ZA935341B - Phenylimidazolidine derivatives, their preparation and their use - Google Patents

Phenylimidazolidine derivatives, their preparation and their use

Info

Publication number
ZA935341B
ZA935341B ZA935341A ZA935341A ZA935341B ZA 935341 B ZA935341 B ZA 935341B ZA 935341 A ZA935341 A ZA 935341A ZA 935341 A ZA935341 A ZA 935341A ZA 935341 B ZA935341 B ZA 935341B
Authority
ZA
South Africa
Prior art keywords
preparation
phenylimidazolidine
derivatives
phenylimidazolidine derivatives
nhr
Prior art date
Application number
ZA935341A
Other languages
English (en)
Inventor
Gerhard Zoller
Bernd Jablonka
Melitta Just Otmar Klingler
Gerhard Breipohl
Jochen Knolle Wolfgang Koenig
Original Assignee
Cassella Farbwerke Mainkur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag
Publication of ZA935341B publication Critical patent/ZA935341B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/40—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA935341A 1992-07-24 1993-07-23 Phenylimidazolidine derivatives, their preparation and their use ZA935341B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4224414A DE4224414A1 (de) 1992-07-24 1992-07-24 Phenylimidazolidin-derivate, ihre Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
ZA935341B true ZA935341B (en) 1994-02-14

Family

ID=6463969

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA935341A ZA935341B (en) 1992-07-24 1993-07-23 Phenylimidazolidine derivatives, their preparation and their use

Country Status (16)

Country Link
US (1) US5424293A (ko)
EP (1) EP0580008B1 (ko)
JP (1) JP3775808B2 (ko)
KR (1) KR100418321B1 (ko)
AT (1) ATE168116T1 (ko)
AU (1) AU664630B2 (ko)
CA (1) CA2101179C (ko)
CZ (1) CZ289297B6 (ko)
DE (2) DE4224414A1 (ko)
DK (1) DK0580008T3 (ko)
ES (1) ES2119837T3 (ko)
HU (1) HU220767B1 (ko)
IL (1) IL106462A (ko)
SK (1) SK282517B6 (ko)
TW (1) TW306918B (ko)
ZA (1) ZA935341B (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4308034A1 (de) * 1993-03-13 1994-09-15 Cassella Ag Neue Heterocyclen, ihre Herstellung und ihre Verwendung
DE4427979A1 (de) 1993-11-15 1996-02-15 Cassella Ag Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung
US5849736A (en) * 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
US5563158A (en) * 1993-12-28 1996-10-08 The Dupont Merck Pharmaceutical Company Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists
ZA963391B (en) * 1995-05-24 1997-10-29 Du Pont Merck Pharma Isoxazoline fibrinogen receptor antagonists.
EP0796855B1 (de) 1996-03-20 2002-02-06 Hoechst Aktiengesellschaft Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19622489A1 (de) 1996-06-05 1997-12-11 Hoechst Ag Salze des 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4- methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3- phenyl-propionsäure-ethylesters
PL323130A1 (en) * 1996-11-15 1998-05-25 Hoechst Ag Application of heterocyclic compounds in production of a pharmaceutic agent, novel heterocyclic compounds and pharmaceutic agent as such
DE19647381A1 (de) 1996-11-15 1998-05-20 Hoechst Ag Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
DE19647380A1 (de) * 1996-11-15 1998-05-20 Hoechst Ag 5-Ring-Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
DE19741235A1 (de) * 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) * 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US6163155A (en) * 1999-01-28 2000-12-19 Dresser Industries, Inc. Electromagnetic wave resistivity tool having a tilted antenna for determining the horizontal and vertical resistivities and relative dip angle in anisotropic earth formations
DE19922462A1 (de) 1999-05-17 2000-11-23 Aventis Pharma Gmbh Spiro-imidazolidinderivate, ihre Herstellung ihre Verwendung und sie enthaltende pharmazeutische Präparate
US6569876B1 (en) 1999-06-17 2003-05-27 John C. Cheronis Method and structure for inhibiting activity of serine elastases
DE10111877A1 (de) 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10137595A1 (de) * 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
CN101501297B (zh) * 2006-07-11 2013-10-16 哈里伯顿能源服务公司 模块化地质导向工具组件
CN101479628B (zh) * 2006-07-12 2012-10-03 哈里伯顿能源服务公司 用于制造倾斜天线的方法和装置
AU2007349251B2 (en) * 2007-03-16 2011-02-24 Halliburton Energy Services, Inc. Robust inversion systems and methods for azimuthally sensitive resistivity logging tools
US8581592B2 (en) 2008-12-16 2013-11-12 Halliburton Energy Services, Inc. Downhole methods and assemblies employing an at-bit antenna
GB2486759B (en) 2010-01-22 2014-09-03 Halliburton Energy Serv Inc Method and apparatus for resistivity measurements
AU2012383577B2 (en) 2012-06-25 2015-07-09 Halliburton Energy Services, Inc. Tilted antenna logging systems and methods yielding robust measurement signals
EP3286172B1 (en) 2015-04-23 2019-06-12 Constellation Pharmaceuticals, Inc. Lsd1 inhibitors and uses thereof
PL3532459T3 (pl) 2016-10-26 2024-06-24 Constellation Pharmaceuticals, Inc. Inhibitory lsd1 i ich zastosowania medyczne

