ATE190616T1 - (1,2,4)triazolo(4,3-a)chinoxylinonderivate, ihre darstellung und verwendung als antagonisten von ampa-rezeptoren - Google Patents

(1,2,4)triazolo(4,3-a)chinoxylinonderivate, ihre darstellung und verwendung als antagonisten von ampa-rezeptoren

Info

Publication number
ATE190616T1
ATE190616T1 AT95930409T AT95930409T ATE190616T1 AT E190616 T1 ATE190616 T1 AT E190616T1 AT 95930409 T AT95930409 T AT 95930409T AT 95930409 T AT95930409 T AT 95930409T AT E190616 T1 ATE190616 T1 AT E190616T1
Authority
AT
Austria
Prior art keywords
pct
triazolo
chinoxylinone
antagonists
derivatives
Prior art date
Application number
AT95930409T
Other languages
English (en)
Inventor
Flemming Elmelund Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE190616T1 publication Critical patent/ATE190616T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT95930409T 1994-09-16 1995-09-12 (1,2,4)triazolo(4,3-a)chinoxylinonderivate, ihre darstellung und verwendung als antagonisten von ampa-rezeptoren ATE190616T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK106594 1994-09-16
PCT/DK1995/000364 WO1996008492A1 (en) 1994-09-16 1995-09-12 [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE

Publications (1)

Publication Number Publication Date
ATE190616T1 true ATE190616T1 (de) 2000-04-15

Family

ID=8100599

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95930409T ATE190616T1 (de) 1994-09-16 1995-09-12 (1,2,4)triazolo(4,3-a)chinoxylinonderivate, ihre darstellung und verwendung als antagonisten von ampa-rezeptoren

Country Status (23)

Country Link
US (1) US6001832A (de)
EP (1) EP0783504B1 (de)
JP (1) JPH10505601A (de)
CN (1) CN1083842C (de)
AT (1) ATE190616T1 (de)
AU (1) AU706737B2 (de)
CA (1) CA2200055A1 (de)
CZ (1) CZ285248B6 (de)
DE (1) DE69515680T2 (de)
DK (1) DK0783504T3 (de)
ES (1) ES2146769T3 (de)
FI (1) FI971075A (de)
GR (1) GR3033642T3 (de)
HU (1) HUT76810A (de)
IL (1) IL115300A (de)
NO (1) NO308796B1 (de)
NZ (1) NZ292107A (de)
PL (1) PL319176A1 (de)
PT (1) PT783504E (de)
RU (1) RU2149162C1 (de)
SK (1) SK282635B6 (de)
WO (1) WO1996008492A1 (de)
ZA (1) ZA957795B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024434A1 (en) 1997-11-11 1999-05-20 Ono Pharmaceutical Co., Ltd. Fused pyrazine compounds
KR101563103B1 (ko) * 2006-12-13 2015-10-23 아스카 세이야쿠 가부시키가이샤 퀴녹살린 유도체
US8357688B2 (en) 2009-03-05 2013-01-22 Astellas Pharma Inc. Substituted imidazo[1,5-a]quinoxalin-4(5H)-ones as PDE9 inhibitors
ES2747423T3 (es) 2010-09-07 2020-03-10 Astellas Pharma Inc Compuesto de quinoxalina
BR112013005855A2 (pt) * 2010-09-16 2016-05-17 Hutchison Medipharma Ltd heteroarilas fundidas e seus usos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
AU3767793A (en) * 1992-04-03 1993-11-08 Yamanouchi Pharmaceutical Co., Ltd. Fused quinoxalinone derivative and pharmaceutical composition containing the same
DK31093D0 (de) * 1993-03-19 1993-03-19 Novo Nordisk As
WO1994026746A1 (en) * 1993-05-06 1994-11-24 Novo Nordisk A/S [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE

Also Published As

Publication number Publication date
IL115300A (en) 2001-06-14
DE69515680D1 (de) 2000-04-20
DK0783504T3 (da) 2000-08-14
CZ75497A3 (en) 1997-08-13
SK282635B6 (sk) 2002-10-08
NZ292107A (en) 1999-02-25
PT783504E (pt) 2000-08-31
NO308796B1 (no) 2000-10-30
DE69515680T2 (de) 2000-10-19
FI971075A0 (fi) 1997-03-14
JPH10505601A (ja) 1998-06-02
HUT76810A (en) 1997-11-28
CA2200055A1 (en) 1996-03-21
EP0783504A1 (de) 1997-07-16
RU2149162C1 (ru) 2000-05-20
NO971186D0 (no) 1997-03-14
CZ285248B6 (cs) 1999-06-16
US6001832A (en) 1999-12-14
CN1193974A (zh) 1998-09-23
ES2146769T3 (es) 2000-08-16
ZA957795B (en) 1996-05-14
AU706737B2 (en) 1999-06-24
GR3033642T3 (en) 2000-10-31
AU3380795A (en) 1996-03-29
EP0783504B1 (de) 2000-03-15
SK33597A3 (en) 1998-02-04
PL319176A1 (en) 1997-08-04
WO1996008492A1 (en) 1996-03-21
CN1083842C (zh) 2002-05-01
NO971186L (no) 1997-05-15
IL115300A0 (en) 1995-12-31
FI971075A (fi) 1997-05-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee