AU4065593A - Novel tricyclic thiazolo and thiazino derivatives and anti-viral medicaments containing them - Google Patents
Novel tricyclic thiazolo and thiazino derivatives and anti-viral medicaments containing themInfo
- Publication number
- AU4065593A AU4065593A AU40655/93A AU4065593A AU4065593A AU 4065593 A AU4065593 A AU 4065593A AU 40655/93 A AU40655/93 A AU 40655/93A AU 4065593 A AU4065593 A AU 4065593A AU 4065593 A AU4065593 A AU 4065593A
- Authority
- AU
- Australia
- Prior art keywords
- atoms
- thiazino
- derivatives
- alkyl
- medicaments containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Abstract
The present invention relates to tricyclic thiazolo and thiazino derivatives of formula (I) in which A is a carbocyclic or heterocyclic ring, X may be an oxygen or sulphur atom or the group =NH, =N-C1?-C6? alkyl or =S(O)2?, R is an aliphatic radical with 1-9 C atoms, which may be substituted by phenyl, or a carbocyclic ring with 7-15 C atoms or a heterocyclic ring system, R?1 is a hydrogen atom, an aliphatic radical with 1-6 C atoms or C1?-C6? alkoxy, C1?-C6? alkylmercapto, C1?-C6? alkylsulphinyl, C1?-C6? alkylsulphonyl, amino, C1?-C6? alkylamino, di-C1?-C6? alkylamino, sulphonamido, C1?-C6? alkoxycarbonyl, carboxy, halogen, hydroxy, nitro, cyano, azido, phenyl or benzyloxy, R?2, R?3, R?4 and R?5 may be hydrogen, C1?-C6? alkyl, C1?-C6? hydroxyalkyl, cyano, carboxy or C1?-C6? alkoxycarbonyl and R?2 and R?4 are a further bond between the C atoms to which they are bonded, R?6 is hydrogen or C1?-C6? alkyl, n is 0, 1 or 2 and m is 0 or 1, and their tautomers, enantiomers, diastereomers or physiological acceptable salts. The invention also relates to medicaments containing compounds of formula (I), especially for the treatment of viral infections.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4214830 | 1992-05-10 | ||
DE4214830A DE4214830A1 (en) | 1992-05-10 | 1992-05-10 | New tricyclic thiazolo and thiazino derivatives and medicaments containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4065593A true AU4065593A (en) | 1993-12-13 |
Family
ID=6458213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU40655/93A Abandoned AU4065593A (en) | 1992-05-10 | 1993-05-07 | Novel tricyclic thiazolo and thiazino derivatives and anti-viral medicaments containing them |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0640088B1 (en) |
JP (1) | JPH08500090A (en) |
AT (1) | ATE143964T1 (en) |
AU (1) | AU4065593A (en) |
CA (1) | CA2134200A1 (en) |
DE (2) | DE4214830A1 (en) |
WO (1) | WO1993023407A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007059125A2 (en) * | 2005-11-15 | 2007-05-24 | Bristol-Myers Squibb Company | Hiv integrase inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA986932A (en) * | 1970-08-27 | 1976-04-06 | Shigeho Inaba | Process for preparing quinazoline derivatives |
DE4103177A1 (en) * | 1991-02-02 | 1992-08-06 | Boehringer Mannheim Gmbh | THIAZOLO- (2,3-A) ISOINDOL DERIVATIVES AND MEDICAMENTS CONTAINING THEREOF |
IL102764A0 (en) * | 1991-08-16 | 1993-01-31 | Merck & Co Inc | Quinazoline derivatives,and pharmaceutical compositions containing them |
-
1992
- 1992-05-10 DE DE4214830A patent/DE4214830A1/en not_active Withdrawn
-
1993
- 1993-05-07 AT AT93909921T patent/ATE143964T1/en not_active IP Right Cessation
- 1993-05-07 CA CA002134200A patent/CA2134200A1/en not_active Abandoned
- 1993-05-07 JP JP5519844A patent/JPH08500090A/en active Pending
- 1993-05-07 AU AU40655/93A patent/AU4065593A/en not_active Abandoned
- 1993-05-07 DE DE59304138T patent/DE59304138D1/en not_active Expired - Fee Related
- 1993-05-07 EP EP93909921A patent/EP0640088B1/en not_active Expired - Lifetime
- 1993-05-07 WO PCT/EP1993/001125 patent/WO1993023407A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0640088B1 (en) | 1996-10-09 |
DE59304138D1 (en) | 1996-11-14 |
EP0640088A1 (en) | 1995-03-01 |
JPH08500090A (en) | 1996-01-09 |
CA2134200A1 (en) | 1993-11-25 |
ATE143964T1 (en) | 1996-10-15 |
WO1993023407A1 (en) | 1993-11-25 |
DE4214830A1 (en) | 1993-11-11 |
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