HUT63625A - Process for producing 4-phenyl-3-(heteroarylureido)-1,2-dihydro-2-oxoquinoline derivatives against arteriosclerosis and reducing the cholesterol level - Google Patents

Process for producing 4-phenyl-3-(heteroarylureido)-1,2-dihydro-2-oxoquinoline derivatives against arteriosclerosis and reducing the cholesterol level

Info

Publication number
HUT63625A
HUT63625A HU9300197A HU9300197A HUT63625A HU T63625 A HUT63625 A HU T63625A HU 9300197 A HU9300197 A HU 9300197A HU 9300197 A HU9300197 A HU 9300197A HU T63625 A HUT63625 A HU T63625A
Authority
HU
Hungary
Prior art keywords
formula
nitrogen
group
compounds
optionally substituted
Prior art date
Application number
HU9300197A
Other languages
English (en)
Other versions
HU9300197D0 (en
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU9300197D0 publication Critical patent/HU9300197D0/hu
Publication of HUT63625A publication Critical patent/HUT63625A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU9300197A 1992-01-23 1993-01-22 Process for producing 4-phenyl-3-(heteroarylureido)-1,2-dihydro-2-oxoquinoline derivatives against arteriosclerosis and reducing the cholesterol level HUT63625A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82463992A 1992-01-23 1992-01-23

Publications (2)

Publication Number Publication Date
HU9300197D0 HU9300197D0 (en) 1993-04-28
HUT63625A true HUT63625A (en) 1993-09-28

Family

ID=25241935

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9300197A HUT63625A (en) 1992-01-23 1993-01-22 Process for producing 4-phenyl-3-(heteroarylureido)-1,2-dihydro-2-oxoquinoline derivatives against arteriosclerosis and reducing the cholesterol level

Country Status (16)

Country Link
EP (1) EP0623112B1 (hu)
JP (1) JP2668163B2 (hu)
KR (1) KR950700284A (hu)
AT (1) ATE175196T1 (hu)
AU (1) AU3323393A (hu)
CA (1) CA2128093C (hu)
DE (1) DE69228069T2 (hu)
DK (1) DK0623112T3 (hu)
ES (1) ES2125325T3 (hu)
FI (2) FI930264A (hu)
HU (1) HUT63625A (hu)
IL (1) IL104420A0 (hu)
MX (1) MX9300361A (hu)
NO (1) NO942757L (hu)
WO (1) WO1993015058A1 (hu)
ZA (1) ZA93482B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133326A (en) * 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
WO1999043659A1 (fr) * 1998-02-25 1999-09-02 Sumitomo Pharmaceuticals Co., Ltd. Derives de pyridone et leur procede de fabrication
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
ES2239145T3 (es) 2000-02-02 2005-09-16 Warner-Lambert Company Llc Inhibidor doble de la sintesis de ester de colesterilo y de ester de cera avasimibe para el tratamiento de trastornos de la glandula sebacea.
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
FR2874922A1 (fr) * 2004-07-30 2006-03-10 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
BRPI0514381A (pt) * 2004-07-30 2008-06-10 Palumed Sa compostos hìbridos de aminoquinolina-antibiótico, composições farmacêuticas, método de preparação e uso destes
CA2592900A1 (en) 2005-01-03 2006-07-13 Myriad Genetics Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (hu) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
DE69106499T2 (de) * 1990-02-10 1995-06-29 Takeda Chemical Industries Ltd Chromenderivate, deren herstellung und verwendung.
AU1879792A (en) * 1991-04-26 1992-12-21 Pfizer Inc. 4-aryl-3-(heteroarylureido)quinoline derivatives

Also Published As

Publication number Publication date
HU9300197D0 (en) 1993-04-28
FI20010074A (fi) 2001-01-12
ES2125325T3 (es) 1999-03-01
ZA93482B (en) 1994-07-22
CA2128093A1 (en) 1993-08-05
WO1993015058A1 (en) 1993-08-05
DE69228069D1 (de) 1999-02-11
IL104420A0 (en) 1993-05-13
JPH07503712A (ja) 1995-04-20
DK0623112T3 (da) 1999-08-30
DE69228069T2 (de) 1999-05-20
ATE175196T1 (de) 1999-01-15
EP0623112B1 (en) 1998-12-30
FI930264A0 (fi) 1993-01-22
CA2128093C (en) 1998-02-03
JP2668163B2 (ja) 1997-10-27
NO942757D0 (no) 1994-07-22
FI930264A (fi) 1993-07-24
NO942757L (no) 1994-07-22
AU3323393A (en) 1993-09-01
KR950700284A (ko) 1995-01-16
MX9300361A (es) 1994-06-30
EP0623112A1 (en) 1994-11-09

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee