AR005808A1 - Un peptido, usos del mismo, un proceso para prepararlo y una composicion farmaceutica que lo comprende - Google Patents
Un peptido, usos del mismo, un proceso para prepararlo y una composicion farmaceutica que lo comprendeInfo
- Publication number
- AR005808A1 AR005808A1 ARP970100572A ARP970100572A AR005808A1 AR 005808 A1 AR005808 A1 AR 005808A1 AR P970100572 A ARP970100572 A AR P970100572A AR P970100572 A ARP970100572 A AR P970100572A AR 005808 A1 AR005808 A1 AR 005808A1
- Authority
- AR
- Argentina
- Prior art keywords
- peptide
- lower alkyl
- amino acid
- peptides
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se refiere a péptidos con la fórmula (I), en donde Y es hidrógeno, R-C(=O) NH- en donde R es hidrógeno, un alquilo más bajo, o un alquilo de cadena larga,siendo el grupo alquilo lineal, ramificado o cíclico, residuo péptido o aminoácido consustitución N, o residuo polipéptido o residuo polipéptido queincluye una mitad péptida o aminoácida con N sustituciones; x es -OPO3H2, o un derivado funcional del mismo; A es un alquilo más bajo, B es H- o un alquilomás bajo, B es H- o un alquilom ás bajo; Z es H, -COOH, -CONHR1, - COR1; en donde R1=H, -NH2, -NHR3 en el que R3 es un alquilo más bajo o un aminoácidoo dipéptido en la forma carboxílica o amidada; o una sal del mismo farmacológicamente aceptable; a un procesopara preparar péptidos, quecomprende la sintetización química de un péptido de la fórmula (I) a partir de los aminoácidos simples y/o peptídicos preformados de dos o más residuos deaminoácidos; a una composición farmacéutica que comprende uncatalizador o diluyente fisiológicamente aceptable y, como ingrediente activo uno de dichospéptidos, y a un uso de dichos péptidos en la fabricación de un medicamento para ser empleado en el tratamiento de las enfermedades neoplásticas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9603227.1A GB9603227D0 (en) | 1996-02-15 | 1996-02-15 | Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR005808A1 true AR005808A1 (es) | 1999-07-14 |
Family
ID=10788833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970100572A AR005808A1 (es) | 1996-02-15 | 1997-02-13 | Un peptido, usos del mismo, un proceso para prepararlo y una composicion farmaceutica que lo comprende |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6245742B1 (es) |
| EP (1) | EP0821696B1 (es) |
| JP (1) | JPH11504658A (es) |
| KR (1) | KR19990007783A (es) |
| CN (1) | CN1185785A (es) |
| AR (1) | AR005808A1 (es) |
| AT (1) | ATE266041T1 (es) |
| AU (1) | AU1768297A (es) |
| BR (1) | BR9702084A (es) |
| CA (1) | CA2218378A1 (es) |
| DE (1) | DE69728938D1 (es) |
| EA (1) | EA199700318A1 (es) |
| GB (1) | GB9603227D0 (es) |
| HU (1) | HUP9900661A3 (es) |
| IL (1) | IL121853A0 (es) |
| MX (1) | MX9707771A (es) |
| NO (1) | NO974750L (es) |
| NZ (1) | NZ328895A (es) |
| PL (1) | PL322779A1 (es) |
| WO (1) | WO1997030079A1 (es) |
| ZA (1) | ZA971171B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020055463A1 (en) * | 1998-12-24 | 2002-05-09 | Christiane Garbay | Pseudopeptide compounds having an inhibiting activity with respect to paths activated by proteins with active tyrosine kinase activity and pharmaceutical compositions containing same |
| FR2787793B1 (fr) * | 1998-12-24 | 2001-03-23 | Inst Nat Sante Rech Med | Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant |
| FR2793796A1 (fr) * | 1999-04-14 | 2000-11-24 | Hoechst Marion Roussel Inc | Nouveaux derives d'imidazoles, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
| FR2796381A1 (fr) * | 1999-07-12 | 2001-01-19 | Hoechst Marion Roussel Inc | Derives bicycliques de thioazepine ou de caprolactame, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
| US20040191926A1 (en) * | 2001-09-26 | 2004-09-30 | Zhong-Yin Zhang | Ptp1b inhibitors and ligands |
| WO2005114197A2 (en) * | 2004-04-15 | 2005-12-01 | Albert Einstein College Of Medicine Of Yeshiva University | Activity-based probes for protein tyrosine phosphatases |
| CN101652660B (zh) | 2007-02-26 | 2017-09-01 | 干细胞技术公司 | 减小液体培养基的弯月面曲率的方法 |
| CA2678570C (en) | 2008-09-12 | 2016-08-16 | Stemcell Technologies Inc. | Cell culture vessels for meniscus reduction with aqueous solutions |
| CN103387602B (zh) * | 2012-05-09 | 2018-07-06 | 中国科学院上海药物研究所 | 一种新型开链四肽类似物及其制备方法和用途 |
| WO2014107811A1 (en) | 2013-01-10 | 2014-07-17 | Stemcell Technologies Inc. | Meniscus reducing member |
| US10537891B2 (en) | 2013-01-10 | 2020-01-21 | Stemcell Technologies Inc. | Meniscus reducing member |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5801149A (en) * | 1991-06-19 | 1998-09-01 | Joslin D-Abetes Center, Inc. | Inhibition of signal transduction molecules |
| US5739278A (en) * | 1993-05-10 | 1998-04-14 | University Of Washington | Compositions for protein tyrosine phosphatases |
| JP3585044B2 (ja) | 1993-06-30 | 2004-11-04 | フアルマシア・エ・アツプジヨン・エツセ・ピー・アー | 細胞分裂促進及び細胞運動促進のペプチド阻害剤 |
| WO1996023813A1 (en) * | 1995-02-01 | 1996-08-08 | Affymax Technologies N.V. | Peptides and compounds that bind to sh2 domains |
| GB9517060D0 (en) * | 1995-08-17 | 1995-10-25 | Ciba Geigy Ag | Acylated oligopeptide derivatives |
| GB9516842D0 (en) * | 1995-08-17 | 1995-10-18 | Ciba Geigy Ag | Various acylated oligopeptides |
-
1996
- 1996-02-15 GB GBGB9603227.1A patent/GB9603227D0/en active Pending
-
1997
- 1997-02-10 MX MX9707771A patent/MX9707771A/es unknown
- 1997-02-10 AU AU17682/97A patent/AU1768297A/en not_active Abandoned
- 1997-02-10 PL PL97322779A patent/PL322779A1/xx unknown
- 1997-02-10 NZ NZ328895A patent/NZ328895A/xx unknown
- 1997-02-10 EA EA199700318A patent/EA199700318A1/ru unknown
- 1997-02-10 IL IL12185397A patent/IL121853A0/xx unknown
- 1997-02-10 WO PCT/EP1997/000595 patent/WO1997030079A1/en active IP Right Grant
- 1997-02-10 BR BR9702084A patent/BR9702084A/pt unknown
- 1997-02-10 EP EP97903250A patent/EP0821696B1/en not_active Expired - Lifetime
- 1997-02-10 US US08/930,616 patent/US6245742B1/en not_active Expired - Fee Related
- 1997-02-10 CA CA002218378A patent/CA2218378A1/en not_active Abandoned
- 1997-02-10 DE DE69728938T patent/DE69728938D1/de not_active Expired - Lifetime
- 1997-02-10 HU HU9900661A patent/HUP9900661A3/hu unknown
- 1997-02-10 KR KR1019970707306A patent/KR19990007783A/ko not_active Application Discontinuation
- 1997-02-10 JP JP9528961A patent/JPH11504658A/ja not_active Withdrawn
- 1997-02-10 AT AT97903250T patent/ATE266041T1/de not_active IP Right Cessation
- 1997-02-10 CN CN97190189A patent/CN1185785A/zh active Pending
- 1997-02-12 ZA ZA9701171A patent/ZA971171B/xx unknown
- 1997-02-13 AR ARP970100572A patent/AR005808A1/es not_active Application Discontinuation
- 1997-10-14 NO NO974750A patent/NO974750L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1768297A (en) | 1997-09-02 |
| DE69728938D1 (de) | 2004-06-09 |
| NO974750L (no) | 1997-12-10 |
| KR19990007783A (ko) | 1999-01-25 |
| NZ328895A (en) | 1999-03-29 |
| EP0821696B1 (en) | 2004-05-06 |
| IL121853A0 (en) | 1998-02-22 |
| GB9603227D0 (en) | 1996-04-17 |
| JPH11504658A (ja) | 1999-04-27 |
| US6245742B1 (en) | 2001-06-12 |
| BR9702084A (pt) | 1999-07-20 |
| PL322779A1 (en) | 1998-02-16 |
| EA199700318A1 (ru) | 1998-04-30 |
| WO1997030079A1 (en) | 1997-08-21 |
| EP0821696A1 (en) | 1998-02-04 |
| HUP9900661A2 (hu) | 1999-08-30 |
| NO974750D0 (no) | 1997-10-14 |
| HUP9900661A3 (en) | 2000-03-28 |
| ATE266041T1 (de) | 2004-05-15 |
| ZA971171B (en) | 1997-09-03 |
| CN1185785A (zh) | 1998-06-24 |
| MX9707771A (es) | 1997-12-31 |
| CA2218378A1 (en) | 1997-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |