ZA985095B - Rapamycin formulations for oral administration. - Google Patents
Rapamycin formulations for oral administration.Info
- Publication number
- ZA985095B ZA985095B ZA9805095A ZA985095A ZA985095B ZA 985095 B ZA985095 B ZA 985095B ZA 9805095 A ZA9805095 A ZA 9805095A ZA 985095 A ZA985095 A ZA 985095A ZA 985095 B ZA985095 B ZA 985095B
- Authority
- ZA
- South Africa
- Prior art keywords
- oral administration
- rapamycin formulations
- rapamycin
- formulations
- oral
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87496597A | 1997-06-13 | 1997-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA985095B true ZA985095B (en) | 1999-12-13 |
Family
ID=25364977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9805095A ZA985095B (en) | 1997-06-13 | 1998-06-11 | Rapamycin formulations for oral administration. |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0994697B1 (es) |
| JP (1) | JP2002504124A (es) |
| KR (1) | KR20010013650A (es) |
| CN (1) | CN1133424C (es) |
| AR (1) | AR012971A1 (es) |
| AT (1) | ATE283687T1 (es) |
| AU (1) | AU743584B2 (es) |
| BR (1) | BR9810746A (es) |
| CA (1) | CA2293793C (es) |
| CZ (1) | CZ295276B6 (es) |
| DE (1) | DE69827947T2 (es) |
| DK (1) | DK0994697T3 (es) |
| ES (1) | ES2232948T3 (es) |
| HU (1) | HUP0003341A3 (es) |
| IL (1) | IL132986A0 (es) |
| NO (1) | NO996044L (es) |
| NZ (1) | NZ501652A (es) |
| PL (1) | PL337320A1 (es) |
| PT (1) | PT994697E (es) |
| RU (1) | RU2184541C2 (es) |
| SK (1) | SK284472B6 (es) |
| TR (1) | TR199903065T2 (es) |
| TW (1) | TW574040B (es) |
| UA (1) | UA65573C2 (es) |
| WO (1) | WO1998056358A1 (es) |
| ZA (1) | ZA985095B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH686761A5 (de) | 1993-05-27 | 1996-06-28 | Sandoz Ag | Galenische Formulierungen. |
| EP1709974A3 (en) * | 2000-06-16 | 2006-12-06 | Wyeth | Method of treating cardiovascular disease using rapamycin |
| US20020013335A1 (en) * | 2000-06-16 | 2002-01-31 | American Home Products Corporation | Method of treating cardiovascular disease |
| US6670355B2 (en) | 2000-06-16 | 2003-12-30 | Wyeth | Method of treating cardiovascular disease |
| JP4969747B2 (ja) * | 2001-01-19 | 2012-07-04 | 武田薬品工業株式会社 | 錠剤フィルムコーティング用組成物 |
| GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
| KR101004224B1 (ko) | 2002-02-01 | 2010-12-27 | 어리어드 파마슈티칼스, 인코포레이티드 | 인 함유 화합물 및 이의 용도 |
| GB0602632D0 (en) * | 2006-02-08 | 2006-03-22 | Pliva Istrazivacki Inst D O O | Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus |
| CN102138903B (zh) * | 2011-03-17 | 2012-12-12 | 苏州特瑞药业有限公司 | 一种依维莫司固体口服药物组合物 |
| CN110585159B (zh) * | 2019-09-12 | 2021-11-02 | 杭州华东医药集团新药研究院有限公司 | 一种含有西罗莫司的片剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0525960B1 (en) * | 1991-06-18 | 1996-03-20 | American Home Products Corporation | Use of rapamycin for the treatment of adult T-cell leukemia/lymphoma |
| US5352783A (en) * | 1993-06-09 | 1994-10-04 | Merck & Co., Inc. | Microbial transformation product having immunosuppressive activity |
| IL111004A (en) * | 1993-09-30 | 1998-06-15 | American Home Prod | Oral formulations of rapamycin |
| US5536729A (en) * | 1993-09-30 | 1996-07-16 | American Home Products Corporation | Rapamycin formulations for oral administration |
| US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| CA2230748C (en) * | 1997-03-14 | 2010-08-03 | American Home Products Corporation | Rapamycin formulations for oral administration |
-
1998
- 1998-06-11 AT AT98926557T patent/ATE283687T1/de not_active IP Right Cessation
- 1998-06-11 CZ CZ19994502A patent/CZ295276B6/cs not_active IP Right Cessation
- 1998-06-11 TR TR1999/03065T patent/TR199903065T2/xx unknown
- 1998-06-11 PT PT98926557T patent/PT994697E/pt unknown
- 1998-06-11 ES ES98926557T patent/ES2232948T3/es not_active Expired - Lifetime
- 1998-06-11 SK SK1717-99A patent/SK284472B6/sk unknown
- 1998-06-11 PL PL98337320A patent/PL337320A1/xx unknown
- 1998-06-11 AR ARP980102784A patent/AR012971A1/es unknown
- 1998-06-11 TW TW087109298A patent/TW574040B/zh not_active IP Right Cessation
- 1998-06-11 WO PCT/US1998/012142 patent/WO1998056358A1/en active IP Right Grant
- 1998-06-11 DK DK98926557T patent/DK0994697T3/da active
- 1998-06-11 CN CNB988060965A patent/CN1133424C/zh not_active Expired - Fee Related
- 1998-06-11 JP JP50321399A patent/JP2002504124A/ja not_active Ceased
- 1998-06-11 KR KR1019997011662A patent/KR20010013650A/ko active IP Right Grant
- 1998-06-11 IL IL13298698A patent/IL132986A0/xx unknown
- 1998-06-11 EP EP98926557A patent/EP0994697B1/en not_active Expired - Lifetime
- 1998-06-11 NZ NZ501652A patent/NZ501652A/xx unknown
- 1998-06-11 AU AU78368/98A patent/AU743584B2/en not_active Ceased
- 1998-06-11 HU HU0003341A patent/HUP0003341A3/hu unknown
- 1998-06-11 RU RU2000100944/14A patent/RU2184541C2/ru not_active IP Right Cessation
- 1998-06-11 ZA ZA9805095A patent/ZA985095B/xx unknown
- 1998-06-11 CA CA002293793A patent/CA2293793C/en not_active Expired - Fee Related
- 1998-06-11 DE DE69827947T patent/DE69827947T2/de not_active Expired - Fee Related
- 1998-06-11 BR BR9810746-1A patent/BR9810746A/pt active Search and Examination
- 1998-11-06 UA UA2000010192A patent/UA65573C2/uk unknown
-
1999
- 1999-12-08 NO NO996044A patent/NO996044L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT994697E (pt) | 2005-02-28 |
| DE69827947T2 (de) | 2005-04-21 |
| NZ501652A (en) | 2001-09-28 |
| WO1998056358A1 (en) | 1998-12-17 |
| BR9810746A (pt) | 2000-09-19 |
| NO996044D0 (no) | 1999-12-08 |
| DK0994697T3 (da) | 2005-02-14 |
| EP0994697B1 (en) | 2004-12-01 |
| UA65573C2 (uk) | 2004-04-15 |
| HUP0003341A3 (en) | 2001-03-28 |
| HUP0003341A2 (hu) | 2001-02-28 |
| PL337320A1 (en) | 2000-08-14 |
| CA2293793A1 (en) | 1998-12-17 |
| CZ450299A3 (cs) | 2000-08-16 |
| AU7836898A (en) | 1998-12-30 |
| SK171799A3 (en) | 2000-07-11 |
| JP2002504124A (ja) | 2002-02-05 |
| TW574040B (en) | 2004-02-01 |
| IL132986A0 (en) | 2001-03-19 |
| EP0994697A1 (en) | 2000-04-26 |
| CZ295276B6 (cs) | 2005-06-15 |
| CN1133424C (zh) | 2004-01-07 |
| SK284472B6 (sk) | 2005-04-01 |
| TR199903065T2 (xx) | 2000-09-21 |
| KR20010013650A (ko) | 2001-02-26 |
| AU743584B2 (en) | 2002-01-31 |
| NO996044L (no) | 1999-12-08 |
| AR012971A1 (es) | 2000-11-22 |
| DE69827947D1 (de) | 2005-01-05 |
| RU2184541C2 (ru) | 2002-07-10 |
| ES2232948T3 (es) | 2005-06-01 |
| ATE283687T1 (de) | 2004-12-15 |
| CN1259864A (zh) | 2000-07-12 |
| CA2293793C (en) | 2006-07-11 |
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