AP742A - Pharmaceutical aerosol formualtions containing fluorinated surfactants. - Google Patents

Pharmaceutical aerosol formualtions containing fluorinated surfactants. Download PDF

Info

Publication number
AP742A
AP742A APAP/P/1997/000951A AP9700951A AP742A AP 742 A AP742 A AP 742A AP 9700951 A AP9700951 A AP 9700951A AP 742 A AP742 A AP 742A
Authority
AP
ARIPO
Prior art keywords
formulation according
medicament
surfactant
integer
hydrogen
Prior art date
Application number
APAP/P/1997/000951A
Other languages
English (en)
Other versions
AP9700951A0 (en
Inventor
Li Li-Bovet
Keith Arthur Johnson
Original Assignee
Glaxo Wellcome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc
Publication of AP9700951A0 publication Critical patent/AP9700951A0/xx
Application granted granted Critical
Publication of AP742A publication Critical patent/AP742A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
APAP/P/1997/000951A 1994-09-28 1995-09-27 Pharmaceutical aerosol formualtions containing fluorinated surfactants. AP742A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9419536A GB9419536D0 (en) 1994-09-28 1994-09-28 Medicaments
PCT/IB1995/000866 WO1996009816A1 (en) 1994-09-28 1995-09-27 Medicaments

Publications (2)

Publication Number Publication Date
AP9700951A0 AP9700951A0 (en) 1997-04-30
AP742A true AP742A (en) 1999-04-26

Family

ID=10762008

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/000951A AP742A (en) 1994-09-28 1995-09-27 Pharmaceutical aerosol formualtions containing fluorinated surfactants.

Country Status (32)

Country Link
US (1) US5849265A (ro)
EP (1) EP0783302B1 (ro)
JP (1) JPH10506887A (ro)
KR (1) KR100375469B1 (ro)
CN (1) CN1084614C (ro)
AP (1) AP742A (ro)
AT (1) ATE187063T1 (ro)
AU (1) AU707922B2 (ro)
BG (1) BG62839B1 (ro)
BR (1) BR9509108A (ro)
CZ (1) CZ286356B6 (ro)
DE (1) DE69513671T2 (ro)
DK (1) DK0783302T3 (ro)
EE (1) EE03380B1 (ro)
ES (1) ES2140706T3 (ro)
FI (1) FI971279A7 (ro)
GB (1) GB9419536D0 (ro)
GE (1) GEP20002140B (ro)
GR (1) GR3032245T3 (ro)
HU (1) HU221856B1 (ro)
IS (1) IS1991B (ro)
MD (1) MD1900C2 (ro)
MX (1) MX9702149A (ro)
NO (1) NO313658B1 (ro)
NZ (1) NZ292995A (ro)
OA (1) OA10603A (ro)
PL (1) PL181453B1 (ro)
RO (1) RO118564B1 (ro)
RU (1) RU2157188C2 (ro)
SK (1) SK281519B6 (ro)
UA (1) UA47412C2 (ro)
WO (1) WO1996009816A1 (ro)

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US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
US6984404B1 (en) 1998-11-18 2006-01-10 University Of Florida Research Foundation, Inc. Methods for preparing coated drug particles and pharmaceutical formulations thereof
DK1169019T3 (da) * 1999-04-14 2003-06-02 Glaxo Group Ltd Farmaceutisk aerosolformulering
US6406745B1 (en) * 1999-06-07 2002-06-18 Nanosphere, Inc. Methods for coating particles and particles produced thereby
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
US6451287B1 (en) 2000-05-26 2002-09-17 Smithkline Beecham Corporation Fluorinated copolymer surfactants and use thereof in aerosol compositions
GB0016876D0 (en) * 2000-07-11 2000-08-30 Astrazeneca Ab Novel formulation
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
SI1305329T2 (sl) * 2000-08-05 2015-07-31 Glaxo Group Limited S-fluorometil ester 6alfa,9alfa-difluoro-17alfa-(2-furanilkarboksil)oksi-11beta-hidroksi- 16alfa-metil-3-okso-androst-1,4-dien-17-karbotiojske kisline kot protivnetno sredstvo
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US7217409B2 (en) 2000-09-22 2007-05-15 Smithkline Beecham Corporation Alkanoic acid derivatives
GB0106046D0 (en) 2001-03-12 2001-05-02 Glaxo Group Ltd Canister
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
CA2445839A1 (en) * 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
JP2005500290A (ja) * 2001-06-12 2005-01-06 グラクソ　グループ　リミテッド 抗炎症性の、１７β−カルボチオアートアンドロスタン誘導体である１７α複素環エステル
GB0118364D0 (en) * 2001-07-27 2001-09-19 Glaxo Group Ltd Compounds
US7195752B2 (en) * 2001-08-03 2007-03-27 Glaxo Group Limited Surfactant compounds and uses thereof
GB0125127D0 (en) 2001-10-19 2001-12-12 Glaxo Group Ltd Compounds
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
AU2003205860A1 (en) * 2002-02-13 2003-09-04 Glaxo Group Limited Carboxylic acid compounds for use as surfactants
GB0205327D0 (en) * 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
AU2004264941B2 (en) 2003-08-11 2008-11-27 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
CN1874756B (zh) 2003-08-29 2012-02-29 葛兰素集团有限公司 药用计量剂量吸入器和其相关方法
US7030255B2 (en) * 2004-03-09 2006-04-18 Lyondell Chemical Technology, L.P. Oxidation process with in-situ H202 generation and polymer-encapsulated catalysts therefor
CA2581999C (en) * 2004-10-12 2013-04-23 Generics (Uk) Limited Preparation of suspension aerosol formulations
EP1949891A1 (en) 2004-10-12 2008-07-30 Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
ES2691033T3 (es) 2007-02-11 2018-11-23 Map Pharmaceuticals Inc. Método de administración terapéutica de DHE para activar el alivio rápido de la migraña a la vez que se reduce al mínimo el perfil de los efectos secundarios
GB0712454D0 (en) * 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344930A (en) * 1989-06-22 1994-09-06 Alliance Pharmaceutical Corp. Fluorine and phosphorous-containing amphiphilic molecules with surfactant properties