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4126277A1 (de) * 1991-08-08 1993-02-11 Cassella Ag Hydantoinderivate
DE4213634A1 (de) * 1992-04-24 1993-10-28 Cassella Ag 2,4-Dioxo-imidazolidin-Derivate

Also Published As

Publication number Publication date
DE59308732D1 (de) 1998-08-13
JPH0725855A (ja) 1995-01-27
AU4211993A (en) 1994-01-27
CA2101179C (en) 2003-10-28
SK282517B6 (sk) 2002-10-08
IL106462A0 (en) 1993-11-15
EP0580008A3 (de) 1995-03-15
ES2119837T3 (es) 1998-10-16
AU664630B2 (en) 1995-11-23
EP0580008B1 (de) 1998-07-08
JP3775808B2 (ja) 2006-05-17
EP0580008A2 (de) 1994-01-26
DK0580008T3 (da) 1999-02-08
CA2101179A1 (en) 1994-01-25
HU9302138D0 (en) 1993-10-28
IL106462A (en) 1997-02-18
DE4224414A1 (de) 1994-01-27
KR100418321B1 (ko) 2004-05-07
SK76993A3 (en) 1994-04-06
TW306918B (ko) 1997-06-01
ATE168116T1 (de) 1998-07-15
CZ289297B6 (cs) 2001-12-12
CZ147593A3 (en) 1994-03-16
HUT65141A (en) 1994-04-28
US5424293A (en) 1995-06-13
HU220767B1 (hu) 2002-05-28
KR940005583A (ko) 1994-03-21

Similar Documents

Publication Publication Date Title
ZA935341B (en) Phenylimidazolidine derivatives, their preparation and their use
BG100951A (en) Novel erythromycin derivatives, method for their preparation and their use as drugs
AU583055B2 (en) Tetralin derivatives, their preparation and their use
EG19999A (en) Process for preparing of piperazinyl - and piperidinyl cyclohexanols
TW248559B (ko)
CA2080249A1 (en) Preparation of substituted piperidines
AU4611589A (en) Enzyme-inhibiting amino acid derivatives, a process for the preparation thereof, agents containing these, and the use thereof.
NZ216750A (en) Morpholino derivatives and fungicides
AU1413788A (en) Dihydropyridinamides process for their preparation, and their use in medicaments
AU579869B2 (en) 4-amino-8-alkylthio-2-piperazino-pyrimido ``5,4-d`` pyrimidines
ZA88446B (en) Allylmercaptoacetylsydnonimines,processes for their preparation, and their use
KR960004860B1 (en) Substituted pyridine-2,4-dicarboxylic acid compounds and the use thereof and medicaments
DE3783009D1 (ko)
ES2001665A6 (es) Procedimiento para preparar tripeptidos alquilados en n
HU9300181D0 (en) Alpha-aryl-alpha-hydroxi-beta-imidazolinyl-propionic acid amide
HUT73562A (en) Thiocarbamoyl-pyrazole derivatives, keto-carboxylic acid ester intermediates thereof, preparations thereof, using the pyrazole derivatives and microbicide compositions containing these compounds
AU4370489A (en) The use of oxidized polyamines, especially nn'-bis-(3- propionaldehyde)-1-4-diaminobutane (sperminedialdehyde) as immunosuppressive agents
IE893533L (en) Substituted 3-aminosydnonimines, processes for their¹preparation and their use
ZA874596B (en) 3-substituted 1-(2-halogenoalkoxy-benzenesulphonyl)-3-heteroaryl-(thio)ureas
ES2000283A6 (es) Procedimiento para preparar nuevas cetoaminas cicloalifaticas
CA2012661A1 (en) Thienylpiperazines, process for the Preparation Thereof, the Use Thereof, and Pharmaceuticals Containing These and the Preparation Thereof
ES8703421A1 (es) Procedimiento para preparar derivados de pirrolidindiona.