ZA942037B - Process for the preparation of a liposome dispersion under elevated pressure conditions - Google Patents

Process for the preparation of a liposome dispersion under elevated pressure conditions

Info

Publication number
ZA942037B
ZA942037B ZA942037A ZA942037A ZA942037B ZA 942037 B ZA942037 B ZA 942037B ZA 942037 A ZA942037 A ZA 942037A ZA 942037 A ZA942037 A ZA 942037A ZA 942037 B ZA942037 B ZA 942037B
Authority
ZA
South Africa
Prior art keywords
substances
preparation
mixtures
soluble
pressure conditions
Prior art date
Application number
ZA942037A
Other languages
English (en)
Inventor
Lene Frederiksen
Klaus Anton
Peter Van Hoogevest
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA942037B publication Critical patent/ZA942037B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA942037A 1993-03-24 1994-03-23 Process for the preparation of a liposome dispersion under elevated pressure conditions ZA942037B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH89193 1993-03-24

Publications (1)

Publication Number Publication Date
ZA942037B true ZA942037B (en) 1994-09-26

Family

ID=4197591

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA942037A ZA942037B (en) 1993-03-24 1994-03-23 Process for the preparation of a liposome dispersion under elevated pressure conditions

Country Status (15)

Country Link
US (1) US5700482A (sv)
EP (1) EP0616801B1 (sv)
JP (1) JPH06315624A (sv)
KR (1) KR940021050A (sv)
AT (1) ATE166573T1 (sv)
AU (1) AU676257B2 (sv)
CA (1) CA2119610C (sv)
DE (1) DE59406065D1 (sv)
FI (1) FI111687B (sv)
HU (1) HU219352B (sv)
IL (1) IL109070A (sv)
NO (1) NO306846B1 (sv)
NZ (1) NZ260154A (sv)
PH (1) PH30470A (sv)
ZA (1) ZA942037B (sv)

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DE4445341A1 (de) * 1994-12-19 1996-06-20 Basf Ag Verfahren und Vorrichtung zur Herstellung wirkstoffhaltiger Dispersionen
US6375930B2 (en) 1996-06-04 2002-04-23 Board Of Regents, The University Of Texas System Membrane incorporation of texaphyrins
DE19639811A1 (de) * 1996-09-27 1998-04-02 Artur Herzog Dr Mesmer Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
DE19711393C1 (de) * 1997-03-19 1998-08-13 Fraunhofer Ges Forschung Verfahren zum Mikroverkapseln von Partikeln
JP4467789B2 (ja) 1997-09-18 2010-05-26 パシラ ファーマシューティカルズ インコーポレーテッド 持続放出性リポソーム麻酔組成物
IL135989A0 (en) * 1997-11-14 2001-05-20 Skyepharma Inc Processes for the production of multivesicular liposomes
AU2868099A (en) * 1998-02-13 1999-08-30 Selective Genetics, Inc. Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby
US6706280B2 (en) * 1998-08-19 2004-03-16 Bracco Research S.A. Carboxylated phosphatidic acid esters
US6855296B1 (en) 1998-11-13 2005-02-15 Optime Therapeutics, Inc. Method and apparatus for liposome production
IL143104A (en) * 1998-11-13 2005-09-25 Optime Therapeutics Inc Method and apparatus for liposome production
FR2803539B1 (fr) * 2000-01-07 2002-07-12 Separex Sa Procede de captage et d'encapsulation de fines particules
WO2002032564A1 (fr) * 2000-10-13 2002-04-25 National Institute Of Advanced Industrial Science And Technology Procede et appareil de production de liposomes
CA2437578A1 (en) * 2001-02-13 2002-08-22 Rivka Cohen Carotenoid-loaded liposomes
WO2002089851A1 (fr) * 2001-03-06 2002-11-14 Separex (Societe Anonyme) Procede de fabrication de complexes hote-client
FR2830760B1 (fr) * 2001-10-12 2004-06-04 Pf Medicament Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique
FR2854079B1 (fr) * 2003-04-25 2007-11-30 Pf Medicament Procede de preparation de complexes moleculaires
JP4595319B2 (ja) * 2003-12-03 2010-12-08 コニカミノルタエムジー株式会社 リポソーム用脂質、リポソームおよびそれらの製造方法
DK1718283T3 (da) 2004-01-22 2013-04-22 Univ Miami Topisk co-enzyme Q10 formuleringer og fremgangsmåder for anvendelse.
JP4649841B2 (ja) * 2004-02-18 2011-03-16 コニカミノルタエムジー株式会社 リポソーム含有製剤の製造方法、およびリポソーム含有製剤
JPWO2006009022A1 (ja) * 2004-07-21 2008-05-01 コニカミノルタエムジー株式会社 リポソーム含有ｘ線造影剤およびその製造方法
EP1776948B1 (en) * 2004-08-11 2015-12-09 Konica Minolta Medical & Graphic, Inc. Method of producing liposome-containing preparation
JP2006056807A (ja) * 2004-08-18 2006-03-02 Konica Minolta Medical & Graphic Inc 光線力学療法製剤
JP4715133B2 (ja) * 2004-08-26 2011-07-06 コニカミノルタエムジー株式会社 抗腫瘍リポソーム製剤およびその製造方法
JP2006069929A (ja) * 2004-08-31 2006-03-16 Konica Minolta Medical & Graphic Inc 真菌症治療製剤およびその製造方法
US20080045575A1 (en) * 2004-12-29 2008-02-21 Van Dyke Thomas E Delivery of H2 Antagonists
WO2006113573A1 (en) * 2005-04-15 2006-10-26 Advanced Technology Materials, Inc. Apparatus and method for supercritical fluid removal or deposition processes
JP2006298838A (ja) * 2005-04-21 2006-11-02 Konica Minolta Medical & Graphic Inc リポソーム含有ｘ線造影剤
FR2889665B1 (fr) * 2005-08-12 2007-11-09 Pic Solution Soc Par Actions S Procede et installation pour la regulation du taux de modificateur dans une chromatographie ou extraction supercritique avec recyclage
JP2007217369A (ja) * 2006-02-17 2007-08-30 Trendy:Kk 除毛剤、除毛剤の製造方法、および除毛方法
CA2823407C (en) 2007-03-22 2016-10-18 Berg Pharma Llc Topical formulations having enhanced bioavailability
WO2009126764A1 (en) 2008-04-11 2009-10-15 Cytotech Labs, Llc Methods and use of inducing apoptosis in cancer cells
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
JP2012526828A (ja) 2009-05-11 2012-11-01 バーグ バイオシステムズ，エルエルシー エピメタボリックシフター、多次元細胞内分子、または環境影響因子を使用する代謝性障害の治療方法
ES2664793T3 (es) * 2010-03-12 2018-04-23 Berg Llc Formulaciones intravenosas de coenzima Q10 (CoQ10) y métodos de uso de las mismas
ES2762451T3 (es) 2011-04-04 2020-05-25 Berg Llc Tratamiento de tumores del sistema nervioso central con coenzima Q10
JP5932993B2 (ja) 2011-06-17 2016-06-08 バーグ エルエルシー 吸入可能な医薬組成物
US20130177629A1 (en) 2011-12-22 2013-07-11 Nuvo Research Gmbh Liposomal compositions
EA032775B1 (ru) 2013-04-08 2019-07-31 Берг Ллк Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10
JP6595478B2 (ja) 2013-09-04 2019-10-23 バーグ エルエルシー コエンザイムｑ１０の連続注入によるがんの治療方法
JP6316182B2 (ja) * 2014-12-19 2018-04-25 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
WO2019088193A1 (ja) 2017-11-01 2019-05-09 国立大学法人大阪大学 所望の粒径を有する脂質粒子を製造するための方法および装置の開発
JP7460534B2 (ja) 2018-03-30 2024-04-02 インスメッド インコーポレイテッド リポソーム医薬品の連続製造方法
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
CN114469734B (zh) * 2021-10-13 2023-08-04 成都科建生物医药有限公司 一种蒽环类药物脂质体的制备装置与制备方法
CN114469733B (zh) * 2021-10-13 2023-06-09 成都科建生物医药有限公司 一种阿霉素脂质体的制备装置与制备方法

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GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
WO1988001864A1 (en) * 1986-09-18 1988-03-24 Liposome Technology, Inc. High-concentration liposome processing method
US4752425A (en) * 1986-09-18 1988-06-21 Liposome Technology, Inc. High-encapsulation liposome processing method
DE3812816A1 (de) * 1988-04-16 1989-11-02 Lawaczeck Ruediger Dipl Phys P Verfahren zur solubilisierung von liposomen und/oder biologischer membranen sowie deren verwendung
US5123414A (en) * 1989-12-22 1992-06-23 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5270053A (en) * 1990-04-03 1993-12-14 Ciba-Geigy Corp. Parenterally administerable liposome formulation comprising synthetic lipid

Also Published As

Publication number Publication date
KR940021050A (ko) 1994-10-17
NZ260154A (en) 1995-08-28
PH30470A (en) 1997-05-28
EP0616801B1 (de) 1998-05-27
ATE166573T1 (de) 1998-06-15
CA2119610A1 (en) 1994-09-25
CA2119610C (en) 2003-07-08
NO306846B1 (no) 2000-01-03
HU9400827D0 (en) 1994-06-28
AU5788894A (en) 1994-09-29
DE59406065D1 (de) 1998-07-02
HUT67384A (en) 1995-04-28
HU219352B (en) 2001-03-28
JPH06315624A (ja) 1994-11-15
EP0616801A1 (de) 1994-09-28
NO941054D0 (no) 1994-03-23
US5700482A (en) 1997-12-23
FI111687B (sv) 2003-09-15
IL109070A (en) 1998-04-05
IL109070A0 (en) 1994-06-24
NO941054L (no) 1994-09-26
FI941317A (sv) 1994-09-25
AU676257B2 (en) 1997-03-06
FI941317A0 (sv) 1994-03-21

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