ZA989461B - Methods and compositions for the treatment of autoimmune disease using heat shock proteins - Google Patents
Methods and compositions for the treatment of autoimmune disease using heat shock proteinsInfo
- Publication number
- ZA989461B ZA989461B ZA989461A ZA989461A ZA989461B ZA 989461 B ZA989461 B ZA 989461B ZA 989461 A ZA989461 A ZA 989461A ZA 989461 A ZA989461 A ZA 989461A ZA 989461 B ZA989461 B ZA 989461B
- Authority
- ZA
- South Africa
- Prior art keywords
- compositions
- treatment
- methods
- autoimmune disease
- heat shock
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 title 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/951,789 US6007821A (en) | 1997-10-16 | 1997-10-16 | Method and compositions for the treatment of autoimmune disease using heat shock proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA989461B true ZA989461B (en) | 1999-04-21 |
Family
ID=25492154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA989461A ZA989461B (en) | 1997-10-16 | 1998-10-16 | Methods and compositions for the treatment of autoimmune disease using heat shock proteins |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6007821A (de) |
| EP (1) | EP1024701A4 (de) |
| JP (1) | JP2002514570A (de) |
| AU (1) | AU756472B2 (de) |
| CA (1) | CA2306062A1 (de) |
| WO (1) | WO1999018801A1 (de) |
| ZA (1) | ZA989461B (de) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837251A (en) * | 1995-09-13 | 1998-11-17 | Fordham University | Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases |
| US6455493B1 (en) | 1996-09-20 | 2002-09-24 | University Of New Mexico | Methods for using heat shock proteins |
| WO1998012208A1 (en) | 1996-09-20 | 1998-03-26 | The University Of New Mexico | Heat shock protein complexes |
| US7157089B1 (en) | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| IT1290828B1 (it) * | 1997-03-25 | 1998-12-11 | Zetesis Spa | Uso di proteine estraibili da organi animali per la preparazione di medicamenti per il trattamento di condizioni patologiche |
| US6319503B1 (en) | 1998-02-19 | 2001-11-20 | Proteinix Company | Heat shock fusion-based vaccine system |
| ATE231917T1 (de) * | 1997-08-05 | 2003-02-15 | Stressgen Biotechnologies Corp | Immunresponse gegen hpv antigene erregt von zusammensetzungen die ein hpv antigen und ein stressprotein enthalten oder einen expressionsvektor fähig zur expression dieser proteine |
| US20060121051A1 (en) * | 1998-02-19 | 2006-06-08 | Kenten John H | Heat shock fusion-based vaccine system |
| EP1829551B1 (de) * | 1998-02-20 | 2010-09-29 | University of Miami | Modifizierter Hitzeschockprotein-Antigenpeptid-Komplex |
| CN1367875A (zh) | 1999-07-08 | 2002-09-04 | 斯特思吉生物技术公司 | 活体外th1一样反应的诱导方法 |
| EP1076091A1 (de) * | 1999-08-09 | 2001-02-14 | Universite Catholique De Louvain | Arzneimittel für die Verhinderung und/oder Behandlung von Herzischämie, peripheren Gefässkrankheiten, Tumoren und Wunden |
| AU6636800A (en) * | 1999-08-13 | 2001-03-13 | Proteinix Company | Heat shock fusion-based vaccine system |
| US8465468B1 (en) * | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
| US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
| US20020156453A1 (en) * | 1999-10-14 | 2002-10-24 | Pettis Ronald J. | Method and device for reducing therapeutic dosage |
| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| US20030108957A1 (en) * | 2002-07-19 | 2003-06-12 | The Wistar Institute Of Anatomy And Biology | Biocidal molecules, macromolecular targets and methods of production and use |
| US6812205B2 (en) * | 2000-03-15 | 2004-11-02 | The Brigham & Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
| US7235649B2 (en) * | 2000-03-24 | 2007-06-26 | Duke University | Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same |
| US7179462B2 (en) * | 2000-06-02 | 2007-02-20 | University Of Connecticut Health Center | α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
| AU2001266694C1 (en) * | 2000-06-02 | 2005-09-01 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
| US7186515B1 (en) | 2000-06-02 | 2007-03-06 | University Of Connecticut Health Center | Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
| CN100441223C (zh) | 2000-06-26 | 2008-12-10 | 尼文塔生物制药公司 | 人乳头状瘤病毒治疗 |
| US20040175360A1 (en) * | 2000-06-29 | 2004-09-09 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
| JP4676048B2 (ja) * | 2000-07-10 | 2011-04-27 | 生化学工業株式会社 | 脱髄性疾患処置剤 |
| WO2002012281A2 (en) * | 2000-08-03 | 2002-02-14 | Johns Hopkins University | Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen |
| US7608683B2 (en) * | 2000-08-09 | 2009-10-27 | The Regents Of The University Of California | Stress proteins and peptides and methods of use thereof |
| US6989146B2 (en) * | 2000-08-09 | 2006-01-24 | The Regents Of The University Of California | Stress proteins and peptides and methods of use thereof |
| CN1107681C (zh) * | 2000-08-11 | 2003-05-07 | 中国科学院微生物研究所 | 乙肝病毒抗原多肽与热休克蛋白的复合物及其应用 |
| MXPA03003901A (es) | 2000-11-01 | 2004-09-10 | Univ California | Peptidos inmuno-moduladores derivados de proteinas choque termico y sus usos. |
| BR0206995A (pt) | 2001-02-05 | 2005-08-16 | Stressgen Biotechnologies Corp | Tratamento do vìrus da hepatite b |
| EP1381423A1 (de) * | 2001-04-13 | 2004-01-21 | Becton, Dickinson and Company | Verfahren und vorrichtung zur intradermale abgabe von substanzen für systemischer absorption |
| WO2002094259A1 (en) * | 2001-05-03 | 2002-11-28 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Compounds that inhibit hsp90 and stimulate hsp70 and hsp40, useful in the prevention or treatment of diseases associated with protein aggregation and amyloid formation |
| US20070129307A1 (en) * | 2001-06-22 | 2007-06-07 | The University Of British Columbia | Insulin epitopes for the treatment of type 1 diabetes |
| WO2003001204A2 (en) * | 2001-06-22 | 2003-01-03 | The University Of British Columbia | Type 1 diabetes diagnostics and therapeutics |
| BR0210628A (pt) | 2001-06-29 | 2004-08-10 | Becton Dickinson Co | Liberação intradérmica de vacinas e agentes terapêuticos genéticos via microcânula |
| EP1551957A4 (de) * | 2001-10-01 | 2007-01-24 | Univ Duke | Isoliertes polypeptid der grp94-ligandenbindungsdomäne und dafür codierende nukleinsäure, kristalline form davon sowie durchmusterungsverfahren, bei dem es verwendet wird |
| US20040120964A1 (en) * | 2001-10-29 | 2004-06-24 | Mikszta John A. | Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses |
| EP1572933A4 (de) * | 2002-02-13 | 2007-09-05 | Univ Duke | Modulation der immunantwort durch polypeptide als antwort auf nichtpeptidischen bindungsstress |
| ES2433915T3 (es) * | 2002-05-21 | 2013-12-13 | Irun R. Cohen | Vacunas de ADN que codifican proteínas de choque térmico |
| EP1539241A2 (de) * | 2002-08-30 | 2005-06-15 | Becton, Dickinson and Company | Verfahren zur kontrolle der pharmakokinetik von immunomodulatorischen verbindungen |
| WO2004033657A2 (en) * | 2002-10-07 | 2004-04-22 | Antigenics, Inc. | Heat shock protein binding fragments of cd91, and uses thereof |
| EP1578459A3 (de) * | 2002-10-25 | 2005-11-23 | University of Connecticut Health Center | Gerät und verfahren für die immuntherapie von krebs durch kontrollierte zelllyse |
| US9701725B2 (en) * | 2003-05-05 | 2017-07-11 | The Johns Hopkins University | Anti-cancer DNA vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| JP2008500006A (ja) * | 2003-05-21 | 2008-01-10 | バイオテック トゥールス ソシエテ アノニム | ペプチド複合体 |
| BRPI0411428A (pt) * | 2003-06-13 | 2006-07-25 | Becton Dickinson Co | distribuição intradérmica de agentes biologicamente ativos |
| AU2004270113A1 (en) * | 2003-08-26 | 2005-03-17 | Becton, Dickinson And Company | Methods for intradermal delivery of therapeutics agents |
| AU2004291107B2 (en) | 2003-11-14 | 2010-09-30 | Brigham And Women's Hospital, Inc. | Methods of modulating immunity |
| US20050256499A1 (en) * | 2004-03-03 | 2005-11-17 | Pettis Ronald J | Methods and devices for improving delivery of a substance to skin |
| WO2005115360A2 (en) * | 2004-05-11 | 2005-12-08 | Becton, Dickinson And Company | Formulations of anti-pain agents and methods of using the same |
| EP1765402A2 (de) * | 2004-06-04 | 2007-03-28 | Duke University | Verfahren und zusammensetzungen zur verstärkung der immunität mittels in-vivo-abnahme von immunsuppressiver zellaktivität |
| WO2006073970A2 (en) * | 2005-01-06 | 2006-07-13 | The Johns Hopkins University | Rna interference that blocks expression of pro-apoptotic proteins potentiates immunity induced by dna and transfected dendritic cell vaccines |
| EP1846026A4 (de) * | 2005-01-26 | 2008-07-02 | Univ Johns Hopkins | Antikrebs-dna-impfstoff mit plasmiden zur kodierung eines mutierten onkoprotein-antigens und von calreticulin |
| WO2007038083A2 (en) * | 2005-09-21 | 2007-04-05 | New York University | Heat shock proteins from mycobacterium leprae and uses thereof |
| US7377231B2 (en) * | 2005-10-19 | 2008-05-27 | Ming-Liang Tsai | Retractable pet house |
| US20090118173A1 (en) * | 2006-01-24 | 2009-05-07 | Universiteit Utrecht Uu Holding B.V. | Treatment and prevention of inflammatory bowel diseases |
| US20100330105A1 (en) * | 2006-08-22 | 2010-12-30 | John Hopkins University | Anticancer Combination Therapies |
| US9085638B2 (en) | 2007-03-07 | 2015-07-21 | The Johns Hopkins University | DNA vaccine enhancement with MHC class II activators |
| US20080260765A1 (en) * | 2007-03-15 | 2008-10-23 | Johns Hopkins University | HPV DNA Vaccines and Methods of Use Thereof |
| JP2010532785A (ja) * | 2007-07-06 | 2010-10-14 | ウニベルジテイト・ウトレヒト・ホールディング・ビー.ブイ. | 炎症性疾患および自己免疫疾患の治療および予防 |
| US8475785B2 (en) | 2008-03-03 | 2013-07-02 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
| CA2718884C (en) | 2008-03-20 | 2016-11-22 | University Of Miami | Heat shock protein gp96 vaccination and methods of using same |
| US20090285861A1 (en) * | 2008-04-17 | 2009-11-19 | Tzyy-Choou Wu | Tumor cell-based cancer immunotherapeutic compositions and methods |
| PT2484371E (pt) | 2008-06-26 | 2015-03-03 | Orphazyme Aps | Uso da hsp70 como um regulador da atividade enzimática |
| US20110223196A1 (en) * | 2008-11-21 | 2011-09-15 | University Of Miami | Hiv/siv vaccines for the generation of mucosal and systemic immunity |
| WO2010086418A1 (en) * | 2009-01-29 | 2010-08-05 | Alfa Biogene International B.V. | Functional food product comprising heat shock protein or a hydrolysate thereof |
| CA2817773A1 (en) | 2010-11-30 | 2012-06-07 | Orphazyme Aps | Methods for increasing intracellular activity of hsp70 |
| EP2673050B1 (de) * | 2011-02-10 | 2016-03-30 | Alfa Biogene International B.V. | Hsp pflanzlichen ursprungs zur behandlung von nahrungsmittelallergie |
| US20140341935A1 (en) * | 2011-08-30 | 2014-11-20 | Loyola University Chicago | MUTANT HSP70i TO PREVENT AUTOIMMUNE DISEASE |
| ES2881860T3 (es) | 2014-09-15 | 2021-11-30 | Orphazyme As | Formulación de arimoclomol |
| JP6744318B2 (ja) | 2015-02-06 | 2020-08-26 | ヒート バイオロジクス,インコーポレイテッド | ワクチンおよび共刺激分子を共発現するベクター |
| IL293135A (en) | 2015-05-13 | 2022-07-01 | Agenus Inc | Composition comprising at least two different complexes of a purified stress protein bound to an antigenic peptide |
| CN105749251A (zh) * | 2016-04-08 | 2016-07-13 | 中国科学院微生物研究所 | 热休克蛋白gp96在预防和治疗1型糖尿病中的应用 |
| WO2017178029A1 (en) | 2016-04-13 | 2017-10-19 | Orphazyme Aps | Heat shock proteins and cholesterol homeostasis |
| RU2021117465A (ru) | 2016-04-29 | 2021-07-22 | Орфазим А/С | Аримокломол для лечения ассоциированных с глюкоцереброзидазой нарушений |
| CN105963681B (zh) * | 2016-05-09 | 2019-09-06 | 佛山热休生物技术有限公司 | 热休克蛋白gp96在治疗系统性红斑狼疮中的应用 |
| CN106039287B (zh) * | 2016-06-28 | 2019-12-31 | 中国科学院微生物研究所 | 热休克蛋白gp96在治疗类风湿性关节炎中的应用 |
| US11666649B2 (en) | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
| US11548930B2 (en) | 2017-04-04 | 2023-01-10 | Heat Biologics, Inc. | Intratumoral vaccination |
| US11065317B2 (en) | 2018-04-26 | 2021-07-20 | Agenus Inc. | Heat shock protein-binding peptide compositions and methods of use thereof |
| KR20230128462A (ko) | 2020-11-19 | 2023-09-05 | 제브라 덴마크 에이/에스 | 아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정 |
| JP2024538064A (ja) | 2021-10-14 | 2024-10-18 | ティジアーナ ライフ サイエンシズ パブリック リミティド カンパニー | ミクログリア活性化を抑制するための方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5268170A (en) * | 1986-09-09 | 1993-12-07 | Yeda Research And Development Co., Ltd. | Methods of treatment and diagnosis of autoimmune diseases, especially arthritic conditions |
| NL8703107A (nl) * | 1987-12-22 | 1989-07-17 | Nederlanden Staat | Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten. |
| ATE127345T1 (de) * | 1988-06-15 | 1995-09-15 | Whitehead Biomedical Inst | Stressproteine und verwendungen dafür. |
| WO1994029459A1 (en) * | 1993-06-04 | 1994-12-22 | Whitehead Institute For Biomedical Research | Stress proteins and uses therefor |
| US5578303A (en) * | 1989-03-14 | 1996-11-26 | Yeda Research And Development Co. Ltd. | Diagnosis and treatment of insulin dependent diabetes mellitus |
| NZ276672A (en) * | 1993-11-30 | 1998-01-26 | Univ Queensland | Antagonists (abs) to chaperonin 10 (cpn 10) protein |
| US5750119A (en) * | 1994-01-13 | 1998-05-12 | Mount Sinai School Of Medicine Of The City University Of New York | Immunotherapeutic stress protein-peptide complexes against cancer |
| DE69505376T2 (de) * | 1994-06-09 | 1999-04-08 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno, Den Haag/S'gravenhage | Alpha b crystallin zur verwendung in diagnose und therapie von autoimmunkrankheiten, besonders multipler skerose |
| US5837251A (en) * | 1995-09-13 | 1998-11-17 | Fordham University | Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases |
| WO1997024140A1 (en) * | 1996-01-02 | 1997-07-10 | The Board Of Trustees Of Leland Stanford Junior University | Interaction of hla proteins with members of the hsp70 family of proteins |
| EP0937258A2 (de) * | 1996-10-29 | 1999-08-25 | Fred Hutchinson Cancer Research Center, Inc. | Humane durch zellstress regulierte mhc class i gene |
| WO1998023735A1 (en) * | 1996-11-26 | 1998-06-04 | Stressgen Biotechnologies Corp. | Immune responses using compositions containing stress proteins |
| US5830464A (en) * | 1997-02-07 | 1998-11-03 | Fordham University | Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy |
-
1997
- 1997-10-16 US US08/951,789 patent/US6007821A/en not_active Expired - Lifetime
-
1998
- 1998-10-14 EP EP98953509A patent/EP1024701A4/de not_active Withdrawn
- 1998-10-14 JP JP2000515445A patent/JP2002514570A/ja active Pending
- 1998-10-14 WO PCT/US1998/021706 patent/WO1999018801A1/en not_active Ceased
- 1998-10-14 AU AU10862/99A patent/AU756472B2/en not_active Ceased
- 1998-10-14 CA CA002306062A patent/CA2306062A1/en not_active Abandoned
- 1998-10-16 ZA ZA989461A patent/ZA989461B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002514570A (ja) | 2002-05-21 |
| WO1999018801A9 (en) | 1999-07-01 |
| US6007821A (en) | 1999-12-28 |
| AU756472B2 (en) | 2003-01-16 |
| EP1024701A1 (de) | 2000-08-09 |
| CA2306062A1 (en) | 1999-04-22 |
| AU1086299A (en) | 1999-05-03 |
| EP1024701A4 (de) | 2000-12-06 |
| WO1999018801A1 (en) | 1999-04-22 |
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