FI20010074A - Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia - Google Patents

Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia Download PDF

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Publication number
FI20010074A
FI20010074A FI20010074A FI20010074A FI20010074A FI 20010074 A FI20010074 A FI 20010074A FI 20010074 A FI20010074 A FI 20010074A FI 20010074 A FI20010074 A FI 20010074A FI 20010074 A FI20010074 A FI 20010074A
Authority
FI
Finland
Prior art keywords
formula
nitrogen
group
compounds
optionally substituted
Prior art date
Application number
FI20010074A
Other languages
English (en)
Swedish (sv)
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI20010074A publication Critical patent/FI20010074A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI20010074A 1992-01-23 2001-01-12 Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia FI20010074A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82463992A 1992-01-23 1992-01-23

Publications (1)

Publication Number Publication Date
FI20010074A true FI20010074A (fi) 2001-01-12

Family

ID=25241935

Family Applications (2)

Application Number Title Priority Date Filing Date
FI930264A FI930264A (fi) 1992-01-23 1993-01-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel
FI20010074A FI20010074A (fi) 1992-01-23 2001-01-12 Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI930264A FI930264A (fi) 1992-01-23 1993-01-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel

Country Status (16)

Country Link
EP (1) EP0623112B1 (fi)
JP (1) JP2668163B2 (fi)
KR (1) KR950700284A (fi)
AT (1) ATE175196T1 (fi)
AU (1) AU3323393A (fi)
CA (1) CA2128093C (fi)
DE (1) DE69228069T2 (fi)
DK (1) DK0623112T3 (fi)
ES (1) ES2125325T3 (fi)
FI (2) FI930264A (fi)
HU (1) HUT63625A (fi)
IL (1) IL104420A0 (fi)
MX (1) MX9300361A (fi)
NO (1) NO942757L (fi)
WO (1) WO1993015058A1 (fi)
ZA (1) ZA93482B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133326A (en) * 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
AU2547399A (en) * 1998-02-25 1999-09-15 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for producing the same
HUP0301010A3 (en) 2000-02-02 2005-03-29 Warner Lambert Co Dual inhibitors of cholesteryl ester and wax ester synthesis for sebaceous gland disorders and pharmaceutical compositions containing them
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
BRPI0514381A (pt) * 2004-07-30 2008-06-10 Palumed Sa compostos hìbridos de aminoquinolina-antibiótico, composições farmacêuticas, método de preparação e uso destes
FR2874922A1 (fr) * 2004-07-30 2006-03-10 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
CA2592900A1 (en) 2005-01-03 2006-07-13 Myriad Genetics Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (fi) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
EP0514546B1 (en) * 1990-02-10 1995-01-04 Takeda Chemical Industries, Ltd. Chromene derivatives, their production and use
AU1879792A (en) * 1991-04-26 1992-12-21 Pfizer Inc. 4-aryl-3-(heteroarylureido)quinoline derivatives

Also Published As

Publication number Publication date
NO942757D0 (no) 1994-07-22
MX9300361A (es) 1994-06-30
FI930264A (fi) 1993-07-24
ATE175196T1 (de) 1999-01-15
IL104420A0 (en) 1993-05-13
ZA93482B (en) 1994-07-22
AU3323393A (en) 1993-09-01
DK0623112T3 (da) 1999-08-30
JP2668163B2 (ja) 1997-10-27
DE69228069D1 (de) 1999-02-11
EP0623112A1 (en) 1994-11-09
EP0623112B1 (en) 1998-12-30
WO1993015058A1 (en) 1993-08-05
HU9300197D0 (en) 1993-04-28
CA2128093C (en) 1998-02-03
CA2128093A1 (en) 1993-08-05
ES2125325T3 (es) 1999-03-01
JPH07503712A (ja) 1995-04-20
KR950700284A (ko) 1995-01-16
NO942757L (no) 1994-07-22
DE69228069T2 (de) 1999-05-20
HUT63625A (en) 1993-09-28
FI930264A0 (fi) 1993-01-22

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