ZA98868B - Novel compounds. - Google Patents

Novel compounds.

Info

Publication number
ZA98868B
ZA98868B ZA9800868A ZA98868A ZA98868B ZA 98868 B ZA98868 B ZA 98868B ZA 9800868 A ZA9800868 A ZA 9800868A ZA 98868 A ZA98868 A ZA 98868A ZA 98868 B ZA98868 B ZA 98868B
Authority
ZA
South Africa
Prior art keywords
novel compounds
novel
compounds
Prior art date
Application number
ZA9800868A
Other languages
English (en)
Inventor
Barry Barton
John Patrick Griffin
Roy Henry Mosher
Ashish Sudhakar Paradkar
Cecilia Anders
Susan Jensen
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA98868B publication Critical patent/ZA98868B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9800868A 1997-02-04 1998-02-03 Novel compounds. ZA98868B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9702218.0A GB9702218D0 (en) 1997-02-04 1997-02-04 Novel product

Publications (1)

Publication Number Publication Date
ZA98868B true ZA98868B (en) 1999-08-03

Family

ID=10807030

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9800868A ZA98868B (en) 1997-02-04 1998-02-03 Novel compounds.

Country Status (32)

Country Link
US (5) US6936458B1 (id)
EP (2) EP1405913A3 (id)
JP (2) JP4227199B2 (id)
KR (2) KR20050053794A (id)
CN (2) CN1192107C (id)
AP (1) AP1320A (id)
AR (2) AR011100A1 (id)
AT (1) ATE312926T1 (id)
AU (1) AU735782B2 (id)
BG (1) BG103704A (id)
BR (1) BR9807144A (id)
CA (1) CA2279207A1 (id)
DE (1) DE69832783T2 (id)
DZ (1) DZ2413A1 (id)
EA (1) EA003773B1 (id)
ES (1) ES2255149T3 (id)
GB (1) GB9702218D0 (id)
HU (1) HUP0001048A3 (id)
ID (1) ID22144A (id)
IL (1) IL131043A0 (id)
MA (1) MA24464A1 (id)
MY (1) MY140928A (id)
NO (1) NO993758D0 (id)
NZ (1) NZ336894A (id)
OA (1) OA11082A (id)
PL (1) PL334961A1 (id)
SK (1) SK105499A3 (id)
TR (1) TR199901862T2 (id)
TW (2) TW589377B (id)
UY (2) UY24874A1 (id)
WO (1) WO1998033896A2 (id)
ZA (1) ZA98868B (id)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1218486A4 (en) * 1999-09-16 2002-11-04 Univ Johns Hopkins IMPROVEMENT OF CLAVULIC ACID PRODUCTION
EP1228218A2 (en) * 1999-10-22 2002-08-07 Smithkline Beecham Plc 5r clavam producing microorganisms with deleted lat and cvm genes
GB0308696D0 (en) 2003-04-15 2003-05-21 Glaxo Group Ltd New process
EP2589663A1 (en) 2011-11-04 2013-05-08 LEK Pharmaceuticals d.d. Process for production of clavulanic acid
CN107964522B (zh) * 2018-01-04 2020-12-08 上海交通大学 海洋链霉菌dut11及其抗补体活性应用
MX2022000250A (es) 2019-07-05 2022-02-03 Glaxosmithkline Ip No 2 Ltd Streptomyces clavuligerus.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
IE43790B1 (en) * 1975-02-07 1981-06-03 Glaxo Lab Ltd -lactam antibiotic in purified form
GB1585661A (en) 1976-06-08 1981-03-11 Glaxo Lab Ltd Clavam derivatives
JPS589679B2 (ja) 1977-02-24 1983-02-22 武田薬品工業株式会社 抗生物質の製造法
US4202819A (en) 1979-05-04 1980-05-13 Hoffman-La Roche Inc. 2-(3-Alanyl)clavam antibiotic
GB8521516D0 (en) * 1985-08-29 1985-10-02 Beecham Group Plc Compounds
GB9020683D0 (en) 1990-09-22 1990-11-07 Univ Strathclyde Isolation of dna
CA2108113C (en) * 1993-10-08 2006-12-05 Susan E. Jensen Dna sequence encoding enzymes of clavulanic acid biosynthesis

Also Published As

Publication number Publication date
MA24464A1 (fr) 1998-10-01
EA003773B1 (ru) 2003-08-28
EA199900718A1 (ru) 2000-02-28
KR20050053794A (ko) 2005-06-08
EP0970198B1 (en) 2005-12-14
AR011100A1 (es) 2000-08-02
TW589377B (en) 2004-06-01
AP1320A (en) 2004-10-29
BR9807144A (pt) 2000-01-25
KR100514964B1 (ko) 2005-09-15
CN1696301A (zh) 2005-11-16
US6936458B1 (en) 2005-08-30
MY140928A (en) 2010-02-12
ES2255149T3 (es) 2006-06-16
GB9702218D0 (en) 1997-03-26
US20030166175A1 (en) 2003-09-04
UY25197A1 (es) 1998-11-27
NO993758L (no) 1999-08-03
JP4227199B2 (ja) 2009-02-18
AP9901614A0 (en) 1999-09-30
IL131043A0 (en) 2001-01-28
EP1405913A2 (en) 2004-04-07
DZ2413A1 (fr) 2003-01-04
US20030124690A1 (en) 2003-07-03
HUP0001048A2 (hu) 2000-08-28
CN1251612A (zh) 2000-04-26
CN1192107C (zh) 2005-03-09
EP1405913A3 (en) 2004-08-04
TW200307041A (en) 2003-12-01
HUP0001048A3 (en) 2001-09-28
TR199901862T2 (xx) 2000-12-21
NO993758D0 (no) 1999-08-03
OA11082A (en) 2003-03-13
AR018304A2 (es) 2001-11-14
US20070298470A1 (en) 2007-12-27
ATE312926T1 (de) 2005-12-15
US20030022321A1 (en) 2003-01-30
JP2001511001A (ja) 2001-08-07
BG103704A (en) 2000-05-31
DE69832783D1 (de) 2006-01-19
NZ336894A (en) 2001-08-31
JP5042186B2 (ja) 2012-10-03
WO1998033896A3 (en) 1998-11-19
DE69832783T2 (de) 2006-07-20
ID22144A (id) 1999-09-09
CA2279207A1 (en) 1998-08-06
EP0970198A2 (en) 2000-01-12
JP2009022298A (ja) 2009-02-05
PL334961A1 (en) 2000-03-27
US7344869B2 (en) 2008-03-18
UY24874A1 (es) 2001-07-31
WO1998033896A2 (en) 1998-08-06
AU735782B2 (en) 2001-07-12
AU6295398A (en) 1998-08-25
KR20000070723A (ko) 2000-11-25
SK105499A3 (en) 2000-05-16

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