AP2670A - Antibacterial quinoline derivatives - Google Patents
Antibacterial quinoline derivativesInfo
- Publication number
- AP2670A AP2670A AP2009004871A AP2009004871A AP2670A AP 2670 A AP2670 A AP 2670A AP 2009004871 A AP2009004871 A AP 2009004871A AP 2009004871 A AP2009004871 A AP 2009004871A AP 2670 A AP2670 A AP 2670A
- Authority
- AP
- ARIPO
- Prior art keywords
- quinoline derivatives
- antibacterial quinoline
- antibacterial
- derivatives
- quinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125510 | 2006-12-06 | ||
| PCT/EP2007/063314 WO2008068268A1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP2009004871A0 AP2009004871A0 (en) | 2009-06-30 |
| AP2670A true AP2670A (en) | 2013-05-15 |
Family
ID=37909392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2009004871A AP2670A (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US8293732B2 (ru) |
| EP (1) | EP2099760B1 (ru) |
| JP (1) | JP5466012B2 (ru) |
| KR (3) | KR101908350B1 (ru) |
| CN (1) | CN101547905B (ru) |
| AP (1) | AP2670A (ru) |
| AR (1) | AR064147A1 (ru) |
| BR (1) | BRPI0719939B8 (ru) |
| CA (1) | CA2668517C (ru) |
| CL (1) | CL2007003515A1 (ru) |
| CY (1) | CY1114384T1 (ru) |
| DK (1) | DK2099760T3 (ru) |
| EA (1) | EA022344B1 (ru) |
| ES (1) | ES2407824T3 (ru) |
| HK (1) | HK1137433A1 (ru) |
| HR (1) | HRP20130372T1 (ru) |
| IL (2) | IL199078A (ru) |
| JO (1) | JO2970B1 (ru) |
| ME (1) | ME01521B (ru) |
| MX (1) | MX2009005979A (ru) |
| MY (1) | MY150411A (ru) |
| NO (1) | NO342095B1 (ru) |
| NZ (1) | NZ577128A (ru) |
| PL (1) | PL2099760T3 (ru) |
| PT (1) | PT2099760E (ru) |
| RS (1) | RS52753B (ru) |
| SG (1) | SG10201405650SA (ru) |
| SI (1) | SI2099760T1 (ru) |
| TW (1) | TWI396536B (ru) |
| UA (1) | UA101306C2 (ru) |
| WO (1) | WO2008068268A1 (ru) |
| ZA (1) | ZA200903946B (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2970B1 (en) * | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
| WO2013160431A1 (en) | 2012-04-27 | 2013-10-31 | Janssen Pharmaceutica Nv | Antibacterial quinoline derivatives |
| DK2841425T3 (en) | 2012-04-27 | 2016-06-27 | Janssen Pharmaceutica Nv | ANTIBACTERIAL QUINOLIN DERIVATIVES |
| BR112018067922B1 (pt) * | 2016-03-07 | 2024-02-06 | The Global Alliance For Tb Drug Development, Inc | Compostos antibacterianos, usos dos mesmos e composições farmacêuticas |
| WO2018048882A1 (en) | 2016-09-06 | 2018-03-15 | The Research Foundation For The State University Of New York | Positron imaging tomography imaging agent composition and method for bacterial infection |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0936866A4 (en) | 1996-10-28 | 2001-04-11 | Dept Of The Army Us Government | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING ANTIBIOTIC RESIST INFECTIONS |
| US6103905A (en) | 1997-06-19 | 2000-08-15 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| SI2301544T1 (sl) * | 2002-07-25 | 2013-01-31 | Janssen Pharmaceutica, N.V. | Derivati kinolina kot vmesne spojine za mikobakterijske inhibitorje |
| EP1711492B1 (en) | 2004-01-23 | 2008-04-16 | Janssen Pharmaceutica N.V. | Substituted quinolines and their use as mycobacterial inhibitors |
| DE602005016890D1 (de) | 2004-01-23 | 2009-11-12 | Janssen Pharmaceutica Nv | Chinolinderivate und ihre verwendung als mycobakterielle inhibitoren |
| EA011572B9 (ru) | 2004-01-29 | 2018-01-31 | Янссен Фармацевтика Н.В. | Производные хинолина для применения в качестве микобактериальных ингибиторов |
| MXPA06013888A (es) * | 2004-05-28 | 2007-01-26 | Janssen Pharmaceutica Nv | Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a los farmacos. |
| CA2579971C (en) | 2004-09-28 | 2018-02-13 | Janssen Pharmaceutica N.V. | A bacterial atp synthase binding domain |
| EE05394B1 (et) * | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
| CA2528849C (en) | 2005-06-08 | 2014-01-14 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
| AP2547A (en) | 2005-06-28 | 2012-12-26 | Janssen Pharmaceutica Nv | Quinoline derivatives as antibacterial agents |
| JO2752B1 (en) | 2005-06-28 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| JO2683B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
| JO2970B1 (en) * | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
-
2007
- 2007-11-29 JO JO2007505A patent/JO2970B1/en active
- 2007-12-04 NZ NZ577128A patent/NZ577128A/en unknown
- 2007-12-04 CN CN200780044895.7A patent/CN101547905B/zh active Active
- 2007-12-04 MY MYPI20092286 patent/MY150411A/en unknown
- 2007-12-04 PL PL07847812T patent/PL2099760T3/pl unknown
- 2007-12-04 EA EA200970536A patent/EA022344B1/ru unknown
- 2007-12-04 ES ES07847812T patent/ES2407824T3/es active Active
- 2007-12-04 SI SI200731214T patent/SI2099760T1/sl unknown
- 2007-12-04 RS RS20130165A patent/RS52753B/en unknown
- 2007-12-04 ME MEP-2013-43A patent/ME01521B/me unknown
- 2007-12-04 KR KR1020157031291A patent/KR101908350B1/ko active IP Right Grant
- 2007-12-04 KR KR1020167037101A patent/KR20170003741A/ko not_active Application Discontinuation
- 2007-12-04 DK DK07847812.0T patent/DK2099760T3/da active
- 2007-12-04 KR KR1020097012242A patent/KR101574642B1/ko active Application Filing
- 2007-12-04 US US12/516,249 patent/US8293732B2/en active Active
- 2007-12-04 JP JP2009539739A patent/JP5466012B2/ja active Active
- 2007-12-04 UA UAA200904217A patent/UA101306C2/ru unknown
- 2007-12-04 SG SG10201405650SA patent/SG10201405650SA/en unknown
- 2007-12-04 WO PCT/EP2007/063314 patent/WO2008068268A1/en active Application Filing
- 2007-12-04 MX MX2009005979A patent/MX2009005979A/es active IP Right Grant
- 2007-12-04 BR BRPI0719939A patent/BRPI0719939B8/pt active IP Right Grant
- 2007-12-04 CA CA2668517A patent/CA2668517C/en active Active
- 2007-12-04 AP AP2009004871A patent/AP2670A/xx active
- 2007-12-04 PT PT78478120T patent/PT2099760E/pt unknown
- 2007-12-04 EP EP07847812A patent/EP2099760B1/en active Active
- 2007-12-05 CL CL200703515A patent/CL2007003515A1/es unknown
- 2007-12-05 TW TW096146215A patent/TWI396536B/zh active
- 2007-12-05 AR ARP070105440A patent/AR064147A1/es unknown
-
2009
- 2009-06-02 IL IL199078A patent/IL199078A/en active IP Right Grant
- 2009-06-05 ZA ZA200903946A patent/ZA200903946B/xx unknown
- 2009-07-06 NO NO20092536A patent/NO342095B1/no unknown
-
2010
- 2010-02-01 HK HK10101095.0A patent/HK1137433A1/xx unknown
-
2013
- 2013-04-26 HR HRP20130372TT patent/HRP20130372T1/hr unknown
- 2013-05-17 CY CY20131100403T patent/CY1114384T1/el unknown
-
2015
- 2015-09-10 IL IL241548A patent/IL241548B/en active IP Right Grant
Also Published As
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