso del mismo, y una composicion farmacéutica quecomprende el constructo de ácido nucleico y un método para preparar la composicion farmacéutica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19651443A DE19651443A1 (de) | 1996-12-11 | 1996-12-11 | Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme |
Publications (1)
Publication Number | Publication Date |
---|---|
AR010341A1 true AR010341A1 (es) | 2000-06-07 |
Family
ID=7814335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970105775A AR010341A1 (es) | 1996-12-11 | 1997-12-09 | Constructo de acido nucleico farmacologicamente controlable auto- intensificante, proceso para preparar dicho constructo, vector y celula que locomprenden y uso del mismo y una composicion farmaceutica que comprende el constructo de acido nucleico y un metodo para preparar la composicion |
Country Status (15)
Country | Link |
---|---|
US (3) | US6383785B1 (es) |
EP (1) | EP0848061A3 (es) |
JP (1) | JPH11176A (es) |
KR (1) | KR19980064289A (es) |
CN (1) | CN1191898A (es) |
AR (1) | AR010341A1 (es) |
AU (1) | AU738344B2 (es) |
BR (1) | BR9705527A (es) |
CA (1) | CA2224334A1 (es) |
CZ (1) | CZ397797A3 (es) |
DE (1) | DE19651443A1 (es) |
HU (1) | HUP9702377A3 (es) |
PL (1) | PL323657A1 (es) |
RU (1) | RU2197993C2 (es) |
TR (1) | TR199701579A2 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6319503B1 (en) | 1998-02-19 | 2001-11-20 | Proteinix Company | Heat shock fusion-based vaccine system |
CZ121599A3 (cs) | 1998-04-09 | 1999-10-13 | Aventis Pharma Deutschland Gmbh | Jednořetězcová molekula vázající několik antigenů, způsob její přípravy a léčivo obsahující tuto molekulu |
DE19831420A1 (de) * | 1998-07-14 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | Expressionssysteme enthaltend chimäre Promotoren mit Bindungsstellen für rekombinante Transkriptionsfaktoren |
WO2000005393A2 (en) | 1998-07-21 | 2000-02-03 | Cobra Therapeutics Limited | A polynucleotide comprising a ubiquitous chromatin opening element (ucoe) |
AU6636800A (en) * | 1999-08-13 | 2001-03-13 | Proteinix Company | Heat shock fusion-based vaccine system |
IL132446A0 (en) * | 1999-10-18 | 2001-03-19 | Genena Ltd | A method for establishing connections between genes |
FR2801319A1 (fr) * | 1999-11-18 | 2001-05-25 | Inst Nat Sante Rech Med | Construction d'acide nucleique porteuse d'un systeme regulant l'expression d'un gene |
AU2046801A (en) * | 1999-11-23 | 2001-06-04 | Mayo Foundation For Medical Education And Research | Gene expression by positive feedback activation of a cell type-specific promoter |
US7829084B2 (en) | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
ES2601141T3 (es) | 2001-09-13 | 2017-02-14 | California Institute Of Technology | Método para la expresión de moléculas de ARN pequeño dentro de una célula |
US7737124B2 (en) | 2001-09-13 | 2010-06-15 | California Institute Of Technology | Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell |
JP2005253385A (ja) * | 2004-03-12 | 2005-09-22 | Shin Sasaki | 転写因子結合領域導入プロモータを含む発現ベクター及び転写因子重発現システムによる遺伝子発現方法 |
RS54088B1 (en) | 2005-07-25 | 2015-10-30 | Emergent Products Development Seattle Llc | B-CELL REDUCTION BY USING CD37-SPECIFIC AND CD20-SPECIFIC BINDING MOLECULES |
KR101571027B1 (ko) | 2006-06-12 | 2015-11-23 | 이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 | 효과기 기능을 갖는 단일쇄 다가 결합 단백질 |
EP2167130A2 (en) * | 2007-07-06 | 2010-03-31 | Trubion Pharmaceuticals, Inc. | Binding peptides having a c-terminally disposed specific binding domain |
NZ588671A (en) * | 2008-04-11 | 2012-11-30 | Emergent Product Dev Seattle | Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof |
CA2744289A1 (en) * | 2008-11-25 | 2010-06-03 | Otsuka Pharmaceutical Co., Ltd. | Stem cell for therapeutic use which is derived from human monocyte, and method for inducing same |
