AP3074A - Haloalkyl heteroaryl benzamide compounds - Google Patents
Haloalkyl heteroaryl benzamide compoundsInfo
- Publication number
- AP3074A AP3074A AP2011006015A AP2011006015A AP3074A AP 3074 A AP3074 A AP 3074A AP 2011006015 A AP2011006015 A AP 2011006015A AP 2011006015 A AP2011006015 A AP 2011006015A AP 3074 A AP3074 A AP 3074A
- Authority
- AP
- ARIPO
- Prior art keywords
- benzamide compounds
- haloalkyl heteroaryl
- heteroaryl benzamide
- haloalkyl
- compounds
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/4196—1,2,4-Triazoles
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA021587B1 (ru) | 2009-05-12 | 2015-07-30 | РОМАРК ЛЭБОРЕТЕРИЗ Эл. Си. | Соединения галогеналкилгетероарилбензамида |
CA2968113C (en) * | 2009-06-26 | 2019-05-14 | Romark Laboratories L.C. | Compounds and methods for treating influenza |
ES2588999T3 (es) | 2011-03-22 | 2016-11-08 | Bayer Intellectual Property Gmbh | Amidas del ácido N-(1,3,4-oxadiazol-2-il)arilcarboxílico y su uso como herbicidas |
JP6078065B2 (ja) * | 2011-08-03 | 2017-02-08 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | N−(テトラゾール−5−イル)アリールカルボキサミド類及びn−(トリアゾール−5−イル)アリールカルボキサミド類並びに除草剤としてのそれらの使用 |
US9056867B2 (en) | 2011-09-16 | 2015-06-16 | Novartis Ag | N-substituted heterocyclyl carboxamides |
US9758494B2 (en) | 2012-12-06 | 2017-09-12 | Bayer Cropscience Ag | N-(oxazol-2-yl)-aryl-carboxylic acid amides and use thereof as herbicides |
SG11201504740UA (en) * | 2012-12-27 | 2015-07-30 | Univ Drexel | Novel antiviral agents against hbv infection |
JP6371077B2 (ja) * | 2014-02-25 | 2018-08-08 | 国立大学法人佐賀大学 | ジフルオロメチル基含有化合物及びその用途 |
EP3140298A1 (en) | 2014-05-07 | 2017-03-15 | Pfizer Inc. | Tropomyosin-related kinase inhibitors |
MX2017006083A (es) | 2014-11-11 | 2017-11-08 | Romark Laboratories Lc | Composicones y metodos de tratamiento con profarmacos de tizoxanida, un analogo o sal de la misma. |
US10071997B2 (en) | 2014-12-01 | 2018-09-11 | Syngenta Participations Ag | Pesticidally active amide heterocyclic derivatives with sulphur containing substituents |
JP6904970B2 (ja) * | 2016-03-07 | 2021-07-21 | エナンタ ファーマシューティカルズ インコーポレイテッド | B型肝炎抗ウイルス剤 |
EA202091849A1 (ru) * | 2016-03-31 | 2020-12-11 | Ромарк Лабораториз Л.С. | Тиазолидные соединения для лечения вирусных инфекций |
SG11201808402RA (en) | 2016-04-11 | 2018-10-30 | Genfit | Methods of treatment for cholestatic and fibrotic diseases |
BR112019012822A2 (pt) | 2016-12-22 | 2019-11-26 | Bayer Ag | 1,2,4-tiadiazolilpirrolonas e 1,2,4-tiadiazolil-hidantoínas e sais das mesmas e uso das mesmas como herbicidas |
WO2018195035A1 (en) | 2017-04-18 | 2018-10-25 | Romark Laboratories L.C. | Inhibition of protein disulfide-isomerase a3 |
TWI811236B (zh) | 2017-08-28 | 2023-08-11 | 美商因那塔製藥公司 | B型肝炎抗病毒試劑 |
MA53983A (fr) | 2018-10-22 | 2021-12-15 | Assembly Biosciences Inc | Composés d'hétéroaryle carboxamide à 5 chaînons pour le traitement du vhb |
UY38483A (es) | 2018-11-21 | 2020-06-30 | Enanta Pharm Inc | Heterociclos funcionalizados como agentes antivirales |
WO2021016543A1 (en) * | 2019-07-25 | 2021-01-28 | Romark Laboratories L.C. | Antiviral combinations of thiazolide compounds |
US20230077704A1 (en) * | 2020-01-21 | 2023-03-16 | Academy Of Military Medical Sciences | Application of nitazoxanide and active form thereof, tizoxanide, in treatment of sars-cov-2 infection |
CN111187215B (zh) * | 2020-01-21 | 2023-02-24 | 西北农林科技大学 | 含氟吡唑酰胺类衍生物、制备方法及其应用 |
US20230241037A1 (en) * | 2020-03-09 | 2023-08-03 | 1Globe Health Institute, Nanjing | Cross-linked medication for treatment of coronaviral infection and method of treatment |
US11802125B2 (en) | 2020-03-16 | 2023-10-31 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
CN113398125B (zh) * | 2020-03-16 | 2024-05-03 | 绍兴君科臻元医药科技有限公司 | 替唑尼特药物组合物及其医药用途 |
JP2023537237A (ja) | 2020-07-20 | 2023-08-31 | ロマーク ラボラトリーズ,リミティド カンパニー | チゾキサニドおよび2-ヒドロキシ-n-(5-クロロ-1,3-チアゾル-2-イル)ベンズアミド(rm-4848)とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびn-メチルピペラジンの結晶塩 |
AU2021333566A1 (en) | 2020-08-24 | 2023-03-16 | Romark Laboratories L.C. | Use of thiazolides against coronaviruses |
WO2022109148A1 (en) * | 2020-11-18 | 2022-05-27 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Small molecule inhibitors of sars-cov-2 infections |
WO2022130406A1 (en) * | 2020-12-15 | 2022-06-23 | Cipla Limited | Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease |
CN116003323B (zh) * | 2023-02-14 | 2023-12-08 | 西北农林科技大学 | 含氟吡唑苯乙酰胺类衍生物及其应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080097106A1 (en) * | 2004-09-09 | 2008-04-24 | Romark Laboratories L.C. . | Halogenated benzamide derivatives |
US20090036467A1 (en) * | 2007-08-03 | 2009-02-05 | Romark Laboratories L.C. | Alkylsulfonyl-substituted thiazolide compounds |
Family Cites Families (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1177206A (en) | 1967-11-28 | 1970-01-07 | Pfizer & Co C | Lung Antiviral Factor |
GB1437800A (en) | 1973-08-08 | 1976-06-03 | Phavic Sprl | Derivatives of 2-benzamido-5-nitro-thiazoles |
US4337081A (en) * | 1979-01-23 | 1982-06-29 | Olin Corporation | 5-Amido-3-trihalomethyl-1,2,4-thiadiazoles and their use as herbicides |
US4343945A (en) * | 1979-01-23 | 1982-08-10 | Olin Corporation | 5-Benzamido-3-trichloromethyl-1,2,4-thiadiazoles and their use as herbicides, fungicides and insecticides |
SU910628A1 (ru) | 1980-04-22 | 1982-03-07 | Гродненский государственный медицинский институт | Способ получени 2-ациламинотиазолов |
JPS56158703A (en) * | 1980-05-10 | 1981-12-07 | Sankyo Co Ltd | Fungicide |
US4416683A (en) * | 1980-09-16 | 1983-11-22 | Eli Lilly And Company | Benzamides, compositions and agricultural method |
MA19269A1 (fr) * | 1980-09-16 | 1982-04-01 | Lilly Co Eli | Perfectionnement relatif a des derives de n-arylbenzamides . |
JPS649978A (en) | 1987-07-02 | 1989-01-13 | Shionogi & Co | Perfluoroalkylisoxazole derivative |
US4874864A (en) | 1988-05-24 | 1989-10-17 | Pfizer Inc. | Benzamide protease inhibitors |
US5169846A (en) | 1989-10-12 | 1992-12-08 | Crooks Michael J | Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators |
DK0740650T3 (da) | 1994-01-28 | 2004-09-27 | Univ Kentucky Res Found | Codrugs som metode til styret transport af lægemiddel |
DK0755386T3 (da) * | 1994-04-13 | 2002-08-26 | Romark Lab Lc | Benzamid-derivater, sammensætninger indeholdende nævnte derivat og anvendelse deraf |
US5578621A (en) | 1994-09-08 | 1996-11-26 | Romark Lab Lc | Benzamide derivatives |
MX9604483A (es) | 1994-09-08 | 1998-02-28 | Jean-Francois Rossignol | Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas. |
US5968961A (en) | 1997-05-07 | 1999-10-19 | Romark Laboratories, L.C. | Pharmaceutical compositions of tizoxanide and nitazoxanide |
KR100426657B1 (ko) * | 1997-05-07 | 2004-04-13 | 로마크 레버러토리즈, 엘.씨. | 티족사나이드 및 니타족사나이드의 약제학적 조성물 |
GB9725298D0 (en) * | 1997-11-28 | 1998-01-28 | Zeneca Ltd | Insecticidal thiazole derivatives |
DK1095016T3 (da) | 1998-07-08 | 2006-03-13 | Sanofi Aventis Deutschland | Svovlsubstituerede sulfonylaminocarboxylsyre-N-arylamider, deres fremstilling, deres anvendelse og farmaceutiske præparater omfattende dem |
GB9823871D0 (en) | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
US6849254B1 (en) | 1999-04-19 | 2005-02-01 | Schering Corporation | HCV combination therapy |
US6136835A (en) | 1999-05-17 | 2000-10-24 | The Procter & Gamble Company | Methods of treatment for viral infections |
JP4405726B2 (ja) * | 2000-12-21 | 2010-01-27 | ブリストル−マイヤーズ スクイブ カンパニー | Tecファミリーチロシンキナーゼのチアゾリルインヒビター |
ATE315555T1 (de) * | 2001-05-11 | 2006-02-15 | Pfizer Prod Inc | Thiazolderivate und ihre verwendung als cdk- inhibitoren |
WO2002092584A1 (fr) * | 2001-05-14 | 2002-11-21 | Nihon Nohyaku Co., Ltd. | Derives du thiadiazole, pesticides a usage agricole et horticole, et leurs utilisations |
SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
JP2003335680A (ja) | 2002-05-21 | 2003-11-25 | Otsuka Pharmaceut Factory Inc | Acat−1阻害剤 |
EP1510207A4 (en) * | 2002-06-05 | 2008-12-31 | Inst Med Molecular Design Inc | THERAPEUTIC MEDICAMENT AGAINST DIABETES |
WO2004028471A2 (en) | 2002-09-28 | 2004-04-08 | Massachusetts Institute Of Technology | Influenza therapeutic |
US20040242518A1 (en) | 2002-09-28 | 2004-12-02 | Massachusetts Institute Of Technology | Influenza therapeutic |
US6737382B1 (en) * | 2002-10-23 | 2004-05-18 | Nippon Soda Co. Ltd. | Insecticidal aminothiazole derivatives |
US7807174B2 (en) | 2002-11-22 | 2010-10-05 | Nexbio, Inc. | Class of therapeutic protein based molecules |
RU2330030C2 (ru) | 2003-02-26 | 2008-07-27 | Баниу Фармасьютикал Ко., Лтд. | Производные гетероарилкарбамоилбензола |
US7285576B2 (en) | 2003-03-12 | 2007-10-23 | 3M Innovative Properties Co. | Absorbent polymer compositions, medical articles, and methods |
JP2006521345A (ja) * | 2003-03-28 | 2006-09-21 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | ニコチン性アセチルコリン受容体の正のアロステリック調節剤 |
KR20060054308A (ko) * | 2003-07-16 | 2006-05-22 | 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 | 피부 색소침착의 치료제 |
US20050090506A1 (en) | 2003-10-24 | 2005-04-28 | Nippon Soda Co., Ltd. | Insecticidal perfluoroalkylthiazole derivatives |
US7683097B2 (en) * | 2004-05-27 | 2010-03-23 | Propharmacon Inc. | Topoisomerase inhibitors |
US20060194853A1 (en) * | 2004-10-08 | 2006-08-31 | Rossignol Jean F | Alkyl benzamides |
US8357664B2 (en) | 2004-10-26 | 2013-01-22 | Avi Biopharma, Inc. | Antisense antiviral compound and method for treating influenza viral infection |
EP2047850A3 (en) | 2005-04-12 | 2009-07-29 | Romark Laboratories, L.C. | Methods for treating diseases through inhibition of the function of molecular chaperones such as protein disulfide isomerases , pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents |
EA200702445A1 (ru) | 2005-05-09 | 2008-04-28 | Ачиллион Фармасьютикалз, Инк. | Соединения тиазола и способы их применения |
US8541457B2 (en) | 2005-06-03 | 2013-09-24 | Xenon Pharmaceuticals Inc. | Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors |
TW200711649A (en) | 2005-06-17 | 2007-04-01 | Combinatorx Inc | Combination therapy for the treatment of immunoinflammatory disorders |
KR101363278B1 (ko) | 2005-06-27 | 2014-02-21 | 엑셀리시스 페이턴트 컴퍼니 엘엘씨 | 이미다졸계 lxr 변조제 |
WO2007008541A2 (en) | 2005-07-08 | 2007-01-18 | Kalypsys, Inc. | Cellular cholesterol absorption modifiers |
RU2008107868A (ru) | 2005-08-02 | 2009-09-10 | Айрм Ллк (Bm) | Соединения и композиции в качестве ингибиторов протеинкиназ |
JP2009521479A (ja) * | 2005-12-21 | 2009-06-04 | アボット・ラボラトリーズ | 抗ウイルス化合物 |
ZA200806310B (en) * | 2006-01-09 | 2009-12-30 | Romark Lab Lc | Viral hepatitis treatment |
JP2009535318A (ja) | 2006-04-28 | 2009-10-01 | トランステック ファーマ,インコーポレイティド | ベンズアミドグルコキナーゼ活性化剤 |
BRPI0712720A2 (pt) * | 2006-05-31 | 2012-11-20 | Abbott Lab | compostos tiazàis como ligantes do receptor canabinàide e usos dos mesmos |
JP5153773B2 (ja) * | 2006-07-07 | 2013-02-27 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | フェニル置換ヘテロアリール誘導体及び抗癌剤としてのその使用 |
WO2008033466A2 (en) | 2006-09-14 | 2008-03-20 | Combinatorx (Singapore) Pre. Ltd. | Compositions and methods for treatment of viral diseases |
JP2010511728A (ja) * | 2006-12-05 | 2010-04-15 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | Il−8受容体アンタゴニスト |
WO2009001214A2 (en) * | 2007-06-28 | 2008-12-31 | Pfizer Products Inc. | Thieno[2,3-d]pyrimidin-4(3h)-one, isoxazolo[5,4-d]pyrimidin-4(5h)-one and isothiazolo[5,4-d]pyrimidin-4(5h)-one derivatives as calcium receptor antagonists |
WO2009065096A1 (en) * | 2007-11-16 | 2009-05-22 | University Of Medicine And Dentistry Of New Jersey | Mechanism-based small-molecule parasite inhibitors |
US20100009970A1 (en) | 2008-03-19 | 2010-01-14 | Combinatorx (Singapore) Pte. Ltd. | Compositions and methods for treatment of viral diseases |
US20100081713A1 (en) | 2008-03-19 | 2010-04-01 | CombinatoRx, (Singapore) Pte. Ltd. | Compositions and methods for treating viral infections |
WO2009152356A2 (en) * | 2008-06-11 | 2009-12-17 | Irm Llc | Compounds and compositions useful for the treatment of malaria |
TW201014860A (en) * | 2008-09-08 | 2010-04-16 | Boehringer Ingelheim Int | New chemical compounds |
UY32138A (es) * | 2008-09-25 | 2010-04-30 | Boehringer Ingelheim Int | Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables |
US20110224136A1 (en) * | 2008-11-19 | 2011-09-15 | Ting Pauline C | Inhibitors of diacylglycerol acyltransferase |
WO2010107736A2 (en) | 2009-03-20 | 2010-09-23 | University Of Virginia Patent Foundation | Broad spectrum benzothiophene-nitrothiazolide and other antimicrobials |
EA021587B1 (ru) | 2009-05-12 | 2015-07-30 | РОМАРК ЛЭБОРЕТЕРИЗ Эл. Си. | Соединения галогеналкилгетероарилбензамида |
CA2968113C (en) | 2009-06-26 | 2019-05-14 | Romark Laboratories L.C. | Compounds and methods for treating influenza |
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2010
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- 2010-05-11 AU AU2010247816A patent/AU2010247816B2/en not_active Ceased
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- 2010-05-11 CN CN201610225952.2A patent/CN105853415A/zh active Pending
- 2010-05-11 BR BRPI1010547-6A patent/BRPI1010547A2/pt not_active Application Discontinuation
- 2010-05-11 EP EP16167043.5A patent/EP3078377A3/en not_active Withdrawn
- 2010-05-11 SG SG10201402281WA patent/SG10201402281WA/en unknown
- 2010-05-11 MX MX2011012040A patent/MX337460B/es active IP Right Grant
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2014
- 2014-08-05 US US14/451,637 patent/US9126992B2/en not_active Ceased
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2015
- 2015-07-03 JP JP2015134747A patent/JP6193922B2/ja active Active
- 2015-07-27 IL IL240167A patent/IL240167A0/en unknown
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2016
- 2016-04-18 AU AU2016202439A patent/AU2016202439B2/en not_active Ceased
- 2016-05-17 US US15/156,580 patent/USRE46724E1/en active Active
- 2016-09-22 HK HK16111122.0A patent/HK1223819A1/zh unknown
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2018
- 2018-01-08 US US15/864,411 patent/USRE47786E1/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080097106A1 (en) * | 2004-09-09 | 2008-04-24 | Romark Laboratories L.C. . | Halogenated benzamide derivatives |
US20090036467A1 (en) * | 2007-08-03 | 2009-02-05 | Romark Laboratories L.C. | Alkylsulfonyl-substituted thiazolide compounds |
Non-Patent Citations (1)
Title |
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Tellinghuisen et al., "Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase," Nature Letters, 2005, 435:374-379 * |
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