AP3340A - Novel compounds as histamine H3 receptor ligands - Google Patents
Novel compounds as histamine H3 receptor ligandsInfo
- Publication number
- AP3340A AP3340A AP2013007088A AP2013007088A AP3340A AP 3340 A AP3340 A AP 3340A AP 2013007088 A AP2013007088 A AP 2013007088A AP 2013007088 A AP2013007088 A AP 2013007088A AP 3340 A AP3340 A AP 3340A
- Authority
- AP
- ARIPO
- Prior art keywords
- histamine
- novel compounds
- receptor ligands
- ligands
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN520CH2011 | 2011-02-23 | ||
PCT/IN2011/000380 WO2012114348A1 (en) | 2011-02-23 | 2011-06-07 | Novel compounds as histamine h3 receptor ligands |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2013007088A0 AP2013007088A0 (en) | 2013-08-31 |
AP3340A true AP3340A (en) | 2015-07-31 |
Family
ID=54290090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2013007088A AP3340A (en) | 2011-02-23 | 2011-06-07 | Novel compounds as histamine H3 receptor ligands |
Country Status (28)
Country | Link |
---|---|
US (1) | US9079888B2 (es) |
EP (1) | EP2694492B1 (es) |
JP (1) | JP5805792B2 (es) |
KR (1) | KR101554407B1 (es) |
CN (1) | CN103443093B (es) |
AP (1) | AP3340A (es) |
AU (1) | AU2011360550B2 (es) |
BR (1) | BR112013021496B1 (es) |
CA (1) | CA2827567C (es) |
CY (1) | CY1116721T1 (es) |
DK (1) | DK2694492T3 (es) |
EA (1) | EA023260B1 (es) |
ES (1) | ES2548284T3 (es) |
HK (1) | HK1187613A1 (es) |
HR (1) | HRP20151003T1 (es) |
HU (1) | HUE025163T2 (es) |
IL (1) | IL228019A (es) |
ME (1) | ME02212B (es) |
MX (1) | MX339858B (es) |
NZ (1) | NZ614567A (es) |
PL (1) | PL2694492T3 (es) |
PT (1) | PT2694492E (es) |
RS (1) | RS54248B1 (es) |
SG (1) | SG192858A1 (es) |
SI (1) | SI2694492T1 (es) |
SM (1) | SMT201500238B (es) |
WO (1) | WO2012114348A1 (es) |
ZA (1) | ZA201306328B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP1300139A2 (en) * | 2013-03-06 | 2014-09-29 | Richter Gedeon Nyrt | Phenoxypiperidine h3 antagonists |
CA2957494C (en) * | 2014-08-16 | 2018-08-28 | Suven Life Sciences Limited | Process for large scale production of n-[4-(1- cyclobutyl piperidin-4-yloxy) phenyl]-2-(morpholin-4-yl) acetamide dihydrochloride |
ME03812B (me) * | 2016-08-18 | 2021-04-20 | Suven Life Sciences Ltd | Kombinacija inverznih agonista histamin-3 receptora sa inhibitorima acetilholinesteraze |
JP6734469B2 (ja) * | 2016-08-18 | 2020-08-05 | スヴェン・ライフ・サイエンシーズ・リミテッドSuven Life Sciences Limited | ヒスタミン−3受容体インバースアゴニスト、アセチルコリンエステラーゼ阻害剤及びnmda受容体アンタゴニストの3種組合せ |
WO2019229509A1 (en) | 2018-05-31 | 2019-12-05 | Suven Life Sciences Limited | Method of treatment with histamine-3 receptor inverse agonist |
WO2022113008A1 (en) | 2020-11-27 | 2022-06-02 | Richter Gedeon Nyrt. | Histamine h3 receptor antagonists/inverse agonists for the treatment of autism spectrum disorder |
CN116693446A (zh) * | 2022-03-02 | 2023-09-05 | 杭州百诚医药科技股份有限公司 | 苯基脲类衍生物及其医药用途 |
WO2023166351A1 (zh) * | 2022-03-02 | 2023-09-07 | 杭州百诚医药科技股份有限公司 | 组胺h3受体抑制剂及其医药用途 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100048580A1 (en) * | 2004-04-01 | 2010-02-25 | Lisa Selsam Beavers | Histamine h3 receptor agents, preparation and therapeutic uses |
WO2010045306A2 (en) * | 2008-10-16 | 2010-04-22 | Schering Corporation | Azine derivatives and methods of use thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9725541D0 (en) * | 1997-12-02 | 1998-02-04 | Pharmacia & Upjohn Spa | Amino-benzothiazole derivatives |