WO2012089231A1 (en) * | 2010-12-30 | 2012-07-05 | Okairòs Ag | Paramyxovirus vaccines |
CN109535259A (zh) * | 2012-12-05 | 2019-03-29 | 生控基因疫苗股份有限公司 | 用作诱发抗原特异性t细胞反应的免疫原性增强剂的融合蛋白 |
WO2014127148A1 (en) * | 2013-02-14 | 2014-08-21 | The J. David Gladstone Institutes | Compositions and methods of use thereof for identifying anti-viral agents |
JP2016519570A (ja) | 2013-03-14 | 2016-07-07 | エペイウス バイオテクノロジーズ コーポレイション | 改善されたチミジンキナーゼ遺伝子 |
WO2016048994A2 (en) * | 2014-09-23 | 2016-03-31 | President And Fellows Of Harvard College | Systems and methods of cell-free protein synthesis in droplets and other compartments |
CA2999138C (en) | 2015-09-21 | 2024-05-21 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU683227B2 (en) * | 1992-08-26 | 1997-11-06 | Bioscience 2002 Llc | Tetracycline repressor-mediated binary regulation system for control of gene expression in transgenic animals |
US5589362A (en) * | 1993-06-14 | 1996-12-31 | Basf Aktiengesellschaft | Tetracycline regulated transcriptional modulators with altered DNA binding specificities |
US5464758A (en) * | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
ES2140359T1 (es) * | 1993-06-14 | 2000-03-01 | Basf Ag | Control preciso de expresion genetica en celulas eucarioticas mediante promotores que responden a la tetaciclina. |
GB9506466D0 (en) | 1994-08-26 | 1995-05-17 | Prolifix Ltd | Cell cycle regulated repressor and dna element |
WO1996006938A1 (de) * | 1994-08-26 | 1996-03-07 | Hoechst Aktiengesellschaft | Gentherapeutische behandlung von gefässerkrankungen durch einen zellspezifischen, zellzyklusabhängigen wirkstoff |
DE19524720A1 (de) | 1995-07-12 | 1997-01-16 | Hoechst Ag | Zellspezifische Gentherapie mit Hilfe eines neuen Promotors für den "Tissue Inhibitor of Metalloproteinasn-3" |
DE19605274A1 (de) | 1996-02-13 | 1997-08-14 | Hoechst Ag | Nukleinsäurekonstrukte für die zellzyklusregulierte Expression von Genen, derartige Konstrukte enthaltende Zellen sowie deren Verwendung zur Herstellung von Heilmitteln |
DE19605279A1 (de) | 1996-02-13 | 1997-08-14 | Hoechst Ag | Zielzellspezifische Vektoren für die Einschleusung von Genen in Zellen, Arzneimittel enthaltend derartige Vektoren und deren Verwendung |
-
1996
- 1996-12-11 DE DE19651443A patent/DE19651443A1/de not_active Withdrawn
-
1997
- 1997-12-09 CZ CZ973977A patent/CZ397797A3/cs unknown
- 1997-12-09 TR TR97/01579A patent/TR199701579A2/xx unknown
- 1997-12-09 HU HU9702377A patent/HUP9702377A3/hu unknown
- 1997-12-09 US US08/987,348 patent/US6383785B1/en not_active Expired - Fee Related
- 1997-12-09 AR ARP970105775A patent/AR010341A1/es not_active Application Discontinuation
- 1997-12-10 RU RU97120927/14A patent/RU2197993C2/ru not_active IP Right Cessation
- 1997-12-10 EP EP97121752A patent/EP0848061A3/en not_active Withdrawn
- 1997-12-10 AU AU48362/97A patent/AU738344B2/en not_active Ceased
- 1997-12-10 CA CA002224334A patent/CA2224334A1/en not_active Abandoned
- 1997-12-10 CN CN97120870A patent/CN1191898A/zh active Pending
- 1997-12-11 PL PL97323657A patent/PL323657A1/xx unknown
- 1997-12-11 JP JP9341728A patent/JPH11176A/ja active Pending
- 1997-12-11 KR KR1019970070183A patent/KR19980064289A/ko not_active Application Discontinuation
- 1997-12-11 BR BR9705527-1A patent/BR9705527A/pt not_active Application Discontinuation
-
2002
- 2002-04-04 US US10/115,095 patent/US6482618B2/en not_active Expired - Fee Related
- 2002-06-14 US US10/170,567 patent/US20030008398A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2224334A1 (en) | 1998-06-11 |
EP0848061A3 (en) | 2004-02-18 |
CN1191898A (zh) | 1998-09-02 |
AU738344B2 (en) | 2001-09-13 |
US20020151049A1 (en) | 2002-10-17 |
EP0848061A2 (en) | 1998-06-17 |
