MD1900C2 - Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratorii - Google Patents

Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratorii Download PDF

Info

Publication number
MD1900C2
MD1900C2 MD97-0134A MD970134A MD1900C2 MD 1900 C2 MD1900 C2 MD 1900C2 MD 970134 A MD970134 A MD 970134A MD 1900 C2 MD1900 C2 MD 1900C2
Authority
MD
Moldova
Prior art keywords
treatment
aerosol composition
pharmaceutical aerosol
affections
respiratory
Prior art date
Application number
MD97-0134A
Other languages
English (en)
Russian (ru)
Other versions
MD1900B2 (ro
MD970134A (ro
Inventor
Ли ЛИ-БОВЕТ
Кейт Артур Джонсон
Original Assignee
Глаксо Уелкэм Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксо Уелкэм Инк. filed Critical Глаксо Уелкэм Инк.
Publication of MD970134A publication Critical patent/MD970134A/ro
Publication of MD1900B2 publication Critical patent/MD1900B2/ro
Publication of MD1900C2 publication Critical patent/MD1900C2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

Este revendicată o compoziţie farmaceutică de aerosol, ce conţine medicament pulverulent, propelent de fluorură de carbon sau clorfluorură de carbon cu conţinut de hidrogen şi substanţă tensioactivă cu formula generală (I):în care n reprezintă un număr întreg cuprins între 1 … 18;m reprezintă un număr întreg cuprins între 0 …17;R1, R2 şi R3 fiecare independent reprezintă un atom de hidrogen sau o grupă C1-4alchil.De asemenea este revendicată o metodă de tratament al afecţiunilor respiratorii cu ajutorul acestei compoziţii farmaceutice.
MD97-0134A 1994-09-28 1995-09-27 Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratorii MD1900C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9419536A GB9419536D0 (en) 1994-09-28 1994-09-28 Medicaments
PCT/IB1995/000866 WO1996009816A1 (en) 1994-09-28 1995-09-27 Medicaments

Publications (3)

Publication Number Publication Date
MD970134A MD970134A (ro) 1999-02-28
MD1900B2 MD1900B2 (ro) 2002-04-30
MD1900C2 true MD1900C2 (ro) 2002-12-31

Family

ID=10762008

Family Applications (1)

Application Number Title Priority Date Filing Date
MD97-0134A MD1900C2 (ro) 1994-09-28 1995-09-27 Compoziţie farmaceutică de aerosol şi metodă de tratament al afecţiunilor respiratorii

Country Status (32)

Country Link
US (1) US5849265A (ro)
EP (1) EP0783302B1 (ro)
JP (1) JPH10506887A (ro)
KR (1) KR100375469B1 (ro)
CN (1) CN1084614C (ro)
AP (1) AP742A (ro)
AT (1) ATE187063T1 (ro)
AU (1) AU707922B2 (ro)
BG (1) BG62839B1 (ro)
BR (1) BR9509108A (ro)
CZ (1) CZ286356B6 (ro)
DE (1) DE69513671T2 (ro)
DK (1) DK0783302T3 (ro)
EE (1) EE03380B1 (ro)
ES (1) ES2140706T3 (ro)
FI (1) FI971279A0 (ro)
GB (1) GB9419536D0 (ro)
GE (1) GEP20002140B (ro)
GR (1) GR3032245T3 (ro)
HU (1) HU221856B1 (ro)
IS (1) IS1991B (ro)
MD (1) MD1900C2 (ro)
MX (1) MX9702149A (ro)
NO (1) NO313658B1 (ro)
NZ (1) NZ292995A (ro)
OA (1) OA10603A (ro)
PL (1) PL181453B1 (ro)
RO (1) RO118564B1 (ro)
RU (1) RU2157188C2 (ro)
SK (1) SK281519B6 (ro)
UA (1) UA47412C2 (ro)
WO (1) WO1996009816A1 (ro)

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US6406745B1 (en) 1999-06-07 2002-06-18 Nanosphere, Inc. Methods for coating particles and particles produced thereby
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US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
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US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US7217409B2 (en) 2000-09-22 2007-05-15 Smithkline Beecham Corporation Alkanoic acid derivatives
GB0106046D0 (en) 2001-03-12 2001-05-02 Glaxo Group Ltd Canister
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US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
WO2002088167A1 (en) * 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
ES2307751T3 (es) * 2001-06-12 2008-12-01 Glaxo Group Limited Nuevos esteres heterociclicos centi-inflamatorios 17 alfa de derivados 17 beta de carbotioato de androstano.
GB0118364D0 (en) * 2001-07-27 2001-09-19 Glaxo Group Ltd Compounds
JP2005501082A (ja) * 2001-08-03 2005-01-13 グラクソ　グループ　リミテッド 界面活性剤化合物およびその使用
GB0125127D0 (en) 2001-10-19 2001-12-12 Glaxo Group Ltd Compounds
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
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EP1654312B1 (en) 2003-08-11 2014-01-15 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
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EP1949891A1 (en) 2004-10-12 2008-07-30 Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
DE602005009012D1 (de) * 2004-10-12 2008-09-25 Generics Uk Ltd Rmulierungen, worin die partikel durch präzipition in einem aerosolbehälter gebildet werden
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
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Citations (8)