Family Cites Families (11)

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JPS5529524A (en) * 1978-08-21 1980-03-01 Toyo Aerosol Kogyo Kk Powdery aerosol composition
US4352789A (en) * 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US4965066A (en) * 1989-06-06 1990-10-23 E. I. Du Pont De Nemours And Company Intranasal administration of 3,3-disubstituted indolines
GB8921222D0 (en) * 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
IE67185B1 (en) * 1990-02-02 1996-03-06 Fisons Plc Propellant compositions
DE4003272A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
ES2071306T3 (es) * 1990-03-23 1995-06-16 Minnesota Mining & Mfg El uso de tensioactivos fluorados solubles para la preparacion de formulaciones aerosoles dosificadas.
EP0536204B1 (en) * 1990-06-27 1994-04-06 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
US5126123A (en) * 1990-06-28 1992-06-30 Glaxo, Inc. Aerosol drug formulations

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US5344930A (en) * 1989-06-22 1994-09-06 Alliance Pharmaceutical Corp. Fluorine and phosphorous-containing amphiphilic molecules with surfactant properties

Also Published As

Publication number Publication date
JPH10506887A (ja) 1998-07-07
EP0783302B1 (en) 1999-12-01
PL319342A1 (en) 1997-08-04
BG62839B1 (bg) 2000-09-29
IS1991B (is) 2005-02-15
DE69513671D1 (de) 2000-01-05
GEP20002140B (en) 2000-06-25
BR9509108A (pt) 1998-07-14
GR3032245T3 (en) 2000-04-27
EE03380B1 (et) 2001-04-16
MX9702149A (es) 1998-04-30
CZ93697A3 (en) 1997-08-13
CN1168630A (zh) 1997-12-24
AP9700951A0 (en) 1997-04-30
FI971279L (fi) 1997-03-26
OA10603A (en) 2002-08-30
MD1900C2 (ro) 2002-12-31
SK39397A3 (en) 1997-10-08
MD970134A (ro) 1999-02-28
NO971422D0 (no) 1997-03-25
IS4438A (is) 1997-03-10
HU221856B1 (hu) 2003-02-28
FI971279A0 (fi) 1997-03-26
NZ292995A (en) 1998-10-28
WO1996009816A1 (en) 1996-04-04
ES2140706T3 (es) 2000-03-01
US5849265A (en) 1998-12-15
RU2157188C2 (ru) 2000-10-10
DE69513671T2 (de) 2000-04-06
NO313658B1 (no) 2002-11-11
DK0783302T3 (da) 2000-05-29
AU707922B2 (en) 1999-07-22
BG101347A (en) 1997-12-30
ATE187063T1 (de) 1999-12-15
KR970705981A (ko) 1997-11-03
FI971279A7 (fi) 1997-03-26
KR100375469B1 (ko) 2003-10-17
AU3532195A (en) 1996-04-19
UA47412C2 (uk) 2002-07-15
RO118564B1 (ro) 2003-07-30
EE9700061A (et) 1997-08-15
PL181453B1 (pl) 2001-07-31
HUT77377A (hu) 1998-04-28
CN1084614C (zh) 2002-05-15
EP0783302A1 (en) 1997-07-16
SK281519B6 (sk) 2001-04-09
CZ286356B6 (cs) 2000-03-15
MD1900B2 (ro) 2002-04-30
GB9419536D0 (en) 1994-11-16
NO971422L (no) 1997-05-23

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