AP734A - Method of treating a human with nervous insult with cyclosporin. - Google Patents
Method of treating a human with nervous insult with cyclosporin. Download PDFInfo
- Publication number
- AP734A AP734A APAP/P/1997/001049A AP9701049A AP734A AP 734 A AP734 A AP 734A AP 9701049 A AP9701049 A AP 9701049A AP 734 A AP734 A AP 734A
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- AP
- ARIPO
- Prior art keywords
- cyclosporins
- blood
- nervous
- cyclosporin
- insult
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9500209A SE520730C2 (sv) | 1995-01-20 | 1995-01-20 | Behandling av hjärnischemi och hjärnskador med ett neuroprotektivt läkemedel |
| PCT/SE1996/000036 WO1996022104A1 (en) | 1995-01-20 | 1996-01-18 | Treatment of cerebral ischemia and cerebral damage with neuroprotective agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9701049A0 AP9701049A0 (en) | 1997-10-31 |
| AP734A true AP734A (en) | 1999-02-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1997/001049A AP734A (en) | 1995-01-20 | 1996-01-18 | Method of treating a human with nervous insult with cyclosporin. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5972924A (de) |
| EP (1) | EP0813420B1 (de) |
| JP (1) | JP3643380B2 (de) |
| CN (1) | CN1123359C (de) |
| AP (1) | AP734A (de) |
| AT (1) | ATE218360T1 (de) |
| AU (1) | AU712974B2 (de) |
| CA (1) | CA2210241C (de) |
| CZ (1) | CZ291233B6 (de) |
| DE (1) | DE69621603T2 (de) |
| DK (1) | DK0813420T3 (de) |
| ES (1) | ES2176432T3 (de) |
| MX (1) | MX9706362A (de) |
| NZ (1) | NZ300699A (de) |
| PT (1) | PT813420E (de) |
| RU (1) | RU2194527C2 (de) |
| SE (1) | SE520730C2 (de) |
| WO (1) | WO1996022104A1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19711795C2 (de) * | 1997-03-21 | 2001-03-08 | Apogepha Arzneimittel Gmbh | Verwendung von Cyclosporin für die Behandlung von Myokardinfarkten und deren Folgen |
| US20030220234A1 (en) | 1998-11-02 | 2003-11-27 | Selvaraj Naicker | Deuterated cyclosporine analogs and their use as immunodulating agents |
| US20040202645A1 (en) * | 2003-04-08 | 2004-10-14 | Khan Nisar Ahmed | Administration of gene-regulatory peptides |
| EP1138692A1 (de) | 2000-03-29 | 2001-10-04 | Erasmus Universiteit Rotterdam | Fragmente des menschlichen Choriongonadotropins als Immunoregulatoren |
| US20050227925A1 (en) * | 2004-04-08 | 2005-10-13 | Robbert Benner | Compositions capable of reducing elevated blood urea concentration |
| US6844315B2 (en) | 1998-05-20 | 2005-01-18 | Erasmus Universiteit Rotterdam | Immunoregulator |
| US8680059B2 (en) * | 1998-05-20 | 2014-03-25 | Biotempt B.V. | Oligopeptide acetate and formulations thereof |
| US20030220258A1 (en) | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of ischemic events |
| US6921751B1 (en) * | 1998-05-20 | 2005-07-26 | Erasmus Universiteit Rotterdam | Immunoregulator |
| AP1040A (en) * | 1998-09-17 | 2002-01-30 | Panacea Biotec Ltd | A novel composition containing cyclosporin. |
| WO2000016794A1 (en) * | 1998-09-23 | 2000-03-30 | Marcus Keep | Neuroimmunophilins for selective neuronal radioprotection |
| DE19857609A1 (de) | 1998-12-14 | 2000-06-15 | Hannelore Ehrenreich | Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen |
| EP1191845A4 (de) * | 1999-04-13 | 2002-07-17 | Long Island Jewish Res Inst | Prävention von durch ischämie ausgelösten hirnschädigungen |
| WO2001017953A1 (en) | 1999-09-08 | 2001-03-15 | Guilford Pharmaceuticals Inc. | Non-peptidic cyclophilin binding compounds and their use |
| DE19961733A1 (de) * | 1999-12-21 | 2001-06-28 | Ciclomulsion Ag | Cyclosporin(e) enthaltende hypertone pharmazeutische Zubereitung zur Anwendung bei neurologischen Erkrankungen und als Neuroprotektivum sowie Verfahren zu ihrer Herstellung |
| KR20010069066A (ko) * | 2000-01-12 | 2001-07-23 | 이종원 | 저산소 농도하에서 생존이 가능하도록 하는 동물세포의배양방법 |
| US7358330B2 (en) * | 2001-03-29 | 2008-04-15 | Biotempt B.V. | Immunoregulatory compositions |
| EP1274377A2 (de) * | 2000-04-07 | 2003-01-15 | The General Hospital Corporation doing business as Massachusetts General Hospital | Methoden und gerät zum thermischen beeinflussen von gewebe |
| US6899726B2 (en) | 2000-10-05 | 2005-05-31 | Seacoast Technologies, Inc. | Expandable device for thermal therapy including spiral element |
| MXPA03006666A (es) | 2001-01-25 | 2004-05-31 | Guilford Pharm Inc | Compuestos de union de ciclofilina carbociclicos trisubstituidos y su uso. |
| US6936589B2 (en) * | 2001-09-28 | 2005-08-30 | Albert T. Naito | Parenteral delivery systems |
| HRP20070058B1 (hr) | 2001-10-19 | 2014-05-23 | Isotechnika Inc. | Sinteza ciklosporinskih analoga |
| US20080318871A1 (en) * | 2001-12-21 | 2008-12-25 | Khan Nisar A | Treatment of neurological disorders |
| US20030220260A1 (en) * | 2001-12-21 | 2003-11-27 | Khan Nisar Ahmed | Peptide compositions |
| US20030220257A1 (en) * | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of trauma |
| US7786084B2 (en) * | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
| US20030220261A1 (en) * | 2001-12-21 | 2003-11-27 | Khan Nisar Ahmed | Treatment of iatrogenic disease |
| US20040013661A1 (en) * | 2001-12-21 | 2004-01-22 | Gert Wensvoort | Stratification |
| US20030224995A1 (en) * | 2001-12-21 | 2003-12-04 | Khan Nisar Ahmed | Treatment of burns |
| US7501391B2 (en) * | 2001-12-21 | 2009-03-10 | Biotempt B.V. | Treatment of transplant survival |
| US20080242837A1 (en) * | 2001-12-21 | 2008-10-02 | Khan Nisar A | Peptide compositions |
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| JP2006521405A (ja) * | 2003-03-27 | 2006-09-21 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 発作回復におけるエリトロポイエチンの使用 |
| RU2265415C2 (ru) * | 2003-05-19 | 2005-12-10 | Челябинский государственный институт лазерной хирургии | Способ реваскуляризации инфарктных очагов головного мозга |
| RU2275195C2 (ru) * | 2003-06-19 | 2006-04-27 | Наталья Борисовна Кармен | Средство для защиты головного мозга от гипоксически-ишемического повреждения |
| RU2255739C2 (ru) * | 2003-07-14 | 2005-07-10 | Оренбургская государственная медицинская академия | Способ лечения ишемического инсульта в острейший период |
| US20090227505A1 (en) * | 2004-01-07 | 2009-09-10 | Biotempt B.V. | Methods and uses for protein breakdown products |
| ES2339790T3 (es) * | 2004-08-30 | 2010-05-25 | Seo Hong Yoo | Efecto neuroprotector de udca solubilizado en modelo isquemico focal. |
| US7074775B2 (en) * | 2004-09-14 | 2006-07-11 | Miller Landon C G | Aminobutyramide conjugate and a pharmaceutical composition for treatment of neuronal disorders |
| US8420602B2 (en) * | 2004-09-14 | 2013-04-16 | Landon C. G. Miller | Endocannabinoid conjugate and a pharmaceutical composition for treatment of neuronal disorders |
| WO2007004869A2 (en) * | 2005-07-05 | 2007-01-11 | Biotempt B.V. | Treatment of tumors |
| EP1864692A1 (de) | 2006-06-07 | 2007-12-12 | Biotempt B.V. | Verwendung von peptiden zum Schutz von Strahlenschäden |
| JP5243428B2 (ja) * | 2006-08-23 | 2013-07-24 | ザ ユニヴァーシティ オブ モンタナ | 神経細胞の損傷を減少させるための薬学的組成物 |
| DK2120991T3 (da) * | 2007-02-12 | 2014-04-28 | Biotempt Bv | Behandling af traumatisk blødning med korte oligopeptider |
| EP2808029A3 (de) * | 2010-03-15 | 2015-04-01 | Stealth Peptides International, Inc. | Kombinationstherapien mit Cyclosporin und aromatischen kationischen Peptiden |
| RU2475233C2 (ru) * | 2010-12-01 | 2013-02-20 | Учреждение Российской академии наук Институт кристаллографии им. А.В. Шубникова РАН | Фармакологическая композиция, предназначенная для интраназального введения с целью доставки в мозг фармакологически активного компонента, и способ ее получения |
| AU2011342284C1 (en) | 2010-12-15 | 2017-07-13 | Contravir Pharmaceuticals, Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
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| US10123969B2 (en) | 2015-10-15 | 2018-11-13 | Wisconsin Alumni Research Foundation | Osmotic enhancement of drug/therapeutic delivery to the brain following infusion or injection into the cerebrospinal fluid |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| SU1138164A1 (ru) * | 1963-04-25 | 1985-02-07 | Shadurskij Konstantin S | Антигистаминное средство "димебон |
| US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
| US5273754A (en) * | 1992-03-27 | 1993-12-28 | Mann Morris A | Appetite suppressant composition and method relating thereto |
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1995
- 1995-01-20 SE SE9500209A patent/SE520730C2/sv not_active IP Right Cessation
-
1996
- 1996-01-18 RU RU97114608/14A patent/RU2194527C2/ru active
- 1996-01-18 JP JP52220296A patent/JP3643380B2/ja not_active Expired - Lifetime
- 1996-01-18 US US08/860,898 patent/US5972924A/en not_active Expired - Lifetime
- 1996-01-18 AT AT96901587T patent/ATE218360T1/de active
- 1996-01-18 DE DE69621603T patent/DE69621603T2/de not_active Expired - Lifetime
- 1996-01-18 EP EP96901587A patent/EP0813420B1/de not_active Expired - Lifetime
- 1996-01-18 CA CA002210241A patent/CA2210241C/en not_active Expired - Lifetime
- 1996-01-18 CZ CZ19972336A patent/CZ291233B6/cs not_active IP Right Cessation
- 1996-01-18 ES ES96901587T patent/ES2176432T3/es not_active Expired - Lifetime
- 1996-01-18 AU AU45924/96A patent/AU712974B2/en not_active Expired
- 1996-01-18 NZ NZ300699A patent/NZ300699A/en not_active IP Right Cessation
- 1996-01-18 WO PCT/SE1996/000036 patent/WO1996022104A1/en not_active Ceased
- 1996-01-18 CN CN96192572A patent/CN1123359C/zh not_active Expired - Lifetime
- 1996-01-18 DK DK96901587T patent/DK0813420T3/da active
- 1996-01-18 AP APAP/P/1997/001049A patent/AP734A/en active
- 1996-01-18 PT PT96901587T patent/PT813420E/pt unknown
-
1997
- 1997-08-20 MX MX9706362A patent/MX9706362A/es unknown
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| Title |
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| ACTA NEUROCHIRURGICA, Vol. 112, 1991, M. RYBA et al., "Cyclosporine A Prevents Neurological Deterioration of Patients with SAH - A Preliminary Report", 25-27. * |
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Also Published As
| Publication number | Publication date |
|---|---|
| CZ233697A3 (cs) | 1998-07-15 |
| CA2210241C (en) | 2000-06-20 |
| SE520730C2 (sv) | 2003-08-19 |
| DE69621603T2 (de) | 2002-09-19 |
| CA2210241A1 (en) | 1996-07-25 |
| ES2176432T3 (es) | 2002-12-01 |
| JP3643380B2 (ja) | 2005-04-27 |
| SE9500209L (sv) | 1996-07-21 |
| DE69621603D1 (de) | 2002-07-11 |
| ATE218360T1 (de) | 2002-06-15 |
| EP0813420B1 (de) | 2002-06-05 |
| NZ300699A (en) | 1998-05-27 |
| CN1178469A (zh) | 1998-04-08 |
| EP0813420A1 (de) | 1997-12-29 |
| CN1123359C (zh) | 2003-10-08 |
| PT813420E (pt) | 2002-10-31 |
| DK0813420T3 (da) | 2002-09-30 |
| US5972924A (en) | 1999-10-26 |
| CZ291233B6 (cs) | 2003-01-15 |
| MX9706362A (es) | 1998-07-31 |
| JPH11504617A (ja) | 1999-04-27 |
| AU4592496A (en) | 1996-08-07 |
| AP9701049A0 (en) | 1997-10-31 |
| AU712974B2 (en) | 1999-11-18 |
| RU2194527C2 (ru) | 2002-12-20 |
| SE9500209D0 (sv) | 1995-01-20 |
| WO1996022104A1 (en) | 1996-07-25 |
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