TR199701579A3 (tr) | 1998-06-22 |
TR199701579A2 (xx) | 1998-06-22 |
DE19651443A1 (de) | 1998-06-18 |
RU2197993C2 (ru) | 2003-02-10 |
HUP9702377A2 (hu) | 1998-09-28 |
KR19980064289A (ko) | 1998-10-07 |
AU4836297A (en) | 1998-06-18 |
CZ397797A3 (cs) | 1998-06-17 |
PL323657A1 (en) | 1998-06-22 |
US20030008398A1 (en) | 2003-01-09 |
JPH11176A (ja) | 1999-01-06 |
US6383785B1 (en) | 2002-05-07 |
HU9702377D0 (en) | 1998-03-02 |
HUP9702377A3 (en) | 2004-06-28 |
BR9705527A (pt) | 1999-10-05 |
US6482618B2 (en) | 2002-11-19 |
MX9710007A (es) | 1998-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR010341A1 (es) | Constructo de acido nucleico farmacologicamente controlable auto- intensificante, proceso para preparar dicho constructo, vector y celula que locomprenden y uso del mismo y una composicion farmaceutica que comprende el constructo de acido nucleico y un metodo para preparar la composicion | |
STAVNEZER et al. | Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system | |
AR024699A1 (es) | Polipeptidos hibridos con propiedades farmacocineticas aumentadas | |
DE69730218D1 (de) | Fusogene liposomen | |
TR199802789T2 (xx) | Eksendin analoglar� bunlar�n �retimi i�in y�ntemler ve bunlar� i�eren farmas�tik m�stahzarlar. | |
AR007737A1 (es) | Un derivado de un peptido soluble, un procedimiento para su preparacion, una porcion polipeptidica del mismo, un polimero de adn, un vector de expresionreplicable, una celula huesped, un elemento peptidico modificado que se une a la membrana, una composicion farmaceutica que comprende dicho derivado y el uso | |
PT695360E (pt) | Adenovirus recombinantes deficientes, para a terapia genica de tumores | |
DK0912176T3 (da) | Anvendelse af pyridylalkan-, pyridylalken- og/eller pyridylalkynsyreamider til behandling af tumorer eller immunosuppression | |
BR112022016657A2 (pt) | Células car-t bcma com atividades melhoradas | |
DE69635895D1 (de) | Antigen presentierende bläschen, die von zellen ableiten | |
ATE368054T1 (de) | Verbindungen und methoden zur modulierung von occludin-abhängiger gewebepermeabilität | |
CY1109439T1 (el) | Αναλογα γλυκοπρωτεϊνικων ορμονων δισουλφιδικης σταυρωτης συνδεσης, η παρασκευη και η χρηση τους | |
ATE345682T1 (de) | In vitro verfahren zum einbringen von nukleinsäuren in eine zelle | |
BRPI0620806B8 (pt) | complexo e composição compreendendo um peptídeo e uma molécula carga, e uso da referida composição | |
DE69942459D1 (de) | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung | |
AR033834A1 (es) | Una proteina de fusion para liberar un compuesto a una celula, un metodo para liberar dicho compuesto, un metodo para identificar un peptido penetrador de membranas, y el uso de una proteina de fusion para la manufactura de un agente | |
DE69834824D1 (de) | Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert | |
DE69837754D1 (de) | Kombinierte tumor suppressor-gen-therapie und chemotherapie bei der neoplasmabehandlung | |
Weisdorf | The role of second transplants for leukemia | |
BR0015236A (pt) | Métodos de inicialização para sistemas catalisadores múltiplos | |
Takagi et al. | Evidence for exclusive biosynthesis in vivo of serum albumin by bound polysomes of rat liver | |
BR112023007922A2 (pt) | Método de geração de linfócitos infiltrantes no tumor, método para expandir uma população de linfócitos infiltrantes no tumor (tils) ou linfócitos infiltrantes na medula (mils) e métodos de tratamento de câncer em um sujeito | |
PT894141E (pt) | Proteinas hibridas que formam heterodimeros | |
BR9811850A (pt) | Expressão recombinante de peptìdeo c de insulina | |
DK1007717T3 (da) | Metoder og sammensætninger til cancerterapi under anvendelse af gener, der koder for interferon-beta |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |