DE69715616T2 - Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivate - Google Patents
Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivateInfo
- Publication number
- DE69715616T2 DE69715616T2 DE69715616T DE69715616T DE69715616T2 DE 69715616 T2 DE69715616 T2 DE 69715616T2 DE 69715616 T DE69715616 T DE 69715616T DE 69715616 T DE69715616 T DE 69715616T DE 69715616 T2 DE69715616 T2 DE 69715616T2
- Authority
- DE
- Germany
- Prior art keywords
- benzoldicarbonic
- triiod
- amino
- producing
- acid derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI002545A IT1286522B1 (it) | 1996-12-04 | 1996-12-04 | Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico |
| PCT/EP1997/006720 WO1998024757A1 (en) | 1996-12-04 | 1997-12-01 | A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69715616D1 DE69715616D1 (de) | 2002-10-24 |
| DE69715616T2 true DE69715616T2 (de) | 2003-08-07 |
Family
ID=11375347
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69715616T Expired - Lifetime DE69715616T2 (de) | 1996-12-04 | 1997-12-01 | Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivate |
| DE0901460T Pending DE901460T1 (de) | 1996-12-04 | 1997-12-01 | Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivate |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE0901460T Pending DE901460T1 (de) | 1996-12-04 | 1997-12-01 | Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivate |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0901460B1 (de) |
| JP (1) | JP4219409B2 (de) |
| AU (1) | AU5657798A (de) |
| CA (1) | CA2244884A1 (de) |
| DE (2) | DE69715616T2 (de) |
| ES (1) | ES2129384T3 (de) |
| IN (1) | IN185038B (de) |
| IT (1) | IT1286522B1 (de) |
| NO (1) | NO322067B1 (de) |
| PT (1) | PT901460E (de) |
| WO (1) | WO1998024757A1 (de) |
| ZA (1) | ZA9710862B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6803485B2 (en) * | 1999-02-26 | 2004-10-12 | Bracco Imaging S.P.A. | Process for the preparation of iopamidol |
| CN100344606C (zh) * | 2005-12-28 | 2007-10-24 | 江苏省原子医学研究所 | 一种碘昔兰的制备方法 |
| KR101098553B1 (ko) * | 2008-04-30 | 2011-12-26 | 주식회사 엘지생명과학 | 이오프로마이드의 신규한 제조방법 |
| EP2365963B1 (de) * | 2008-11-18 | 2017-06-28 | Bracco Imaging S.p.A | Verfahren zur herstellung eines iodierten kontrastmittels |
| EP2230227A1 (de) | 2009-03-20 | 2010-09-22 | Bracco Imaging S.p.A | Verfahren zur Herstellung von aromatischen Trijodid-Carboxyl- Derivaten |
| EP2243767A1 (de) | 2009-04-21 | 2010-10-27 | Bracco Imaging S.p.A | Verfahren zur Iodierung aromatischer Verbindungen |
| PL2931696T3 (pl) | 2012-12-11 | 2019-01-31 | Bracco Imaging S.P.A | Ciągły sposób otrzymywania kwasu (S)-2-acetyloksypropionowego |
| KR101520187B1 (ko) | 2013-10-25 | 2015-05-13 | 주식회사 대웅제약 | 이오프로마이드의 중간체의 제조방법 |
| ES2674279T3 (es) | 2013-11-05 | 2018-06-28 | Bracco Imaging S.P.A. | Proceso para la preparación de Iopamidol |
| NZ726674A (en) | 2014-06-10 | 2022-12-23 | Bracco Imaging Spa | Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof |
| PT108524B (pt) * | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos |
| WO2018104228A1 (en) | 2016-12-05 | 2018-06-14 | Bracco Imaging Spa | Mechanochemical synthesis of radiographic agents intermediates |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608189A5 (de) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
| WO1993016981A1 (en) * | 1992-02-28 | 1993-09-02 | Mallinckrodt Medical, Inc. | Synthesis of ioversol using a minimal excess of acetoxyacetylchloride |
-
1996
- 1996-12-04 IT IT96MI002545A patent/IT1286522B1/it active IP Right Grant
-
1997
- 1997-12-01 JP JP52518298A patent/JP4219409B2/ja not_active Expired - Fee Related
- 1997-12-01 DE DE69715616T patent/DE69715616T2/de not_active Expired - Lifetime
- 1997-12-01 EP EP97952841A patent/EP0901460B1/de not_active Expired - Lifetime
- 1997-12-01 PT PT97952841T patent/PT901460E/pt unknown
- 1997-12-01 CA CA002244884A patent/CA2244884A1/en not_active Abandoned
- 1997-12-01 DE DE0901460T patent/DE901460T1/de active Pending
- 1997-12-01 ES ES97952841T patent/ES2129384T3/es not_active Expired - Lifetime
- 1997-12-01 AU AU56577/98A patent/AU5657798A/en not_active Abandoned
- 1997-12-01 WO PCT/EP1997/006720 patent/WO1998024757A1/en active IP Right Grant
- 1997-12-03 ZA ZA9710862A patent/ZA9710862B/xx unknown
- 1997-12-03 IN IN2768MA1997 patent/IN185038B/en unknown
-
1998
- 1998-08-03 NO NO19983563A patent/NO322067B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2129384T3 (es) | 2003-04-01 |
| PT901460E (pt) | 2003-01-31 |
| NO322067B1 (no) | 2006-08-07 |
| NO983563D0 (no) | 1998-08-03 |
| AU5657798A (en) | 1998-06-29 |
| IT1286522B1 (it) | 1998-07-15 |
| ES2129384T1 (es) | 1999-06-16 |
| DE69715616D1 (de) | 2002-10-24 |
| EP0901460A1 (de) | 1999-03-17 |
| ITMI962545A1 (it) | 1998-06-04 |
| WO1998024757A1 (en) | 1998-06-11 |
| ITMI962545A0 (it) | 1996-12-04 |
| ZA9710862B (en) | 1998-06-23 |
| JP2000505114A (ja) | 2000-04-25 |
| EP0901460B1 (de) | 2002-09-18 |
| CA2244884A1 (en) | 1998-06-11 |
| IN185038B (de) | 2000-10-21 |
| JP4219409B2 (ja) | 2009-02-04 |
| NO983563L (no) | 1998-10-02 |
| DE901460T1 (de) | 1999-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |