ZA942037B - Process for the preparation of a liposome dispersion under elevated pressure conditions - Google Patents

Process for the preparation of a liposome dispersion under elevated pressure conditions

Info

Publication number
ZA942037B
ZA942037B ZA942037A ZA942037A ZA942037B ZA 942037 B ZA942037 B ZA 942037B ZA 942037 A ZA942037 A ZA 942037A ZA 942037 A ZA942037 A ZA 942037A ZA 942037 B ZA942037 B ZA 942037B
Authority
ZA
South Africa
Prior art keywords
substances
preparation
mixtures
soluble
pressure conditions
Prior art date
Application number
ZA942037A
Other languages
English (en)
Inventor
Lene Frederiksen
Klaus Anton
Peter Van Hoogevest
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA942037B publication Critical patent/ZA942037B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA942037A 1993-03-24 1994-03-23 Process for the preparation of a liposome dispersion under elevated pressure conditions ZA942037B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH89193 1993-03-24

Publications (1)

Publication Number Publication Date
ZA942037B true ZA942037B (en) 1994-09-26

Family

ID=4197591

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA942037A ZA942037B (en) 1993-03-24 1994-03-23 Process for the preparation of a liposome dispersion under elevated pressure conditions

Country Status (15)

Country Link
US (1) US5700482A (xx)
EP (1) EP0616801B1 (xx)
JP (1) JPH06315624A (xx)
KR (1) KR940021050A (xx)
AT (1) ATE166573T1 (xx)
AU (1) AU676257B2 (xx)
CA (1) CA2119610C (xx)
DE (1) DE59406065D1 (xx)
FI (1) FI111687B (xx)
HU (1) HU219352B (xx)
IL (1) IL109070A (xx)
NO (1) NO306846B1 (xx)
NZ (1) NZ260154A (xx)
PH (1) PH30470A (xx)
ZA (1) ZA942037B (xx)

