ZA925470B - Process and chiral intermediates for thiazole antidiabetics - Google Patents

Process and chiral intermediates for thiazole antidiabetics

Info

Publication number
ZA925470B
ZA925470B ZA925470A ZA925470A ZA925470B ZA 925470 B ZA925470 B ZA 925470B ZA 925470 A ZA925470 A ZA 925470A ZA 925470 A ZA925470 A ZA 925470A ZA 925470 B ZA925470 B ZA 925470B
Authority
ZA
South Africa
Prior art keywords
antidiabetics
thiazole
chiral intermediates
chiral
intermediates
Prior art date
Application number
ZA925470A
Other languages
English (en)
Inventor
George J Quallich
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA925470B publication Critical patent/ZA925470B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA925470A 1991-07-22 1992-07-21 Process and chiral intermediates for thiazole antidiabetics ZA925470B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73354891A 1991-07-22 1991-07-22

Publications (1)

Publication Number Publication Date
ZA925470B true ZA925470B (en) 1994-01-21

Family

ID=24948077

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925470A ZA925470B (en) 1991-07-22 1992-07-21 Process and chiral intermediates for thiazole antidiabetics

Country Status (17)

Country Link
US (1) US5576442A (es)
EP (1) EP0641331A1 (es)
JP (1) JP2672029B2 (es)
KR (1) KR100214907B1 (es)
AU (1) AU660187B2 (es)
CA (1) CA2111446C (es)
FI (1) FI940307A (es)
HU (1) HUT70422A (es)
IE (1) IE922358A1 (es)
IL (1) IL102575A (es)
MX (1) MX9204277A (es)
NO (1) NO940226D0 (es)
NZ (1) NZ243652A (es)
PT (1) PT100709B (es)
TW (1) TW199892B (es)
WO (1) WO1993002061A1 (es)
ZA (1) ZA925470B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687149B1 (fr) * 1992-02-12 1995-11-03 Roussel Uclaf Nouveaux esters pyrethrinouides derives d'alcools thiazoliques, leur procede de preparation et leur application comme pesticides.
CA2167287A1 (en) * 1993-07-16 1995-01-26 George Joseph Quallich Enantioselective process for thiazole intermediates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3621775A1 (de) * 1986-03-13 1988-01-07 Thomae Gmbh Dr K Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US4886814A (en) * 1986-03-13 1989-12-12 Dr. Karl Thomas Gmbh Substituted thiazoles and oxazoles and 2-hydroxy-morpholines
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
ES2123562T3 (es) * 1991-07-22 1999-01-16 Pfizer Procedimiento para la preparacion de (s)-4-(3-(5-metil-2-fenil-4-oxazolil)-1-hidroxipropil)bromobenceno.

Also Published As

Publication number Publication date
HU9400187D0 (en) 1994-05-30
NO940226L (no) 1994-01-21
NZ243652A (en) 1994-02-25
JPH06505026A (ja) 1994-06-09
NO940226D0 (no) 1994-01-21
IE922358A1 (en) 1993-01-27
KR100214907B1 (ko) 1999-08-02
MX9204277A (es) 1993-02-01
JP2672029B2 (ja) 1997-11-05
CA2111446C (en) 1997-12-16
US5576442A (en) 1996-11-19
HUT70422A (en) 1995-10-30
TW199892B (es) 1993-02-11
AU2306392A (en) 1993-02-23
CA2111446A1 (en) 1993-02-04
WO1993002061A1 (en) 1993-02-04
PT100709B (pt) 1999-07-30
AU660187B2 (en) 1995-06-15
IL102575A (en) 1996-03-31
PT100709A (pt) 1993-09-30
IL102575A0 (en) 1993-01-14
FI940307A0 (fi) 1994-01-21
EP0641331A1 (en) 1995-03-08
FI940307A (fi) 1994-01-21

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