AR009968A1 - Metodo para tratar infecciones virales en mamiferos de sangre caliente - Google Patents

Metodo para tratar infecciones virales en mamiferos de sangre caliente

Info

Publication number
AR009968A1
AR009968A1 ARP970104697A ARP970104697A AR009968A1 AR 009968 A1 AR009968 A1 AR 009968A1 AR P970104697 A ARP970104697 A AR P970104697A AR P970104697 A ARP970104697 A AR P970104697A AR 009968 A1 AR009968 A1 AR 009968A1
Authority
AR
Argentina
Prior art keywords
cancer
cell
fungicide
virus
treatment
Prior art date
Application number
ARP970104697A
Other languages
English (en)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of AR009968A1 publication Critical patent/AR009968A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Método para tratar el HIV u otras infecciones virosicas, mediante el suministro de un herbicida o de un fungicida, o derivados de ellos, a animaleso seres humanos. Los fungicidas o herbicidas se pueden usar junto con otros tratamientos como, por ejemplo, AZT o los inhibidores de proteasa, para eltratamiento del HIV. Por ejemplo, el tiabendazol y el cloroprofam han demostrado reducir con rapidez el nivel de produccion de virus, en poblacionescelulares cronicamente infectadascon HIV-1, y el efecto virosico se mantiene con la exposicion continuada del compuesto. Esta reduccion de la produccion devirus tiene lugar en concentraciones que no son toxicas para la célula hospedante y que no ejercen efecto sobre la síntesis de ADN, ARN y proteínascelulares. Además las células cronicamente infectadas que se trato, durante lapsos prolongados, con tiabendazol y cloroprofam no estaban infectadas conHIV. También se da a conocer un método para inhibir el crecimiento de tumores y cánceres en mamíferos, que comprende el suministro del derivado de unherbicida o un fungicida. Los fungicidas o herbicidas se pueden emplear junto con otros tratamientos como, por ejemplo, taxol para el tratamiento de cáncerde pecho. En la composicion herbicida o fungicida también se puede incluir potenciadores. Este método es particularmente efectivo cuando el cáncer o elvirus es una célula animal genéticamente modificada por material genético vegetal o fungico. También se puede suministrar primero un agentequimioterapéutico, para reducir de manera importante el tamano del cáncer, y después se emplea el tratamiento con el herbicida o el fungicida. Estos métodosadquieren particular eficacia cuando el cáncero el virus es una céula mutada que comprende material genético vegetal o fungico
ARP970104697A 1997-05-16 1997-10-10 Metodo para tratar infecciones virales en mamiferos de sangre caliente AR009968A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4672697P 1997-05-16 1997-05-16

Publications (1)

Publication Number Publication Date
AR009968A1 true AR009968A1 (es) 2000-05-17

Family

ID=21945046

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970104697A AR009968A1 (es) 1997-05-16 1997-10-10 Metodo para tratar infecciones virales en mamiferos de sangre caliente

Country Status (19)

Country Link
EP (1) EP0954309A1 (es)
JP (1) JP2000510156A (es)
KR (1) KR20000049064A (es)
CN (1) CN1254281A (es)
AR (1) AR009968A1 (es)
AU (1) AU7402998A (es)
BR (1) BR9712981A (es)
CA (1) CA2268848A1 (es)
CO (1) CO5070657A1 (es)
CZ (1) CZ124999A3 (es)
HU (1) HUP9904092A3 (es)
IL (1) IL129351A0 (es)
NO (1) NO991701L (es)
PE (1) PE11499A1 (es)
PL (1) PL335160A1 (es)
SK (1) SK46999A3 (es)
TR (1) TR199901530T2 (es)
WO (1) WO1998051303A1 (es)
ZA (1) ZA979095B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177460B1 (en) 1995-04-12 2001-01-23 The Procter & Gamble Company Method of treatment for cancer or viral infections
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US6686391B2 (en) 1995-08-04 2004-02-03 University Of Arizona Foundation N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
JP2002537327A (ja) * 1999-02-26 2002-11-05 ナプロ バイオセラピューティクス,インコーポレイテッド 前立腺癌の治療レジメ
CA2366697A1 (en) * 1999-02-26 2000-08-31 Larry Helson Treatment regimen for hormone-sensitive cancers
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
AU2001286744A1 (en) * 2000-08-25 2002-03-04 Beth Israel Deaconess Medical Center Compounds and methods for inhibiting neuronal cell death
US6407105B1 (en) * 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6462062B1 (en) 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6608096B1 (en) 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
EP1330441A2 (en) * 2000-09-26 2003-07-30 The University of Arizona Foundation Benzimidazoles and methods for use thereof in the treatment of cancer or viral infections
AU2002239395A1 (en) * 2000-11-01 2002-06-03 The Procter And Gamble Company Hiv treatment with benzimidazoles
JP2004115397A (ja) * 2002-09-25 2004-04-15 Fuji Photo Film Co Ltd 血管疾患治療薬を含むリポソーム
AU2005313839B2 (en) * 2004-12-06 2010-03-11 Pitney Pharmaceuticals Pty Limited Treatment for cancer
PT1830847E (pt) 2004-12-06 2015-02-05 Pitney Pharmaceuticals Pty Ltd Tratamento para o cancro
US7727967B2 (en) * 2006-02-24 2010-06-01 Boise State University Cyanooxime inhibitors of carbonyl reductase and methods of using said inhibitors in treatments involving anthracyclines
WO2009043093A1 (en) * 2007-10-04 2009-04-09 Newsouth Innovations Pty Limited Hif inhibition
CN101643729B (zh) * 2008-08-07 2011-12-28 复旦大学 核酸分子nrn1sr22及其在制备抗癌药物中的应用
EP3119768B1 (en) 2014-03-16 2019-07-31 Hadasit Medical Research Services And Development Ltd. 3,4-bromo or -sulfonate substituted 1h-pyrrole-2,5-dione derivatives as type iii deiodinase (dio3) inhibitors for treating depressions and cancer
CN105418711A (zh) * 2015-11-06 2016-03-23 山东大学 一种α-L-鼠李糖苷酶在制备羟基脲糖苷衍生物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9420017B (sl) * 1993-03-31 2003-12-31 Merck & Co. Inc. Inhibitorji proteaze hiv-a v farmacevtskih kombinacijah za zdravljenje aids-a
US5665713A (en) * 1995-04-12 1997-09-09 Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US5656615A (en) * 1995-04-12 1997-08-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals
TR199701151T1 (xx) * 1995-04-12 1998-03-21 The Procter & Gamble Company Vir�sler ve kanserlerin geli�mesini �nlemeye mahsus, N-klorofenil karbamatlar� ve N-klorofeniltiokarbamatlar� i�eren bir farmas�tik bile�im.
HUP9903420A3 (en) * 1995-08-04 2001-12-28 Procter & Gamble Use of fluconazole for the preparation of pharmaceutical compositions, inhibiting the growth of cancers and treating viral infections

Also Published As

Publication number Publication date
HUP9904092A3 (en) 2000-07-28
BR9712981A (pt) 2000-04-18
TR199901530T2 (xx) 1999-10-21
NO991701D0 (no) 1999-04-09
WO1998051303A1 (en) 1998-11-19
PL335160A1 (en) 2000-04-10
CN1254281A (zh) 2000-05-24
CO5070657A1 (es) 2001-08-28
ZA979095B (en) 1998-05-11
EP0954309A1 (en) 1999-11-10
PE11499A1 (es) 1999-03-01
CZ124999A3 (cs) 1999-09-15
AU7402998A (en) 1998-12-08
JP2000510156A (ja) 2000-08-08
IL129351A0 (en) 2000-02-17
NO991701L (no) 2000-01-17
HUP9904092A2 (hu) 2000-04-28
CA2268848A1 (en) 1998-11-19
SK46999A3 (en) 2000-05-16
KR20000049064A (ko) 2000-07-25

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