ZA934602B - Process for the preparation of N-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy) propylamine and acid addition salts thereof - Google Patents

Process for the preparation of N-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy) propylamine and acid addition salts thereof

Info

Publication number
ZA934602B
ZA934602B ZA934602A ZA934602A ZA934602B ZA 934602 B ZA934602 B ZA 934602B ZA 934602 A ZA934602 A ZA 934602A ZA 934602 A ZA934602 A ZA 934602A ZA 934602 B ZA934602 B ZA 934602B
Authority
ZA
South Africa
Prior art keywords
propylamine
phenoxy
trifluoromethyl
phenyl
methyl
Prior art date
Application number
ZA934602A
Other languages
English (en)
Inventor
Csongor Eva Againe
Ferenc Drexler
Trischler Zsuzsanna Aracsne
Kalman Harsanyi
Beatrix Ujvari
Gal Gizella Vargane
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA934602B publication Critical patent/ZA934602B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA934602A 1992-06-26 1993-06-25 Process for the preparation of N-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy) propylamine and acid addition salts thereof ZA934602B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9202128A HU9202128D0 (en) 1992-06-26 1992-06-26 Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine

Publications (1)

Publication Number Publication Date
ZA934602B true ZA934602B (en) 1993-12-21

Family

ID=10982105

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA934602A ZA934602B (en) 1992-06-26 1993-06-25 Process for the preparation of N-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy) propylamine and acid addition salts thereof

Country Status (10)

Country Link
AU (1) AU4352893A (xx)
BE (1) BE1006426A6 (xx)
FR (1) FR2692890A1 (xx)
GR (1) GR930100279A (xx)
HU (1) HU9202128D0 (xx)
IE (1) IE930475A1 (xx)
IL (1) IL106140A0 (xx)
IT (1) ITMI931299A1 (xx)
WO (1) WO1994000416A1 (xx)
ZA (1) ZA934602B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
ES2101650B1 (es) * 1995-06-29 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina.
ES2101654B1 (es) * 1995-07-24 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2101655B1 (es) * 1995-07-28 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2103680B1 (es) * 1995-08-03 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina.
ES2103681B1 (es) * 1995-09-19 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina.
ES2120368B1 (es) * 1996-06-14 1999-07-01 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.
IT1283141B1 (it) * 1996-07-11 1998-04-07 Laporte Organics Francis S P A Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi
US5892117A (en) * 1997-06-12 1999-04-06 Albemarle Corporation Preparation and uses of N-methylnitrone
US5998627A (en) * 1997-08-04 1999-12-07 Albemarle Corporation Preparation and uses of hydrocarbylnitrones
TW514634B (en) * 1997-10-14 2002-12-21 Lilly Co Eli Process to make chiral compounds
US5936124A (en) * 1998-06-22 1999-08-10 Sepacor Inc. Fluoxetine process from benzoylpropionic acid
US6025517A (en) * 1998-08-03 2000-02-15 Sepracor Inc. Fluoxetine process from benzoylacetonitrile
US6677485B2 (en) 1999-12-17 2004-01-13 Ranbaxy Laboratories Limited Process for the preparation of fluoxetine hydrochloride
US6258853B1 (en) 2001-01-31 2001-07-10 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310251B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6313350B1 (en) 2001-01-31 2001-11-06 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6316672B1 (en) 2001-01-31 2001-11-13 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310250B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form A of fluoxetine hydrochloride
US6846957B2 (en) 2002-11-22 2005-01-25 Board Of Regents, The University Of Texas System Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor
US7439399B2 (en) 2004-06-28 2008-10-21 Teva Pharmaceutical Fine Chemicals Processes for the preparation of atomoxetine hydrochloride
ES2313387T3 (es) 2004-06-28 2009-03-01 Teva Pharmaceutical Fine Chemicals S.R.L. Impureza de atomoxetina aislada, procedimiento para la preparacion de impurezas de atomoxetina y su utilizacion como patrones de referencia.
EP1768949A2 (en) 2004-07-22 2007-04-04 Teva Pharmaceutical Fine Chemicals S.R.L. Polymorphs of atomoxetiene hydrochloride
US7569729B2 (en) * 2005-04-05 2009-08-04 Teva Pharmaceutical Fine Chemicals S.R.L. Stable atomoxetine hydrochloride, a process for the preparation thereof, and an analytical control of its stability
US7485754B2 (en) 2005-07-08 2009-02-03 Apotex Pharmachem Inc. Efficient method for preparing 3-aryloxy-3-arylpropylamines and their optical stereoisomers
EP1971591A2 (en) 2005-12-12 2008-09-24 Medichem, S.A. Improved synthesis and preparations of duloxetine salts

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB2060618A (en) * 1979-09-14 1981-05-07 Wyeth John & Brother Ltd 3-Aryl-3-Aryloxypropylamines
FI81083C (fi) * 1989-03-03 1990-09-10 Orion Yhtymae Oy Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid.
JP2707148B2 (ja) * 1990-04-20 1998-01-28 チッソ株式会社 光学活性フルオキセチンの製造方法とこの方法に使用する化合物

Also Published As

Publication number Publication date
ITMI931299A0 (it) 1993-06-16
GR930100279A (el) 1994-02-28
IE930475A1 (en) 1993-12-29
BE1006426A6 (fr) 1994-08-23
AU4352893A (en) 1994-01-24
WO1994000416A1 (en) 1994-01-06
FR2692890A1 (fr) 1993-12-31
IL106140A0 (en) 1993-10-20
HU9202128D0 (en) 1992-10-28
ITMI931299A1 (it) 1993-12-27

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