ZA9610687B - Novel synthesis. - Google Patents
Novel synthesis.Info
- Publication number
- ZA9610687B ZA9610687B ZA9610687A ZA9610687A ZA9610687B ZA 9610687 B ZA9610687 B ZA 9610687B ZA 9610687 A ZA9610687 A ZA 9610687A ZA 9610687 A ZA9610687 A ZA 9610687A ZA 9610687 B ZA9610687 B ZA 9610687B
- Authority
- ZA
- South Africa
- Prior art keywords
- novel synthesis
- synthesis
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Resins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US909895P | 1995-12-22 | 1995-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA9610687B true ZA9610687B (en) | 1997-09-29 |
Family
ID=21735553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9610687A ZA9610687B (en) | 1995-12-22 | 1996-12-19 | Novel synthesis. |
Country Status (18)
Country | Link |
---|---|
US (3) | US5917043A (ja) |
EP (1) | EP1019393A4 (ja) |
JP (1) | JP3245175B2 (ja) |
KR (1) | KR19990076625A (ja) |
CN (1) | CN1209128A (ja) |
AR (3) | AR004405A1 (ja) |
AU (1) | AU704500B2 (ja) |
BR (1) | BR9612187A (ja) |
CZ (1) | CZ198598A3 (ja) |
HU (1) | HUP9902466A3 (ja) |
IL (2) | IL143517A (ja) |
NO (1) | NO982850D0 (ja) |
NZ (1) | NZ326574A (ja) |
PL (1) | PL327311A1 (ja) |
TR (1) | TR199801121T2 (ja) |
TW (1) | TW434236B (ja) |
WO (1) | WO1997023479A1 (ja) |
ZA (1) | ZA9610687B (ja) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5916891A (en) | 1992-01-13 | 1999-06-29 | Smithkline Beecham Corporation | Pyrimidinyl imidazoles |
ZA9610687B (en) * | 1995-12-22 | 1997-09-29 | Smithkline Beecham Corp | Novel synthesis. |
JP2000503302A (ja) * | 1996-01-11 | 2000-03-21 | スミスクライン・ビーチャム・コーポレイション | 新規置換イミダゾール化合物 |
ZA9711092B (en) * | 1996-12-11 | 1999-07-22 | Smithkline Beecham Corp | Novel compounds. |
AU7726898A (en) | 1997-05-22 | 1998-12-11 | G.D. Searle & Co. | Pyrazole derivatives as p38 kinase inhibitors |
US6514977B1 (en) | 1997-05-22 | 2003-02-04 | G.D. Searle & Company | Substituted pyrazoles as p38 kinase inhibitors |
US6979686B1 (en) | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
AU7966198A (en) | 1997-06-13 | 1998-12-30 | Smithkline Beecham Corporation | Novel pyrazole and pyrazoline substituted compounds |
US6610695B1 (en) | 1997-06-19 | 2003-08-26 | Smithkline Beecham Corporation | Aryloxy substituted pyrimidine imidazole compounds |
US6562832B1 (en) | 1997-07-02 | 2003-05-13 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US7301021B2 (en) | 1997-07-02 | 2007-11-27 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US6489325B1 (en) | 1998-07-01 | 2002-12-03 | Smithkline Beecham Corporation | Substituted imidazole compounds |
EP1041989A4 (en) | 1997-10-08 | 2002-11-20 | Smithkline Beecham Corp | NEW SUBSTITUTED CYCLOALCENYL COMPOUNDS |
WO1999032121A1 (en) | 1997-12-19 | 1999-07-01 | Smithkline Beecham Corporation | Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses |
US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
CA2341370A1 (en) | 1998-08-20 | 2000-03-02 | Smithkline Beecham Corporation | Novel substituted triazole compounds |
EP1126852B1 (en) * | 1998-11-04 | 2004-01-21 | SmithKline Beecham Corporation | Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines |
US6239279B1 (en) * | 1998-12-16 | 2001-05-29 | Smithkline Beecham Corporation | Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives |
US20050274801A1 (en) * | 1999-01-29 | 2005-12-15 | Intermec Ip Corp. | Method, apparatus and article for validating ADC devices, such as barcode, RFID and magnetic stripe readers |
US6857013B2 (en) * | 1999-01-29 | 2005-02-15 | Intermec Ip.Corp. | Remote anomaly diagnosis and reconfiguration of an automatic data collection device platform over a telecommunications network |
US7122666B2 (en) | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
US6976062B1 (en) * | 1999-09-22 | 2005-12-13 | Intermec Ip Corp. | Automated software upgrade utility |
US6759410B1 (en) | 1999-11-23 | 2004-07-06 | Smithline Beecham Corporation | 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors |
JP2003528043A (ja) | 1999-11-23 | 2003-09-24 | スミスクライン・ビーチャム・コーポレイション | CSBP/p38キナーゼ阻害剤としての3,4‐ジヒドロ−(1H)キナゾリン−2−オン化合物 |
DE60015599T2 (de) | 1999-11-23 | 2005-11-03 | Smithkline Beecham Corp. | 3,4-DIHYDRO-(1H)CHINAZOLIN-2-ON-VERBINDUNGEN ALS CSBP/p38-KINASE-INHIBITOREN |
JP2003514900A (ja) | 1999-11-23 | 2003-04-22 | スミスクライン・ビーチャム・コーポレイション | CSBP/p38キナーゼ阻害剤としての3,4−ジヒドロ−(1H)−キナゾリン−2−オン化合物 |
US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
IL155367A0 (en) * | 2000-10-23 | 2003-12-23 | Smithkline Beecham Corp | NOVEL 2,4,8-TRISUBSTITUTED-8h-PYRIDO[2,3,-d]PYRIMIDIN-7-ONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE PREPARATION OF MEDICAMENTS FOR TREATING CSBP/p38 KINASE MEDIATED DISEASES |
ATE377598T1 (de) | 2001-01-22 | 2007-11-15 | Sankyo Co | Durch bicyclische aminogruppen substituierte verbindungen |
WO2002094267A1 (fr) * | 2001-05-24 | 2002-11-28 | Sankyo Company, Limited | Preparation pharmaceutique pour prevenir ou traiter l'arthrite |
AR039241A1 (es) * | 2002-04-04 | 2005-02-16 | Biogen Inc | Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos |
UA80295C2 (en) * | 2002-09-06 | 2007-09-10 | Biogen Inc | Pyrazolopyridines and using the same |
CL2004000234A1 (es) * | 2003-02-12 | 2005-04-15 | Biogen Idec Inc | Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid |
PE20100737A1 (es) | 2005-03-25 | 2010-11-27 | Glaxo Group Ltd | Nuevos compuestos |
EP1865959A2 (en) * | 2005-03-25 | 2007-12-19 | Glaxo Group Limited | Process for preparing pyridoý2,3-d¨pyrimidin-7-one and 3,4-dihydropyrimidoý4,5-d¨pyrimidin-2(1h)-one derivatives |
US8944332B2 (en) | 2006-08-04 | 2015-02-03 | Intermec Ip Corp. | Testing automatic data collection devices, such as barcode, RFID and/or magnetic stripe readers |
WO2019168874A1 (en) | 2018-02-27 | 2019-09-06 | The Research Foundation For The State University Of New York | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2748119A (en) * | 1954-06-23 | 1956-05-29 | Searle & Co | 6-furyl and 6-thienyl derivatives of 4-trifluoromethyl-2-pyrimidinamines |
US3557114A (en) * | 1968-12-23 | 1971-01-19 | Merck & Co Inc | 1-substituted-3-(2-pyrimidinyl) imidazolium salts |
US3707475A (en) * | 1970-11-16 | 1972-12-26 | Pfizer | Antiinflammatory imidazoles |
US3929807A (en) * | 1971-05-10 | 1975-12-30 | Ciba Geigy Corp | 2-Substituted-4(5)-(aryl)-5(4)-(2,3 or -4-pyridyl)-imidazoles |
US3940486A (en) * | 1971-05-10 | 1976-02-24 | Ciba-Geigy Corporation | Imidazole derivatives in the treatment of pain |
US4058614A (en) * | 1973-12-04 | 1977-11-15 | Merck & Co., Inc. | Substituted imidazole compounds and therapeutic compositions therewith |
