ZA9710862B - A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives. - Google Patents

A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives.

Info

Publication number
ZA9710862B
ZA9710862B ZA9710862A ZA9710862A ZA9710862B ZA 9710862 B ZA9710862 B ZA 9710862B ZA 9710862 A ZA9710862 A ZA 9710862A ZA 9710862 A ZA9710862 A ZA 9710862A ZA 9710862 B ZA9710862 B ZA 9710862B
Authority
ZA
South Africa
Prior art keywords
triiodo
amino
preparation
acid derivatives
benzenedicarboxylic acid
Prior art date
Application number
ZA9710862A
Other languages
English (en)
Inventor
Nicola Desantis
Original Assignee
Dibra Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dibra Spa filed Critical Dibra Spa
Publication of ZA9710862B publication Critical patent/ZA9710862B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9710862A 1996-12-04 1997-12-03 A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives. ZA9710862B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI002545A IT1286522B1 (it) 1996-12-04 1996-12-04 Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico

Publications (1)

Publication Number Publication Date
ZA9710862B true ZA9710862B (en) 1998-06-23

Family

ID=11375347

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710862A ZA9710862B (en) 1996-12-04 1997-12-03 A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives.

Country Status (12)

Country Link
EP (1) EP0901460B1 (enEXAMPLES)
JP (1) JP4219409B2 (enEXAMPLES)
AU (1) AU5657798A (enEXAMPLES)
CA (1) CA2244884A1 (enEXAMPLES)
DE (2) DE69715616T2 (enEXAMPLES)
ES (1) ES2129384T3 (enEXAMPLES)
IN (1) IN185038B (enEXAMPLES)
IT (1) IT1286522B1 (enEXAMPLES)
NO (1) NO322067B1 (enEXAMPLES)
PT (1) PT901460E (enEXAMPLES)
WO (1) WO1998024757A1 (enEXAMPLES)
ZA (1) ZA9710862B (enEXAMPLES)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803485B2 (en) * 1999-02-26 2004-10-12 Bracco Imaging S.P.A. Process for the preparation of iopamidol
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
KR101098553B1 (ko) * 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법
US8624061B2 (en) * 2008-11-18 2014-01-07 Bracco Imaging S.P.A. Process for the preparation of iodinated contrast agent
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
KR102044772B1 (ko) 2012-12-11 2019-11-14 브라코 이미징 에스.피.에이. (s)-2-아세틸옥시프로피온산 클로라이드의 제조를 위한 연속식 공정
KR101520187B1 (ko) * 2013-10-25 2015-05-13 주식회사 대웅제약 이오프로마이드의 중간체의 제조방법
BR112016010223B1 (pt) 2013-11-05 2021-05-25 Bracco Imaging Spa processo para a preparação de iopamidol, composto para preparação de iopamidol e uso relacionado
CN106458830B (zh) 2014-06-10 2019-03-05 伯拉考成像股份公司 制备(s)-2-乙酰氧基丙酸及其衍生物的方法
PT108524B (pt) * 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
US10836710B2 (en) 2016-12-05 2020-11-17 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
CN116354842B (zh) * 2021-12-20 2024-12-03 重庆圣华曦药业股份有限公司 一种改进的碘美普尔制备方法及其在制剂中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (enEXAMPLES) * 1974-12-13 1978-12-29 Savac Ag
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
CA2130829A1 (en) * 1992-02-28 1993-09-02 William Z. Mccarthy Synthesis of ioversol using a minimal excess of acetoxyacetylchloride

Also Published As

Publication number Publication date
DE901460T1 (de) 1999-08-19
JP4219409B2 (ja) 2009-02-04
AU5657798A (en) 1998-06-29
EP0901460A1 (en) 1999-03-17
ES2129384T3 (es) 2003-04-01
CA2244884A1 (en) 1998-06-11
ITMI962545A0 (it) 1996-12-04
DE69715616T2 (de) 2003-08-07
ITMI962545A1 (it) 1998-06-04
ES2129384T1 (es) 1999-06-16
PT901460E (pt) 2003-01-31
NO983563L (no) 1998-10-02
EP0901460B1 (en) 2002-09-18
DE69715616D1 (de) 2002-10-24
IN185038B (enEXAMPLES) 2000-10-21
JP2000505114A (ja) 2000-04-25
NO322067B1 (no) 2006-08-07
NO983563D0 (no) 1998-08-03
IT1286522B1 (it) 1998-07-15
WO1998024757A1 (en) 1998-06-11

Similar Documents

Publication Publication Date Title
HU9602339D0 (en) Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof
EP0629608A3 (en) N-acyl-N, N ', N'-ethylenediamine triacetic acid derivatives and process for their preparation.
HU9601652D0 (en) Naphthalene derivatives, process for the preparation thereof, and intermediates thereof
HU9502684D0 (en) 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkane-carboxylic acid derivatives
PL344219A1 (en) Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same
ZA9710862B (en) A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives.
HUP9700189A3 (en) Process for producing 5-amino-2,4,6-triiode-1,3-benzenedicarboxylic acid
HUP0100640A3 (en) Process for the preparation of 1,4-dihydropyridines
ZA979059B (en) 10, 13, 15-Trioxatricyclo [9.2.1.1.<9.6>]-pentadecanone derivatives, method for the production thereof and medicaments containing these compounds.
HUP0104507A3 (en) A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl)methylamino]-2,4,6-trijodo-1,3-benzenedicarboxamide
EP0692476A3 (de) Verbessertes Verfahren zur Herstellung von N,N'-Carbonyldiazolen, insbesondere N,N'-Carbonyldiimidazol
IL139023A0 (en) Process for the preparation of 2,3,5-trimethyl-p- benzoquinone
HUP0103373A3 (en) Method for the production of n,n'-carbonyl diazoles
HUP9700923A3 (en) Process for producing 3-amino substituted crotonates
KR19987002519A (en) Process for subsequent codensation of polycondensates , in particular of poyamide 6.6
EP0690053A3 (de) Verfahren zur Herstellung von 2,5-Dihydrofuran
HRP930131A2 (en) Amino-ascorbic acid derivatives, process for the preparation and use thereof
ZA971022B (en) N-(3,3-dimethylbutyl)-l-aspartyl-d-alpha-aminoalkanyoic acid n-(s)- 1-phenyl-1-alkanamide useful as a sweeting agent.
PH31401A (en) Process for the manufacture of form 1 ranitidine hydrochloride.
IL119868A0 (en) Process for the preparation of 4,4'-oxybisphthalic dianhydride
TJ257B (en) Improved process for r/+/-1,2,3,6- tetrahydro-4-phenyl-1-¬(3-phenyl-3- cyclohexen-1-yl)-methyl¾-pyridine or pharmaceutically acceptable salts thereof intermediate substance and process for the preparation thereof
ZA991215B (en) Process for the preparation of 1,3-disubstituted 2-nitroguanidines.
ZA985008B (en) Process for preparing 3,3-dimethylbutyric acid
IL118731A (en) Process for the preparation of 2,2-dialkyl-arylidenecycloalkanones
HUP9800850A3 (en) Triiodinated isophtalic acid diamide derivatives, contrasting agent containing them and process for preparing the said compounds