ZA974984B - New substituted thiazolidine-2,4-dione derivatives, processes for the obtaining thereof, and pharmaceutical compositions containing them. - Google Patents

New substituted thiazolidine-2,4-dione derivatives, processes for the obtaining thereof, and pharmaceutical compositions containing them.

Info

Publication number
ZA974984B
ZA974984B ZA9704984A ZA974984A ZA974984B ZA 974984 B ZA974984 B ZA 974984B ZA 9704984 A ZA9704984 A ZA 9704984A ZA 974984 A ZA974984 A ZA 974984A ZA 974984 B ZA974984 B ZA 974984B
Authority
ZA
South Africa
Prior art keywords
obtaining
processes
pharmaceutical compositions
compositions containing
dione derivatives
Prior art date
Application number
ZA9704984A
Other languages
English (en)
Inventor
Gerard Moinet
Etienne Prugnard
Micheline Kergoat
Gerard Botton
Liliane Doare
Didier Mesangeau
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA974984B publication Critical patent/ZA974984B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9704984A 1996-06-07 1997-06-05 New substituted thiazolidine-2,4-dione derivatives, processes for the obtaining thereof, and pharmaceutical compositions containing them. ZA974984B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9607070A FR2749583B1 (fr) 1996-06-07 1996-06-07 Nouveaux derives de thiazolidine -2,4- dione substitues, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant

Publications (1)

Publication Number Publication Date
ZA974984B true ZA974984B (en) 1997-12-30

Family

ID=9492815

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9704984A ZA974984B (en) 1996-06-07 1997-06-05 New substituted thiazolidine-2,4-dione derivatives, processes for the obtaining thereof, and pharmaceutical compositions containing them.

Country Status (31)

Country Link
US (2) US6437143B2 (cs)
EP (1) EP0918759B1 (cs)
JP (2) JP3067809B2 (cs)
KR (1) KR20000016412A (cs)
CN (2) CN1075811C (cs)
AR (1) AR008387A1 (cs)
AT (1) ATE222897T1 (cs)
AU (1) AU726549B2 (cs)
BR (1) BR9709654A (cs)
CA (1) CA2257275A1 (cs)
CZ (1) CZ397598A3 (cs)
DE (1) DE69715009T2 (cs)
DK (1) DK0918759T3 (cs)
EE (1) EE04015B1 (cs)
ES (1) ES2180995T3 (cs)
FR (1) FR2749583B1 (cs)
HK (1) HK1019601A1 (cs)
HU (1) HUP0001744A3 (cs)
ID (1) ID17810A (cs)
IL (1) IL127408A (cs)
NO (1) NO312100B1 (cs)
NZ (1) NZ333645A (cs)
PL (1) PL330363A1 (cs)
PT (1) PT918759E (cs)
RU (1) RU2169144C2 (cs)
SK (1) SK164598A3 (cs)
TR (1) TR199802518T2 (cs)
TW (1) TW400330B (cs)
UA (1) UA57024C2 (cs)
WO (1) WO1997047612A1 (cs)
ZA (1) ZA974984B (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
CA2344913A1 (en) * 1998-09-21 2000-03-30 University Of Florida Research Foundation, Inc. Antimalarial agents
CN1350526A (zh) * 1999-03-18 2002-05-22 小野药品工业株式会社 噻唑烷衍生物的制备方法
DK1206457T3 (da) 1999-08-27 2004-02-16 Lilly Co Eli Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER
FR2812547B1 (fr) * 2000-08-04 2002-10-31 Lipha Composition pharmaceutique comprenant une association metformine et derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete
FR2822069B1 (fr) * 2001-03-19 2003-06-20 Lipha Composition pharmaceutique comprenant un compose stimulant la secretion d'insuline et un derive de thiazolidinedione et son utilisation pour la preparation de medicamments destines a traiter le diabete
FR2826278B1 (fr) * 2001-06-20 2005-03-25 Lipha Utilisation d'agents antidiabetiques pour fabriquer un medicament ayant un effet cicatrisant
CN100516020C (zh) * 2001-09-26 2009-07-22 艾米斯菲尔技术有限公司 通过二羧化物中间体制备苯氧基链烷酸、链烯酸和炔酸及其盐的方法
FR2838968A1 (fr) * 2002-04-30 2003-10-31 Lipha Association d'insuline et d'un derive de thiazolidinedione et son utilisation pour traiter le diabete
FR2845003A1 (fr) * 2002-09-30 2004-04-02 Merck Sante Sas Utilisation de derives de thiazolidinedione comme inhibiteurs de l'aldose reductase
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
US20060263453A1 (en) * 2004-11-01 2006-11-23 Thomas Smith Methods and compositions for modulating glutamate dehydrogenase
DK3190106T3 (da) 2005-04-04 2019-07-15 Univ Florida Desferrithiocinpolyether-analoger
NZ579994A (en) * 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
ES2830073T3 (es) * 2007-04-11 2021-06-02 Omeros Corp Composiciones y métodos para la profilaxis y el tratamiento de adicciones
US11241420B2 (en) 2007-04-11 2022-02-08 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
US20160331729A9 (en) * 2007-04-11 2016-11-17 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
DE102007028925A1 (de) * 2007-06-22 2008-12-24 Saltigo Gmbh Verfahren zur Herstellung von 2-Phenoxyacetalen und den daraus korrespondierenden 2-Phenoxycarbaldehyden
BR112014014544A2 (pt) 2011-12-16 2017-06-13 Univ Florida usos de análogos de 4'-desferritiocina
US9815777B2 (en) 2013-09-22 2017-11-14 Jiva Pharma, Inc. Metformin salts to treat Type2 diabetes
CA2930966A1 (en) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
CN107708693A (zh) 2015-04-27 2018-02-16 佛罗里达大学研究基金会 代谢程序化的金属螯合剂及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
TW268952B (cs) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
US5614544A (en) * 1993-09-14 1997-03-25 Takeda Chemical Industries, Ltd. Oxazolidinedione derivatives and their use
EP0783496B9 (en) * 1994-08-10 2003-09-03 Takeda Chemical Industries, Ltd. Thiazolidinedione derivatives, their production and use

Also Published As

Publication number Publication date
US20010007875A1 (en) 2001-07-12
IL127408A (en) 2002-08-14
EP0918759B1 (fr) 2002-08-28
DE69715009D1 (de) 2002-10-02
HK1019601A1 (en) 2000-02-18
CA2257275A1 (en) 1997-12-18
ID17810A (id) 1998-01-29
CN1221410A (zh) 1999-06-30
JP3067809B2 (ja) 2000-07-24
AU3031797A (en) 1998-01-07
IL127408A0 (en) 1999-10-28
BR9709654A (pt) 1999-08-10
UA57024C2 (uk) 2003-06-16
NO312100B1 (no) 2002-03-18
EE9800426A (et) 1999-06-15
PL330363A1 (en) 1999-05-10
JP2000226379A (ja) 2000-08-15
AR008387A1 (es) 2000-01-19
JP2000507270A (ja) 2000-06-13
ATE222897T1 (de) 2002-09-15
AU726549B2 (en) 2000-11-09
HUP0001744A3 (en) 2002-09-30
CN1075811C (zh) 2001-12-05
US20030100587A1 (en) 2003-05-29
NO985671L (no) 1998-12-04
KR20000016412A (ko) 2000-03-25
NZ333645A (en) 2000-05-26
NO985671D0 (no) 1998-12-04
TW400330B (en) 2000-08-01
FR2749583B1 (fr) 1998-08-21
RU2169144C2 (ru) 2001-06-20
EE04015B1 (et) 2003-04-15
US6437143B2 (en) 2002-08-20
TR199802518T2 (xx) 1999-04-21
CN1341588A (zh) 2002-03-27
HUP0001744A1 (hu) 2000-11-28
CZ397598A3 (cs) 1999-03-17
PT918759E (pt) 2003-01-31
DE69715009T2 (de) 2003-05-08
ES2180995T3 (es) 2003-02-16
FR2749583A1 (fr) 1997-12-12
WO1997047612A1 (fr) 1997-12-18
SK164598A3 (en) 1999-06-11
DK0918759T3 (da) 2002-11-25
EP0918759A1 (fr) 1999-06-02

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