ZA937827B - Piperazine derivatives - Google Patents

Piperazine derivatives

Info

Publication number
ZA937827B
ZA937827B ZA937827A ZA937827A ZA937827B ZA 937827 B ZA937827 B ZA 937827B ZA 937827 A ZA937827 A ZA 937827A ZA 937827 A ZA937827 A ZA 937827A ZA 937827 B ZA937827 B ZA 937827B
Authority
ZA
South Africa
Prior art keywords
pct
date
piperazine derivatives
sec
formula
Prior art date
Application number
ZA937827A
Other languages
English (en)
Inventor
Ian Anthony Cliffe
Allan Fletcher
Alan Chapman White
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of ZA937827B publication Critical patent/ZA937827B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA937827A 1992-11-05 1993-10-21 Piperazine derivatives ZA937827B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929223153A GB9223153D0 (en) 1992-11-05 1992-11-05 Piperazine derivatives

Publications (1)

Publication Number Publication Date
ZA937827B true ZA937827B (en) 1995-04-21

Family

ID=10724559

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA937827A ZA937827B (en) 1992-11-05 1993-10-21 Piperazine derivatives

Country Status (18)

Country Link
US (1) US5827847A (es)
EP (1) EP0877612B1 (es)
JP (1) JP3238153B2 (es)
AT (1) ATE195422T1 (es)
AU (1) AU682155B2 (es)
CA (1) CA2148593C (es)
DE (1) DE69329252T2 (es)
DK (1) DK0877612T3 (es)
ES (1) ES2149216T3 (es)
GB (1) GB9223153D0 (es)
GR (1) GR3034400T3 (es)
HU (1) HUT72049A (es)
LV (1) LV12734B (es)
MX (1) MX9306879A (es)
PT (1) PT877612E (es)
TW (1) TW252043B (es)
WO (1) WO1994009780A1 (es)
ZA (1) ZA937827B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0710481A1 (en) * 1994-11-02 1996-05-08 Duphar International Research B.V Use of flesinoxan for cognition enhancement
US6271234B1 (en) * 1997-08-01 2001-08-07 Recordati S.A., Chemical And Pharmaceutical Company 1,4-disubstituted piperazines

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2355502A1 (fr) * 1976-06-23 1978-01-20 Roussel Uclaf Application a titre de medicaments d'un derive de la piperazine et de ses sels
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
GB2222768B (en) * 1988-06-17 1992-01-22 Nat Res Dev Analgesic compounds and compositions
GB8909209D0 (en) * 1989-04-22 1989-06-07 Wyeth John & Brother Ltd Piperazine derivatives
US4902687A (en) * 1989-03-27 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
NZ233398A (en) * 1989-04-22 1991-12-23 American Home Prod Aryl- or heteroaryl-substituted piperazine derivatives and pharmaceutical compositions
ATE179973T1 (de) * 1989-04-22 1999-05-15 Wyeth John & Brother Ltd Piperazin-derivate
EP0398413A1 (en) * 1989-05-16 1990-11-22 Duphar International Research B.V "3,4-dehydropiperidine derivatives having psychotropic activity
DK0510068T3 (da) * 1990-01-11 1999-10-25 Upjohn Co Nye 6,7,8,9-tetrahydro-3H-benz(e)indol-heterocycler med virkning på centralnervesystemet
GB9022820D0 (en) * 1990-10-19 1990-12-05 Wyeth John & Brother Ltd Piperazine derivatives
DE4039631A1 (de) * 1990-12-12 1992-06-17 Troponwerke Gmbh & Co Kg Neuroprotektive kombination
IL101722A (en) * 1991-05-02 1996-05-14 Wyeth John & Brother Ltd History of piperazine, their preparation and pharmaceutical preparations containing them
DE4135551A1 (de) * 1991-08-31 1993-03-04 Schering Ag Verwendung von antagonisten oder partiellen agonisten am 5-ht1a-rezeptor zur behandlung und praevention von kognitiven stoerungen

Also Published As

Publication number Publication date
CA2148593A1 (en) 1994-05-11
JPH08502743A (ja) 1996-03-26
DE69329252D1 (de) 2000-09-21
GB9223153D0 (en) 1992-12-16
EP0877612A1 (en) 1998-11-18
ATE195422T1 (de) 2000-09-15
HUT72049A (en) 1996-03-28
DE69329252T2 (de) 2001-03-29
GR3034400T3 (en) 2000-12-29
AU5342194A (en) 1994-05-24
AU682155B2 (en) 1997-09-25
WO1994009780A1 (en) 1994-05-11
HU9501290D0 (en) 1995-06-28
US5827847A (en) 1998-10-27
JP3238153B2 (ja) 2001-12-10
TW252043B (es) 1995-07-21
LV12734B (en) 2002-01-20
LV12734A (en) 2001-10-20
ES2149216T3 (es) 2000-11-01
DK0877612T3 (da) 2000-10-09
MX9306879A (es) 1995-01-31
EP0877612B1 (en) 2000-08-16
CA2148593C (en) 2005-12-06
PT877612E (pt) 2000-11-30

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