ZA961697B - Indole derivatives. - Google Patents

Indole derivatives.

Info

Publication number
ZA961697B
ZA961697B ZA9601697A ZA961697A ZA961697B ZA 961697 B ZA961697 B ZA 961697B ZA 9601697 A ZA9601697 A ZA 9601697A ZA 961697 A ZA961697 A ZA 961697A ZA 961697 B ZA961697 B ZA 961697B
Authority
ZA
South Africa
Prior art keywords
indole derivatives
indole
derivatives
Prior art date
Application number
ZA9601697A
Other languages
English (en)
Inventor
Nadia Conti
Romano Di Fabio
Elisabetta De Magistris
Aldo Feriani
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Publication of ZA961697B publication Critical patent/ZA961697B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9601697A 1995-03-04 1996-03-01 Indole derivatives. ZA961697B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9504361.8A GB9504361D0 (en) 1995-03-04 1995-03-04 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
ZA961697B true ZA961697B (en) 1997-10-01

Family

ID=10770638

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9601697A ZA961697B (en) 1995-03-04 1996-03-01 Indole derivatives.

Country Status (23)

Country Link
US (1) US5919811A (fr)
EP (1) EP0813524A1 (fr)
JP (1) JPH11501041A (fr)
KR (1) KR19980702735A (fr)
CN (1) CN1182417A (fr)
AR (1) AR002711A1 (fr)
AU (1) AU708291B2 (fr)
BR (1) BR9607346A (fr)
CA (1) CA2214583A1 (fr)
CO (1) CO4700452A1 (fr)
CZ (1) CZ277997A3 (fr)
EA (1) EA000308B1 (fr)
GB (1) GB9504361D0 (fr)
HU (1) HUP9801838A3 (fr)
IL (1) IL117331A (fr)
MX (1) MX9706605A (fr)
NO (1) NO309323B1 (fr)
NZ (1) NZ303200A (fr)
PE (1) PE62396A1 (fr)
PL (1) PL322084A1 (fr)
TW (1) TW438773B (fr)
WO (1) WO1996027588A1 (fr)
ZA (1) ZA961697B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5886191A (en) * 1997-08-18 1999-03-23 Dupont Pharmaceuticals Company Amidinoindoles, amidinoazoles, and analogs thereof
GB9902455D0 (en) * 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
CA2468544A1 (fr) * 2001-12-10 2003-06-19 Amgen Inc. Ligands de recepteur vanilloide et utilisation de ceux-ci dans des traitements
GB0205176D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
JP4613157B2 (ja) * 2003-01-14 2011-01-12 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
EP1765327B1 (fr) 2004-06-17 2014-08-13 Cytokinetics, Inc. Composes, compositions et procedes associes
US7176222B2 (en) 2004-07-27 2007-02-13 Cytokinetics, Inc. Syntheses of ureas
US7538223B2 (en) * 2005-08-04 2009-05-26 Cytokinetics, Inc. Compounds, compositions and methods
AR058347A1 (es) * 2005-12-15 2008-01-30 Cytokinetics Inc Entidades quimias composiciones y metodos
US20070208000A1 (en) * 2005-12-15 2007-09-06 Morgan Bradley P Certain chemical entities, compositions and methods
US20070197505A1 (en) * 2005-12-15 2007-08-23 Morgan Bradley P Certain chemical entities, compositions and methods
US7825120B2 (en) * 2005-12-15 2010-11-02 Cytokinetics, Inc. Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
US7718657B2 (en) 2005-12-16 2010-05-18 Cytokinetics, Inc. Certain indanyl urea modulators of the cardiac sarcomere
WO2007078839A2 (fr) * 2005-12-19 2007-07-12 Cytokinetics, Inc. Composes, compositions et methodes
WO2009035927A2 (fr) * 2007-09-13 2009-03-19 Arete Therapeutics, Inc. Inhibiteurs de l'époxyde hydrolase soluble
PE20091101A1 (es) 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
PL2445915T3 (pl) 2009-06-23 2016-10-31 Związki 3-podstawionego-8-podstawionego-3H imidazo[5,1-d][1,2,3,5 tetrazyn]-4-onu i ich zastosowanie
EP2542553A1 (fr) 2010-03-01 2013-01-09 Pharminox Ltd Procédés et intermédiaires pour effectuer la synthèse de 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tétrazines
WO2012085501A1 (fr) 2010-12-20 2012-06-28 Pharminox Limited Composés 8-sulfo-imidazotétrazin-4-one et leur utilisation en tant que médicament anticancéreux
TW202128630A (zh) 2019-11-11 2021-08-01 荷蘭商卡普三世責任有限公司 工業規模上用於生產ε-己內醯胺及硫酸銨之方法及設備

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145845A (en) * 1991-05-14 1992-09-08 Warner-Lambert Co. Substituted 2-carboxylindoles having pharmaceutical activity
GB9208492D0 (en) * 1992-04-16 1992-06-03 Glaxo Spa Heterocyclic compounds
GB9304500D0 (en) * 1993-03-05 1993-04-21 Glaxo Spa Heterocyclic compounds
US5519048A (en) * 1993-05-27 1996-05-21 Merrell Pharmaceuticals Inc. 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
EP0813524A1 (fr) 1997-12-29
PE62396A1 (es) 1997-01-11
US5919811A (en) 1999-07-06
EA199700160A1 (ru) 1998-02-26
AU4943896A (en) 1996-09-23
AR002711A1 (es) 1998-04-29
IL117331A (en) 2000-06-29
HUP9801838A2 (hu) 1998-12-28
NO974043D0 (no) 1997-09-03
NO309323B1 (no) 2001-01-15
CO4700452A1 (es) 1998-12-29
AU708291B2 (en) 1999-07-29
MX9706605A (es) 1998-02-28
PL322084A1 (en) 1998-01-05
BR9607346A (pt) 1997-12-30
HUP9801838A3 (en) 2000-04-28
WO1996027588A1 (fr) 1996-09-12
TW438773B (en) 2001-06-07
CN1182417A (zh) 1998-05-20
NZ303200A (en) 1999-01-28
GB9504361D0 (en) 1995-04-26
EA000308B1 (ru) 1999-04-29
JPH11501041A (ja) 1999-01-26
IL117331A0 (en) 1996-07-23
NO974043L (no) 1997-11-03
CZ277997A3 (cs) 1998-06-17
KR19980702735A (ko) 1998-08-05
CA2214583A1 (fr) 1996-09-12

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