ZA952410B - Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals - Google Patents

Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals

Info

Publication number
ZA952410B
ZA952410B ZA952410A ZA952410A ZA952410B ZA 952410 B ZA952410 B ZA 952410B ZA 952410 A ZA952410 A ZA 952410A ZA 952410 A ZA952410 A ZA 952410A ZA 952410 B ZA952410 B ZA 952410B
Authority
ZA
South Africa
Prior art keywords
carboxamioesters
pharmaceuticals
preparation
substituted heterocyclic
heterocyclic
Prior art date
Application number
ZA952410A
Other languages
English (en)
Inventor
Klaus Weidmann
Karl-Heinz Baringhaus
Georg Tschank
Martin Bickel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA952410B publication Critical patent/ZA952410B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
ZA952410A 1994-03-25 1995-03-24 Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals ZA952410B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410453A DE4410453A1 (de) 1994-03-25 1994-03-25 Substituierte heterocyclische Carbonsäureamidester, ihre Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ZA952410B true ZA952410B (en) 1995-12-01

Family

ID=6513880

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA952410A ZA952410B (en) 1994-03-25 1995-03-24 Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals

Country Status (12)

Country Link
EP (1) EP0673930A1 (xx)
JP (1) JPH07278111A (xx)
KR (1) KR950032127A (xx)
AU (1) AU1504495A (xx)
CA (1) CA2145473A1 (xx)
CZ (1) CZ73595A3 (xx)
DE (1) DE4410453A1 (xx)
FI (1) FI951388A (xx)
HU (1) HUT72596A (xx)
NO (1) NO951147L (xx)
PL (1) PL307846A1 (xx)
ZA (1) ZA952410B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0206711D0 (en) * 2002-03-21 2002-05-01 Isis Innovation HIF Inhibitor
US8558002B2 (en) 2006-11-16 2013-10-15 Allergan, Inc. Sulfoximines as kinase inhibitors
CA2669704A1 (en) * 2006-11-16 2008-05-22 Allergan, Inc. Sulfoximines as kinase inhibitors
CN112250627B (zh) 2014-10-06 2024-02-02 弗特克斯药品有限公司 囊性纤维化跨膜转导调节因子调节剂
WO2017173274A1 (en) 2016-03-31 2017-10-05 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
RS62670B1 (sr) 2016-09-30 2021-12-31 Vertex Pharma Modulator transmembranskog regulatora provodnosti cistične fibroze, farmaceutske kompozicije, metode lečenja i proces izrade modulatora
MX2019006637A (es) 2016-12-09 2019-08-21 Vertex Pharma Modulador del regulador de conductancia transmembrana de fibrosis quistica composiciones farmaceuticas metodos de tratamiento y proceso para producir el modulador.
AU2018279646B2 (en) 2017-06-08 2023-04-06 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
MA49631A (fr) 2017-07-17 2020-05-27 Vertex Pharma Méthodes de traitement de la fibrose kystique
CA3071278A1 (en) 2017-08-02 2019-02-07 Vertex Pharmaceuticals Incorporated Processes for preparing pyrrolidine compounds
CA3078893A1 (en) 2017-10-19 2019-04-25 Vertex Pharmaceuticals Incorporated Crystalline forms and compositions of cftr modulators
MX2020005753A (es) 2017-12-08 2020-08-20 Vertex Pharma Procesos para producir moduladores de regulador de conductancia transmembranal de fibrosis quistica.
TWI810243B (zh) 2018-02-05 2023-08-01 美商維泰克斯製藥公司 用於治療囊腫纖化症之醫藥組合物
WO2019200246A1 (en) 2018-04-13 2019-10-17 Alexander Russell Abela Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
JPH07278111A (ja) 1995-10-24
CZ73595A3 (en) 1995-11-15
FI951388A (fi) 1995-09-26
NO951147D0 (no) 1995-03-24
CA2145473A1 (en) 1995-09-26
FI951388A0 (fi) 1995-03-23
AU1504495A (en) 1995-10-05
DE4410453A1 (de) 1995-09-28
NO951147L (no) 1995-09-26
KR950032127A (ko) 1995-12-20
HUT72596A (en) 1996-05-28
EP0673930A1 (de) 1995-09-27
PL307846A1 (en) 1995-10-02

Similar Documents

Publication Publication Date Title
IL126638A0 (en) Substituted isoquinoline-3-carboxamides their preparation and their use as pharmaceuticals
HU9503045D0 (en) Heterocyclic compounds and their preparation and use
AU3577995A (en) Urea derivatives and their use as acat-inhibitors
IL116325A0 (en) Substituted 1h-imidazoles their preparation and use
KR19987002466A (en) Pyrazol-4-yl-benzoyl derivatives and their use as herbicides
IL114795A0 (en) N-benzylindole- and benmzopyrazole derivatives their preparation and use
EP0788489A4 (en) HETEROCYCLIC COMPOUNDS AND THEIR USE
AU1106195A (en) Heterocyclic compounds, their preparation and use
IL116139A0 (en) Pyrrole derivatives their preparation and use
IL116525A0 (en) Piperazinedione derivatives their preparation and use
ZA952410B (en) Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals
GR3029434T3 (en) Substituted biphenyloxazolines and their use as fungicides
ZA941926B (en) Heterocyclic compounds their preparation and use
PL315970A1 (en) Substituted triazolynones and their application as herbicides
HU9602749D0 (en) Substituted sulphonylaminocarbonyltriazolinones and their use as herbicides
HUP0001781A3 (en) Substituted pyrazolyl-pyrazole derivatives and their use as herbicides
IL114490A0 (en) Heterocyclic compounds their preparation and their use
AU3650695A (en) New heterocyclic substituted imidazoloquinoxalinones, their preparation and their use
AU2152497A (en) Heterocyclic compounds and their preparation and use
HK1044772A1 (zh) 雜環n-丙酮基苯甲酰胺以及它們作為殺菌劑的使用
ZA952407B (en) Substituted heterocyclic carboxamides their preparation and their use as pharmaceuticals
IL114333A0 (en) Pyrimidinyl- and triazinyl-oxy-and-thio-3-haloalkyl-propionic acid derivatives their preparation and use
HU9500177D0 (en) 3-aryluracil derivatives and their use as herbicides
ZA948580B (en) Substituted heterocyclic carboxamides their preparation and their use as pharmaceuticals
ZA9410340B (en) Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals