AR009968A1 - METHOD FOR TREATING VIRAL INFECTIONS IN MAMMALS OF HOT BLOOD - Google Patents
METHOD FOR TREATING VIRAL INFECTIONS IN MAMMALS OF HOT BLOODInfo
- Publication number
- AR009968A1 AR009968A1 ARP970104697A ARP970104697A AR009968A1 AR 009968 A1 AR009968 A1 AR 009968A1 AR P970104697 A ARP970104697 A AR P970104697A AR P970104697 A ARP970104697 A AR P970104697A AR 009968 A1 AR009968 A1 AR 009968A1
- Authority
- AR
- Argentina
- Prior art keywords
- cancer
- cell
- fungicide
- virus
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Método para tratar el HIV u otras infecciones virosicas, mediante el suministro de un herbicida o de un fungicida, o derivados de ellos, a animaleso seres humanos. Los fungicidas o herbicidas se pueden usar junto con otros tratamientos como, por ejemplo, AZT o los inhibidores de proteasa, para eltratamiento del HIV. Por ejemplo, el tiabendazol y el cloroprofam han demostrado reducir con rapidez el nivel de produccion de virus, en poblacionescelulares cronicamente infectadascon HIV-1, y el efecto virosico se mantiene con la exposicion continuada del compuesto. Esta reduccion de la produccion devirus tiene lugar en concentraciones que no son toxicas para la célula hospedante y que no ejercen efecto sobre la síntesis de ADN, ARN y proteínascelulares. Además las células cronicamente infectadas que se trato, durante lapsos prolongados, con tiabendazol y cloroprofam no estaban infectadas conHIV. También se da a conocer un método para inhibir el crecimiento de tumores y cánceres en mamíferos, que comprende el suministro del derivado de unherbicida o un fungicida. Los fungicidas o herbicidas se pueden emplear junto con otros tratamientos como, por ejemplo, taxol para el tratamiento de cáncerde pecho. En la composicion herbicida o fungicida también se puede incluir potenciadores. Este método es particularmente efectivo cuando el cáncer o elvirus es una célula animal genéticamente modificada por material genético vegetal o fungico. También se puede suministrar primero un agentequimioterapéutico, para reducir de manera importante el tamano del cáncer, y después se emplea el tratamiento con el herbicida o el fungicida. Estos métodosadquieren particular eficacia cuando el cáncero el virus es una céula mutada que comprende material genético vegetal o fungicoMethod of treating HIV or other viral infections, by supplying, or derivatives of, a herbicide or fungicide to animals or humans. Fungicides or herbicides can be used in conjunction with other treatments, such as AZT or protease inhibitors, for the treatment of HIV. For example, thiabendazole and chloroprofam have been shown to rapidly reduce the level of virus production in cell populations chronically infected with HIV-1, and the virosic effect is maintained with continued exposure of the compound. This reduction in virus production occurs at concentrations that are not toxic to the host cell and have no effect on the synthesis of DNA, RNA, and cell proteins. Furthermore, the chronically infected cells that were treated, for prolonged periods, with thiabendazole and chloroprofam were not infected with IVH. Also disclosed is a method of inhibiting the growth of tumors and cancers in mammals, comprising supplying the derivative of a unherbicide or a fungicide. Fungicides or herbicides can be used together with other treatments such as taxol for the treatment of breast cancer. Enhancers may also be included in the herbicidal or fungicidal composition. This method is particularly effective when the cancer or virus is an animal cell genetically modified by plant or fungal genetic material. A chemotherapeutic agent may also be given first, to significantly reduce the size of the cancer, and then treatment with the herbicide or fungicide is employed. These methods are particularly effective when the cancer virus is a mutated cell that includes plant or fungal genetic material.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4672697P | 1997-05-16 | 1997-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR009968A1 true AR009968A1 (en) | 2000-05-17 |
Family
ID=21945046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970104697A AR009968A1 (en) | 1997-05-16 | 1997-10-10 | METHOD FOR TREATING VIRAL INFECTIONS IN MAMMALS OF HOT BLOOD |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0954309A1 (en) |
| JP (1) | JP2000510156A (en) |
| KR (1) | KR20000049064A (en) |
| CN (1) | CN1254281A (en) |
| AR (1) | AR009968A1 (en) |
| AU (1) | AU7402998A (en) |
| BR (1) | BR9712981A (en) |
| CA (1) | CA2268848A1 (en) |
| CO (1) | CO5070657A1 (en) |
| CZ (1) | CZ124999A3 (en) |
| HU (1) | HUP9904092A3 (en) |
| IL (1) | IL129351A0 (en) |
| NO (1) | NO991701L (en) |
| PE (1) | PE11499A1 (en) |
| PL (1) | PL335160A1 (en) |
| SK (1) | SK46999A3 (en) |
| TR (1) | TR199901530T2 (en) |
| WO (1) | WO1998051303A1 (en) |
| ZA (1) | ZA979095B (en) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
| US6177460B1 (en) | 1995-04-12 | 2001-01-23 | The Procter & Gamble Company | Method of treatment for cancer or viral infections |
| US6262093B1 (en) | 1995-04-12 | 2001-07-17 | The Proctor & Gamble Company | Methods of treating cancer with benzimidazoles |
| US6265427B1 (en) | 1995-06-07 | 2001-07-24 | The Proctor & Gamble Company | Pharmaceutical composition for the method of treating leukemia |
| US5770616A (en) | 1995-06-07 | 1998-06-23 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
| US6686391B2 (en) | 1995-08-04 | 2004-02-03 | University Of Arizona Foundation | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions |
| US5900429A (en) | 1997-01-28 | 1999-05-04 | The Procter & Gamble Company | Method for inhibiting the growth of cancers |
| US6506783B1 (en) | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
| US6245789B1 (en) * | 1998-05-19 | 2001-06-12 | The Procter & Gamble Company | HIV and viral treatment |
| WO2000050021A2 (en) * | 1999-02-26 | 2000-08-31 | Napro Biotherapeutics, Inc. | Treatment regimen for prostate cancer, initiated after androgen ablative therapy has started |
| JP2002537328A (en) * | 1999-02-26 | 2002-11-05 | ナプロ バイオセラピューティクス，インコーポレイテッド | Treatment regimen for hormone-sensitive cancer |
| US6423734B1 (en) | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
| AU2001286744A1 (en) * | 2000-08-25 | 2002-03-04 | Beth Israel Deaconess Medical Center | Compounds and methods for inhibiting neuronal cell death |
| US6608096B1 (en) | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| AU9279601A (en) * | 2000-09-26 | 2002-04-08 | Procter & Gamble | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6380232B1 (en) | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
| US6407105B1 (en) * | 2000-09-26 | 2002-06-18 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6462062B1 (en) | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| WO2002041891A2 (en) * | 2000-11-01 | 2002-05-30 | The Procter & Gamble Company | Hiv treatment with benzimidazoles |
| JP2004115397A (en) * | 2002-09-25 | 2004-04-15 | Fuji Photo Film Co Ltd | Liposome comprising therapeutic agent for vascular disease |
| WO2006060853A1 (en) * | 2004-12-06 | 2006-06-15 | Newsouth Innovations Pty Limited | Treatment for cancer |
| AU2005313839B2 (en) * | 2004-12-06 | 2010-03-11 | Pitney Pharmaceuticals Pty Limited | Treatment for cancer |
| US7727967B2 (en) * | 2006-02-24 | 2010-06-01 | Boise State University | Cyanooxime inhibitors of carbonyl reductase and methods of using said inhibitors in treatments involving anthracyclines |
| WO2009043093A1 (en) * | 2007-10-04 | 2009-04-09 | Newsouth Innovations Pty Limited | Hif inhibition |
| CN101643729B (en) * | 2008-08-07 | 2011-12-28 | 复旦大学 | Nucleic acid molecule NRN1SR22 and application thereof in preparation of anticancer medicaments |
| US10435365B2 (en) | 2014-03-16 | 2019-10-08 | Hadasit Medical Research Services And Development Ltd. | Type III deiodinase inhibitors and uses thereof |
| CN105418711A (en) * | 2015-11-06 | 2016-03-23 | 山东大学 | Application of alpha-L-rhamnosidase to preparing hydroxycarbamide and glycoside derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090186C (en) * | 1993-03-31 | 2002-09-04 | 麦克公司 | HIV protease inhibitors in pharmaceutical combinations for the treatment of AIDS |
| US5656615A (en) * | 1995-04-12 | 1997-08-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals |
| US5665713A (en) * | 1995-04-12 | 1997-09-09 | Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
| TR199701151T1 (en) * | 1995-04-12 | 1998-03-21 | The Procter & Gamble Company | A pharmaceutical composition containing N-chlorophenyl carbamates and N-chlorophenylthiocarbamates, for inhibiting the development of viruses and cancers. |
| NZ503921A (en) * | 1995-08-04 | 2002-03-01 | Procter & Gamble | Use of fluconazole mixed with chemotherapeutic agents for inhibiting the growth of cancers or tumors |
-
1997
- 1997-10-09 PE PE1997000894A patent/PE11499A1/en not_active Application Discontinuation
- 1997-10-10 ZA ZA9709095A patent/ZA979095B/en unknown
- 1997-10-10 AR ARP970104697A patent/AR009968A1/en unknown
- 1997-11-07 CO CO97065469A patent/CO5070657A1/en unknown
- 1997-11-26 JP JP10522997A patent/JP2000510156A/en active Pending
- 1997-11-26 CZ CZ991249A patent/CZ124999A3/en unknown
- 1997-11-26 CN CN97182189A patent/CN1254281A/en active Pending
- 1997-11-26 TR TR1999/01530T patent/TR199901530T2/en unknown
- 1997-11-26 KR KR1019990703137A patent/KR20000049064A/en not_active Application Discontinuation
- 1997-11-26 WO PCT/US1997/021564 patent/WO1998051303A1/en not_active Application Discontinuation
- 1997-11-26 AU AU74029/98A patent/AU7402998A/en not_active Abandoned
- 1997-11-26 IL IL12935197A patent/IL129351A0/en unknown
- 1997-11-26 CA CA002268848A patent/CA2268848A1/en not_active Abandoned
- 1997-11-26 PL PL97335160A patent/PL335160A1/en unknown
- 1997-11-26 SK SK469-99A patent/SK46999A3/en unknown
- 1997-11-26 HU HU9904092A patent/HUP9904092A3/en unknown
- 1997-11-26 EP EP97949599A patent/EP0954309A1/en not_active Withdrawn
- 1997-11-26 BR BR9712981-0A patent/BR9712981A/en unknown
-
1999
- 1999-04-09 NO NO991701A patent/NO991701L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SK46999A3 (en) | 2000-05-16 |
| BR9712981A (en) | 2000-04-18 |
| IL129351A0 (en) | 2000-02-17 |
| JP2000510156A (en) | 2000-08-08 |
| EP0954309A1 (en) | 1999-11-10 |
| CZ124999A3 (en) | 1999-09-15 |
| PE11499A1 (en) | 1999-03-01 |
| HUP9904092A2 (en) | 2000-04-28 |
| ZA979095B (en) | 1998-05-11 |
| WO1998051303A1 (en) | 1998-11-19 |
| NO991701L (en) | 2000-01-17 |
| CA2268848A1 (en) | 1998-11-19 |
| CO5070657A1 (en) | 2001-08-28 |
| PL335160A1 (en) | 2000-04-10 |
| KR20000049064A (en) | 2000-07-25 |
| NO991701D0 (en) | 1999-04-09 |
| CN1254281A (en) | 2000-05-24 |
| HUP9904092A3 (en) | 2000-07-28 |
| AU7402998A (en) | 1998-12-08 |
| TR199901530T2 (en) | 1999-10-21 |
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