AP338A - A carbamoylchroman compound as selective 5-hydroxytryptamine. - Google Patents
A carbamoylchroman compound as selective 5-hydroxytryptamine. Download PDFInfo
- Publication number
- AP338A AP338A APAP/P/1992/000434A AP9200434A AP338A AP 338 A AP338 A AP 338A AP 9200434 A AP9200434 A AP 9200434A AP 338 A AP338 A AP 338A
- Authority
- AP
- ARIPO
- Prior art keywords
- compound
- isopropyl
- propylamino
- carbamoylchroman
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9102905A SE9102905D0 (sv) | 1991-10-08 | 1991-10-08 | A new therapeutically active compound and a process for its preparation |
| SE9202000A SE9202000D0 (sv) | 1992-06-29 | 1992-06-29 | A new therapeutically active compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9200434A0 AP9200434A0 (en) | 1992-10-31 |
| AP338A true AP338A (en) | 1994-04-26 |
Family
ID=26661197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1992/000434A AP338A (en) | 1991-10-08 | 1992-10-08 | A carbamoylchroman compound as selective 5-hydroxytryptamine. |
Country Status (32)
| Country | Link |
|---|---|
| EP (3) | EP0703229A3 (zh) |
| JP (1) | JPH07500320A (zh) |
| CN (2) | CN1072411A (zh) |
| AP (1) | AP338A (zh) |
| AT (1) | ATE139774T1 (zh) |
| AU (1) | AU667687B2 (zh) |
| BG (1) | BG98684A (zh) |
| CA (1) | CA2118708A1 (zh) |
| CY (1) | CY1992A (zh) |
| CZ (1) | CZ51094A3 (zh) |
| DE (1) | DE69211857T2 (zh) |
| DK (1) | DK0607274T3 (zh) |
| EE (1) | EE02981B1 (zh) |
| ES (1) | ES2089571T3 (zh) |
| FI (1) | FI941616A (zh) |
| GR (1) | GR3020608T3 (zh) |
| HK (1) | HK55997A (zh) |
| HR (1) | HRP920935A2 (zh) |
| HU (1) | HUT68834A (zh) |
| IL (1) | IL103373A0 (zh) |
| IS (2) | IS1644B (zh) |
| MA (1) | MA22674A1 (zh) |
| MX (1) | MX9205744A (zh) |
| MY (1) | MY131174A (zh) |
| NO (1) | NO941256L (zh) |
| NZ (2) | NZ244618A (zh) |
| PL (1) | PL171013B1 (zh) |
| SI (1) | SI9200249A (zh) |
| SK (1) | SK36194A3 (zh) |
| TN (1) | TNSN92088A1 (zh) |
| WO (1) | WO1993007135A1 (zh) |
| YU (1) | YU90492A (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
| US5990114A (en) * | 1996-02-28 | 1999-11-23 | Recordati, S.A., Chemical And Pharmaceutical Company | Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| CA2345079C (en) * | 1998-09-23 | 2011-06-21 | Research Development Foundation | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof |
| US6235938B1 (en) * | 1999-06-10 | 2001-05-22 | Yale University | Transition metal-catalyzed process for preparing N-aryl amine compounds |
| MA45795A (fr) * | 2016-07-29 | 2019-06-05 | Sunovion Pharmaceuticals Inc | Composés et compositions, et utilisations associées |
| EP3661929B1 (en) | 2017-08-02 | 2021-07-14 | Sunovion Pharmaceuticals Inc. | Isochroman compounds and uses thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991009853A1 (en) * | 1989-12-22 | 1991-07-11 | Aktiebolaget Astra | New chroman and thiochroman derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH22522A (en) * | 1985-09-03 | 1988-10-17 | Ciba Geigy Ag | 3-amino-dihydro-1-benzopyrans and benzothiopyrans, their pharmaceutical compositions and method of using said compounds |
| US4801605A (en) * | 1986-08-29 | 1989-01-31 | Ciba-Geigy Corporation | 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans |
| SE8605504D0 (sv) * | 1986-12-19 | 1986-12-19 | Astra Laekemedel Ab | Novel chroman derivatives |
| JPH021429A (ja) * | 1988-06-09 | 1990-01-05 | Toray Ind Inc | 光学活性１−メチル−３−フェニルプロピルアミンの製造方法 |
-
1992
- 1992-10-02 HR HR920935A patent/HRP920935A2/hr not_active Application Discontinuation
- 1992-10-05 NZ NZ244618A patent/NZ244618A/en unknown
- 1992-10-05 MY MYPI92001795A patent/MY131174A/en unknown
- 1992-10-05 NZ NZ270595A patent/NZ270595A/en unknown
- 1992-10-07 MA MA22959A patent/MA22674A1/fr unknown
- 1992-10-07 IS IS3929A patent/IS1644B/is unknown
- 1992-10-07 MX MX9205744A patent/MX9205744A/es unknown
- 1992-10-08 WO PCT/SE1992/000708 patent/WO1993007135A1/en not_active Application Discontinuation
- 1992-10-08 EP EP95118114A patent/EP0703229A3/en not_active Withdrawn
- 1992-10-08 ES ES92921525T patent/ES2089571T3/es not_active Expired - Lifetime
- 1992-10-08 AT AT92921525T patent/ATE139774T1/de not_active IP Right Cessation
- 1992-10-08 DK DK92921525.9T patent/DK0607274T3/da active
- 1992-10-08 YU YU90492A patent/YU90492A/sh unknown
- 1992-10-08 CZ CZ94510A patent/CZ51094A3/cs unknown
- 1992-10-08 EP EP92921525A patent/EP0607274B1/en not_active Expired - Lifetime
- 1992-10-08 CN CN92112826A patent/CN1072411A/zh active Pending
- 1992-10-08 DE DE69211857T patent/DE69211857T2/de not_active Expired - Fee Related
- 1992-10-08 IL IL103373A patent/IL103373A0/xx unknown
- 1992-10-08 SK SK361-94A patent/SK36194A3/sk unknown
- 1992-10-08 HU HU9400993A patent/HUT68834A/hu unknown
- 1992-10-08 AP APAP/P/1992/000434A patent/AP338A/en active
- 1992-10-08 TN TNTNSN92088A patent/TNSN92088A1/fr unknown
- 1992-10-08 JP JP5506849A patent/JPH07500320A/ja active Pending
- 1992-10-08 AU AU27684/92A patent/AU667687B2/en not_active Ceased
- 1992-10-08 CA CA002118708A patent/CA2118708A1/en not_active Abandoned
- 1992-10-08 EP EP92850237A patent/EP0538222A1/en active Pending
- 1992-10-08 PL PL92303101A patent/PL171013B1/pl unknown
- 1992-10-08 SI SI19929200249A patent/SI9200249A/sl unknown
- 1992-12-08 IS IS4310A patent/IS4310A/is unknown
-
1994
- 1994-03-29 BG BG98684A patent/BG98684A/xx unknown
- 1994-04-07 NO NO941256A patent/NO941256L/no unknown
- 1994-04-08 FI FI941616A patent/FI941616A/fi not_active Application Discontinuation
- 1994-11-23 EE EE9400368A patent/EE02981B1/xx unknown
-
1996
- 1996-02-28 CN CN96103466A patent/CN1146992A/zh active Pending
- 1996-07-23 GR GR960401967T patent/GR3020608T3/el unknown
-
1997
- 1997-05-01 HK HK55997A patent/HK55997A/xx not_active IP Right Cessation
- 1997-09-05 CY CY199297A patent/CY1992A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991009853A1 (en) * | 1989-12-22 | 1991-07-11 | Aktiebolaget Astra | New chroman and thiochroman derivatives |
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