AP772A - Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine. - Google Patents

Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine. Download PDF

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Publication number
AP772A
AP772A APAP/P/1998/001289A AP9801289A AP772A AP 772 A AP772 A AP 772A AP 9801289 A AP9801289 A AP 9801289A AP 772 A AP772 A AP 772A
Authority
AP
ARIPO
Prior art keywords
adenosine
acid
compounds
thienyl
ethyl
Prior art date
Application number
APAP/P/1998/001289A
Other languages
English (en)
Other versions
AP9801289A0 (en
Inventor
Larry K Truesdale
James P Sherbine
Benoit J Vanasse
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of AP9801289A0 publication Critical patent/AP9801289A0/xx
Application granted granted Critical
Publication of AP772A publication Critical patent/AP772A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
APAP/P/1998/001289A 1996-01-02 1996-12-23 Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine. AP772A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US949296P 1996-01-02 1996-01-02
PCT/US1996/020768 WO1997024327A1 (en) 1996-01-02 1996-12-23 Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine

Publications (2)

Publication Number Publication Date
AP9801289A0 AP9801289A0 (en) 1998-09-30
AP772A true AP772A (en) 1999-10-15

Family

ID=21737998

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1998/001289A AP772A (en) 1996-01-02 1996-12-23 Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine.

Country Status (22)

Country Link
US (2) US6307054B1 (sk)
EP (1) EP0909270B1 (sk)
JP (1) JP2000502709A (sk)
KR (1) KR19990076966A (sk)
AP (1) AP772A (sk)
AT (1) ATE219767T1 (sk)
AU (1) AU722894B2 (sk)
BR (1) BR9612341A (sk)
CA (1) CA2241887C (sk)
CZ (1) CZ203998A3 (sk)
DE (1) DE69622051T2 (sk)
DK (1) DK0909270T3 (sk)
EA (1) EA000884B1 (sk)
ES (1) ES2178725T3 (sk)
HK (1) HK1019590A1 (sk)
HU (1) HUP9900969A3 (sk)
IL (1) IL125164A (sk)
OA (1) OA10803A (sk)
PT (1) PT909270E (sk)
SI (1) SI9620137B (sk)
SK (1) SK283625B6 (sk)
WO (1) WO1997024327A1 (sk)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1140933T1 (en) 1998-12-31 2005-02-28 Aventis Pharmaceuticals Inc. Process for preparing n6-substituted deaza-adenosine derivatives
US7018365B2 (en) 1999-05-21 2006-03-28 Micro Therapeutics, Inc. Threaded syringe with quick stop
US6784165B1 (en) * 1999-11-23 2004-08-31 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
US7291603B2 (en) 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
MXPA05011428A (es) * 2003-04-24 2006-05-31 Aderis Pharmaceuticals Inc Metodo de tratamiento de fibrilacion atrial o trepidacion auricular.
WO2005025545A2 (en) * 2003-09-17 2005-03-24 Aderis Pharmaceuticals, Inc. Pharmaceutical formulation for controlled release of selodenoson
GT200500281A (es) * 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0500785D0 (en) * 2005-01-14 2005-02-23 Novartis Ag Organic compounds
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607950D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607948D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
ES2440317T3 (es) * 2006-04-21 2014-01-28 Novartis Ag Derivados de purina para su uso como agonistas del receptor de adenosina A2A
EP1889846A1 (en) 2006-07-13 2008-02-20 Novartis AG Purine derivatives as A2a agonists
EP1903044A1 (en) * 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
AU2007316715A1 (en) * 2006-11-10 2008-05-15 Novartis Ag Cyclopentene diol monoacetate derivatives
JP2012516843A (ja) 2009-02-02 2012-07-26 インドコ レメディーズ リミテッド ニトロピリジン誘導体の調製方法
CN114349873B (zh) * 2021-04-12 2023-03-17 杭州安誉科技有限公司 用于多孔模块辅助控制装置的高强度风扇支架

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3682929A (en) * 1968-01-08 1972-08-08 Glanzstoff Ag Aromatic bis-(2,4-dihydroxypyridine) compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547935A (en) * 1967-08-07 1970-12-15 American Cyanamid Co Certain nitro-4-pyridinols,n-oxides thereof and derivatives thereof
DE3308449A1 (de) * 1982-08-19 1984-03-15 Rütgerswerke AG, 6000 Frankfurt Verfahren zur reindarstellung von 2-chlor-6-alkoxy-3-nitropyridinen
JP3261190B2 (ja) * 1993-01-27 2002-02-25 広栄化学工業株式会社 2−ヒドロキシ−3,5−ジニトロピリジン類の製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3682929A (en) * 1968-01-08 1972-08-08 Glanzstoff Ag Aromatic bis-(2,4-dihydroxypyridine) compounds

Also Published As

Publication number Publication date
HK1019590A1 (en) 2000-02-18
CZ203998A3 (cs) 1999-11-17
ATE219767T1 (de) 2002-07-15
AU1354697A (en) 1997-07-28
IL125164A (en) 2003-03-12
US6307054B1 (en) 2001-10-23
AP9801289A0 (en) 1998-09-30
PT909270E (pt) 2002-11-29
JP2000502709A (ja) 2000-03-07
DK0909270T3 (da) 2002-10-07
WO1997024327A1 (en) 1997-07-10
SI9620137B (sl) 2006-02-28
US6392049B1 (en) 2002-05-21
DE69622051T2 (de) 2003-01-23
EA000884B1 (ru) 2000-06-26
EP0909270A4 (sk) 1999-04-21
EP0909270A1 (en) 1999-04-21
ES2178725T3 (es) 2003-01-01
KR19990076966A (ko) 1999-10-25
CA2241887A1 (en) 1997-07-10
HUP9900969A2 (hu) 1999-07-28
BR9612341A (pt) 1999-12-28
EP0909270B1 (en) 2002-06-26
SK90698A3 (en) 2000-12-11
SK283625B6 (sk) 2003-10-07
EA199800621A1 (ru) 1999-02-25
DE69622051D1 (de) 2002-08-01
OA10803A (en) 2003-01-28
CA2241887C (en) 2004-02-24
HUP9900969A3 (en) 2001-11-28
IL125164A0 (en) 1999-01-26
SI9620137A (sl) 1999-02-28
AU722894B2 (en) 2000-08-10

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AP772A (en) Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine.