ZA9511035B - 8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application - Google Patents

8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application

Info

Publication number
ZA9511035B
ZA9511035B ZA9511035A ZA9511035A ZA9511035B ZA 9511035 B ZA9511035 B ZA 9511035B ZA 9511035 A ZA9511035 A ZA 9511035A ZA 9511035 A ZA9511035 A ZA 9511035A ZA 9511035 B ZA9511035 B ZA 9511035B
Authority
ZA
South Africa
Prior art keywords
quinolizine
dibenzo
dihydro
oxo
preparation
Prior art date
Application number
ZA9511035A
Other languages
English (en)
Inventor
Benoit Marabout
Mireille Sevrin
Jacques Froissant
Emmanuelle Dachary
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA9511035B publication Critical patent/ZA9511035B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Addiction (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9511035A 1994-12-29 1995-12-28 8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application ZA9511035B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9415836A FR2728902B1 (fr) 1994-12-29 1994-12-29 Derives d'acide 8-oxo-5,8-dihydro-6h-dibenzo(a,g)quinolizine-13-propanoique, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ZA9511035B true ZA9511035B (en) 1996-07-01

Family

ID=9470389

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9511035A ZA9511035B (en) 1994-12-29 1995-12-28 8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives their preparation and their therapeutic application

Country Status (26)

Country Link
US (1) US5614517A (no)
EP (1) EP0719776B1 (no)
JP (1) JPH08239383A (no)
KR (1) KR960022518A (no)
CN (1) CN1058009C (no)
AR (1) AR002015A1 (no)
AT (1) ATE172973T1 (no)
AU (1) AU697988B2 (no)
BR (1) BR9506105A (no)
CA (1) CA2166233A1 (no)
CO (1) CO4700297A1 (no)
CZ (1) CZ348895A3 (no)
DE (1) DE69505781T2 (no)
DK (1) DK0719776T3 (no)
ES (1) ES2126232T3 (no)
FI (1) FI956299A (no)
FR (1) FR2728902B1 (no)
HU (1) HU215393B (no)
IL (1) IL116596A (no)
NO (1) NO305084B1 (no)
NZ (1) NZ280766A (no)
PL (1) PL181811B1 (no)
RU (1) RU2155764C2 (no)
SK (1) SK280546B6 (no)
TW (1) TW385311B (no)
ZA (1) ZA9511035B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2806723B1 (fr) * 2000-03-23 2002-05-10 Sanofi Synthelabo DERIVES D'ACIDE 8-OXO-5,8-DIHYDRO-6H-DIBENZO [a,g] QUINOLIZINE-13-PROPANOIQUE , LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
CN104127414B (zh) * 2013-05-03 2018-04-13 中国科学院上海药物研究所 一种六氢二苯并[a,g]喹嗪类化合物的药物用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013616A (en) * 1971-11-22 1977-03-22 Wallace Richard A Mixed polymeric structural material and method

Also Published As

Publication number Publication date
EP0719776A1 (fr) 1996-07-03
CZ348895A3 (en) 1996-07-17
HU9503846D0 (en) 1996-02-28
AR002015A1 (es) 1998-01-07
HUT74186A (en) 1996-11-28
SK280546B6 (sk) 2000-03-13
CN1058009C (zh) 2000-11-01
JPH08239383A (ja) 1996-09-17
TW385311B (en) 2000-03-21
EP0719776B1 (fr) 1998-11-04
NO955325D0 (no) 1995-12-28
CO4700297A1 (es) 1998-12-29
FR2728902A1 (fr) 1996-07-05
NZ280766A (en) 1996-09-25
US5614517A (en) 1997-03-25
AU697988B2 (en) 1998-10-22
NO955325L (no) 1996-07-01
IL116596A (en) 1998-10-30
FI956299A0 (fi) 1995-12-28
CA2166233A1 (en) 1996-06-30
PL181811B1 (pl) 2001-09-28
DE69505781D1 (de) 1998-12-10
FI956299A (fi) 1996-06-30
PL312080A1 (en) 1996-07-08
FR2728902B1 (fr) 1997-01-31
HU215393B (hu) 1998-12-28
BR9506105A (pt) 1997-12-23
AU4070895A (en) 1996-07-04
IL116596A0 (en) 1996-03-31
DK0719776T3 (da) 1999-07-19
ATE172973T1 (de) 1998-11-15
NO305084B1 (no) 1999-03-29
SK165895A3 (en) 1996-07-03
ES2126232T3 (es) 1999-03-16
DE69505781T2 (de) 1999-06-17
CN1131154A (zh) 1996-09-18
RU2155764C2 (ru) 2000-09-10
KR960022518A (ko) 1996-07-18

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