MD1900C2 - Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratorii - Google Patents
Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratoriiInfo
- Publication number
- MD1900C2 MD1900C2 MD97-0134A MD970134A MD1900C2 MD 1900 C2 MD1900 C2 MD 1900C2 MD 970134 A MD970134 A MD 970134A MD 1900 C2 MD1900 C2 MD 1900C2
- Authority
- MD
- Moldova
- Prior art keywords
- treatment
- aerosol composition
- pharmaceutical aerosol
- affections
- respiratory
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000008249 pharmaceutical aerosol Substances 0.000 title abstract 2
- 230000000241 respiratory effect Effects 0.000 title abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- KYKAJFCTULSVSH-UHFFFAOYSA-N chloro(fluoro)methane Chemical compound F[C]Cl KYKAJFCTULSVSH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Este revendicată o compoziţie farmaceutică de aerosol, ce conţine medicament pulverulent, propelent de fluorură de carbon sau clorfluorură de carbon cu conţinut de hidrogen şi substanţă tensioactivă cu formula generală (I):în care n reprezintă un număr întreg cuprins între 1 … 18;m reprezintă un număr întreg cuprins între 0 …17;R1, R2 şi R3 fiecare independent reprezintă un atom de hidrogen sau o grupă C1-4alchil.De asemenea este revendicată o metodă de tratament al afecţiunilor respiratorii cu ajutorul acestei compoziţii farmaceutice.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9419536A GB9419536D0 (en) | 1994-09-28 | 1994-09-28 | Medicaments |
PCT/IB1995/000866 WO1996009816A1 (en) | 1994-09-28 | 1995-09-27 | Medicaments |
Publications (3)
Publication Number | Publication Date |
---|---|
MD970134A MD970134A (ro) | 1999-02-28 |
MD1900B2 MD1900B2 (ro) | 2002-04-30 |
MD1900C2 true MD1900C2 (ro) | 2002-12-31 |
Family
ID=10762008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MD97-0134A MD1900C2 (ro) | 1994-09-28 | 1995-09-27 | Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratorii |
Country Status (32)
Country | Link |
---|---|
US (1) | US5849265A (ro) |
EP (1) | EP0783302B1 (ro) |
JP (1) | JPH10506887A (ro) |
KR (1) | KR100375469B1 (ro) |
CN (1) | CN1084614C (ro) |
AP (1) | AP742A (ro) |
AT (1) | ATE187063T1 (ro) |
AU (1) | AU707922B2 (ro) |
BG (1) | BG62839B1 (ro) |
BR (1) | BR9509108A (ro) |
CZ (1) | CZ286356B6 (ro) |
DE (1) | DE69513671T2 (ro) |
DK (1) | DK0783302T3 (ro) |
EE (1) | EE03380B1 (ro) |
ES (1) | ES2140706T3 (ro) |
FI (1) | FI971279A (ro) |
GB (1) | GB9419536D0 (ro) |
GE (1) | GEP20002140B (ro) |
GR (1) | GR3032245T3 (ro) |
HU (1) | HU221856B1 (ro) |
IS (1) | IS1991B (ro) |
MD (1) | MD1900C2 (ro) |
MX (1) | MX9702149A (ro) |
NO (1) | NO313658B1 (ro) |
NZ (1) | NZ292995A (ro) |
OA (1) | OA10603A (ro) |
PL (1) | PL181453B1 (ro) |
RO (1) | RO118564B1 (ro) |
RU (1) | RU2157188C2 (ro) |
SK (1) | SK281519B6 (ro) |
UA (1) | UA47412C2 (ro) |
WO (1) | WO1996009816A1 (ro) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9410222D0 (en) * | 1994-05-21 | 1994-07-06 | Glaxo Wellcome Australia Ltd | Medicaments |
US6039932A (en) * | 1996-09-27 | 2000-03-21 | 3M Innovative Properties Company | Medicinal inhalation aerosol formulations containing budesonide |
US6598603B1 (en) * | 1997-12-31 | 2003-07-29 | Astra Aktiebolag | Method for treating respiratory diseases |
US6984404B1 (en) | 1998-11-18 | 2006-01-10 | University Of Florida Research Foundation, Inc. | Methods for preparing coated drug particles and pharmaceutical formulations thereof |
WO2000061108A1 (en) * | 1999-04-14 | 2000-10-19 | Glaxo Group Limited | Pharmaceutical aerosol formulation |
US6406745B1 (en) | 1999-06-07 | 2002-06-18 | Nanosphere, Inc. | Methods for coating particles and particles produced thereby |
GB0009606D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Therapeutic combinations |
US6451287B1 (en) | 2000-05-26 | 2002-09-17 | Smithkline Beecham Corporation | Fluorinated copolymer surfactants and use thereof in aerosol compositions |
GB0016876D0 (en) * | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Novel formulation |
US6858596B2 (en) * | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
GB0019172D0 (en) * | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
US6858593B2 (en) * | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6777399B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6759398B2 (en) | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
US6750210B2 (en) * | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
US6787532B2 (en) * | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
US6777400B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
AR032471A1 (es) * | 2000-08-05 | 2003-11-12 | Glaxo Group Ltd | Derivado de androstano y solvatos del mismo, su uso para la fabricacion de medicamentos, composiciones farmaceuticas que los comprenden, procesos para preparar tales derivados, intermediarios utiles en la preparacion de tales derivados, procesos para preparar tales intermediarios, y compuestos inter |
WO2002024623A2 (en) | 2000-09-22 | 2002-03-28 | Glaxo Group Limited | Novel alkanoic acid derivatives |
GB0106046D0 (en) | 2001-03-12 | 2001-05-02 | Glaxo Group Ltd | Canister |
UA77656C2 (en) * | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
CA2445839A1 (en) * | 2001-04-30 | 2002-11-07 | Glaxo Group Limited | Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha |
US20040248867A1 (en) * | 2001-06-12 | 2004-12-09 | Keith Biggadike | Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives |
GB0118364D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxo Group Ltd | Compounds |
CA2456052A1 (en) * | 2001-08-03 | 2003-02-20 | Glaxo Group Limited | Surfactant compounds and uses thereof |
GB0125127D0 (en) | 2001-10-19 | 2001-12-12 | Glaxo Group Ltd | Compounds |
US6702997B2 (en) | 2001-10-26 | 2004-03-09 | Dey, L.P. | Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma |
JP2003221335A (ja) | 2001-10-26 | 2003-08-05 | Dey Lp | 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法 |
US20030203930A1 (en) * | 2001-10-26 | 2003-10-30 | Imtiaz Chaudry | Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
US20030191151A1 (en) * | 2001-10-26 | 2003-10-09 | Imtiaz Chaudry | Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
US20030140920A1 (en) * | 2001-10-26 | 2003-07-31 | Dey L.P. | Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma |
US20050175545A1 (en) * | 2002-02-04 | 2005-08-11 | Keith Biggadike | Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist |
GB0202635D0 (en) * | 2002-02-05 | 2002-03-20 | Glaxo Wellcome Mfg Pte Ltd | Formulation containing novel anti-inflammatory androstane derivative |
CN1633407A (zh) * | 2002-02-13 | 2005-06-29 | 葛兰素集团有限公司 | 用作表面活性剂的羧酸化合物 |
GB0205327D0 (en) * | 2002-03-06 | 2002-04-17 | Glaxo Group Ltd | compounds |
GB2389530B (en) * | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
EP2275479A1 (en) | 2003-08-11 | 2011-01-19 | Glaxo Group Limited | Pharmaceutical metered dose inhaler and methods relating thereto |
US20080190418A1 (en) | 2003-08-29 | 2008-08-14 | Glaxo Group Limited | Pharmaceutical Metered Dose Inhaler and Methods Relating Thereto |
US7030255B2 (en) * | 2004-03-09 | 2006-04-18 | Lyondell Chemical Technology, L.P. | Oxidation process with in-situ H202 generation and polymer-encapsulated catalysts therefor |
EP1949891A1 (en) | 2004-10-12 | 2008-07-30 | Generics (UK) Limited | Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister |
ATE404186T1 (de) * | 2004-10-12 | 2008-08-15 | Generics Uk Ltd | Verfahren zur herstellung von suspensionsaerosolformulierungen, worin die partikel durch präzipition in einem aerosolbehälter gebildet werden |
GB0507165D0 (en) * | 2005-04-08 | 2005-05-18 | Glaxo Group Ltd | Novel crystalline pharmaceutical product |
GB0615108D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel formulations |
PL2425820T3 (pl) | 2007-02-11 | 2015-08-31 | Map Pharmaceuticals Inc | Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych |
GB0712454D0 (en) * | 2007-06-27 | 2007-08-08 | Generics Uk Ltd | Pharmaceutical compositions |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0372777A2 (en) * | 1988-12-06 | 1990-06-13 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
WO1991004011A1 (en) * | 1989-09-20 | 1991-04-04 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
WO1991011495A1 (de) * | 1990-02-03 | 1991-08-08 | Boehringer Ingelheim Kg | Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen |
WO1991011173A1 (en) * | 1990-02-02 | 1991-08-08 | Fisons Plc | Propellant compositions |
