ZA93482B - 4-aryl-3-(heteroarylureido)-1, 2-dihydro-2-oxoquinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents - Google Patents
4-aryl-3-(heteroarylureido)-1, 2-dihydro-2-oxoquinoline derivatives as antihypercholesterolemic and antiatherosclerotic agentsInfo
- Publication number
- ZA93482B ZA93482B ZA93482A ZA93482A ZA93482B ZA 93482 B ZA93482 B ZA 93482B ZA 93482 A ZA93482 A ZA 93482A ZA 93482 A ZA93482 A ZA 93482A ZA 93482 B ZA93482 B ZA 93482B
- Authority
- ZA
- South Africa
- Prior art keywords
- formula
- nitrogen
- group
- compounds
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82463992A | 1992-01-23 | 1992-01-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA93482B true ZA93482B (en) | 1994-07-22 |
Family
ID=25241935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA93482A ZA93482B (en) | 1992-01-23 | 1993-01-22 | 4-aryl-3-(heteroarylureido)-1, 2-dihydro-2-oxoquinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0623112B1 (de) |
JP (1) | JP2668163B2 (de) |
KR (1) | KR950700284A (de) |
AT (1) | ATE175196T1 (de) |
AU (1) | AU3323393A (de) |
CA (1) | CA2128093C (de) |
DE (1) | DE69228069T2 (de) |
DK (1) | DK0623112T3 (de) |
ES (1) | ES2125325T3 (de) |
FI (2) | FI930264A (de) |
HU (1) | HUT63625A (de) |
IL (1) | IL104420A0 (de) |
MX (1) | MX9300361A (de) |
NO (1) | NO942757D0 (de) |
WO (1) | WO1993015058A1 (de) |
ZA (1) | ZA93482B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
CA2321237A1 (en) * | 1998-02-25 | 1999-09-02 | Masami Muraoka | Pyridone derivatives and process for producing the same |
US6452008B2 (en) | 1998-02-25 | 2002-09-17 | Sumitomo Pharmaceuticals Company, Limited | Pyridone derivatives and process for preparing the same |
EP1263421B1 (de) | 2000-02-02 | 2005-05-18 | Warner-Lambert Company LLC | Der duale inhibitor der cholesterylester und wachsester synthese avasimibe zur behandlung von erkrankungen des talgdrüse |
US8309562B2 (en) | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
CA2572442A1 (fr) * | 2004-07-30 | 2006-03-09 | Palumed S.A. | Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien |
FR2874922A1 (fr) * | 2004-07-30 | 2006-03-10 | Palumed Sa | Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien |
CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
MX22406A (es) * | 1989-09-15 | 1994-01-31 | Pfizer | Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat). |
TW205037B (de) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
WO1991012249A1 (en) * | 1990-02-10 | 1991-08-22 | Takeda Chemical Industries, Ltd. | Chromene derivatives, their production and use |
JPH0776215B2 (ja) * | 1991-04-26 | 1995-08-16 | フアイザー・インコーポレイテツド | 4−アリール−3−(ヘテロアリールウレイド)キノリン誘導体 |
-
1992
- 1992-12-21 ES ES93901257T patent/ES2125325T3/es not_active Expired - Lifetime
- 1992-12-21 AT AT93901257T patent/ATE175196T1/de not_active IP Right Cessation
- 1992-12-21 EP EP93901257A patent/EP0623112B1/de not_active Expired - Lifetime
- 1992-12-21 DK DK93901257T patent/DK0623112T3/da active
- 1992-12-21 JP JP5513207A patent/JP2668163B2/ja not_active Expired - Fee Related
- 1992-12-21 WO PCT/US1992/010886 patent/WO1993015058A1/en active IP Right Grant
- 1992-12-21 DE DE69228069T patent/DE69228069T2/de not_active Expired - Fee Related
- 1992-12-21 CA CA002128093A patent/CA2128093C/en not_active Expired - Fee Related
- 1992-12-21 AU AU33233/93A patent/AU3323393A/en not_active Abandoned
-
1993
- 1993-01-18 IL IL104420A patent/IL104420A0/xx unknown
- 1993-01-22 MX MX9300361A patent/MX9300361A/es unknown
- 1993-01-22 HU HU9300197A patent/HUT63625A/hu unknown
- 1993-01-22 FI FI930264A patent/FI930264A/fi unknown
- 1993-01-22 ZA ZA93482A patent/ZA93482B/xx unknown
-
1994
- 1994-07-22 NO NO942757A patent/NO942757D0/no unknown
- 1994-07-22 KR KR1019940702519A patent/KR950700284A/ko not_active Application Discontinuation
-
2001
- 2001-01-12 FI FI20010074A patent/FI20010074A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
JP2668163B2 (ja) | 1997-10-27 |
FI20010074A (fi) | 2001-01-12 |
DE69228069D1 (de) | 1999-02-11 |
ATE175196T1 (de) | 1999-01-15 |
IL104420A0 (en) | 1993-05-13 |
DK0623112T3 (da) | 1999-08-30 |
FI930264A0 (fi) | 1993-01-22 |
FI930264A (fi) | 1993-07-24 |
WO1993015058A1 (en) | 1993-08-05 |
NO942757L (no) | 1994-07-22 |
CA2128093A1 (en) | 1993-08-05 |
ES2125325T3 (es) | 1999-03-01 |
MX9300361A (es) | 1994-06-30 |
AU3323393A (en) | 1993-09-01 |
JPH07503712A (ja) | 1995-04-20 |
EP0623112A1 (de) | 1994-11-09 |
CA2128093C (en) | 1998-02-03 |
EP0623112B1 (de) | 1998-12-30 |
NO942757D0 (no) | 1994-07-22 |
HUT63625A (en) | 1993-09-28 |
KR950700284A (ko) | 1995-01-16 |
DE69228069T2 (de) | 1999-05-20 |
HU9300197D0 (en) | 1993-04-28 |
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