WO2002012190A2 (en) * | 2000-08-08 | 2002-02-14 | Ortho Mcneil Pharmaceutical, Inc. | Non-imidazole aryloxypiperidines as h3 receptor ligands |
EP1379493A2 (en) * | 2001-03-23 | 2004-01-14 | Eli Lilly and Company | Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses |
RU2423353C1 (ru) * | 2002-12-20 | 2011-07-10 | Глэксо Груп Лимитед | Новые производные бензазепина |
MXPA06011167A (es) * | 2004-04-01 | 2007-01-25 | Eli Lilli And Company | Agentes del receptor h3 de histamina, preparacion y usos terapeuticos. |
JP4942654B2 (ja) | 2004-08-23 | 2012-05-30 | イーライ リリー アンド カンパニー | ヒスタミンh3受容体薬剤、製剤及び治療的使用 |
US20090170869A1 (en) | 2007-09-06 | 2009-07-02 | Desmond John Best | Piperazine derivative having affinity for the histamine h3 receptor |
EP2215058B1 (en) * | 2007-10-17 | 2011-11-23 | Sanofi | Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereof |
US7799816B2 (en) | 2008-02-04 | 2010-09-21 | Roche Palo Alto Llc | Imidazolinylmethyl aryl sulfonamide |
CN102046624A (zh) | 2008-03-31 | 2011-05-04 | 埃沃特克股份有限公司 | 作为组胺h3受体拮抗剂的四氢萘啶及其氮杂衍生物 |
US8691804B2 (en) | 2008-05-08 | 2014-04-08 | Evotec Ag | Azetidines and cyclobutanes as histamine H3 receptor antagonists |
-
2011
- 2011-06-07 CN CN201180069505.8A patent/CN103443093B/zh active Active
- 2011-06-07 US US14/000,362 patent/US9079888B2/en active Active
- 2011-06-07 JP JP2013554978A patent/JP5805792B2/ja active Active
- 2011-06-07 AP AP2013007088A patent/AP3340A/xx active
- 2011-06-07 KR KR1020137024919A patent/KR101554407B1/ko active IP Right Grant
- 2011-06-07 ME MEP-2015-151A patent/ME02212B/me unknown
- 2011-06-07 CA CA2827567A patent/CA2827567C/en active Active
- 2011-06-07 NZ NZ61456711A patent/NZ614567A/en unknown
- 2011-06-07 DK DK11749555.6T patent/DK2694492T3/en active
- 2011-06-07 SG SG2013063060A patent/SG192858A1/en unknown
- 2011-06-07 PT PT117495556T patent/PT2694492E/pt unknown
- 2011-06-07 EA EA201391211A patent/EA023260B1/ru unknown
- 2011-06-07 WO PCT/IN2011/000380 patent/WO2012114348A1/en active Application Filing
- 2011-06-07 BR BR112013021496-1A patent/BR112013021496B1/pt active IP Right Grant
- 2011-06-07 ES ES11749555.6T patent/ES2548284T3/es active Active
- 2011-06-07 PL PL11749555T patent/PL2694492T3/pl unknown
- 2011-06-07 MX MX2013009683A patent/MX339858B/es active IP Right Grant
- 2011-06-07 HU HUE11749555A patent/HUE025163T2/en unknown
- 2011-06-07 RS RS20150610A patent/RS54248B1/en unknown
- 2011-06-07 EP EP11749555.6A patent/EP2694492B1/en active Active
- 2011-06-07 AU AU2011360550A patent/AU2011360550B2/en active Active
- 2011-06-07 SI SI201130601T patent/SI2694492T1/sl unknown
-
2013
- 2013-08-18 IL IL228019A patent/IL228019A/en active IP Right Grant
- 2013-08-22 ZA ZA2013/06328A patent/ZA201306328B/en unknown
-
2014
- 2014-01-20 HK HK14100570.2A patent/HK1187613A1/xx unknown
-
2015
- 2015-09-23 HR HRP20151003TT patent/HRP20151003T1/hr unknown
- 2015-09-28 CY CY20151100859T patent/CY1116721T1/el unknown
- 2015-10-02 SM SM201500238T patent/SMT201500238B/xx unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100048580A1 (en) * | 2004-04-01 | 2010-02-25 | Lisa Selsam Beavers | Histamine h3 receptor agents, preparation and therapeutic uses |
WO2010045306A2 (en) * | 2008-10-16 | 2010-04-22 | Schering Corporation | Azine derivatives and methods of use thereof |
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