AP2006003759A0 - (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazoloÄ1,5-cÜÄ1,3Übenzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors - Google Patents

(1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazoloÄ1,5-cÜÄ1,3Übenzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors

Info

Publication number
AP2006003759A0
AP2006003759A0 AP2006003759A AP2006003759A AP2006003759A0 AP 2006003759 A0 AP2006003759 A0 AP 2006003759A0 AP 2006003759 A AP2006003759 A AP 2006003759A AP 2006003759 A AP2006003759 A AP 2006003759A AP 2006003759 A0 AP2006003759 A0 AP 2006003759A0
Authority
AP
ARIPO
Prior art keywords
phenyl
cüä1
aminocarbonyl
dihydro
viral replication
Prior art date
Application number
AP2006003759A
Other languages
English (en)
Inventor
Abdellah Tahri
Lieve Emma Jan Michiels
Dominique Louis Nest Surleraux
Van Koenraad Lodewijk Au Acker
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of AP2006003759A0 publication Critical patent/AP2006003759A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AP2006003759A 2004-05-04 2005-05-04 (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazoloÄ1,5-cÜÄ1,3Übenzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors AP2006003759A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04101913 2004-05-04
US60427504P 2004-08-25 2004-08-25
PCT/EP2005/052041 WO2005105810A2 (en) 2004-05-04 2005-05-04 (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazolo[1,5- c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as hiv viral replication inhibitors

Publications (1)

Publication Number Publication Date
AP2006003759A0 true AP2006003759A0 (en) 2006-10-31

Family

ID=35058129

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003759A AP2006003759A0 (en) 2004-05-04 2005-05-04 (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazoloÄ1,5-cÜÄ1,3Übenzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors

Country Status (20)

Country Link
US (1) US7326703B2 (ja)
EP (1) EP1778696B1 (ja)
JP (1) JP4929162B2 (ja)
KR (1) KR20070015547A (ja)
CN (1) CN1950380B (ja)
AP (1) AP2006003759A0 (ja)
AR (1) AR048650A1 (ja)
AT (1) ATE389660T1 (ja)
AU (1) AU2005238235B2 (ja)
BR (1) BRPI0510612A (ja)
CA (1) CA2563959C (ja)
DE (1) DE602005005490T2 (ja)
ES (1) ES2303244T3 (ja)
IL (1) IL178082A (ja)
MX (1) MXPA06012755A (ja)
NO (1) NO20065582L (ja)
PL (1) PL1778696T3 (ja)
RU (1) RU2382789C2 (ja)
WO (1) WO2005105810A2 (ja)
ZA (1) ZA200609178B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
TW200710091A (en) * 2005-04-11 2007-03-16 Tibotec Pharm Ltd (1,10B-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo [1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors
MX2008000984A (es) * 2005-07-22 2008-04-04 Progenics Pharm Inc Metodos para reducir la carga viral en pacientes infectados con vih-1.
AU2008267237A1 (en) * 2007-06-25 2008-12-31 Tibotec Pharmaceuticals Combination formulations comprising darunavir and etravirine
US8592487B2 (en) * 2007-10-26 2013-11-26 Concert Pharmaceuticals, Inc. Deuterated darunavir
WO2009134401A2 (en) * 2008-04-29 2009-11-05 Progenics Pharmaceuticals, Inc. Methods of inhibiting infection by diverse subtypes of drug-resistant hiv-1

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
DE4210939A1 (de) * 1992-04-02 1993-10-07 Bayer Ag Verwendung von 7-Oxo-7H-pyrido[1,2,3-de][1,4]benzoxacin-6-carbonsäuren und -estern als Arzneimittel
PH30929A (en) 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
RU2170082C2 (ru) 1993-10-01 2001-07-10 Астра Актиеболаг Способ обработки лекарственного средства, устройство для формирования лекарственного средства и лекарственное средство
CA2240161C (en) 1996-05-20 2005-05-24 Janssen Pharmaceutica N.V. Antifungal compositions with improved bioavailability
WO1998014436A1 (en) * 1996-10-02 1998-04-09 Dupont Pharmaceuticals Company 4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as hiv reverse transcriptase inhibitors and intermediates and processes for making the same
IL129575A (en) 1997-03-26 2004-06-20 Janssen Pharmaceutica Nv Pills with a core coated with a fungicide and polymer
WO1999059587A1 (en) * 1998-05-20 1999-11-25 Eli Lilly And Company Anti-viral compounds
CZ305099B6 (cs) * 2001-04-10 2015-05-06 Pfizer Inc. Derivát pyrazolu, způsoby a meziprodukty pro výrobu, farmaceutická kompozice s jeho obsahem a jeho lékařské aplikace, zejména k léčení infekcí HIV

Also Published As

Publication number Publication date
PL1778696T3 (pl) 2008-08-29
IL178082A (en) 2012-06-28
JP4929162B2 (ja) 2012-05-09
BRPI0510612A (pt) 2007-10-30
AR048650A1 (es) 2006-05-10
ES2303244T3 (es) 2008-08-01
US7326703B2 (en) 2008-02-05
AU2005238235B2 (en) 2011-07-07
CN1950380B (zh) 2010-12-08
CA2563959C (en) 2014-07-15
RU2006142705A (ru) 2008-06-20
EP1778696B1 (en) 2008-03-19
CN1950380A (zh) 2007-04-18
RU2382789C2 (ru) 2010-02-27
DE602005005490D1 (de) 2008-04-30
DE602005005490T2 (de) 2009-04-23
ZA200609178B (en) 2008-08-27
EP1778696A2 (en) 2007-05-02
IL178082A0 (en) 2006-12-31
AU2005238235A1 (en) 2005-11-10
US20070248624A1 (en) 2007-10-25
JP2007536346A (ja) 2007-12-13
WO2005105810A2 (en) 2005-11-10
ATE389660T1 (de) 2008-04-15
NO20065582L (no) 2006-12-04
MXPA06012755A (es) 2007-01-16
KR20070015547A (ko) 2007-02-05
CA2563959A1 (en) 2005-11-10
WO2005105810A3 (en) 2006-03-02

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