US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
DD201677A5 (de) * | 1980-07-25 | 1983-08-03 | Ciba Geigy | Verfahren zur herstellung von trisubstituierten imidazolderivaten |
US4503065A (en) * | 1982-08-03 | 1985-03-05 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl 1-2-halo imidazoles |
US4565875A (en) * | 1984-06-27 | 1986-01-21 | Fmc Corporation | Imidazole plant growth regulators |
US4686231A (en) * | 1985-12-12 | 1987-08-11 | Smithkline Beckman Corporation | Inhibition of 5-lipoxygenase products |
SG47583A1 (en) * | 1986-01-13 | 1998-04-17 | American Cyanamid Co | 4,5,6-Substituted-n- (substituted-phenyl) -2- pyrimidinamines |
IL83467A0 (en) * | 1986-08-15 | 1988-01-31 | Fujisawa Pharmaceutical Co | Imidazole derivatives,processes for their preparation and pharmaceutical compositions containing the same |
GB8906965D0 (en) * | 1989-03-28 | 1989-05-10 | Schering Agrochemicals Ltd | Fungicides |
US5312828A (en) * | 1989-06-14 | 1994-05-17 | Finkelstein Joseph A | Substituted imidazoles having angiotensin II receptor blocking activity |
US5234917A (en) * | 1989-12-29 | 1993-08-10 | Finkelstein Joseph A | Substituted 5-(alkyl)carboxamide imidazoles |
EP0565582A4 (en) * | 1990-12-13 | 1995-01-11 | Smithkline Beecham Corp | NOVEL CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUGS. |
AU9169991A (en) * | 1990-12-13 | 1992-07-08 | Smithkline Beecham Corporation | Novel csaids |
IL104369A0 (en) * | 1992-01-13 | 1993-05-13 | Smithkline Beecham Corp | Novel compounds and compositions |
US5656644A (en) * | 1994-07-20 | 1997-08-12 | Smithkline Beecham Corporation | Pyridyl imidazoles |
IL110296A (en) * | 1993-07-16 | 1999-12-31 | Smithkline Beecham Corp | Imidazole compounds process for their preparation and pharmaceutical compositions containing them |
US5670527A (en) * | 1993-07-16 | 1997-09-23 | Smithkline Beecham Corporation | Pyridyl imidazole compounds and compositions |
US5593991A (en) * | 1993-07-16 | 1997-01-14 | Adams; Jerry L. | Imidazole compounds, use and process of making |
US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
US5543520A (en) * | 1993-10-01 | 1996-08-06 | Ciba-Geigy Corporation | Pyrimidine derivatives |
KR100330553B1 (ko) * | 1993-10-01 | 2002-11-27 | 노파르티스 아게 | 약물학적활성피리딘유도체및그의제조방법 |
EP0672035A1 (en) * | 1993-10-01 | 1995-09-20 | Novartis AG | Pyrimidineamine derivatives and processes for the preparation thereof |
JP3588116B2 (ja) * | 1993-10-01 | 2004-11-10 | ノバルティス アクチェンゲゼルシャフト | 薬理活性のピリミジンアミン誘導体およびその製造方法 |
DE4337611A1 (de) * | 1993-11-04 | 1995-05-11 | Boehringer Ingelheim Kg | Neue Benzoylguanidine, ihre Herstellung und ihre Verwendung in Arzneimitteln |
JPH10512264A (ja) * | 1995-01-12 | 1998-11-24 | スミスクライン・ビーチャム・コーポレイション | 新規化合物 |
US5739143A (en) * | 1995-06-07 | 1998-04-14 | Smithkline Beecham Corporation | Imidazole compounds and compositions |
US5658903A (en) * | 1995-06-07 | 1997-08-19 | Smithkline Beecham Corporation | Imidazole compounds, compositions and use |
ZA9610687B (en) * | 1995-12-22 | 1997-09-29 | Smithkline Beecham Corp | Novel synthesis. |
AP9700912A0 (en) * | 1996-01-11 | 1997-01-31 | Smithkline Beecham Corp | Novel cycloalkyl substituted imidazoles |
JP2000503302A (ja) * | 1996-01-11 | 2000-03-21 | スミスクライン・ビーチャム・コーポレイション | 新規置換イミダゾール化合物 |
ZA97175B (en) * | 1996-01-11 | 1997-11-04 | Smithkline Beecham Corp | Novel substituted imidazole compounds. |
WO1997025047A1 (en) * | 1996-01-11 | 1997-07-17 | Smithkline Beecham Corporation | Novel cycloalkyl substituded imidazoles |
EP0889888A4 (en) * | 1996-03-25 | 2003-01-08 | Smithkline Beecham Corp | NEW TREATMENT OF LESIONS IN THE CENTRAL NERVOUS SYSTEM |
EP0889887A4 (en) * | 1996-03-25 | 2003-06-11 | Smithkline Beecham Corp | TREATMENT OF CENTRAL NERVOUS SYSTEM INJURIES |
-
1996
- 1996-12-19 ZA ZA9610687A patent/ZA9610687B/xx unknown
- 1996-12-20 EP EP96945272A patent/EP1019393A4/en not_active Withdrawn
- 1996-12-20 AR ARP960105842A patent/AR004405A1/es unknown
- 1996-12-20 WO PCT/US1996/020599 patent/WO1997023479A1/en not_active Application Discontinuation
- 1996-12-20 KR KR1019980704729A patent/KR19990076625A/ko not_active Application Discontinuation
- 1996-12-20 US US08/771,320 patent/US5917043A/en not_active Expired - Fee Related
- 1996-12-20 IL IL14351796A patent/IL143517A/xx not_active IP Right Cessation
- 1996-12-20 CZ CZ981985A patent/CZ198598A3/cs unknown
- 1996-12-20 US US09/091,799 patent/US6100399A/en not_active Expired - Fee Related
- 1996-12-20 TR TR1998/01121T patent/TR199801121T2/xx unknown
- 1996-12-20 NZ NZ326574A patent/NZ326574A/xx unknown
- 1996-12-20 CN CN96180018A patent/CN1209128A/zh active Pending
- 1996-12-20 AU AU14681/97A patent/AU704500B2/en not_active Ceased
- 1996-12-20 BR BR9612187A patent/BR9612187A/pt not_active Application Discontinuation
- 1996-12-20 IL IL12490896A patent/IL124908A/xx not_active IP Right Cessation
- 1996-12-20 JP JP52385597A patent/JP3245175B2/ja not_active Expired - Fee Related
- 1996-12-20 PL PL96327311A patent/PL327311A1/xx unknown
- 1996-12-20 HU HU9902466A patent/HUP9902466A3/hu unknown
-
1997
- 1997-08-22 TW TW086112050A patent/TW434236B/zh not_active IP Right Cessation
-
1998
- 1998-03-30 AR ARP980101441A patent/AR012567A1/es not_active Application Discontinuation
- 1998-03-30 AR ARP980101440A patent/AR015579A1/es not_active Application Discontinuation
- 1998-06-19 NO NO982850A patent/NO982850D0/no not_active Application Discontinuation
-
1999
- 1999-01-20 US US09/233,511 patent/US6255491B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
BR9612187A (pt) | 1999-07-13 |
IL124908A0 (en) | 1999-01-26 |
TW434236B (en) | 2001-05-16 |
IL143517A (en) | 2003-09-17 |
AU1468197A (en) | 1997-07-17 |
AR012567A1 (es) | 2000-11-08 |
AR004405A1 (es) | 1998-11-04 |
TR199801121T2 (xx) | 1998-08-21 |
EP1019393A1 (en) | 2000-07-19 |
NO982850L (no) | 1998-06-19 |
US5917043A (en) | 1999-06-29 |
HUP9902466A2 (hu) | 2000-05-28 |
NZ326574A (en) | 2000-01-28 |
IL143517A0 (en) | 2002-04-21 |
CN1209128A (zh) | 1999-02-24 |
HUP9902466A3 (en) | 2002-11-28 |
US6255491B1 (en) | 2001-07-03 |
NO982850D0 (no) | 1998-06-19 |
AR015579A1 (es) | 2001-05-16 |
IL124908A (en) | 2003-05-29 |
WO1997023479A1 (en) | 1997-07-03 |
US6100399A (en) | 2000-08-08 |
JP3245175B2 (ja) | 2002-01-07 |
AU704500B2 (en) | 1999-04-22 |
PL327311A1 (en) | 1998-12-07 |
CZ198598A3 (cs) | 1998-10-14 |
KR19990076625A (ko) | 1999-10-15 |
JP2000502683A (ja) | 2000-03-07 |
EP1019393A4 (en) | 2000-07-19 |
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