ZA964894B - Immunological combination compositions and methods. - Google Patents
Immunological combination compositions and methods.Info
- Publication number
- ZA964894B ZA964894B ZA9604894A ZA964894A ZA964894B ZA 964894 B ZA964894 B ZA 964894B ZA 9604894 A ZA9604894 A ZA 9604894A ZA 964894 A ZA964894 A ZA 964894A ZA 964894 B ZA964894 B ZA 964894B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- lipoprotein
- compositions
- antigen
- combination compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000001900 immune effect Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 108090001030 Lipoproteins Proteins 0.000 abstract 2
- 102000004895 Lipoproteins Human genes 0.000 abstract 2
- 108700006640 OspA Proteins 0.000 abstract 2
- 102000057248 Lipoprotein(a) Human genes 0.000 abstract 1
- 108010033266 Lipoprotein(a) Proteins 0.000 abstract 1
- 108700023315 OspC Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 230000029226 lipidation Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/828—Bacterial vaccine for canidae or mustelidae, e.g. dogs, foxes, minks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/476,656 US6251405B1 (en) | 1995-06-07 | 1995-06-07 | Immunological combination compositions and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA964894B true ZA964894B (en) | 1997-02-24 |
Family
ID=23892726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9604894A ZA964894B (en) | 1995-06-07 | 1996-06-07 | Immunological combination compositions and methods. |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US6251405B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP0831937B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPH11510370A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE249844T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU717890B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2223041A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69630033T2 (cg-RX-API-DMAC7.html) |
| FI (1) | FI118591B (cg-RX-API-DMAC7.html) |
| IL (1) | IL118579A (cg-RX-API-DMAC7.html) |
| NO (1) | NO975620L (cg-RX-API-DMAC7.html) |
| WO (1) | WO1996040290A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA964894B (cg-RX-API-DMAC7.html) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| ZA964896B (en) * | 1995-06-07 | 1997-01-08 | Connaught Lab | Expression of lipoproteins |
| ATE221770T1 (de) * | 1997-05-14 | 2002-08-15 | Galen Chemicals Ltd | Topische mittel |
| AU9574598A (en) * | 1997-09-18 | 1999-04-05 | Pasteur Merieux Connaught | Improved method of production of pneumococcal surface proteins |
| CA2337823A1 (en) * | 1998-06-26 | 2000-01-06 | Bernard Meignier | Mucosal targeting immunisation |
| DK1126876T3 (da) | 1998-10-16 | 2007-07-02 | Glaxosmithkline Biolog Sa | Adjuvanssystemer og vacciner |
| CA2358385C (en) | 1998-12-31 | 2013-08-06 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| JP2002533124A (ja) | 1998-12-31 | 2002-10-08 | カイロン コーポレイション | Hivポリペプチドの改善された発現およびウイルス様粒子の生成 |
| AT407958B (de) * | 1999-02-11 | 2001-07-25 | Immuno Ag | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
| DK1187629T3 (da) | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
| ATE340262T1 (de) | 1999-06-18 | 2006-10-15 | Univ New York State Res Found | Gruppen von borrelia burgdorferi, die lyme krankheit verursachen |
| EP1235588A2 (en) * | 1999-12-09 | 2002-09-04 | Institut Pasteur | Systemic immune response induced by mucosal administration of lipid-tailed polypeptides without adjuvant |
| US20030232055A1 (en) * | 2000-07-31 | 2003-12-18 | Ruslan Medzhitov | Innate immune system-directed vaccines |
| EP1322326A4 (en) * | 2000-07-31 | 2005-08-17 | Univ Yale | VACCINES DIRECTED TO THE INNE IMMUNE SYSTEM |
| PT1311540E (pt) | 2000-08-18 | 2008-03-20 | Univ New York State Res Found | Ospa de borrelia burgdorferi modificada |
| EP1939294A1 (en) | 2000-08-18 | 2008-07-02 | Research Foundation Of State University Of New York | Recombinant constructs of borrelia burgdorferi |
| US20030175287A1 (en) * | 2001-01-03 | 2003-09-18 | Yale University | Innate immune system-directed vaccines |
| AU2002320314A1 (en) | 2001-07-05 | 2003-01-21 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| US7923023B2 (en) * | 2002-02-25 | 2011-04-12 | Astech International LLC | Method and composition for delivery of medicants to animals |
| US20080299140A1 (en) * | 2002-05-24 | 2008-12-04 | The Regents Of The University Of California, | Immunogenic Composition and Peptide Sequences for Prevention and Treatment of an Hsv Condition |
| FR2846004B1 (fr) * | 2002-10-16 | 2006-06-23 | Maco Pharma Sa | Composition pour culture de cellules notamment animales ou de tissus, comprenant du polyethylene glycol |
| WO2005115430A1 (en) * | 2004-05-27 | 2005-12-08 | Gropep Limited | Treatment of inflammatory airway disease |
| US8029777B2 (en) * | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
| EP1789094B1 (en) | 2004-08-13 | 2014-12-10 | MARSHALL, Barry J. | Bacterial delivery system |
| EP2476432B1 (en) | 2006-03-07 | 2015-08-19 | Vaxinnate Corporation | Compositions that include hemagglutinin, methods of making and methods of use thereof |
| RU2348406C1 (ru) * | 2007-05-02 | 2009-03-10 | Федеральное Государственное Учреждение НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИУТ ДЕТСКИХ ИНФЕКЦИЙ | Способ лечения бактериальных гнойных менингитов у детей |
| US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| TWI376385B (en) * | 2007-12-07 | 2012-11-11 | Nat Health Research Institutes | Production of lipidated proteins in e. coli |
| US20110105355A1 (en) | 2008-04-22 | 2011-05-05 | Research Foundation Of State University Of New York | Borrelia burgdorferi cell envelope protein array |
| US8287880B2 (en) | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| CN102482327B (zh) * | 2009-06-22 | 2014-10-29 | 财团法人卫生研究院 | 脂质化肿瘤相关抗原及其免疫治疗的组成物及方法 |
| SG178904A1 (en) * | 2009-09-10 | 2012-04-27 | Novartis Ag | Combination vaccines against respiratory tract diseases |
| TW201221642A (en) | 2010-11-15 | 2012-06-01 | Nat Health Research Institutes | Method of producing lipidated polypeptides |
| TWI507413B (zh) | 2010-11-15 | 2015-11-11 | Nat Health Research Institutes | 脂質化多抗原表位疫苗 |
| CA2823325C (en) | 2010-12-29 | 2017-09-26 | Oceanspar, Inc. | Center spar fish pen |
| KR20160088323A (ko) * | 2013-12-03 | 2016-07-25 | 비로메틱스 아게 | S. 뉴모니에(S. pneumoniae)에 대항하는 보호성 프롤린-풍부한 펩티드 |
| WO2016057562A1 (en) | 2014-10-07 | 2016-04-14 | The Research Foundation For The State University Of New York | Recombinant borrelia proteins and methods of use thereof |
| WO2025015077A1 (en) * | 2023-07-10 | 2025-01-16 | Dynavax Technologies Corporation | Lyme disease vaccines comprising an adjuvant and borrelia outer surface protein a and c antigens |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK590288D0 (da) * | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| US4302386A (en) * | 1978-08-25 | 1981-11-24 | The Ohio State University | Antigenic modification of polypeptides |
| EP0014815A3 (de) | 1978-12-20 | 1980-10-29 | Ciba-Geigy Ag | Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen |
| US4258029A (en) | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US4455142A (en) | 1980-07-07 | 1984-06-19 | Alza Corporation | Method of coadministering an antigen and an immunopotentiator |
| US4484923A (en) * | 1982-03-25 | 1984-11-27 | Alza Corporation | Method for administering immunopotentiator |
| DE3521994A1 (de) | 1985-06-20 | 1987-01-02 | Bayer Ag | N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| US4839293A (en) * | 1986-02-24 | 1989-06-13 | The Trustees Of Columbia University In The City Of New York | DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include amino acid sequences present in streptavidin and uses thereof |
| US4721617A (en) | 1986-08-14 | 1988-01-26 | Regents Of The University Of Minnesota | Vaccine against lyme disease |
| EP0270295A3 (en) * | 1986-12-03 | 1989-08-02 | Connaught Laboratories Limited | Conjugate vaccine |
| US4879213A (en) * | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
| US5098997A (en) * | 1987-12-11 | 1992-03-24 | Praxis Biologics, Inc. | Vaccines for Haemophilus influenzae |
| AU4338489A (en) | 1988-09-20 | 1990-04-18 | Marvin Murray | Accelerated microdilution determination of bacteria susceptibility to antibiotics |
| CA2072008C (en) | 1989-12-22 | 2003-01-28 | Renate Fuchs | Immunologically active proteins from borrelia burgdorferi, related test kits which contain these proteins and are suitable for detecting antibodies in test fluids, and the use of these proteins as vaccines against infections caused by borrelia strains |
| CA2032914A1 (en) * | 1989-12-26 | 1991-06-27 | Peter C.K. Lau | Use of bacterial lipoprotein amino terminus in fusion plasmids for in vivo expression of lipid modified polypeptides |
| ATE168132T1 (de) | 1991-02-15 | 1998-07-15 | Uab Research Foundation | Strukturgen von pneumokokken-protein |
| DK0598816T3 (da) * | 1991-08-15 | 1999-11-22 | Deutsches Krebsforsch | Osp A-proteiner fra Borrelia Burgdorferi-undergrupper, hvilke proteiner koder for gener og vacciner |
| JPH07502646A (ja) * | 1991-10-21 | 1995-03-23 | メディミューン,インコーポレーテッド | リポタンパク質の分泌シグナルをコード化するdnaを含む細菌発現ベクター |
| ATE234365T1 (de) * | 1991-10-22 | 2003-03-15 | Symbicom Ab | Verbesserungen der diagnose und der prophylaxe von borrelia burgdorferi |
| CA2105629A1 (en) * | 1992-09-14 | 1994-03-15 | Robert S. Becker | Potentiation of immunogenic response |
| WO1994014318A1 (en) * | 1992-12-24 | 1994-07-07 | Medimmune, Inc. | Method of protection against streptococcus pneumoniae with transformed mycobacteria |
| FR2708622B1 (fr) * | 1993-08-02 | 1997-04-18 | Raymond Hamers | Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides. |
-
1995
- 1995-06-07 US US08/476,656 patent/US6251405B1/en not_active Expired - Fee Related
-
1996
- 1996-01-19 US US08/588,621 patent/US6379675B1/en not_active Expired - Fee Related
- 1996-06-05 CA CA002223041A patent/CA2223041A1/en not_active Abandoned
- 1996-06-05 WO PCT/US1996/008866 patent/WO1996040290A1/en not_active Ceased
- 1996-06-05 JP JP9501336A patent/JPH11510370A/ja not_active Ceased
- 1996-06-05 IL IL118579A patent/IL118579A/en not_active IP Right Cessation
- 1996-06-05 AT AT96919085T patent/ATE249844T1/de not_active IP Right Cessation
- 1996-06-05 DE DE69630033T patent/DE69630033T2/de not_active Expired - Fee Related
- 1996-06-05 AU AU61519/96A patent/AU717890B2/en not_active Ceased
- 1996-06-05 EP EP96919085A patent/EP0831937B1/en not_active Expired - Lifetime
- 1996-06-07 ZA ZA9604894A patent/ZA964894B/xx unknown
-
1997
- 1997-12-04 NO NO975620A patent/NO975620L/no unknown
- 1997-12-05 FI FI974423A patent/FI118591B/fi active IP Right Grant
-
2002
- 2002-03-12 US US10/096,687 patent/US6984385B2/en not_active Expired - Fee Related
-
2005
- 2005-07-01 US US11/173,364 patent/US7235243B2/en not_active Expired - Fee Related
-
2007
- 2007-05-18 US US11/804,446 patent/US20080089911A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080089911A1 (en) | 2008-04-17 |
| EP0831937B1 (en) | 2003-09-17 |
| ATE249844T1 (de) | 2003-10-15 |
| US6984385B2 (en) | 2006-01-10 |
| US7235243B2 (en) | 2007-06-26 |
| US20020131983A1 (en) | 2002-09-19 |
| NO975620L (no) | 1998-02-04 |
| EP0831937A1 (en) | 1998-04-01 |
| JPH11510370A (ja) | 1999-09-14 |
| AU6151996A (en) | 1996-12-30 |
| AU717890B2 (en) | 2000-04-06 |
| IL118579A (en) | 2007-12-03 |
| US6379675B1 (en) | 2002-04-30 |
| IL118579A0 (en) | 1996-10-16 |
| US20060110408A1 (en) | 2006-05-25 |
| EP0831937A4 (en) | 2001-09-19 |
| DE69630033D1 (de) | 2003-10-23 |
| FI118591B (fi) | 2008-01-15 |
| NO975620D0 (no) | 1997-12-04 |
| US6251405B1 (en) | 2001-06-26 |
| DE69630033T2 (de) | 2004-04-01 |
| FI974423L (fi) | 1998-02-04 |
| CA2223041A1 (en) | 1996-12-19 |
| WO1996040290A1 (en) | 1996-12-19 |
| FI974423A0 (fi) | 1997-12-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL118579A0 (en) | Immunological combination compositions and methods | |
| CA2177668A1 (en) | Mammalian vaccine compositions comprising squalene or squalane, glycerol and a surfactant as an adjuvant | |
| CA2082155A1 (en) | Swine pneumonia vaccine and method of preparation | |
| CA2217178A1 (en) | Vaccines containing a saponin and a sterol | |
| IS4518A (is) | Nýtt lyfjaform fyrir bóluefni | |
| HUP9900925A2 (hu) | Napfényt szűrő készítmények | |
| FR2686896B1 (fr) | Mutant attenue de listeria monocytogenes; souche recombinante de listeria monocytogenes, utilisation comme vecteurs heterologues d'antigenes vaccinal et utilisation comme vaccin ou composition diagnostique. | |
| CA2138997A1 (en) | Vaccine composition containing adjuvants | |
| MX9803290A (es) | Composiciones de la vacuna influenza. | |
| EE03569B1 (et) | Mikrovedeldatud adjuvantkompositsioonid antigeenspetsiifilise tsütotoksiliste T-lümfotsüütide vastuse indutseerimiseks | |
| EP1955709A3 (en) | Adjuvant compositions for enhancing immune responses to polynucleotide-based vaccines | |
| CA2302554A1 (en) | Oil in water emulsions containing saponins | |
| CA2086094A1 (en) | Vaccine compositions containing liposomes | |
| EP2275122A3 (en) | Protein-based streptococcus pneumoniae vaccines | |
| DE69623072D1 (de) | Impfstoffzusammensetzung für Säugetiere enthaltend Squalen oder Squalan, Phospholipid und ein Tensid als Adjuvans | |
| PT789590E (pt) | Imunopotenciacao induzida por quitosano | |
| WO2001097841A3 (en) | Qs-21 and il-12 as an adjuvant combination | |
| FI972054A0 (fi) | Immunogeenisiä koostumuksia | |
| GEP20053446B (en) | Adjuvant Combination Formulations | |
| GB9501826D0 (en) | Polypeptide fragments | |
| DK0757556T3 (da) | Borrelia Burgdorferi-bakterin | |
| SE9604322D0 (sv) | Bacterial antigens and vaccine compositions II | |
| GB9500788D0 (en) | Vaccine compositions | |
| AU4537100A (en) | Adjuvant combinations for immunization composition and vaccines | |
| CA2273922A1 (en) | Novel saponin compositions and uses thereof |