EP0974366B1
(en)
|
1997-03-28 |
2006-10-18 |
Eisai Co., Ltd. |
Oral pharmaceutical preparations decreased in bitterness by masking
|
US6635280B2
(en)
|
1997-06-06 |
2003-10-21 |
Depomed, Inc. |
Extending the duration of drug release within the stomach during the fed mode
|
CA2290624C
(en)
*
|
1997-06-06 |
2006-12-05 |
John W. Shell |
Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
|
FR2775188B1
(fr)
*
|
1998-02-23 |
2001-03-09 |
Lipha |
Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
|
US6099859A
(en)
|
1998-03-20 |
2000-08-08 |
Andrx Pharmaceuticals, Inc. |
Controlled release oral tablet having a unitary core
|
DE19823831A1
(de)
*
|
1998-05-28 |
1999-12-02 |
Probiodrug Ges Fuer Arzneim |
Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
|
US20040259895A1
(en)
*
|
1998-05-28 |
2004-12-23 |
Medical Research Institute |
Oral formulation of lipid soluble thiamine and lipoic acid
|
US6197340B1
(en)
*
|
1998-05-28 |
2001-03-06 |
Medical Research Institute |
Controlled release lipoic acid
|
US6117451A
(en)
*
|
1998-08-25 |
2000-09-12 |
Pharmalogix, Inc. |
Direct compression metformin hydrochloride tablets
|
WO2000012135A1
(fr)
*
|
1998-08-28 |
2000-03-09 |
Eisai Co., Ltd |
Compositions medicales presentant une amertume, etc., reduite
|
US6099862A
(en)
|
1998-08-31 |
2000-08-08 |
Andrx Corporation |
Oral dosage form for the controlled release of a biguanide and sulfonylurea
|
US6194466B1
(en)
*
|
1998-10-15 |
2001-02-27 |
Elizabeth Marie Cottingham |
Use of metformin to counteract weight gain associated with valproate and other psychotropic medications
|
US20040081697A1
(en)
*
|
1998-11-12 |
2004-04-29 |
Smithkline Beecham P.L.C. |
Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
|
US20040102486A1
(en)
*
|
1998-11-12 |
2004-05-27 |
Smithkline Beecham Corporation |
Novel method of treatment
|
US20030153607A1
(en)
*
|
1998-11-12 |
2003-08-14 |
Smithkline Beecham P.L.C. |
Novel composition and use
|
AU768994B2
(en)
*
|
1998-11-12 |
2004-01-15 |
Smithkline Beecham Plc |
Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
|
DZ2937A1
(fr)
*
|
1998-11-12 |
2004-03-15 |
Smithkline Beecham Plc |
Compositions nouvelles de sensibilidants à l'insuline.
|
AP1692A
(en)
*
|
1998-11-12 |
2006-12-12 |
Smithkline Beecham Plc |
Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent.
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
US6878749B2
(en)
*
|
1999-09-17 |
2005-04-12 |
Novartis Ag |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
|
CA2396782A1
(en)
|
2000-02-04 |
2001-08-09 |
Depomed, Inc. |
Shell-and-core dosage form approaching zero-order drug release
|
ATE437632T1
(de)
|
2000-03-01 |
2009-08-15 |
Eisai R&D Man Co Ltd |
Schnellzerfallende polyvinylhaltige tablette
|
US6676966B1
(en)
*
|
2000-05-09 |
2004-01-13 |
Intellipharmaceutics Corp. |
Extended release metformin hydrochloride formulations
|
US7858119B1
(en)
|
2000-05-09 |
2010-12-28 |
Amina Odidi |
Extended release pharmaceuticals
|
FR2811571B1
(fr)
|
2000-07-11 |
2002-10-11 |
Flamel Tech Sa |
Composition pharmaceutique orale, permettant la liberation controlee et l'absorption prolongee d'un principe actif
|
EP1322158B1
(en)
*
|
2000-10-02 |
2012-08-08 |
USV Ltd. |
Sustained release pharmaceutical compositions containing metformin and method of their production
|
US6451808B1
(en)
|
2000-10-17 |
2002-09-17 |
Depomed, Inc. |
Inhibition of emetic effect of metformin with 5-HT3 receptor antagonists
|
US6866866B1
(en)
*
|
2000-11-03 |
2005-03-15 |
Andrx Labs, Llc |
Controlled release metformin compositions
|
WO2002036100A1
(en)
*
|
2000-11-03 |
2002-05-10 |
Andrx Corporation |
Controlled release metformin compositions
|
US6790459B1
(en)
|
2000-11-03 |
2004-09-14 |
Andrx Labs, Llc |
Methods for treating diabetes via administration of controlled release metformin
|
US20060034922A1
(en)
*
|
2000-11-03 |
2006-02-16 |
Andrx Labs, Llc |
Controlled release metformin compositions
|
KR200249057Y1
(ko)
*
|
2001-03-22 |
2001-10-19 |
김진환 |
뚜껑, 받침대에 합체된 하수역류. 악취방지 장치
|
US6524618B1
(en)
|
2001-06-12 |
2003-02-25 |
Vijai Kumar |
Directly compressible extended-release matrix formulation for metformin hydrochloride
|
US20030021841A1
(en)
*
|
2001-07-02 |
2003-01-30 |
Matharu Amol Singh |
Pharmaceutical composition
|
IN192180B
(es)
*
|
2001-09-28 |
2004-03-06 |
Ranbaxy Lab |
|
WO2003026637A2
(en)
*
|
2001-09-28 |
2003-04-03 |
Sun Pharmaceutical Industries Limited |
Dosage form for treatment of diabetes mellitus
|
US8101209B2
(en)
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
US7612112B2
(en)
|
2001-10-25 |
2009-11-03 |
Depomed, Inc. |
Methods of treatment using a gastric retained gabapentin dosage
|
TWI312285B
(en)
|
2001-10-25 |
2009-07-21 |
Depomed Inc |
Methods of treatment using a gastric retained gabapentin dosage
|
CN1700910A
(zh)
*
|
2001-11-06 |
2005-11-23 |
兰贝克赛实验室有限公司 |
甲福明控释片剂
|
US20030118647A1
(en)
*
|
2001-12-04 |
2003-06-26 |
Pawan Seth |
Extended release tablet of metformin
|
WO2003061643A1
(es)
*
|
2002-01-25 |
2003-07-31 |
Laboratorios Silanes, S.A. De C.V. |
Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2
|
US20030187074A1
(en)
*
|
2002-03-04 |
2003-10-02 |
Javed Hussain |
Oral compositions for treatment of diabetes
|
CA2480826C
(fr)
|
2002-04-09 |
2012-02-07 |
Flamel Technologies |
Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
|
AU2003241537A1
(en)
*
|
2002-05-23 |
2003-12-12 |
Andrx Corporation |
Biguanide formulations
|
US20030224046A1
(en)
*
|
2002-06-03 |
2003-12-04 |
Vinay Rao |
Unit-dose combination composition for the simultaneous delivery of a short-acting and a long-acting oral hypoglycemic agent
|
WO2003105809A1
(en)
|
2002-06-17 |
2003-12-24 |
Themis Laboratories Private Limited |
Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
|
MY142204A
(en)
|
2002-07-25 |
2010-10-29 |
Pharmacia Corp |
Pramipexole once-daily dosage form
|
EP1549296A4
(en)
*
|
2002-08-02 |
2006-08-09 |
Penwest Pharmaceuticals Co |
METFORMIN FORMULATIONS WITH DELAYED RELEASE
|
US9060941B2
(en)
|
2002-09-20 |
2015-06-23 |
Actavis, Inc. |
Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
|
KR20120034211A
(ko)
|
2002-09-20 |
2012-04-10 |
안드렉스 랩스 엘엘씨 |
약제학적 정제
|
US8084058B2
(en)
*
|
2002-09-20 |
2011-12-27 |
Watson Pharmaceuticals, Inc. |
Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
|
US7959946B2
(en)
|
2002-09-20 |
2011-06-14 |
Watson Pharmaceuticals, Inc. |
Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
|
US7785627B2
(en)
|
2002-09-20 |
2010-08-31 |
Watson Pharmaceuticals, Inc. |
Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
|
US20040086566A1
(en)
*
|
2002-11-04 |
2004-05-06 |
Alpharma, Inc. |
Waxy matrix dosage forms
|
EP1646374A1
(en)
*
|
2003-06-16 |
2006-04-19 |
Ranbaxy Laboratories, Ltd. |
Extended-release tablets of metformin
