ZA975898B - Diamide derivatives of anthranilic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use. - Google Patents

Diamide derivatives of anthranilic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use.

Info

Publication number
ZA975898B
ZA975898B ZA9705898A ZA975898A ZA975898B ZA 975898 B ZA975898 B ZA 975898B ZA 9705898 A ZA9705898 A ZA 9705898A ZA 975898 A ZA975898 A ZA 975898A ZA 975898 B ZA975898 B ZA 975898B
Authority
ZA
South Africa
Prior art keywords
pct
anthranilic acid
preparation
pharmaceutical use
diamide derivatives
Prior art date
Application number
ZA9705898A
Other languages
English (en)
Inventor
Francesco Makovec
Walter Peris
Lucio Claudio Rovati
Luigi Angelo Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of ZA975898B publication Critical patent/ZA975898B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
ZA9705898A 1996-07-02 1997-07-02 Diamide derivatives of anthranilic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use. ZA975898B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96TO000564A IT1286141B1 (it) 1996-07-02 1996-07-02 Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.

Publications (1)

Publication Number Publication Date
ZA975898B true ZA975898B (en) 1998-01-30

Family

ID=11414751

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9705898A ZA975898B (en) 1996-07-02 1997-07-02 Diamide derivatives of anthranilic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use.

Country Status (13)

Country Link
US (1) US6075033A (da)
EP (1) EP0918754B1 (da)
JP (1) JP2000515497A (da)
AT (1) ATE380178T1 (da)
AU (1) AU724814B2 (da)
CA (1) CA2259345C (da)
DE (1) DE69738349T2 (da)
DK (1) DK0918754T3 (da)
ES (1) ES2299184T3 (da)
IT (1) IT1286141B1 (da)
PT (1) PT918754E (da)
WO (1) WO1998000404A1 (da)
ZA (1) ZA975898B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935219A1 (de) 1999-07-27 2001-02-01 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
CA2445477A1 (en) * 2001-05-11 2002-11-21 Yamanouchi Pharmaceutical Co., Ltd. Antitumor agents
JP5197361B2 (ja) * 2005-06-06 2013-05-15 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ 睡眠障害を処置するための組成物および方法
EP2275421A1 (en) 2009-07-15 2011-01-19 Rottapharm S.p.A. Spiro amino compounds suitable for the treatment of inter alia sleep disorders and drug addiction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241029B (it) * 1990-12-11 1993-12-27 Rotta Research Lab Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione
IT1263116B (it) * 1992-04-09 1996-07-30 Rotta Research Lab Derivati basici dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso farmaceutico
IT1264765B1 (it) * 1993-03-10 1996-10-04 Rotta Research Lab Derivati dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso come farmaci potenzianti la
IT1261255B (it) * 1993-09-09 1996-05-09 Rotta Research Lab Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico.
IT1276462B1 (it) * 1995-07-03 1997-10-31 Rotta Research Lab Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico

Also Published As

Publication number Publication date
ATE380178T1 (de) 2007-12-15
ES2299184T3 (es) 2008-05-16
EP0918754A1 (en) 1999-06-02
EP0918754B1 (en) 2007-12-05
JP2000515497A (ja) 2000-11-21
AU724814B2 (en) 2000-09-28
AU3344897A (en) 1998-01-21
ITTO960564A1 (it) 1998-01-02
PT918754E (pt) 2008-03-04
DE69738349T2 (de) 2008-11-13
US6075033A (en) 2000-06-13
IT1286141B1 (it) 1998-07-07
ITTO960564A0 (da) 1996-07-02
DK0918754T3 (da) 2008-03-31
DE69738349D1 (de) 2008-01-17
CA2259345C (en) 2006-01-31
CA2259345A1 (en) 1998-01-08
WO1998000404A1 (en) 1998-01-08

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