ZA988952B - New osteoblast-specific mitogens, methods of preparing same and drugs containing such compounds. - Google Patents

New osteoblast-specific mitogens, methods of preparing same and drugs containing such compounds.

Info

Publication number
ZA988952B
ZA988952B ZA9808952A ZA988952A ZA988952B ZA 988952 B ZA988952 B ZA 988952B ZA 9808952 A ZA9808952 A ZA 9808952A ZA 988952 A ZA988952 A ZA 988952A ZA 988952 B ZA988952 B ZA 988952B
Authority
ZA
South Africa
Prior art keywords
compounds
methods
preparing same
drugs containing
specific mitogens
Prior art date
Application number
ZA9808952A
Other languages
English (en)
Inventor
Angelika Esswein
Lothar Kling
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of ZA988952B publication Critical patent/ZA988952B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9808952A 1997-10-02 1998-10-01 New osteoblast-specific mitogens, methods of preparing same and drugs containing such compounds. ZA988952B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97117124A EP0906759A1 (de) 1997-10-02 1997-10-02 Neue Osteoblastenspezifische Mitogene: Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ZA988952B true ZA988952B (en) 2000-04-03

Family

ID=8227430

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9808952A ZA988952B (en) 1997-10-02 1998-10-01 New osteoblast-specific mitogens, methods of preparing same and drugs containing such compounds.

Country Status (16)

Country Link
US (1) US6197759B1 (zh)
EP (2) EP0906759A1 (zh)
JP (2) JP2001518511A (zh)
KR (1) KR100392207B1 (zh)
CN (1) CN1191070C (zh)
AR (1) AR013538A1 (zh)
AT (1) ATE232103T1 (zh)
AU (1) AU738479B2 (zh)
BR (1) BR9813020A (zh)
CA (1) CA2304821C (zh)
DE (1) DE69811253T2 (zh)
DK (1) DK1019062T3 (zh)
ES (1) ES2191350T3 (zh)
TR (1) TR200000875T2 (zh)
WO (1) WO1999017781A1 (zh)
ZA (1) ZA988952B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2003041717A1 (ja) * 2001-11-12 2005-03-03 小野薬品工業株式会社 プロスタグランジン誘導体を有効成分とする局所投与用持続性フィルム状製剤
WO2004000232A2 (en) 2002-06-24 2003-12-31 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Complexed-acidic-phospholipid-collagen composites for bone induction
KR100789323B1 (ko) * 2005-07-20 2007-12-28 주식회사 엔지켐 글리세롤 유도체의 위치 선택적 제조방법 및 그 중간체
US20100266691A1 (en) * 2009-04-15 2010-10-21 Battelle Memorial Institute Agents and Methods to Stimulate Bone Healing
CN113842504B (zh) * 2021-09-22 2022-12-09 苏州大学附属第二医院 一种用于骨再生的多功能电纺支架的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4164560A (en) 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
PL151315B1 (pl) * 1987-04-17 1990-08-31 Sposób wytwarzania nowych związków powierzchniowo czynnych
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US5238965A (en) * 1991-05-31 1993-08-24 The Procter & Gamble Company Methods of using lysophosphatidic acids for regulating skin wrinkles
MX9203083A (es) 1991-06-21 1994-08-31 Genetics Inst Formulaciones farmaceuticas de proteinas osteogenicas.
US5300687A (en) * 1991-07-18 1994-04-05 Ortho Pharmaceutical Corporation Trifluoromethylbenzylphosphonates useful in treating osteoporosis
WO1993020859A1 (en) 1992-04-20 1993-10-28 Board Of Regents Of The University Of Washington Sustained release compositions for delivery of growth factors
CA2093836A1 (en) 1992-04-24 1993-10-25 Wayne Gombotz Biodegradable tgf-.beta. delivery system for bone regeneration
US5565439A (en) * 1992-11-24 1996-10-15 The Procter & Gamble Company Methods of using lysophosphatidic acid for treating hyperproliferative conditions
NO940913L (no) 1993-03-26 1994-09-27 Bristol Myers Squibb Co Preparater for kontrollert frigivelse av biologisk aktiv TGF-
DE69412538T2 (de) * 1993-05-18 1998-12-24 Takeda Chemical Industries, Ltd., Osaka Benzopyran-Derivate und ihre Verwendung
ES2065855B1 (es) * 1993-05-31 1995-09-01 Menarini Lab Procedimiento para la preparacion de nuevos derivados desoxiazafosfolipidicos con accion inhibidora de la fosfolipasa a2, nuevos derivados desoxiazafosfolipidicos obtenidos y utilizacion de los mismos.
DE19544635A1 (de) 1995-11-30 1997-06-05 Boehringer Mannheim Gmbh Neue Aminoalkoholderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
ES2191350T3 (es) 2003-09-01
ATE232103T1 (de) 2003-02-15
EP1019062A1 (en) 2000-07-19
JP2004217667A (ja) 2004-08-05
KR100392207B1 (ko) 2003-07-23
CN1271289A (zh) 2000-10-25
DK1019062T3 (da) 2003-05-26
EP1019062B1 (en) 2003-02-05
DE69811253D1 (de) 2003-03-13
CA2304821A1 (en) 1999-04-15
CN1191070C (zh) 2005-03-02
AR013538A1 (es) 2000-12-27
EP0906759A1 (de) 1999-04-07
JP2001518511A (ja) 2001-10-16
US6197759B1 (en) 2001-03-06
CA2304821C (en) 2005-08-02
AU1148399A (en) 1999-04-27
DE69811253T2 (de) 2003-12-04
BR9813020A (pt) 2000-08-15
KR20010030822A (ko) 2001-04-16
WO1999017781A1 (en) 1999-04-15
AU738479B2 (en) 2001-09-20
TR200000875T2 (tr) 2000-11-21

Similar Documents

Publication Publication Date Title
PL318277A1 (en) Novel substituted axazolydinones, method of obtaining and drugs containing them
SG87776A1 (en) Substituted isoquinoline-3-carboxamides, their preparation and their use as pharmaceuticals
PL317929A1 (en) Pyrido-condenset thenyl- and furanyl oxazolydinones, method of obtaining and drugs containing them
ZA9811759B (en) Novel indole derivatives, processes for their preparation, their use and pharmaceutical compositions containing them.
HK1028769A1 (en) 2-aryl-8-oxodihydropurine derivatives, process for producing the same, medicinal compositions containing the same, and intermediates thereof
HK1078561A1 (en) Novel compounds, their use and preparation
HUP0001508A3 (en) 4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them
PL338143A1 (en) Derivatives acylpiperazinylpyrimidines, method of obtaining and drugs containing them
ZA985456B (en) Solid pharmaceutical composition containing benzofuran derivatives.
HUP0002718A3 (en) Piperazine derivatives, process for their preparation and medicaments containing the same
HUP0004226A3 (en) Novel vitamin d analogues, pharmaceutical compositions containing thereof and process for preparing the same
IL134691A0 (en) Compounds containing six-membered rings, processes for their preparation, and their use as medicaments
HK1015789A1 (en) Propanolamine derivatives, processes for their preparation, pharmaceuticals comprising these compounds, and their use.
ZA9811506B (en) Novel pharmaceutical.
HUP0004561A3 (en) Dihydrobenzofurans, pharmaceutical compositions containing them and use thereof
HRP980258B1 (en) New triazole derivatives, process for the preparation thereof and pharmaceutical preparations containing them
ZA988711B (en) New tetracycles, process for their production and pharmaceutical preparations containing these compounds.
ZA979059B (en) 10, 13, 15-Trioxatricyclo [9.2.1.1.<9.6>]-pentadecanone derivatives, method for the production thereof and medicaments containing these compounds.
HUP0001551A3 (en) Improved method for producing thiazolidinediones, thiazolidinediones and pharmaceutical compositions containing the same
HUP9902311A3 (en) New triazolopurines, method of preparing them and their use as drugs
AU3473695A (en) Novel 4-aminopyridazines, method of preparing them and drugs containing these compounds
CY2392B1 (en) Method for the preparation of alpha-bromolactam derivatives.
ZA988952B (en) New osteoblast-specific mitogens, methods of preparing same and drugs containing such compounds.
PL324588A1 (en) Novel compounds-substituted piperydinodiones-2,6, method of obtaining them and drug containing such compounds
CY2293B1 (en) Slow-release pharmaceutical formulations containing mizolastin