|
US8802139B2
(en)
|
2003-06-26 |
2014-08-12 |
Intellipharmaceutics Corp. |
Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
|
EP1510208A1
(en)
|
2003-08-22 |
2005-03-02 |
Fournier Laboratories Ireland Limited |
Pharmaceutical composition comprising a combination of metformin and statin
|
US20050084531A1
(en)
*
|
2003-10-16 |
2005-04-21 |
Jatin Desai |
Tablet with aqueous-based sustained release coating
|
EP1591114A1
(en)
*
|
2004-03-12 |
2005-11-02 |
Fournier Laboratories Ireland Limited |
Use of metformin and orlistat for the treatment or prevention of obesity
|
KR100772980B1
(ko)
*
|
2004-04-01 |
2007-11-02 |
한미약품 주식회사 |
메트포르민의 경구투여용 서방성 제제
|
US8394409B2
(en)
|
2004-07-01 |
2013-03-12 |
Intellipharmaceutics Corp. |
Controlled extended drug release technology
|
CN101005830B
(zh)
*
|
2004-08-13 |
2010-09-29 |
贝林格尔·英格海姆国际有限公司 |
包含普拉克索或其可药用盐的延长释放片剂、其制备方法及用途
|
US10624858B2
(en)
|
2004-08-23 |
2020-04-21 |
Intellipharmaceutics Corp |
Controlled release composition using transition coating, and method of preparing same
|
EP1814528A2
(en)
*
|
2004-10-08 |
2007-08-08 |
Rubicon Research Private Limited |
Process for making a highly compressible controlled delivery compositions of metformin
|
US20060121108A1
(en)
*
|
2004-12-02 |
2006-06-08 |
Prasad C K |
System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
|
CA2607419C
(en)
|
2005-04-26 |
2014-06-17 |
Dainippon Sumitomo Pharma Co., Ltd. |
Granular preparation containing biguanide compound
|
KR100780553B1
(ko)
*
|
2005-08-18 |
2007-11-29 |
한올제약주식회사 |
메트포르민 서방정 및 그의 제조방법
|
MXPA05009633A
(es)
*
|
2005-09-08 |
2007-03-07 |
Silanes Sa De Cv Lab |
Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
|
US10064828B1
(en)
|
2005-12-23 |
2018-09-04 |
Intellipharmaceutics Corp. |
Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
|
US20090176882A1
(en)
|
2008-12-09 |
2009-07-09 |
Depomed, Inc. |
Gastric retentive gabapentin dosage forms and methods for using same
|
WO2007112581A1
(en)
|
2006-04-03 |
2007-10-11 |
Isa Odidi |
Controlled release delivery device comprising an organosol coat
|
US10960077B2
(en)
|
2006-05-12 |
2021-03-30 |
Intellipharmaceutics Corp. |
Abuse and alcohol resistant drug composition
|
KR100791844B1
(ko)
*
|
2006-06-30 |
2008-01-07 |
주식회사유한양행 |
메트포르민 또는 그의 염을 함유하는 서방성 제제 및 그의제조방법
|
KR20080009016A
(ko)
*
|
2006-07-21 |
2008-01-24 |
주식회사 한독약품 |
위 체류형 펠렛 및 이의 제조방법
|
US8778398B2
(en)
|
2008-11-04 |
2014-07-15 |
Jazz Pharmaceuticals, Inc. |
Immediate release formulations and dosage forms of gamma-hydroxybutyrate
|
RU2532330C2
(ru)
|
2009-04-16 |
2014-11-10 |
Тайсо Фармасьютикал Ко., Лтд. |
Фармацевтические композиции
|
SI2498759T1
(sl)
|
2009-11-13 |
2018-12-31 |
Astrazeneca Ab |
Formulacije tablet s takojšnjim sproščanjem
|
CA2987757C
(en)
*
|
2009-11-13 |
2021-04-13 |
Astrazeneca Uk Limited |
Bilayer tablet formulations
|
US20120076865A1
(en)
*
|
2010-03-24 |
2012-03-29 |
Jazz Pharmaceuticals, Inc. |
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
|
US8581001B2
(en)
|
2010-04-16 |
2013-11-12 |
Codman & Shurtleff |
Metformin-cysteine prodrug
|
RU2465896C2
(ru)
*
|
2011-01-20 |
2012-11-10 |
Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") |
Фармацевтическая противодиабетическая композиция пролонгированного действия
|
MX2012014070A
(es)
*
|
2012-12-03 |
2014-06-23 |
Landsteiner Scient S A De C V |
Composiciones metformina-orlistat.
|
US10258583B2
(en)
|
2014-05-01 |
2019-04-16 |
Sun Pharmaceutical Industries Limited |
Extended release liquid compositions of guanfacine
|
US20180104197A9
(en)
|
2014-05-01 |
2018-04-19 |
Sun Pharmaceutical Industries Limited |
Extended release liquid compositions of metformin
|
US9962336B2
(en)
|
2014-05-01 |
2018-05-08 |
Sun Pharmaceutical Industries Limited |
Extended release suspension compositions
|
RU2016147008A
(ru)
*
|
2014-05-01 |
2018-06-04 |
Сан Фармасьютикал Индастриз Лимитед |
Жидкие композиции метформина с пролонгированным высвобождением
|
AU2015254875A1
(en)
*
|
2014-05-01 |
2016-11-17 |
Sun Pharmaceutical Industries Limited |
Extended release suspension compositions
|
WO2015183794A1
(en)
|
2014-05-27 |
2015-12-03 |
City Of Hope |
Tgr5 agonist complexes for treating diabetes and cancer
|
BR112017001968A2
(pt)
|
2014-07-30 |
2017-11-21 |
Sun Pharmaceutical Ind Ltd |
embalagem de duas câmaras para uma composição farmacêutica líquida oral de múltiplas doses
|
US10398662B1
(en)
|
2015-02-18 |
2019-09-03 |
Jazz Pharma Ireland Limited |
GHB formulation and method for its manufacture
|
US10238803B2
(en)
|
2016-05-02 |
2019-03-26 |
Sun Pharmaceutical Industries Limited |
Drug delivery device for pharmaceutical compositions
|
UY37341A
(es)
|
2016-07-22 |
2017-11-30 |
Flamel Ireland Ltd |
Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
|
US11602512B1
(en)
|
2016-07-22 |
2023-03-14 |
Flamel Ireland Limited |
Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
|
US11504347B1
(en)
|
2016-07-22 |
2022-11-22 |
Flamel Ireland Limited |
Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
|
US11986451B1
(en)
|
2016-07-22 |
2024-05-21 |
Flamel Ireland Limited |
Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
|
US11602513B1
(en)
|
2016-07-22 |
2023-03-14 |
Flamel Ireland Limited |
Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
|
US20190365785A1
(en)
*
|
2017-02-22 |
2019-12-05 |
Children's Hospital Medical Center |
Inhibition of unfolded protein response for suppressing or preventing allergic reaction to food
|
US20180263936A1
(en)
|
2017-03-17 |
2018-09-20 |
Jazz Pharmaceuticals Ireland Limited |
Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
|
CN108451923A
(zh)
*
|
2018-05-31 |
2018-08-28 |
常州兰陵制药有限公司 |
盐酸二甲双胍速释胶囊及其制备方法
|
JP7472116B2
(ja)
|
2018-11-19 |
2024-04-22 |
ジャズ ファーマシューティカルズ アイルランド リミテッド |
耐アルコール性製剤
|
JP7553453B2
(ja)
|
2019-03-01 |
2024-09-18 |
フラメル アイルランド リミテッド |
食事摂取状態における改善された薬物動態を有するガンマ-ヒドロキシ酪酸塩組成物
|
US11779557B1
(en)
|
2022-02-07 |
2023-10-10 |
Flamel Ireland Limited |
Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
|
US11583510B1
(en)
|
2022-02-07 |
2023-02-21 |
Flamel Ireland Limited |
Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
|