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EP0372777A2 (en) * 1988-12-06 1990-06-13 Riker Laboratories, Inc. Medicinal aerosol formulations
WO1991004011A1 (en) * 1989-09-20 1991-04-04 Riker Laboratories, Inc. Medicinal aerosol formulations
WO1991011495A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
WO1991011173A1 (en) * 1990-02-02 1991-08-08 Fisons Plc Propellant compositions
WO1991014422A1 (en) * 1990-03-23 1991-10-03 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
WO1992000062A1 (en) * 1990-06-27 1992-01-09 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
EP0478686A1 (en) * 1989-06-22 1992-04-08 Atta FLUORINE AND PHOSPHORUS AMPHIPHILIC MOLECULES WITH SURFACE-ACTIVE PROPERTIES.
US5126123A (en) * 1990-06-28 1992-06-30 Glaxo, Inc. Aerosol drug formulations

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EP0372777A2 (en) * 1988-12-06 1990-06-13 Riker Laboratories, Inc. Medicinal aerosol formulations
EP0478686A1 (en) * 1989-06-22 1992-04-08 Atta FLUORINE AND PHOSPHORUS AMPHIPHILIC MOLECULES WITH SURFACE-ACTIVE PROPERTIES.
WO1991004011A1 (en) * 1989-09-20 1991-04-04 Riker Laboratories, Inc. Medicinal aerosol formulations
WO1991011173A1 (en) * 1990-02-02 1991-08-08 Fisons Plc Propellant compositions
WO1991011495A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
WO1991014422A1 (en) * 1990-03-23 1991-10-03 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
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Also Published As

Publication number Publication date
AP9700951A0 (en) 1997-04-30
BR9509108A (pt) 1998-07-14
AP742A (en) 1999-04-26
AU3532195A (en) 1996-04-19
CZ286356B6 (cs) 2000-03-15
EP0783302B1 (en) 1999-12-01
JPH10506887A (ja) 1998-07-07
OA10603A (en) 2002-08-30
CN1168630A (zh) 1997-12-24
NO313658B1 (no) 2002-11-11
KR100375469B1 (ko) 2003-10-17
FI971279L (fi) 1997-03-26
HUT77377A (hu) 1998-04-28
FI971279A7 (fi) 1997-03-26
RU2157188C2 (ru) 2000-10-10
GB9419536D0 (en) 1994-11-16
MX9702149A (es) 1998-04-30
MD1900B2 (ro) 2002-04-30
DK0783302T3 (da) 2000-05-29
NZ292995A (en) 1998-10-28
BG101347A (en) 1997-12-30
EE03380B1 (et) 2001-04-16
HU221856B1 (hu) 2003-02-28
IS1991B (is) 2005-02-15
CN1084614C (zh) 2002-05-15
CZ93697A3 (en) 1997-08-13
PL319342A1 (en) 1997-08-04
RO118564B1 (ro) 2003-07-30
US5849265A (en) 1998-12-15
MD970134A (ro) 1999-02-28
NO971422D0 (no) 1997-03-25
BG62839B1 (bg) 2000-09-29
FI971279A0 (fi) 1997-03-26
WO1996009816A1 (en) 1996-04-04
ATE187063T1 (de) 1999-12-15
ES2140706T3 (es) 2000-03-01
EP0783302A1 (en) 1997-07-16
SK39397A3 (en) 1997-10-08
GEP20002140B (en) 2000-06-25
IS4438A (is) 1997-03-10
EE9700061A (et) 1997-08-15
DE69513671D1 (de) 2000-01-05
UA47412C2 (uk) 2002-07-15
NO971422L (no) 1997-05-23
SK281519B6 (sk) 2001-04-09
KR970705981A (ko) 1997-11-03
AU707922B2 (en) 1999-07-22
GR3032245T3 (en) 2000-04-27
PL181453B1 (pl) 2001-07-31
DE69513671T2 (de) 2000-04-06

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Legal Events

Date Code Title Description
PD99 Pending application
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees