ATE266041T1 - Peptidantagonisten der zellulären mitogenese und motogenese und deren therapeutische verwendung - Google Patents

Peptidantagonisten der zellulären mitogenese und motogenese und deren therapeutische verwendung

Info

Publication number
ATE266041T1
ATE266041T1 AT97903250T AT97903250T ATE266041T1 AT E266041 T1 ATE266041 T1 AT E266041T1 AT 97903250 T AT97903250 T AT 97903250T AT 97903250 T AT97903250 T AT 97903250T AT E266041 T1 ATE266041 T1 AT E266041T1
Authority
AT
Austria
Prior art keywords
motogenesis
therapeutic use
peptide antagonists
mitogenesis
cellular
Prior art date
Application number
AT97903250T
Other languages
English (en)
Inventor
Carlo Battistini
Patrizia Giordano
Rosa Sabrina De
Fabio Corradi
Paolo Comoglio
Alberto Bardelli
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Application granted granted Critical
Publication of ATE266041T1 publication Critical patent/ATE266041T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
AT97903250T 1996-02-15 1997-02-10 Peptidantagonisten der zellulären mitogenese und motogenese und deren therapeutische verwendung ATE266041T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9603227.1A GB9603227D0 (en) 1996-02-15 1996-02-15 Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use
PCT/EP1997/000595 WO1997030079A1 (en) 1996-02-15 1997-02-10 Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use

Publications (1)

Publication Number Publication Date
ATE266041T1 true ATE266041T1 (de) 2004-05-15

Family

ID=10788833

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97903250T ATE266041T1 (de) 1996-02-15 1997-02-10 Peptidantagonisten der zellulären mitogenese und motogenese und deren therapeutische verwendung

Country Status (21)

Country Link
US (1) US6245742B1 (de)
EP (1) EP0821696B1 (de)
JP (1) JPH11504658A (de)
KR (1) KR19990007783A (de)
CN (1) CN1185785A (de)
AR (1) AR005808A1 (de)
AT (1) ATE266041T1 (de)
AU (1) AU1768297A (de)
BR (1) BR9702084A (de)
CA (1) CA2218378A1 (de)
DE (1) DE69728938D1 (de)
EA (1) EA199700318A1 (de)
GB (1) GB9603227D0 (de)
HU (1) HUP9900661A3 (de)
IL (1) IL121853A0 (de)
MX (1) MX9707771A (de)
NO (1) NO974750L (de)
NZ (1) NZ328895A (de)
PL (1) PL322779A1 (de)
WO (1) WO1997030079A1 (de)
ZA (1) ZA971171B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787793B1 (fr) * 1998-12-24 2001-03-23 Inst Nat Sante Rech Med Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant
US20020055463A1 (en) * 1998-12-24 2002-05-09 Christiane Garbay Pseudopeptide compounds having an inhibiting activity with respect to paths activated by proteins with active tyrosine kinase activity and pharmaceutical compositions containing same
FR2793796A1 (fr) * 1999-04-14 2000-11-24 Hoechst Marion Roussel Inc Nouveaux derives d'imidazoles, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2796381A1 (fr) * 1999-07-12 2001-01-19 Hoechst Marion Roussel Inc Derives bicycliques de thioazepine ou de caprolactame, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
US20040191926A1 (en) * 2001-09-26 2004-09-30 Zhong-Yin Zhang Ptp1b inhibitors and ligands
US7736911B2 (en) * 2004-04-15 2010-06-15 Albert Einstein College Of Medicine Of Yeshiva University Activity-based probes for protein tyrosine phosphatases
CA2675495A1 (en) 2007-02-26 2008-09-04 Stemcell Technologies Inc. Methods for improving culture vessel assays
US8703072B2 (en) 2008-09-12 2014-04-22 Oliver Egeler Cell culture vessels for meniscus reduction with aqueous solutions
CN103387602B (zh) * 2012-05-09 2018-07-06 中国科学院上海药物研究所 一种新型开链四肽类似物及其制备方法和用途
US10537891B2 (en) 2013-01-10 2020-01-21 Stemcell Technologies Inc. Meniscus reducing member
CN105073587B (zh) 2013-01-10 2018-01-09 干细胞技术公司 弯月面降低构件

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801149A (en) * 1991-06-19 1998-09-01 Joslin D-Abetes Center, Inc. Inhibition of signal transduction molecules
US5739278A (en) * 1993-05-10 1998-04-14 University Of Washington Compositions for protein tyrosine phosphatases
RU2146262C1 (ru) * 1993-06-30 2000-03-10 Фармация Энд Апджон С.П.А. Пептиды, способ их получения, фармацевтическая композиция и способ ее получения
WO1996023813A1 (en) * 1995-02-01 1996-08-08 Affymax Technologies N.V. Peptides and compounds that bind to sh2 domains
GB9517060D0 (en) * 1995-08-17 1995-10-25 Ciba Geigy Ag Acylated oligopeptide derivatives
GB9516842D0 (en) * 1995-08-17 1995-10-18 Ciba Geigy Ag Various acylated oligopeptides

Also Published As

Publication number Publication date
AU1768297A (en) 1997-09-02
NO974750L (no) 1997-12-10
AR005808A1 (es) 1999-07-14
US6245742B1 (en) 2001-06-12
HUP9900661A3 (en) 2000-03-28
EP0821696A1 (de) 1998-02-04
NO974750D0 (no) 1997-10-14
DE69728938D1 (de) 2004-06-09
EA199700318A1 (ru) 1998-04-30
NZ328895A (en) 1999-03-29
KR19990007783A (ko) 1999-01-25
EP0821696B1 (de) 2004-05-06
JPH11504658A (ja) 1999-04-27
HUP9900661A2 (hu) 1999-08-30
CN1185785A (zh) 1998-06-24
GB9603227D0 (en) 1996-04-17
ZA971171B (en) 1997-09-03
CA2218378A1 (en) 1997-08-21
PL322779A1 (en) 1998-02-16
WO1997030079A1 (en) 1997-08-21
BR9702084A (pt) 1999-07-20
MX9707771A (es) 1997-12-31
IL121853A0 (en) 1998-02-22

Similar Documents

Publication Publication Date Title
DE69831755D1 (de) Optoakustische kontrastmittel und anwendungsverfahren
DE69736994D1 (de) Ionische Malonsäuredinitril Derivate und deren Verwendung
ATE205185T1 (de) Benzamid-derivate und deren verwendung als vasopressin-antagonisten
DE69835020D1 (de) Plasmabrenner und verwendungsverfahren dieses plasmabrenners
DE59802439D1 (de) Spiroverbindungen und deren verwendung
DE69622148D1 (de) Chinazozin derivate und deren verwendung
DE59711847D1 (de) Substituierte aza- und diazacycloheptan- und -cyclooctanverbindungen und deren verwendung
DE69528342T2 (de) Teilchenförmige Schaumkontrollmittel und ihre Verwendung
CZ174399A3 (cs) Derivát benzamidu substituovaný heterocyklickými skupinami a jeho použití
DE69223266D1 (de) Peptidderivate und deren Verwendung
DE69716062T2 (de) Benzofuran-derivate und deren verwendung
DE59710130D1 (de) Verwendung verbindungsverfahrens und verbindungsverfahren
DE69230654D1 (de) Commiphora-Mukul-Extrakte und deren therapeutische Verwendung
ATE266041T1 (de) Peptidantagonisten der zellulären mitogenese und motogenese und deren therapeutische verwendung
DE59708905D1 (de) Injektionsformulierungen von avermectinen und milbemycinen
DE69835007D1 (de) Entkoffeinierte mate-extrakte und deren verwendung
ATE246673T1 (de) Inhibitoren der produktion von s-cd23 und der secretion von tnf
DE69715886T2 (de) Acylaminoalkenylen-amid-derivate als nk1 und nk2 antagonisten
DE1017910T1 (de) Element und system für dachverkleidungen und anwendung dieser elemente
DE69524590D1 (de) Zusammensetzung von 5htida und 5htid antagonisten
DE59809268D1 (de) Injektor und dessen Verwendung zum Besprühen von Katalysatorbetten
DE69706128T2 (de) Estermischung und ihre verwendung
DE59700145D1 (de) Trainingsstation und Verwendung der Trainingsstation
DE69822200D1 (de) Verwendung neuer liganden des hfgan72 neuropeptiderezeptors und dessen antagonisten in der therapie
DE69328467D1 (de) Polyamidzusammensetzung und Verwendung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties