ATE234365T1 - Verbesserungen der diagnose und der prophylaxe von borrelia burgdorferi - Google Patents
Verbesserungen der diagnose und der prophylaxe von borrelia burgdorferiInfo
- Publication number
- ATE234365T1 ATE234365T1 AT92922907T AT92922907T ATE234365T1 AT E234365 T1 ATE234365 T1 AT E234365T1 AT 92922907 T AT92922907 T AT 92922907T AT 92922907 T AT92922907 T AT 92922907T AT E234365 T1 ATE234365 T1 AT E234365T1
- Authority
- AT
- Austria
- Prior art keywords
- burgdorferi
- specimen
- detecting
- ospb
- borrelia burgdorferi
- Prior art date
Links
- 241000589969 Borreliella burgdorferi Species 0.000 title abstract 6
- 238000003745 diagnosis Methods 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108700006640 OspA Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 235000012601 Euterpe oleracea Nutrition 0.000 abstract 1
- 244000207620 Euterpe oleracea Species 0.000 abstract 1
- 208000016604 Lyme disease Diseases 0.000 abstract 1
- 235000003650 acai Nutrition 0.000 abstract 1
- 230000000763 evoking effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77918591A | 1991-10-22 | 1991-10-22 | |
| PCT/US1992/008972 WO1993008306A1 (en) | 1991-10-22 | 1992-10-22 | Improvement in borrelia burgdorferi diagnosis and prophylaxis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234365T1 true ATE234365T1 (de) | 2003-03-15 |
Family
ID=25115605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92922907T ATE234365T1 (de) | 1991-10-22 | 1992-10-22 | Verbesserungen der diagnose und der prophylaxe von borrelia burgdorferi |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP0650527B1 (de) |
| AT (1) | ATE234365T1 (de) |
| AU (1) | AU2903892A (de) |
| DE (1) | DE69232956T2 (de) |
| DK (1) | DK0650527T3 (de) |
| ES (1) | ES2194010T3 (de) |
| WO (1) | WO1993008306A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6054296A (en) * | 1988-10-24 | 2000-04-25 | Symbicom Ab | 66 kDa antigen from Borrelia |
| US6676942B1 (en) | 1991-08-15 | 2004-01-13 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| DE69229476T2 (de) * | 1991-08-15 | 2000-03-16 | Smithkline Beecham Biolog | Ospa proteine von borrelia burgdorferi untergruppen, dafür kodierende gene sowie impfstoffe |
| BE1006728A3 (fr) * | 1993-02-19 | 1994-11-29 | Wallone Region | Sondes d'acides nucleiques specifiques au spirochete borrelia burgdorferi. |
| EP0686265A4 (de) * | 1993-02-26 | 2001-08-22 | Cambridge Biotech Corp | Verfahren zum induzieren von immunität gegen die lyme-krankheit und ein kolorimetrischer test auf borreliazide aktivität von antisera |
| US6716591B1 (en) | 1993-07-30 | 2004-04-06 | Yale University | B. burgdorferi polypeptides |
| US5656451A (en) * | 1993-07-30 | 1997-08-12 | Yale University | OspE, OspF, and S1 polypeptides in borrelia burgdorferi |
| US6248562B1 (en) | 1993-11-01 | 2001-06-19 | Research Foundation State University Of New York | Chimeric proteins comprising borrelia polypeptides and uses therefor |
| PT726955E (pt) * | 1993-11-01 | 2004-08-31 | Brookhaven Science Ass Llc | Proteinas quimericas compreendendo polipeptidos borrelia: suas utilizacoes |
| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| CA2187535C (en) * | 1994-04-11 | 2011-09-13 | Jon B. Korshus | Borrelia burgdorferi bacterin |
| US6087097A (en) * | 1994-05-12 | 2000-07-11 | Mayo Foundation For Medical Education And Research | PCR detection of Borrelia burgdorferi |
| EP1741718A3 (de) * | 1995-06-07 | 2007-03-28 | Sanofi Pasteur Inc. | Expression von lipoproteinen |
| US6251405B1 (en) * | 1995-06-07 | 2001-06-26 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
| ZA964896B (en) | 1995-06-07 | 1997-01-08 | Connaught Lab | Expression of lipoproteins |
| DE19605475C1 (de) * | 1996-02-14 | 1997-11-20 | Deutsches Krebsforsch | Verfahren zur Erkennung des Erkrankungsrisikos nach Arthropodenstich |
| US6045804A (en) * | 1996-03-07 | 2000-04-04 | Mayo Foundation For Medical Educational Research | Method for detecting B. burgdorferi infection |
| DE19632862B4 (de) | 1996-08-14 | 2006-08-03 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologisch aktive Proteine von Borrelia burgdorferi, dafür kodierende Nukleinsäuren sowie deren Verwendung in Testkits und als Impfstoffe |
| CA2300365A1 (en) * | 1997-09-10 | 1999-03-18 | Symbicom Aktiebolag | P13 antigens from borrelia |
| US6224882B1 (en) | 1997-11-07 | 2001-05-01 | Protein Science Corp. | Insect cells or fractions as adjuvant for antigens |
| DE60131982T2 (de) | 2000-08-18 | 2008-12-11 | Brookhaven Science Associates Llc | Veränderte borrelia burgdorferi ospa |
| TWI367109B (en) | 2006-01-19 | 2012-07-01 | Mary Kay Inc | Compositions comprising kakadu plum extract or acai berry extract |
| KR101192127B1 (ko) | 2006-11-03 | 2012-10-17 | 쉐링-프라우 리미티드 | 개 라임병 백신 |
| WO2008116468A2 (en) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| EP3023436A1 (de) | 2007-07-03 | 2016-05-25 | Dako Denmark A/S | Verbesserte verfahren zur herstellung, markierung und verwendung von mhc-multimeren |
| EP2197908A2 (de) | 2007-09-27 | 2010-06-23 | Dako Denmark A/S | Mhc-multimere in tuberkulose-diagnostika, -impfstoff und therapeutika |
| US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
| EP2288381A2 (de) | 2008-05-02 | 2011-03-02 | Cancer Research Technology Limited | Produkte und verfahren zur stimulation einer immunantwort |
| WO2010009735A2 (en) | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| EP2470159A1 (de) | 2009-08-28 | 2012-07-04 | Mary Kay, Inc. | Hautpflegeformulierungen |
| EA025280B1 (ru) | 2010-03-09 | 2016-12-30 | Амир Максютов | Полиэпитопные конструкции и способы их получения и применения |
| WO2012023033A2 (en) | 2010-08-18 | 2012-02-23 | Purdue Pharma L.P. | Improved peptide immunogens |
| EP2805168B1 (de) | 2012-01-20 | 2018-03-07 | The Government Of The U.S.A. As Represented By The Secretary Of Health And Human Services, Centers For Disease Control And Prevention | Zusammensetzungen und verfahren im zusammenhang mit lyme-borreliose |
| WO2023240109A1 (en) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Multispecific molecules for modulating t-cell activity, and uses thereof |
| WO2023240124A1 (en) | 2022-06-07 | 2023-12-14 | Regeneron Pharmaceuticals, Inc. | Pseudotyped viral particles for targeting tcr-expressing cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK590288D0 (da) * | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| DE4015911A1 (de) * | 1989-09-19 | 1991-03-28 | Max Planck Gesellschaft | Impfstoff gegen die lyme-krankheit |
| WO1992000055A1 (en) * | 1990-06-15 | 1992-01-09 | Yale University | Compositions and methods for the prevention and diagnosis of lyme disease |
-
1992
- 1992-10-22 EP EP92922907A patent/EP0650527B1/de not_active Expired - Lifetime
- 1992-10-22 AT AT92922907T patent/ATE234365T1/de active
- 1992-10-22 DK DK92922907T patent/DK0650527T3/da active
- 1992-10-22 DE DE69232956T patent/DE69232956T2/de not_active Expired - Lifetime
- 1992-10-22 EP EP92610073A patent/EP0540457A1/de not_active Withdrawn
- 1992-10-22 ES ES92922907T patent/ES2194010T3/es not_active Expired - Lifetime
- 1992-10-22 AU AU29038/92A patent/AU2903892A/en not_active Abandoned
- 1992-10-22 WO PCT/US1992/008972 patent/WO1993008306A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO1993008306A1 (en) | 1993-04-29 |
| EP0650527A1 (de) | 1995-05-03 |
| DE69232956T2 (de) | 2003-10-02 |
| EP0650527B1 (de) | 2003-03-12 |
| ES2194010T3 (es) | 2003-11-16 |
| DE69232956D1 (de) | 2003-04-17 |
| AU2903892A (en) | 1993-05-21 |
| DK0650527T3 (da) | 2003-07-14 |
| EP0540457A1 (de) | 1993-05-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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