AP2007004003A0 - N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors - Google Patents

N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors

Info

Publication number
AP2007004003A0
AP2007004003A0 AP2007004003A AP2007004003A AP2007004003A0 AP 2007004003 A0 AP2007004003 A0 AP 2007004003A0 AP 2007004003 A AP2007004003 A AP 2007004003A AP 2007004003 A AP2007004003 A AP 2007004003A AP 2007004003 A0 AP2007004003 A0 AP 2007004003A0
Authority
AP
ARIPO
Prior art keywords
monoamine
pyrrolidin
uptake inhibitors
benzamide derivatives
benzamide
Prior art date
Application number
AP2007004003A
Other languages
English (en)
Inventor
Paul Vincent Fish
Thomas Ryckmans
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AP2007004003A0 publication Critical patent/AP2007004003A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AP2007004003A 2004-11-23 2005-11-18 N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors AP2007004003A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0425766.3A GB0425766D0 (en) 2004-11-23 2004-11-23 Novel compounds
PCT/IB2005/003643 WO2006056884A1 (en) 2004-11-23 2005-11-18 N- [ (3s)- pyrrolidin-3-yl]- benzamide derivatives as monoamine re-uptake inhibitors

Publications (1)

Publication Number Publication Date
AP2007004003A0 true AP2007004003A0 (en) 2007-06-30

Family

ID=33548739

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2007004003A AP2007004003A0 (en) 2004-11-23 2005-11-18 N-[(3S)-pyrrolidin-3YL]-benzamide derivatives as monoamine re-uptake inhibitors

Country Status (26)

Country Link
EP (1) EP1817281A1 (ko)
JP (1) JP4233596B2 (ko)
KR (1) KR100886294B1 (ko)
CN (1) CN101065355A (ko)
AP (1) AP2007004003A0 (ko)
AR (1) AR052243A1 (ko)
AU (1) AU2005308534A1 (ko)
BR (1) BRPI0518486A2 (ko)
CA (1) CA2589258A1 (ko)
CR (1) CR9171A (ko)
EA (1) EA011217B1 (ko)
GB (1) GB0425766D0 (ko)
GT (1) GT200500337A (ko)
IL (1) IL183191A0 (ko)
MA (1) MA29038B1 (ko)
MX (1) MX2007006138A (ko)
NL (2) NL1030485C2 (ko)
NO (1) NO20072486L (ko)
PA (1) PA8653501A1 (ko)
PE (1) PE20061056A1 (ko)
SV (1) SV2006002311A (ko)
TN (1) TNSN07201A1 (ko)
TW (1) TWI300776B (ko)
UY (1) UY29224A1 (ko)
WO (1) WO2006056884A1 (ko)
ZA (1) ZA200703910B (ko)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH628885A5 (en) * 1978-01-01 1982-03-31 Anphar Sa Piperidine derivative
DK1638933T3 (da) * 2003-06-17 2008-07-28 Pfizer N-pyrrolidin-3-yl-amid-derivater som serotonin- og noradrenalin-genoptagelses inhibitorer
GB0314054D0 (en) * 2003-06-17 2003-07-23 Pfizer Ltd Amide derivatives as selective serotonin re-uptake inhibitors

Also Published As

Publication number Publication date
KR20070086599A (ko) 2007-08-27
NL1032760A1 (nl) 2006-12-13
SV2006002311A (es) 2006-09-14
NL1030485A1 (nl) 2006-05-24
GT200500337A (es) 2006-06-13
AU2005308534A1 (en) 2006-06-01
UY29224A1 (es) 2006-06-30
CN101065355A (zh) 2007-10-31
GB0425766D0 (en) 2004-12-22
KR100886294B1 (ko) 2009-03-04
PA8653501A1 (es) 2006-06-02
CA2589258A1 (en) 2006-06-01
EA011217B1 (ru) 2009-02-27
MX2007006138A (es) 2007-07-19
PE20061056A1 (es) 2006-11-08
NO20072486L (no) 2007-06-20
EA200700920A1 (ru) 2007-12-28
IL183191A0 (en) 2007-08-19
NL1030485C2 (nl) 2006-11-07
JP4233596B2 (ja) 2009-03-04
ZA200703910B (en) 2008-09-25
WO2006056884A1 (en) 2006-06-01
AR052243A1 (es) 2007-03-07
NL1032760C2 (nl) 2007-04-17
MA29038B1 (fr) 2007-11-01
TWI300776B (en) 2008-09-11
JP2008520646A (ja) 2008-06-19
TW200626543A (en) 2006-08-01
TNSN07201A1 (fr) 2008-11-21
EP1817281A1 (en) 2007-08-15
CR9171A (es) 2007-07-04
BRPI0518486A2 (pt) 2008-11-18

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