ZA92695B - The use of thiazolo-(2,3-a)-isoindole derivatives as antiviral pharmaceuticals and new thiazolo-(2,3-a)-isoindole derivatives - Google Patents
The use of thiazolo-(2,3-a)-isoindole derivatives as antiviral pharmaceuticals and new thiazolo-(2,3-a)-isoindole derivativesInfo
- Publication number
- ZA92695B ZA92695B ZA92695A ZA92695A ZA92695B ZA 92695 B ZA92695 B ZA 92695B ZA 92695 A ZA92695 A ZA 92695A ZA 92695 A ZA92695 A ZA 92695A ZA 92695 B ZA92695 B ZA 92695B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiazolo
- isoindole derivatives
- isoindole
- derivatives
- new
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 125000000904 isoindolyl group Chemical class C=1(NC=C2C=CC=CC12)* 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 206010038997 Retroviral infections Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4103177A DE4103177A1 (de) | 1991-02-02 | 1991-02-02 | Thiazolo-(2,3-a)isoindol-derivate und diese enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA92695B true ZA92695B (en) | 1992-11-25 |
Family
ID=6424264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA92695A ZA92695B (en) | 1991-02-02 | 1992-01-31 | The use of thiazolo-(2,3-a)-isoindole derivatives as antiviral pharmaceuticals and new thiazolo-(2,3-a)-isoindole derivatives |
Country Status (14)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5527819A (en) * | 1991-09-06 | 1996-06-18 | Merck & Co., Inc. | Inhibitors of HIV reverse transcriptase |
| DE4129779A1 (de) * | 1991-09-07 | 1993-03-11 | Boehringer Mannheim Gmbh | Neue tricyclische thiazol- und oxazol-derivate und diese enthaltende arzneimittel |
| DE4214830A1 (de) * | 1992-05-10 | 1993-11-11 | Boehringer Mannheim Gmbh | Neue Tricyclische Thiazolo- und Thiazino-Derivate und diese enthaltende Arzneimittel |
| WO2002066479A1 (fr) * | 2001-02-23 | 2002-08-29 | Banyu Pharmaceutical Co.,Ltd. | Derives de l'isoindole |
| RU2422444C2 (ru) | 2003-12-24 | 2011-06-27 | Байота Сайентифик Менеджмент Пти Лтд | Полициклические средства для лечения респираторно-синцитиальных вирусных инфекций |
| AR057623A1 (es) | 2005-11-28 | 2007-12-05 | Omega Bio Pharma H K Ltd | Materiales y metodos para el tratamiento de las infecciones virales |
| TWI423972B (zh) | 2006-09-28 | 2014-01-21 | Biota Scient Management | 治療呼吸系融合細胞病毒感染之多環劑 |
| TWI508968B (zh) | 2010-02-08 | 2015-11-21 | Biota Scient Management | 用於治療呼吸道融合性病毒感染的化合物 |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH433321A (de) * | 1964-02-11 | 1967-04-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen |
| CH469733A (de) * | 1965-07-27 | 1969-03-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen |
-
1991
- 1991-02-02 DE DE4103177A patent/DE4103177A1/de not_active Withdrawn
-
1992
- 1992-01-28 EP EP92904272A patent/EP0569457B1/de not_active Expired - Lifetime
- 1992-01-28 JP JP4503931A patent/JPH06505229A/ja active Pending
- 1992-01-28 ES ES92904272T patent/ES2075684T3/es not_active Expired - Lifetime
- 1992-01-28 WO PCT/EP1992/000172 patent/WO1992013863A1/de active IP Right Grant
- 1992-01-28 DE DE59202551T patent/DE59202551D1/de not_active Expired - Fee Related
- 1992-01-28 AU AU12048/92A patent/AU1204892A/en not_active Abandoned
- 1992-01-28 CA CA002100366A patent/CA2100366A1/en not_active Abandoned
- 1992-01-28 AT AT92904272T patent/ATE123779T1/de active
- 1992-01-30 TW TW081100700A patent/TW198037B/zh active
- 1992-01-30 IL IL100818A patent/IL100818A0/xx unknown
- 1992-01-31 ZA ZA92695A patent/ZA92695B/xx unknown
- 1992-01-31 IE IE033492A patent/IE920334A1/en not_active Application Discontinuation
- 1992-01-31 MX MX9200446A patent/MX9200446A/es unknown
- 1992-01-31 PT PT100083A patent/PT100083A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992013863A1 (de) | 1992-08-20 |
| PT100083A (pt) | 1994-05-31 |
| EP0569457A1 (de) | 1993-11-18 |
| IL100818A0 (en) | 1992-09-06 |
| EP0569457B1 (de) | 1995-06-14 |
| MX9200446A (es) | 1992-08-01 |
| DE59202551D1 (de) | 1995-07-20 |
| CA2100366A1 (en) | 1992-08-03 |
| TW198037B (enrdf_load_stackoverflow) | 1993-01-11 |
| DE4103177A1 (de) | 1992-08-06 |
| ES2075684T3 (es) | 1995-10-01 |
| ATE123779T1 (de) | 1995-06-15 |
| IE920334A1 (en) | 1992-08-12 |
| JPH06505229A (ja) | 1994-06-16 |
| AU1204892A (en) | 1992-09-07 |
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