AP2009004945A0 - New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
AP2009004945A0
AP2009004945A0 AP2009004945A AP2009004945A AP2009004945A0 AP 2009004945 A0 AP2009004945 A0 AP 2009004945A0 AP 2009004945 A AP2009004945 A AP 2009004945A AP 2009004945 A AP2009004945 A AP 2009004945A AP 2009004945 A0 AP2009004945 A0 AP 2009004945A0
Authority
AP
ARIPO
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
tricyclic compounds
new tricyclic
Prior art date
Application number
AP2009004945A
Other languages
English (en)
Inventor
John Hickman
Patrick Casara
Olivier Geneste
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of AP2009004945A0 publication Critical patent/AP2009004945A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AP2009004945A 2007-02-02 2008-02-01 New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them AP2009004945A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0700741A FR2912145B1 (fr) 2007-02-02 2007-02-02 Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2008/000121 WO2008110691A1 (fr) 2007-02-02 2008-02-01 Nouveaux derives tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
AP2009004945A0 true AP2009004945A0 (en) 2009-08-31

Family

ID=38219469

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2009004945A AP2009004945A0 (en) 2007-02-02 2008-02-01 New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (45)

Country Link
US (1) US20080188460A1 (es)
EP (1) EP1953161B1 (es)
JP (1) JP2008266296A (es)
KR (1) KR100997027B1 (es)
CN (1) CN101270120A (es)
AP (1) AP2009004945A0 (es)
AR (1) AR065131A1 (es)
AT (1) ATE440842T1 (es)
AU (1) AU2008200499A1 (es)
BR (1) BRPI0800988A2 (es)
CA (1) CA2619897C (es)
CL (1) CL2008000318A1 (es)
CO (1) CO6230990A2 (es)
CR (1) CR10953A (es)
CY (1) CY1109637T1 (es)
DE (1) DE602008000104D1 (es)
DK (1) DK1953161T3 (es)
EA (1) EA014672B1 (es)
EC (1) ECSP099546A (es)
ES (1) ES2332337T3 (es)
FR (1) FR2912145B1 (es)
GE (1) GEP20115186B (es)
GT (1) GT200900217A (es)
HR (1) HRP20090565T1 (es)
IL (1) IL200128A0 (es)
JO (1) JO2616B1 (es)
MA (1) MA29725B1 (es)
MX (1) MX2008001504A (es)
MY (1) MY144633A (es)
NI (1) NI200900147A (es)
NZ (1) NZ565643A (es)
PA (1) PA8768301A1 (es)
PE (1) PE20081703A1 (es)
PL (1) PL1953161T3 (es)
PT (1) PT1953161E (es)
RS (1) RS51133B (es)
SA (1) SA08290043B1 (es)
SG (1) SG144892A1 (es)
SI (1) SI1953161T1 (es)
SV (1) SV2009003348A (es)
TN (1) TN2009000307A1 (es)
TW (1) TW200838532A (es)
UA (1) UA90726C2 (es)
WO (1) WO2008110691A1 (es)
ZA (1) ZA200801103B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101506147B (zh) 2006-09-07 2012-03-21 霍夫曼-拉罗奇有限公司 用于制备snac(n-(8-[2-羟基苯甲酰基]-氨基)辛酸钠)的方法
FR2933983B1 (fr) * 2008-07-15 2010-08-27 Servier Lab Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CN102482292B (zh) * 2009-04-23 2017-07-18 Abbvie 公司 5‑ht受体的调节剂和其使用方法
US8518933B2 (en) * 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
US8546377B2 (en) * 2009-04-23 2013-10-01 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
CN102498111A (zh) * 2009-09-10 2012-06-13 诺瓦提斯公司 作为Bcl-2家族蛋白抑制剂用于癌症的治疗的磺酰胺化合物
CN102584744B (zh) * 2011-01-06 2015-07-01 上海药明康德新药开发有限公司 4-(4-((2-(4-氯苯基)-5,5-二甲基环己基-1-烯)甲基)哌嗪-1-基)苯甲酸的合成方法
CN104039797B (zh) 2011-10-12 2016-06-01 南京奥昭生物科技有限公司 作为细胞凋亡诱导剂的杂环分子
TWI620733B (zh) * 2013-05-21 2018-04-11 拜耳作物科學股份有限公司 製備特定肟類及肟醚類之改良方法
JOP20190239A1 (ar) 2017-04-19 2019-10-09 Neurocrine Biosciences Inc مركبات مثبطة لـ vmat2 وتركيبات منها

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899490A (en) * 1968-01-12 1975-08-12 Pfizer Hexahydro pyrazinoquinolines
DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
JP2000169475A (ja) * 1998-07-24 2000-06-20 Dai Ichi Seiyaku Co Ltd ピラゾ―ル誘導体およびその塩
US6180629B1 (en) * 1998-08-14 2001-01-30 Cell Pathways, Inc. [4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia
US6190629B1 (en) 1999-04-16 2001-02-20 Cbl Technologies, Inc. Organic acid scrubber and methods
US7919493B2 (en) * 2000-04-12 2011-04-05 Pharma Mar, S.A. Anititumoral ecteinascidin derivatives
MXPA03000906A (es) * 2000-07-31 2005-02-24 Hoffmann La Roche Derivados de piperazina.
DE60231230D1 (de) * 2001-11-03 2009-04-02 Astrazeneca Ab Quinazolin derivate als antitumor-mittel
EP1487449A4 (en) * 2001-12-21 2006-08-23 King Pharmaceuticals Res & Dev TYROSYL DERIVATIVES AND THEIR USE AS P2X7 RECEPTOR MODULATORS
FR2841243B1 (fr) * 2002-06-19 2004-08-20 Servier Lab Nouveaux derives de 3-(4-oxo-4h-chromen-2yl)-(1h)-quinolein- 4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2004055163A2 (en) * 2002-12-12 2004-07-01 Cytovia, Inc. Substituted 1-benzoyl-3-cyano-pyrrolo[1,2-a]quinolines
WO2005049593A2 (en) * 2003-11-13 2005-06-02 Abbott Laboratories N-acylsulfonamide apoptosis promoters
EP1714961B1 (en) * 2004-02-12 2015-12-09 Mitsubishi Tanabe Pharma Corporation Indazole compound and pharmaceutical use thereof
US7790712B2 (en) * 2005-03-17 2010-09-07 Boehringer Ingelheim Pharmaceutical, Inc. Substituted [1,4]diazepino[1,2-A]indoles and azepino[1,2-A]indoles as anti-cytokine inhibitors
US8119640B2 (en) * 2008-02-12 2012-02-21 The Board Of Trustees Of The Leland Stanford Junior University Hedgehog pathway antagonists methods of use

Also Published As

Publication number Publication date
IL200128A0 (en) 2010-04-15
KR100997027B1 (ko) 2010-11-25
ZA200801103B (en) 2008-12-31
SG144892A1 (en) 2008-08-28
NZ565643A (en) 2009-05-31
ECSP099546A (es) 2009-08-28
ATE440842T1 (de) 2009-09-15
BRPI0800988A2 (pt) 2008-11-25
NI200900147A (es) 2010-02-15
DE602008000104D1 (de) 2009-10-08
AR065131A1 (es) 2009-05-20
GT200900217A (es) 2011-09-14
JP2008266296A (ja) 2008-11-06
PT1953161E (pt) 2009-10-26
CR10953A (es) 2009-09-09
JO2616B1 (ar) 2011-11-01
EP1953161A1 (fr) 2008-08-06
FR2912145B1 (fr) 2009-03-06
PE20081703A1 (es) 2009-01-14
CY1109637T1 (el) 2014-08-13
US20080188460A1 (en) 2008-08-07
MY144633A (en) 2011-10-14
EA200800235A1 (ru) 2008-08-29
DK1953161T3 (da) 2009-11-30
GEP20115186B (en) 2011-03-25
TN2009000307A1 (fr) 2010-12-31
PA8768301A1 (es) 2008-11-19
CA2619897A1 (fr) 2008-08-02
SA08290043B1 (ar) 2011-06-22
MA29725B1 (fr) 2008-09-01
HRP20090565T1 (hr) 2009-12-31
SV2009003348A (es) 2010-02-01
KR20080072574A (ko) 2008-08-06
AU2008200499A1 (en) 2008-08-21
WO2008110691A1 (fr) 2008-09-18
MX2008001504A (es) 2009-02-24
RS51133B (sr) 2010-10-31
CA2619897C (fr) 2011-06-14
CN101270120A (zh) 2008-09-24
ES2332337T3 (es) 2010-02-02
FR2912145A1 (fr) 2008-08-08
EP1953161B1 (fr) 2009-08-26
TW200838532A (en) 2008-10-01
CO6230990A2 (es) 2010-12-20
UA90726C2 (ru) 2010-05-25
SI1953161T1 (sl) 2009-12-31
PL1953161T3 (pl) 2010-01-29
CL2008000318A1 (es) 2008-08-08
EA014672B1 (ru) 2010-12-30

Similar Documents

Publication Publication Date Title
SG138588A1 (en) New naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them
IL200128A0 (en) New tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them
AP3024A (en) New Diosmetin compounds, a process for their preparation and pharmaceutical compositions containing them
SG151172A1 (en) 1,2,4,5-tetrahydro-3h-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them
IL215016A0 (en) New benzothiadiazepine compounds, a process for their preparation and pharmaceutical compositions containing them
IL207183A0 (en) New dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them
HK1096386A1 (en) Indanyl-piperazine compounds, a process for their preparation and pharmaceutical compositions containing them
ZA200603810B (en) Phenylpyridylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them
HK1096097A1 (en) Phenylpyridylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them
HK1111403A1 (en) New naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them
ZA201000025B (en) New naphthalene compounds,a process for their preparation and pharmaceutical compositions containing them
IL206885A0 (en) New chromene compounds, a process for their preparation and pharmaceutical compositions containing them
ZA201000024B (en) New naphthalene compounds,a process for their preparation and pharmaceutical compositions containing them
AP2009004891A0 (en) New azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them
SG138590A1 (en) New naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them
ZA200800833B (en) New 1H-indole-pyridinecarboxamide and 1H-indolepiperidinecarboxamide compounds, a process for their preparation and pharmaceutical compositions containing them
ZA201106353B (en) Dihydrobenzoxathiazepine compounds,a process for their preparation and pharmaceutical compositions containing them
AP2010005304A0 (en) New 2-mercaptocyclopentanecarboxylic acid compounds, a process for their preparation and pharmaceutical compositions containing them
IL206884A0 (en) New piperidine compounds, a process for their preparation and pharmaceutical compositions containing them
ZA201203943B (en) New azabicyclo[3.1.0]hex-2-yl compounds,a process for their preparation and pharmaceutical compositions containing them
HK1119163A1 (en) Tetracyclic compounds, a process for their preparation and pharmaceutical compositions containing them
AP2010005327A0 (en) New chromene compounds, a process for their preparation and pharmaceutical compositions containing them.
AP2755A (en) New azabicyclo[3.2.0]hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them