ZA922873B - N - hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]-ureas as lipoxygenase inhibitors - Google Patents
N - hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]-ureas as lipoxygenase inhibitorsInfo
- Publication number
- ZA922873B ZA922873B ZA922873A ZA922873A ZA922873B ZA 922873 B ZA922873 B ZA 922873B ZA 922873 A ZA922873 A ZA 922873A ZA 922873 A ZA922873 A ZA 922873A ZA 922873 B ZA922873 B ZA 922873B
- Authority
- ZA
- South Africa
- Prior art keywords
- halophenylthio
- enyl
- ureas
- prop
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
- C07C323/47—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69020491A | 1991-04-23 | 1991-04-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA922873B true ZA922873B (en) | 1993-10-21 |
Family
ID=24771539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA922873A ZA922873B (en) | 1991-04-23 | 1992-04-21 | N - hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]-ureas as lipoxygenase inhibitors |
Country Status (17)
Country | Link |
---|---|
US (1) | US5283361A (fi) |
EP (1) | EP0510948A1 (fi) |
JP (1) | JPH05117227A (fi) |
KR (1) | KR920019740A (fi) |
CN (1) | CN1066062A (fi) |
AU (1) | AU638641B2 (fi) |
BR (1) | BR9201452A (fi) |
CA (1) | CA2066508A1 (fi) |
CS (1) | CS119492A3 (fi) |
FI (1) | FI921786A (fi) |
HU (1) | HUT62557A (fi) |
IE (1) | IE921279A1 (fi) |
IL (1) | IL101625A0 (fi) |
MX (1) | MX9201808A (fi) |
NO (1) | NO921530L (fi) |
TW (1) | TW199141B (fi) |
ZA (1) | ZA922873B (fi) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05294921A (ja) * | 1992-04-17 | 1993-11-09 | Pfizer Pharmaceut Co Ltd | 新規なフェニル置換シクロアルキル尿素誘導体および組成物 |
JP2756732B2 (ja) * | 1993-12-22 | 1998-05-25 | ファイザー製薬株式会社 | リポキシゲナーゼ阻害剤としてのフェニルチオフェニルシクロアルケニルヒドロキシ尿素 |
US5891460A (en) * | 1995-06-07 | 1999-04-06 | University Of Southern California University Park Campus | Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof |
JP3929140B2 (ja) * | 1997-10-27 | 2007-06-13 | 日本碍子株式会社 | 耐蝕性部材およびその製造方法 |
AU2010241567B2 (en) | 2009-04-29 | 2013-10-31 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical compositions comprising EPA and a cardiovascular agent and methods of using the same |
CN102659637B (zh) * | 2012-05-21 | 2014-05-14 | 上海大学 | 一种制备双羟基脲的新方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE80611T1 (de) * | 1985-03-16 | 1992-10-15 | Wellcome Found | Aryl-derivate. |
US5185363A (en) * | 1986-04-25 | 1993-02-09 | Abbott Laboratories | Urea based lipoxygenase inhibiting compounds |
GB8619593D0 (en) * | 1986-08-12 | 1986-09-24 | Roussel Lab Ltd | Chemical compounds |
DE3882732T2 (de) * | 1987-02-10 | 1993-12-02 | Abbott Lab | Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen. |
DE69004119T2 (de) * | 1989-02-03 | 1994-03-24 | Wellcome Found | Entzündungshemmende Arylderivate. |
JPH04504261A (ja) * | 1989-03-30 | 1992-07-30 | アボツト・ラボラトリーズ | 尿素系リポキシゲナーゼ阻害化合物 |
US5130485A (en) * | 1991-04-23 | 1992-07-14 | Eli Lilly And Company | N-hydroxy-N-(3-(2-substituted phenyl)prop-2-enyl)ureas and thioureas useful as 5-lipoxygenase inhibiting agents |
-
1992
- 1992-04-08 US US07/865,005 patent/US5283361A/en not_active Expired - Fee Related
- 1992-04-16 IL IL101625A patent/IL101625A0/xx unknown
- 1992-04-17 CS CS921194A patent/CS119492A3/cs unknown
- 1992-04-17 TW TW081103011A patent/TW199141B/zh active
- 1992-04-20 MX MX9201808A patent/MX9201808A/es unknown
- 1992-04-20 BR BR929201452A patent/BR9201452A/pt not_active Application Discontinuation
- 1992-04-21 ZA ZA922873A patent/ZA922873B/xx unknown
- 1992-04-21 AU AU15009/92A patent/AU638641B2/en not_active Ceased
- 1992-04-21 KR KR1019920006703A patent/KR920019740A/ko not_active Application Discontinuation
- 1992-04-21 CA CA002066508A patent/CA2066508A1/en not_active Abandoned
- 1992-04-21 NO NO92921530A patent/NO921530L/no unknown
- 1992-04-22 JP JP4102841A patent/JPH05117227A/ja not_active Withdrawn
- 1992-04-22 IE IE127992A patent/IE921279A1/en not_active Application Discontinuation
- 1992-04-22 FI FI921786A patent/FI921786A/fi not_active Application Discontinuation
- 1992-04-22 EP EP92303615A patent/EP0510948A1/en not_active Ceased
- 1992-04-22 HU HU9201343A patent/HUT62557A/hu unknown
- 1992-04-22 CN CN92102892A patent/CN1066062A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
AU638641B2 (en) | 1993-07-01 |
CS119492A3 (en) | 1992-12-16 |
BR9201452A (pt) | 1992-12-01 |
IL101625A0 (en) | 1992-12-30 |
US5283361A (en) | 1994-02-01 |
TW199141B (fi) | 1993-02-01 |
CA2066508A1 (en) | 1992-10-24 |
NO921530L (no) | 1992-10-26 |
FI921786A (fi) | 1992-10-24 |
IE921279A1 (en) | 1992-11-04 |
MX9201808A (es) | 1994-05-31 |
FI921786A0 (fi) | 1992-04-22 |
EP0510948A1 (en) | 1992-10-28 |
AU1500992A (en) | 1992-10-29 |
CN1066062A (zh) | 1992-11-11 |
KR920019740A (ko) | 1992-11-19 |
HUT62557A (en) | 1993-05-28 |
HU9201343D0 (en) | 1992-07-28 |
JPH05117227A (ja) | 1993-05-14 |
NO921530D0 (no) | 1992-04-21 |
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