WO1991014422A1 (en) * | 1990-03-23 | 1991-10-03 | Minnesota Mining And Manufacturing Company | The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations |
WO1992000062A1 (en) * | 1990-06-27 | 1992-01-09 | Minnesota Mining And Manufacturing Company | The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations |
EP0478686A1 (en) * | 1989-06-22 | 1992-04-08 | Atta | FLUORINE AND PHOSPHORUS AMPHIPHILIC MOLECULES WITH SURFACE-ACTIVE PROPERTIES. |
US5126123A (en) * | 1990-06-28 | 1992-06-30 | Glaxo, Inc. | Aerosol drug formulations |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4352789A (en) * | 1980-03-17 | 1982-10-05 | Minnesota Mining And Manufacturing Company | Aerosol compositions containing finely divided solid materials |
GB8501015D0 (en) * | 1985-01-16 | 1985-02-20 | Riker Laboratories Inc | Drug |
-
1994
- 1994-09-28 GB GB9419536A patent/GB9419536D0/en active Pending
-
1995
- 1995-09-27 KR KR1019970702014A patent/KR100375469B1/ko not_active IP Right Cessation
- 1995-09-27 CZ CZ1997936A patent/CZ286356B6/cs not_active IP Right Cessation
- 1995-09-27 SK SK393-97A patent/SK281519B6/sk unknown
- 1995-09-27 EE EE9700061A patent/EE03380B1/xx not_active IP Right Cessation
- 1995-09-27 RU RU97106511/14A patent/RU2157188C2/ru not_active IP Right Cessation
- 1995-09-27 PL PL95319342A patent/PL181453B1/pl not_active IP Right Cessation
- 1995-09-27 AT AT95932166T patent/ATE187063T1/de not_active IP Right Cessation
- 1995-09-27 JP JP8511571A patent/JPH10506887A/ja not_active Ceased
- 1995-09-27 DK DK95932166T patent/DK0783302T3/da active
- 1995-09-27 WO PCT/IB1995/000866 patent/WO1996009816A1/en active IP Right Grant
- 1995-09-27 EP EP95932166A patent/EP0783302B1/en not_active Expired - Lifetime
- 1995-09-27 UA UA97031255A patent/UA47412C2/uk unknown
- 1995-09-27 MD MD97-0134A patent/MD1900C2/ro not_active IP Right Cessation
- 1995-09-27 GE GEAP19953636A patent/GEP20002140B/en unknown
- 1995-09-27 AU AU35321/95A patent/AU707922B2/en not_active Ceased
- 1995-09-27 ES ES95932166T patent/ES2140706T3/es not_active Expired - Lifetime
- 1995-09-27 CN CN95196444A patent/CN1084614C/zh not_active Expired - Fee Related
- 1995-09-27 MX MX9702149A patent/MX9702149A/es not_active IP Right Cessation
- 1995-09-27 RO RO97-00561A patent/RO118564B1/ro unknown
- 1995-09-27 NZ NZ292995A patent/NZ292995A/xx unknown
- 1995-09-27 AP APAP/P/1997/000951A patent/AP742A/en active
- 1995-09-27 US US08/809,764 patent/US5849265A/en not_active Expired - Fee Related
- 1995-09-27 DE DE69513671T patent/DE69513671T2/de not_active Expired - Fee Related
- 1995-09-27 BR BR9509108A patent/BR9509108A/pt not_active IP Right Cessation
- 1995-09-27 HU HU9702260A patent/HU221856B1/hu not_active IP Right Cessation
-
1997
- 1997-03-10 IS IS4438A patent/IS1991B/is unknown
- 1997-03-21 OA OA60982A patent/OA10603A/en unknown
- 1997-03-21 BG BG101347A patent/BG62839B1/bg unknown
- 1997-03-25 NO NO19971422A patent/NO313658B1/no unknown
- 1997-03-26 FI FI971279A patent/FI971279A/fi not_active Application Discontinuation
-
1999
- 1999-12-22 GR GR990403333T patent/GR3032245T3/el unknown
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0372777A2 (en) * | 1988-12-06 | 1990-06-13 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
EP0478686A1 (en) * | 1989-06-22 | 1992-04-08 | Atta | FLUORINE AND PHOSPHORUS AMPHIPHILIC MOLECULES WITH SURFACE-ACTIVE PROPERTIES. |
WO1991004011A1 (en) * | 1989-09-20 | 1991-04-04 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
WO1991011173A1 (en) * | 1990-02-02 | 1991-08-08 | Fisons Plc | Propellant compositions |
WO1991011495A1 (de) * | 1990-02-03 | 1991-08-08 | Boehringer Ingelheim Kg | Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen |
WO1991014422A1 (en) * | 1990-03-23 | 1991-10-03 | Minnesota Mining And Manufacturing Company | The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations |
WO1992000062A1 (en) * | 1990-06-27 | 1992-01-09 | Minnesota Mining And Manufacturing Company | The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations |
US5126123A (en) * | 1990-06-28 | 1992-06-30 | Glaxo, Inc. | Aerosol drug formulations |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PD99 | Pending application | ||
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |