PA8653501A1 - Nuevos compuestos - Google Patents
Nuevos compuestosInfo
- Publication number
- PA8653501A1 PA8653501A1 PA20058653501A PA8653501A PA8653501A1 PA 8653501 A1 PA8653501 A1 PA 8653501A1 PA 20058653501 A PA20058653501 A PA 20058653501A PA 8653501 A PA8653501 A PA 8653501A PA 8653501 A1 PA8653501 A1 PA 8653501A1
- Authority
- PA
- Panama
- Prior art keywords
- rent
- alcoxi
- het
- members
- heterocicle
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
UN COMPUESTO DE FORMULA (l) Y SUS DERIVADOS FARMACEUTICA Y/O VETERINARIAMENTE ACEPTABLES, EN LA QUE R1, R2, R3 Y R20 SON CADA UNO INDEPENDIENTEMENTE H, CI, BR, F CF3, OCF3, ME O ET; R4 ES HET O CICLOALQUILO DE C3-7 OPCIONALMENTE SUBSTITUIDO CON ALQUILO DE C1-4, ALCOXI DE C1-4, ALCOXIALQUILO QUE CONTIENE DE 2 A 4 ATOMOS DE CARBONO, O S-(ALQUILO DE C1-4); A ES O O 1; Y HET ES UN HETEROCICLO NO AROMATICO DE 4, 5 O 6 MIEMBROS QUE CONTIENEN POR LO MENOS UN HETEROATOMO DE N, O ó S, OPCIONALMENTE CONDENSADO CON UN GRUPO CARBOCICLICO DE 5 O 6 MIEMBROS O UN SEGUNDO HETEROCICLO DE 4, 5 O 6 MIEMBROS QUE CONTIENE POR LO MENOS UN HETEROATOMO DE N O o S, EN EL QUE EL GRUPO HET ESTA OPCIONALMENTE SUBSTITUIDO POR LO MENOS CON UN SUBSTITUYENTE SELECCIONADO INDEPENDIENTEMENTE DE ALQUILO DE C1-8, ALCOXI DE C1-8, OH, HALO, CF3, OCF3, SCF3, HIDROXI-ALQUILO DE C1-6, ALCOXI DE C1-4-AQUILO DE C1-6 Y ALQUIL DE C1-4-S-ALQUILO DE C1-4; CON TAL DE QUE POR LO MENOS UNO DE R1,R2,Y R3 SEA DISTINTO DE H. LOS COMPUESTOS DE LA INVENCION EXHIBEN ACTIVIDAD COMO INHIBIDORES DE LA RECAPTACION TANTO DE SEROTONINA COMO DE NORADRENALINA Y POR LO TANTO TIENEN UTILIDAD EN VARIAS AREAS TERAPEUTICAS, POR EJEMPLO, INCONTINENCIA URINARIA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0425766.3A GB0425766D0 (en) | 2004-11-23 | 2004-11-23 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PA8653501A1 true PA8653501A1 (es) | 2006-06-02 |
Family
ID=33548739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PA20058653501A PA8653501A1 (es) | 2004-11-23 | 2005-11-23 | Nuevos compuestos |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1817281A1 (es) |
| JP (1) | JP4233596B2 (es) |
| KR (1) | KR100886294B1 (es) |
| CN (1) | CN101065355A (es) |
| AP (1) | AP2007004003A0 (es) |
| AR (1) | AR052243A1 (es) |
| AU (1) | AU2005308534A1 (es) |
| BR (1) | BRPI0518486A2 (es) |
| CA (1) | CA2589258A1 (es) |
| CR (1) | CR9171A (es) |
| EA (1) | EA011217B1 (es) |
| GB (1) | GB0425766D0 (es) |
| GT (1) | GT200500337A (es) |
| IL (1) | IL183191A0 (es) |
| MA (1) | MA29038B1 (es) |
| MX (1) | MX2007006138A (es) |
| NL (2) | NL1030485C2 (es) |
| NO (1) | NO20072486L (es) |
| PA (1) | PA8653501A1 (es) |
| PE (1) | PE20061056A1 (es) |
| SV (1) | SV2006002311A (es) |
| TN (1) | TNSN07201A1 (es) |
| TW (1) | TWI300776B (es) |
| UY (1) | UY29224A1 (es) |
| WO (1) | WO2006056884A1 (es) |
| ZA (1) | ZA200703910B (es) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH628885A5 (en) * | 1978-01-01 | 1982-03-31 | Anphar Sa | Piperidine derivative |
| SI1638933T1 (sl) * | 2003-06-17 | 2008-10-31 | Pfizer | Derivati N-pirolidin-3-il-amida kot inhibitorji ponovnega privzema serotonina in noradrenalina |
| GB0314054D0 (en) * | 2003-06-17 | 2003-07-23 | Pfizer Ltd | Amide derivatives as selective serotonin re-uptake inhibitors |
-
2004
- 2004-11-23 GB GBGB0425766.3A patent/GB0425766D0/en not_active Ceased
-
2005
- 2005-11-18 CN CNA2005800401025A patent/CN101065355A/zh active Pending
- 2005-11-18 WO PCT/IB2005/003643 patent/WO2006056884A1/en active Application Filing
- 2005-11-18 EA EA200700920A patent/EA011217B1/ru not_active IP Right Cessation
- 2005-11-18 AU AU2005308534A patent/AU2005308534A1/en not_active Abandoned
- 2005-11-18 AP AP2007004003A patent/AP2007004003A0/xx unknown
- 2005-11-18 MX MX2007006138A patent/MX2007006138A/es active IP Right Grant
- 2005-11-18 CA CA002589258A patent/CA2589258A1/en not_active Abandoned
- 2005-11-18 KR KR1020077014351A patent/KR100886294B1/ko not_active IP Right Cessation
- 2005-11-18 EP EP05808510A patent/EP1817281A1/en not_active Withdrawn
- 2005-11-18 JP JP2007542360A patent/JP4233596B2/ja not_active Expired - Fee Related
- 2005-11-18 BR BRPI0518486-0A patent/BRPI0518486A2/pt not_active IP Right Cessation
- 2005-11-21 PE PE2005001362A patent/PE20061056A1/es not_active Application Discontinuation
- 2005-11-21 AR ARP050104866A patent/AR052243A1/es not_active Application Discontinuation
- 2005-11-22 GT GT200500337A patent/GT200500337A/es unknown
- 2005-11-22 TW TW094140922A patent/TWI300776B/zh active
- 2005-11-22 NL NL1030485A patent/NL1030485C2/nl not_active IP Right Cessation
- 2005-11-22 UY UY29224A patent/UY29224A1/es not_active Application Discontinuation
- 2005-11-23 SV SV2005002311A patent/SV2006002311A/es unknown
- 2005-11-23 PA PA20058653501A patent/PA8653501A1/es unknown
-
2006
- 2006-10-27 NL NL1032760A patent/NL1032760C2/nl not_active IP Right Cessation
-
2007
- 2007-05-14 IL IL183191A patent/IL183191A0/en unknown
- 2007-05-15 ZA ZA200703910A patent/ZA200703910B/xx unknown
- 2007-05-15 NO NO20072486A patent/NO20072486L/no not_active Application Discontinuation
- 2007-05-22 TN TNP2007000201A patent/TNSN07201A1/fr unknown
- 2007-05-23 MA MA29935A patent/MA29038B1/fr unknown
- 2007-06-07 CR CR9171A patent/CR9171A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005308534A1 (en) | 2006-06-01 |
| UY29224A1 (es) | 2006-06-30 |
| KR20070086599A (ko) | 2007-08-27 |
| NO20072486L (no) | 2007-06-20 |
| EP1817281A1 (en) | 2007-08-15 |
| MA29038B1 (fr) | 2007-11-01 |
| TWI300776B (en) | 2008-09-11 |
| ZA200703910B (en) | 2008-09-25 |
| KR100886294B1 (ko) | 2009-03-04 |
| NL1030485A1 (nl) | 2006-05-24 |
| GB0425766D0 (en) | 2004-12-22 |
| CA2589258A1 (en) | 2006-06-01 |
| TNSN07201A1 (fr) | 2008-11-21 |
| AR052243A1 (es) | 2007-03-07 |
| JP4233596B2 (ja) | 2009-03-04 |
| NL1032760C2 (nl) | 2007-04-17 |
| TW200626543A (en) | 2006-08-01 |
| NL1030485C2 (nl) | 2006-11-07 |
| SV2006002311A (es) | 2006-09-14 |
| PE20061056A1 (es) | 2006-11-08 |
| JP2008520646A (ja) | 2008-06-19 |
| CR9171A (es) | 2007-07-04 |
| NL1032760A1 (nl) | 2006-12-13 |
| CN101065355A (zh) | 2007-10-31 |
| GT200500337A (es) | 2006-06-13 |
| BRPI0518486A2 (pt) | 2008-11-18 |
| AP2007004003A0 (en) | 2007-06-30 |
| IL183191A0 (en) | 2007-08-19 |
| EA200700920A1 (ru) | 2007-12-28 |
| EA011217B1 (ru) | 2009-02-27 |
| MX2007006138A (es) | 2007-07-19 |
| WO2006056884A1 (en) | 2006-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PA8605301A1 (es) | Nuevos compuestos | |
| NI200700270A (es) | Derivados benzodioxano y benzodioxolano y usos de los mismos | |
| ECSP066898A (es) | Antagonistas de cgrp seleccionados, procedimiento para su preparación así como su uso como medicamento | |
| GT200400092A (es) | Preparacion y uso de derivados de alquilarilo para el tratamiento de la obesidad | |
| EA200800514A1 (ru) | Замещённые 7-азаиндазолы, содержащие их композиции, способ получения и применения | |
| ECSP088638A (es) | Bencensulfonil-cromano, tiocromano, tetrahidronaftaleno e inhibidores de gamma secretasa relacionados | |
| UY28215A1 (es) | Quinazolinas utiles como moduladores de canales iónicos | |
| UY28026A1 (es) | 4-piperazinilbencenosulfonilindoles y usos de los mismos. | |
| PA8575401A1 (es) | Derivados de heteroarilamida benzocondensada de tienopiridinas utiles como agentes terapeuticos, composiciones farmaceuticas que incluyen a los mismos y metrodos para su uso | |
| AR074358A1 (es) | Derivados de pirazina como inhibidores de la fosfodiesterasa 10 | |
| DE602006006850D1 (de) | Als modulatoren von dopamin-d3-rezeptoren geeignete azabicyclo-(3,1,0)-hexan-derivate | |
| CR10327A (es) | "PIRIDIN(3-4-b) PIRAZINONAS" | |
| ECSP066671A (es) | Nuevos derivados de quinolina | |
| ECSP088870A (es) | Derivados de cicloalquilaminoacidos | |
| UY29246A1 (es) | Nuevos compuestos | |
| UY28848A1 (es) | Antagonistas de cgrp seleccionados, procedimientos para su preparación, y su empleo como medicamentos | |
| ECSP088194A (es) | Antagonistas de cgrp seleccionados, procedimientos para su preparación, así como su uso como medicamentos | |
| TW200716529A (en) | New compounds II | |
| UY31712A1 (es) | Nuevos derivados de diosmetina, su procedimiento de preparacion y las composiciones farmacéuticas que los contienen | |
| TW200800962A (en) | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | |
| UY27685A1 (es) | Indolil-urea derivados de tienopiridinas útiles como agentes antiangiogénicos, y procedimientos para su uso | |
| CO6270226A2 (es) | Nuevos compuestos espirociclicos como antagonistas de cgrp | |
| AR073043A1 (es) | Compuestos de azetidinas polisustituidos, composiciones farmaceuticas que los contienen, metodo de preparacion y uso de los mismos en el tratamiento de enfermedades respiratorias, metabolicas y del sistema nervioso central, entre otras. | |
| CR9499A (es) | Nuevos derivados de fenilpiridinilpiperazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
| CR10255A (es) | "nuevas composiciones terapéuticas para el tratamiento o la prevención de trastornos psicóticos" |