IT1283141B1 - Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi - Google Patents
Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoiInfo
- Publication number
- IT1283141B1 IT1283141B1 IT96MI001438A ITMI961438A IT1283141B1 IT 1283141 B1 IT1283141 B1 IT 1283141B1 IT 96MI001438 A IT96MI001438 A IT 96MI001438A IT MI961438 A ITMI961438 A IT MI961438A IT 1283141 B1 IT1283141 B1 IT 1283141B1
- Authority
- IT
- Italy
- Prior art keywords
- phenylpropylamine
- trifluoromethylphenoxy
- methyl
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96MI001438A IT1283141B1 (it) | 1996-07-11 | 1996-07-11 | Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi |
US08/889,162 US5847214A (en) | 1996-07-11 | 1997-07-07 | Process for preparing N-methyl-3-(P-trifluoromethylphenoxy)-3-phenyl-propylamine and salts thereof in a highly pure form |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96MI001438A IT1283141B1 (it) | 1996-07-11 | 1996-07-11 | Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI961438A0 ITMI961438A0 (it) | 1996-07-11 |
ITMI961438A1 ITMI961438A1 (it) | 1998-01-11 |
IT1283141B1 true IT1283141B1 (it) | 1998-04-07 |
Family
ID=11374574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT96MI001438A IT1283141B1 (it) | 1996-07-11 | 1996-07-11 | Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi |
Country Status (2)
Country | Link |
---|---|
US (1) | US5847214A (it) |
IT (1) | IT1283141B1 (it) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5936124A (en) * | 1998-06-22 | 1999-08-10 | Sepacor Inc. | Fluoxetine process from benzoylpropionic acid |
AU1502400A (en) * | 1998-12-21 | 2000-07-12 | Siegfried Cms Ag | Method for producing fluoxetin |
ATE309196T1 (de) * | 1999-04-09 | 2005-11-15 | Lilly Co Eli | Verfahren zur herstellung von 3-aryloxy-3- arylpropylamine und deren zwischenprodukte |
AU4010000A (en) * | 1999-04-26 | 2000-11-10 | Eli Lilly And Company | Epimerization reaction for the production of r-fluoxetine |
US6355807B1 (en) | 1999-08-24 | 2002-03-12 | Agouron Pharmaceuticals, Inc. | Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates |
US20030064429A1 (en) * | 1999-08-24 | 2003-04-03 | Agouron Pharmaceuticals, Inc. | Efficient methods for the preparation of rhinovirus protease inhibitors, key intermediates and a continuous membrane reactor useful for preparing the same |
US6774243B2 (en) | 1999-08-24 | 2004-08-10 | Agouron Pharmaceuticals, Inc. | Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates |
CN1124254C (zh) * | 2000-10-26 | 2003-10-15 | 中国科学院成都有机化学研究所 | 光学纯氟西汀的制备方法 |
US6313350B1 (en) | 2001-01-31 | 2001-11-06 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
US6310251B1 (en) | 2001-01-31 | 2001-10-30 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
US6258853B1 (en) | 2001-01-31 | 2001-07-10 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
US6310250B1 (en) | 2001-01-31 | 2001-10-30 | Grayson Walker Stowell | Form A of fluoxetine hydrochloride |
US6316672B1 (en) | 2001-01-31 | 2001-11-13 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
EP1596869B1 (en) * | 2003-01-21 | 2014-06-04 | New Form Pharmaceuticals Inc. | Novel cocrystallization |
EP1740930A4 (en) | 2004-03-12 | 2010-09-15 | Aptuit Kansas City Llc | SEARCH FOR FORMATS BY ULTRASOUND CRYSTALLIZATION AND COKRISTALLIZATION USING ULTRASOUND |
WO2006037055A1 (en) * | 2004-09-27 | 2006-04-06 | Dr. Reddy's Laboratories Ltd. | Synthesis of atomoxetine hydrochloride |
US7485754B2 (en) * | 2005-07-08 | 2009-02-03 | Apotex Pharmachem Inc. | Efficient method for preparing 3-aryloxy-3-arylpropylamines and their optical stereoisomers |
CN113968793A (zh) * | 2021-10-27 | 2022-01-25 | 盐城迪赛诺制药有限公司 | 一种提高依非韦伦关键中间体母液纯度的精制方法 |
CN115073310A (zh) * | 2022-07-05 | 2022-09-20 | 盐城迪赛诺制药有限公司 | 一种降低依非韦伦关键中间体母液中特定杂质的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
US5166437A (en) * | 1989-03-03 | 1992-11-24 | Orion-Yhtyma Oy | Process for the preparation of fluoxetine |
HU9202128D0 (en) * | 1992-06-26 | 1992-10-28 | Richter Gedeon Vegyeszet | Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine |
US5618968A (en) * | 1993-02-05 | 1997-04-08 | Pliva Farmaceutska Kemijska, Prehrambena I Kozmeticka Industrija, Dionicko Drustvo | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation |
-
1996
- 1996-07-11 IT IT96MI001438A patent/IT1283141B1/it active IP Right Grant
-
1997
- 1997-07-07 US US08/889,162 patent/US5847214A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ITMI961438A0 (it) | 1996-07-11 |
US5847214A (en) | 1998-12-08 |
ITMI961438A1 (it) | 1998-01-11 |
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Legal Events
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0001 | Granted |