ITMI931299A0 - Procedimento per la preparazione di n-metil-3-fenil-(4-trifluororo metil)fenossi) propilammina e di suoi sali acidi di addizione - Google Patents
Procedimento per la preparazione di n-metil-3-fenil-(4-trifluororo metil)fenossi) propilammina e di suoi sali acidi di addizioneInfo
- Publication number
- ITMI931299A0 ITMI931299A0 IT93MI1299A ITMI931299A ITMI931299A0 IT MI931299 A0 ITMI931299 A0 IT MI931299A0 IT 93MI1299 A IT93MI1299 A IT 93MI1299A IT MI931299 A ITMI931299 A IT MI931299A IT MI931299 A0 ITMI931299 A0 IT MI931299A0
- Authority
- IT
- Italy
- Prior art keywords
- methyl
- trifluororo
- propylamine
- phenoxy
- phenyl
- Prior art date
Links
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical compound CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 title 1
- KHUXNRRPPZOJPT-UHFFFAOYSA-N phenoxy radical Chemical compound O=C1C=C[CH]C=C1 KHUXNRRPPZOJPT-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9202128A HU9202128D0 (en) | 1992-06-26 | 1992-06-26 | Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI931299A0 true ITMI931299A0 (it) | 1993-06-16 |
| ITMI931299A1 ITMI931299A1 (it) | 1993-12-27 |
Family
ID=10982105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT93MI001299A ITMI931299A1 (it) | 1992-06-26 | 1993-06-16 | Procedimento per la preparazione di n-metil-3-fenil-3(4-trifluororo metil)fenossi) propilammina e di suoi sali acidi di addizione |
Country Status (10)
| Country | Link |
|---|---|
| AU (1) | AU4352893A (it) |
| BE (1) | BE1006426A6 (it) |
| FR (1) | FR2692890A1 (it) |
| GR (1) | GR930100279A (it) |
| HU (1) | HU9202128D0 (it) |
| IE (1) | IE930475A1 (it) |
| IL (1) | IL106140A0 (it) |
| IT (1) | ITMI931299A1 (it) |
| WO (1) | WO1994000416A1 (it) |
| ZA (1) | ZA934602B (it) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362886A (en) * | 1993-10-12 | 1994-11-08 | Eli Lilly And Company | Asymmetric synthesis |
| ES2101650B1 (es) * | 1995-06-29 | 1998-01-16 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina. |
| ES2101654B1 (es) * | 1995-07-24 | 1998-01-16 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina. |
| ES2101655B1 (es) * | 1995-07-28 | 1998-01-16 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina. |
| ES2103680B1 (es) * | 1995-08-03 | 1998-04-01 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina. |
| ES2103681B1 (es) * | 1995-09-19 | 1998-04-01 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina. |
| ES2120368B1 (es) * | 1996-06-14 | 1999-07-01 | Almirall Prodesfarma Sa | Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables. |
| IT1283141B1 (it) * | 1996-07-11 | 1998-04-07 | Laporte Organics Francis S P A | Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi |
| US5892117A (en) * | 1997-06-12 | 1999-04-06 | Albemarle Corporation | Preparation and uses of N-methylnitrone |
| US5998627A (en) * | 1997-08-04 | 1999-12-07 | Albemarle Corporation | Preparation and uses of hydrocarbylnitrones |
| TW514634B (en) * | 1997-10-14 | 2002-12-21 | Lilly Co Eli | Process to make chiral compounds |
| US5936124A (en) * | 1998-06-22 | 1999-08-10 | Sepacor Inc. | Fluoxetine process from benzoylpropionic acid |
| US6025517A (en) * | 1998-08-03 | 2000-02-15 | Sepracor Inc. | Fluoxetine process from benzoylacetonitrile |
| EP1242362A4 (en) | 1999-12-17 | 2003-07-09 | Ranbaxy Lab Ltd | METHOD FOR PRODUCING FLUOXETINE HYDROCHLORIDE |
| US6316672B1 (en) | 2001-01-31 | 2001-11-13 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6310250B1 (en) | 2001-01-31 | 2001-10-30 | Grayson Walker Stowell | Form A of fluoxetine hydrochloride |
| US6310251B1 (en) | 2001-01-31 | 2001-10-30 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6313350B1 (en) | 2001-01-31 | 2001-11-06 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6258853B1 (en) | 2001-01-31 | 2001-07-10 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6846957B2 (en) | 2002-11-22 | 2005-01-25 | Board Of Regents, The University Of Texas System | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor |
| US7439399B2 (en) | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
| US7439398B2 (en) | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals S.R.L. | Enantiomerically pure atomoxetine and tomoxetine mandelate |
| EP1768949A2 (en) | 2004-07-22 | 2007-04-04 | Teva Pharmaceutical Fine Chemicals S.R.L. | Polymorphs of atomoxetiene hydrochloride |
| JP2008501721A (ja) * | 2005-04-05 | 2008-01-24 | テバ ファーマシューティカル ファイン ケミカルズ ソチエタ レスポンサビリタ リミテ | 安定性アトモキセチン塩酸塩、その調製方法及びその安定性の分析的調節 |
| US7485754B2 (en) | 2005-07-08 | 2009-02-03 | Apotex Pharmachem Inc. | Efficient method for preparing 3-aryloxy-3-arylpropylamines and their optical stereoisomers |
| US20090182156A1 (en) | 2005-12-12 | 2009-07-16 | Stephen Benedict David Winter | Synthesis and preparations of duloxetine salts |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| GB2060618A (en) * | 1979-09-14 | 1981-05-07 | Wyeth John & Brother Ltd | 3-Aryl-3-Aryloxypropylamines |
| FI81083C (fi) * | 1989-03-03 | 1990-09-10 | Orion Yhtymae Oy | Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid. |
| JP2707148B2 (ja) * | 1990-04-20 | 1998-01-28 | チッソ株式会社 | 光学活性フルオキセチンの製造方法とこの方法に使用する化合物 |
-
1992
- 1992-06-26 HU HU9202128A patent/HU9202128D0/hu unknown
-
1993
- 1993-06-16 IT IT93MI001299A patent/ITMI931299A1/it not_active IP Right Cessation
- 1993-06-25 IE IE047593A patent/IE930475A1/en not_active IP Right Cessation
- 1993-06-25 GR GR930100279A patent/GR930100279A/el unknown
- 1993-06-25 BE BE9300657A patent/BE1006426A6/fr not_active IP Right Cessation
- 1993-06-25 IL IL106140A patent/IL106140A0/xx unknown
- 1993-06-25 ZA ZA934602A patent/ZA934602B/xx unknown
- 1993-06-25 FR FR9307756A patent/FR2692890A1/fr not_active Withdrawn
- 1993-06-25 WO PCT/HU1993/000041 patent/WO1994000416A1/en active Application Filing
- 1993-06-26 AU AU43528/93A patent/AU4352893A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GR930100279A (el) | 1994-02-28 |
| ZA934602B (en) | 1993-12-21 |
| FR2692890A1 (fr) | 1993-12-31 |
| ITMI931299A1 (it) | 1993-12-27 |
| IE930475A1 (en) | 1993-12-29 |
| IL106140A0 (en) | 1993-10-20 |
| HU9202128D0 (en) | 1992-10-28 |
| WO1994000416A1 (en) | 1994-01-06 |
| BE1006426A6 (fr) | 1994-08-23 |
| AU4352893A (en) | 1994-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0003 | Withdrawn |