ZA941926B - Heterocyclic compounds their preparation and use - Google Patents

Heterocyclic compounds their preparation and use

Info

Publication number
ZA941926B
ZA941926B ZA941926A ZA941926A ZA941926B ZA 941926 B ZA941926 B ZA 941926B ZA 941926 A ZA941926 A ZA 941926A ZA 941926 A ZA941926 A ZA 941926A ZA 941926 B ZA941926 B ZA 941926B
Authority
ZA
South Africa
Prior art keywords
preparation
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
ZA941926A
Other languages
English (en)
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Lone Jeppesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA941926B publication Critical patent/ZA941926B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA941926A 1993-03-19 1994-03-18 Heterocyclic compounds their preparation and use ZA941926B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93310A DK31093D0 (ko) 1993-03-19 1993-03-19

Publications (1)

Publication Number Publication Date
ZA941926B true ZA941926B (en) 1995-09-18

Family

ID=8092112

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA941926A ZA941926B (en) 1993-03-19 1994-03-18 Heterocyclic compounds their preparation and use

Country Status (16)

Country Link
US (1) US5559106A (ko)
EP (1) EP0691969A1 (ko)
JP (1) JPH08507536A (ko)
KR (1) KR100313051B1 (ko)
CN (1) CN1041930C (ko)
AU (1) AU685783B2 (ko)
CA (1) CA2158545A1 (ko)
DK (1) DK31093D0 (ko)
FI (1) FI954386A0 (ko)
HU (1) HUT73419A (ko)
IL (1) IL108800A (ko)
NO (1) NO305286B1 (ko)
NZ (1) NZ262365A (ko)
TW (1) TW304195B (ko)
WO (1) WO1994021639A1 (ko)
ZA (1) ZA941926B (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
ATE190616T1 (de) * 1994-09-16 2000-04-15 Novo Nordisk As (1,2,4)triazolo(4,3-a)chinoxylinonderivate, ihre darstellung und verwendung als antagonisten von ampa-rezeptoren
JPH10506620A (ja) * 1994-09-16 1998-06-30 ノボ ノルディスク アクティーゼルスカブ 〔1,2,4〕トリアゾロ〔4,3−a〕キノキサリノン誘導体、それらの調製方法及び使用
US5679680A (en) * 1995-02-16 1997-10-21 Warner-Lambert Company α-substituted hydrazides having calpain inhibitory activity
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
WO1999024434A1 (en) 1997-11-11 1999-05-20 Ono Pharmaceutical Co., Ltd. Fused pyrazine compounds
AU2298399A (en) * 1998-02-06 1999-08-23 Yoshitomi Pharmaceutical Industries, Ltd. Novel azapeptide type hydroxamic acid derivatives
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
WO2008072779A1 (ja) * 2006-12-13 2008-06-19 Aska Pharmaceutical Co., Ltd. キノキサリン誘導体
AU2010219598A1 (en) 2009-03-05 2011-09-22 Astellas Pharma Inc. Quinoxaline compounds
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CA2810659A1 (en) 2010-09-07 2012-03-15 Astellas Pharma Inc. Quinoxaline compound
EP2723744B1 (en) * 2011-06-27 2016-03-23 Janssen Pharmaceutica, N.V. 1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES
ES2855575T3 (es) 2012-06-26 2021-09-23 Janssen Pharmaceutica Nv Combinaciones que comprenden compuestos de 4-metil-[1,2,4]triazolo[4,3-a]quinoxalina como inhibidores de PDE2 e inhibidores de PDE10 para su uso en el tratamiento de trastornos neurológicos o metabólicos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
US4547501A (en) * 1983-09-02 1985-10-15 Pfizer Inc. Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
AU3767793A (en) * 1992-04-03 1993-11-08 Yamanouchi Pharmaceutical Co., Ltd. Fused quinoxalinone derivative and pharmaceutical composition containing the same

Also Published As

Publication number Publication date
IL108800A (en) 1998-02-22
KR100313051B1 (ko) 2002-02-28
HU9502726D0 (en) 1995-11-28
IL108800A0 (en) 1994-06-24
AU685783B2 (en) 1998-01-29
EP0691969A1 (en) 1996-01-17
US5559106A (en) 1996-09-24
CN1041930C (zh) 1999-02-03
DK31093D0 (ko) 1993-03-19
TW304195B (ko) 1997-05-01
NO953673D0 (no) 1995-09-18
WO1994021639A1 (en) 1994-09-29
CN1122601A (zh) 1996-05-15
NO305286B1 (no) 1999-05-03
HUT73419A (en) 1996-07-29
JPH08507536A (ja) 1996-08-13
FI954386A (fi) 1995-09-18
FI954386A0 (fi) 1995-09-18
NZ262365A (en) 1997-05-26
NO953673L (no) 1995-11-17
KR960701057A (ko) 1996-02-24
CA2158545A1 (en) 1994-09-29
AU6201894A (en) 1994-10-11

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