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DE4445341A1 (de) * 1994-12-19 1996-06-20 Basf Ag Verfahren und Vorrichtung zur Herstellung wirkstoffhaltiger Dispersionen
US6375930B2 (en) 1996-06-04 2002-04-23 Board Of Regents, The University Of Texas System Membrane incorporation of texaphyrins
DE19639811A1 (de) * 1996-09-27 1998-04-02 Artur Herzog Dr Mesmer Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
DE19711393C1 (de) * 1997-03-19 1998-08-13 Fraunhofer Ges Forschung Verfahren zum Mikroverkapseln von Partikeln
CA2304096C (en) 1997-09-18 2003-09-09 Skyepharma Inc. Sustained-release liposomal anesthetic compositions
NZ504188A (en) 1997-11-14 2001-10-26 Skyepharma Inc Emulsification process for preparing multivesicular liposomes
US6537813B1 (en) * 1998-02-13 2003-03-25 Selective Genetics, Inc. Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby
US6706280B2 (en) * 1998-08-19 2004-03-16 Bracco Research S.A. Carboxylated phosphatidic acid esters
US6855296B1 (en) 1998-11-13 2005-02-15 Optime Therapeutics, Inc. Method and apparatus for liposome production
CA2350430C (en) * 1998-11-13 2008-06-03 Optime Therapeutics, Inc. Method and apparatus for liposome production
FR2803539B1 (fr) * 2000-01-07 2002-07-12 Separex Sa Procede de captage et d'encapsulation de fines particules
EP1334765B1 (en) * 2000-10-13 2010-06-30 National Institute of Advanced Industrial Science and Technology Process for producing liposome
US7048943B2 (en) * 2001-02-13 2006-05-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem Carotenoid-loaded liposomes
WO2002089851A1 (fr) * 2001-03-06 2002-11-14 Separex (Societe Anonyme) Procede de fabrication de complexes hote-client
FR2830760B1 (fr) * 2001-10-12 2004-06-04 Pf Medicament Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique
FR2854079B1 (fr) * 2003-04-25 2007-11-30 Pf Medicament Procede de preparation de complexes moleculaires
JP4595319B2 (ja) * 2003-12-03 2010-12-08 コニカミノルタエムジー株式会社 リポソーム用脂質、リポソームおよびそれらの製造方法
ES2410587T3 (es) 2004-01-22 2013-07-02 University Of Miami Formulaciones tópicas de coenzima Q10 y métodos de uso
JP4649841B2 (ja) * 2004-02-18 2011-03-16 コニカミノルタエムジー株式会社 リポソーム含有製剤の製造方法、およびリポソーム含有製剤
JPWO2006009022A1 (ja) * 2004-07-21 2008-05-01 コニカミノルタエムジー株式会社 リポソーム含有x線造影剤およびその製造方法
EP1776948B1 (en) 2004-08-11 2015-12-09 Konica Minolta Medical & Graphic, Inc. Method of producing liposome-containing preparation
JP2006056807A (ja) * 2004-08-18 2006-03-02 Konica Minolta Medical & Graphic Inc 光線力学療法製剤
JP4715133B2 (ja) * 2004-08-26 2011-07-06 コニカミノルタエムジー株式会社 抗腫瘍リポソーム製剤およびその製造方法
JP2006069929A (ja) * 2004-08-31 2006-03-16 Konica Minolta Medical & Graphic Inc 真菌症治療製剤およびその製造方法
WO2006071659A1 (en) * 2004-12-29 2006-07-06 Trustees Of Boston University Delivery of h2 antagonists
TW200726858A (en) * 2005-04-15 2007-07-16 Advanced Tech Materials Apparatus and method for supercritical fluid removal or deposition processes
JP2006298838A (ja) * 2005-04-21 2006-11-02 Konica Minolta Medical & Graphic Inc リポソーム含有x線造影剤
FR2889665B1 (fr) * 2005-08-12 2007-11-09 Pic Solution Soc Par Actions S Procede et installation pour la regulation du taux de modificateur dans une chromatographie ou extraction supercritique avec recyclage
JP2007217369A (ja) * 2006-02-17 2007-08-30 Trendy:Kk 除毛剤、除毛剤の製造方法、および除毛方法
EP2136787B1 (en) 2007-03-22 2019-08-21 Berg LLC Topical formulations having enhanced bioavailability
CN103462896A (zh) 2008-04-11 2013-12-25 细胞研究有限公司 诱导癌细胞凋亡的方法和应用
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
WO2010132479A2 (en) 2009-05-11 2010-11-18 Cytotech Labs, Llc Methods for the diagnosis of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
SG10202010355PA (en) * 2010-03-12 2020-11-27 Berg Llc Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
CA2832324C (en) 2011-04-04 2022-03-15 Berg Llc Methods of treating central nervous system tumors
EA201490047A1 (ru) 2011-06-17 2014-08-29 Берг Ллк Ингаляционные фармацевтические композиции
CA2857604A1 (en) 2011-12-22 2013-06-27 Nuvo Research Gmbh Liposomal chlorite or chlorate compositions
KR102279451B1 (ko) 2013-04-08 2021-07-19 버그 엘엘씨 코엔자임 q10 병용 요법을 이용한 암 치료
KR102370843B1 (ko) 2013-09-04 2022-03-04 버그 엘엘씨 코엔자임 q10의 연속주입에 의한 암치료 방법
JP6316182B2 (ja) * 2014-12-19 2018-04-25 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
WO2019088193A1 (ja) * 2017-11-01 2019-05-09 国立大学法人大阪大学 所望の粒径を有する脂質粒子を製造するための方法および装置の開発
EP3773505A4 (en) 2018-03-30 2021-12-22 Insmed Incorporated PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
CN114469733B (zh) * 2021-10-13 2023-06-09 成都科建生物医药有限公司 一种阿霉素脂质体的制备装置与制备方法
CN114469734B (zh) * 2021-10-13 2023-08-04 成都科建生物医药有限公司 一种蒽环类药物脂质体的制备装置与制备方法

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GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
US4752425A (en) * 1986-09-18 1988-06-21 Liposome Technology, Inc. High-encapsulation liposome processing method
EP0285638A4 (en) * 1986-09-18 1989-06-14 Liposome Technology Inc METHOD FOR PRODUCING A HIGH DENSITY LIPOSOME.
DE3812816A1 (de) * 1988-04-16 1989-11-02 Lawaczeck Ruediger Dipl Phys P Verfahren zur solubilisierung von liposomen und/oder biologischer membranen sowie deren verwendung
US5123414A (en) * 1989-12-22 1992-06-23 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5270053A (en) * 1990-04-03 1993-12-14 Ciba-Geigy Corp. Parenterally administerable liposome formulation comprising synthetic lipid

Also Published As

Publication number Publication date
JPH06315624A (ja) 1994-11-15
EP0616801B1 (de) 1998-05-27
DE59406065D1 (de) 1998-07-02
US5700482A (en) 1997-12-23
HU9400827D0 (en) 1994-06-28
IL109070A0 (en) 1994-06-24
NZ260154A (en) 1995-08-28
FI941317A0 (fi) 1994-03-21
AU676257B2 (en) 1997-03-06
NO306846B1 (no) 2000-01-03
NO941054L (no) 1994-09-26
NO941054D0 (no) 1994-03-23
CA2119610A1 (en) 1994-09-25
PH30470A (en) 1997-05-28
AU5788894A (en) 1994-09-29
ATE166573T1 (de) 1998-06-15
HUT67384A (en) 1995-04-28
HU219352B (en) 2001-03-28
FI941317A (fi) 1994-09-25
IL109070A (en) 1998-04-05
FI111687B (fi) 2003-09-15
EP0616801A1 (de) 1994-09-28
CA2119610C (en) 2003-07-08
KR940021050A (ko) 1994-10-17

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